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Items: 15

1.

A pilot study to clinically evaluate the role of herbomineral compound "Rakatchap Har" in the management of essential hypertension.

Nandha R, Singh H, Moudgill P, Kular G.

Ayu. 2011 Jul;32(3):329-32. doi: 10.4103/0974-8520.93908.

2.

Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake.

Green CJ, Göransson O, Kular GS, Leslie NR, Gray A, Alessi DR, Sakamoto K, Hundal HS.

J Biol Chem. 2008 Oct 10;283(41):27653-67. doi: 10.1074/jbc.M802623200. Epub 2008 Jul 31.

3.

TAK1-binding protein 1 is a pseudophosphatase.

Conner SH, Kular G, Peggie M, Shepherd S, Schüttelkopf AW, Cohen P, Van Aalten DM.

Biochem J. 2006 Nov 1;399(3):427-34.

4.

Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding.

Komander D, Kular G, Deak M, Alessi DR, van Aalten DM.

J Biol Chem. 2005 May 13;280(19):18797-802. Epub 2005 Mar 1.

5.

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

Komander D, Fairservice A, Deak M, Kular GS, Prescott AR, Peter Downes C, Safrany ST, Alessi DR, van Aalten DM.

EMBO J. 2004 Oct 13;23(20):3918-28. Epub 2004 Sep 30.

6.
7.

FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P.

Godi A, Di Campli A, Konstantakopoulos A, Di Tullio G, Alessi DR, Kular GS, Daniele T, Marra P, Lucocq JM, De Matteis MA.

Nat Cell Biol. 2004 May;6(5):393-404. Epub 2004 Apr 25.

PMID:
15107860
8.

Interactions of LY333531 and other bisindolyl maleimide inhibitors with PDK1.

Komander D, Kular GS, Schüttelkopf AW, Deak M, Prakash KR, Bain J, Elliott M, Garrido-Franco M, Kozikowski AP, Alessi DR, van Aalten DM.

Structure. 2004 Feb;12(2):215-26.

9.
10.

Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition.

Komander D, Kular GS, Bain J, Elliott M, Alessi DR, Van Aalten DM.

Biochem J. 2003 Oct 15;375(Pt 2):255-62.

11.

Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in vitro.

Kular GS, Chaudhary A, Prestwich G, Swigart P, Wetzker R, Cockcroft S.

Adv Enzyme Regul. 2002;42:53-61. No abstract available.

PMID:
12123706
12.

Protein lipid overlay assay.

Dowler S, Kular G, Alessi DR.

Sci STKE. 2002 Apr 23;2002(129):pl6.

PMID:
11972359
13.
14.

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR.

Biochem J. 2000 Oct 1;351(Pt 1):19-31.

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