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Items: 1 to 50 of 1227

1.

Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease.

Beck MW, Derrick JS, Suh JM, Kim M, Korshavn KJ, Kerr RA, Cho WJ, Larsen SD, Ruotolo BT, Ramamoorthy A, Lim MH.

ChemMedChem. 2017 Nov 22;12(22):1828-1838. doi: 10.1002/cmdc.201700456. Epub 2017 Oct 9.

2.

How a Mutation that Slows Aging Can Also Disproportionately Extend End-of-Life Decrepitude.

Podshivalova K, Kerr RA, Kenyon C.

Cell Rep. 2017 Apr 18;19(3):441-450. doi: 10.1016/j.celrep.2017.03.062.

3.

Structural and Mechanistic Insights into Development of Chemical Tools to Control Individual and Inter-Related Pathological Features in Alzheimer's Disease.

Lee HJ, Korshavn KJ, Nam Y, Kang J, Paul TJ, Kerr RA, Youn IS, Ozbil M, Kim KS, Ruotolo BT, Prabhakar R, Ramamoorthy A, Lim MH.

Chemistry. 2017 Feb 21;23(11):2706-2715. doi: 10.1002/chem.201605401. Epub 2017 Jan 26.

4.

Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer's disease.

Beck MW, Derrick JS, Kerr RA, Oh SB, Cho WJ, Lee SJ, Ji Y, Han J, Tehrani ZA, Suh N, Kim S, Larsen SD, Kim KS, Lee JY, Ruotolo BT, Lim MH.

Nat Commun. 2016 Oct 13;7:13115. doi: 10.1038/ncomms13115.

5.

Importance of the Dimethylamino Functionality on a Multifunctional Framework for Regulating Metals, Amyloid-β, and Oxidative Stress in Alzheimer's Disease.

Derrick JS, Kerr RA, Korshavn KJ, McLane MJ, Kang J, Nam E, Ramamoorthy A, Ruotolo BT, Lim MH.

Inorg Chem. 2016 May 16;55(10):5000-13. doi: 10.1021/acs.inorgchem.6b00525. Epub 2016 Apr 27.

PMID:
27119456
6.

Complex Formed between Intramembrane Metalloprotease SpoIVFB and Its Substrate, Pro-σK.

Zhang Y, Halder S, Kerr RA, Parrell D, Ruotolo B, Kroos L.

J Biol Chem. 2016 May 6;291(19):10347-62. doi: 10.1074/jbc.M116.715508. Epub 2016 Mar 7.

7.

A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms.

Derrick JS, Kerr RA, Nam Y, Oh SB, Lee HJ, Earnest KG, Suh N, Peck KL, Ozbil M, Korshavn KJ, Ramamoorthy A, Prabhakar R, Merino EJ, Shearer J, Lee JY, Ruotolo BT, Lim MH.

J Am Chem Soc. 2015 Nov 25;137(46):14785-97. doi: 10.1021/jacs.5b10043. Epub 2015 Nov 17.

8.

A rationally designed small molecule for identifying an in vivo link between metal-amyloid-β complexes and the pathogenesis of Alzheimer's disease.

Beck MW, Oh SB, Kerr RA, Lee HJ, Kim SH, Kim S, Jang M, Ruotolo BT, Lee JY, Lim MH.

Chem Sci. 2015 Mar 1;6(3):1879-1886. doi: 10.1039/c4sc03239j. Epub 2015 Jan 27.

9.

A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans.

Butler VJ, Branicky R, Yemini E, Liewald JF, Gottschalk A, Kerr RA, Chklovskii DB, Schafer WR.

J R Soc Interface. 2015 Jan 6;12(102):20140963.

10.

Planetary science. NASA to researchers: sell your mission or be terminated.

Kerr RA.

Science. 2014 Apr 11;344(6180):138-9. doi: 10.1126/science.344.6180.138. No abstract available.

PMID:
24723588
11.

Planetary science. Cassini plumbs the depths of the Enceladus sea.

Kerr RA.

Science. 2014 Apr 4;344(6179):17. doi: 10.1126/science.344.6179.17. No abstract available.

PMID:
24700829
12.

Planetary science. Search for martian life clears another hurdle.

Kerr RA.

Science. 2014 Mar 28;343(6178):1419. doi: 10.1126/science.343.6178.1419. No abstract available.

PMID:
24675932
13.

Discovery of brainwide neural-behavioral maps via multiscale unsupervised structure learning.

Vogelstein JT, Park Y, Ohyama T, Kerr RA, Truman JW, Priebe CE, Zlatic M.

Science. 2014 Apr 25;344(6182):386-92. doi: 10.1126/science.1250298. Epub 2014 Mar 27.

14.

Paleoclimate. How Earth can cool without plunging into a deep freeze.

Kerr RA.

Science. 2014 Mar 14;343(6176):1189. doi: 10.1126/science.343.6176.1189. No abstract available.

PMID:
24626909
15.

Atmospheric evolution. New look at ancient mineral could scrap a test for early oxygen.

Kerr RA.

Science. 2014 Feb 28;343(6174):960. doi: 10.1126/science.343.6174.960. No abstract available.

PMID:
24578559
16.

Climate change. Atlantic current can shut down for centuries, disrupting climate.

Kerr RA.

Science. 2014 Feb 21;343(6173):831. doi: 10.1126/science.343.6173.831. No abstract available.

PMID:
24558140
17.

The coming copper peak.

Kerr RA.

Science. 2014 Feb 14;343(6172):722-4. doi: 10.1126/science.343.6172.722. No abstract available.

PMID:
24531951
18.

Meteorology. Southern Hemisphere storms pulsate to a 25-day beat, new papers show.

Kerr RA.

Science. 2014 Feb 7;343(6171):588. doi: 10.1126/science.343.6171.588. No abstract available.

PMID:
24503825
19.

Paleontology. Mega-eruptions drove the mother of mass extinctions.

Kerr RA.

Science. 2013 Dec 20;342(6165):1424. doi: 10.1126/science.342.6165.1424. No abstract available.

PMID:
24357278
20.

Planetary science. New results send Mars rover on a quest for ancient life.

Kerr RA.

Science. 2013 Dec 13;342(6164):1300-1. doi: 10.1126/science.342.6164.1300. No abstract available.

PMID:
24337267
21.

Climate change. Humans fueled global warming millennia ago.

Kerr RA.

Science. 2013 Nov 22;342(6161):918. doi: 10.1126/science.342.6161.918. No abstract available.

PMID:
24264968
22.

Climate change. In the hot seat.

Kerr RA.

Science. 2013 Nov 8;342(6159):688-9. doi: 10.1126/science.342.6159.688. No abstract available.

PMID:
24202158
23.

A neuron-based screening platform for optimizing genetically-encoded calcium indicators.

Wardill TJ, Chen TW, Schreiter ER, Hasseman JP, Tsegaye G, Fosque BF, Behnam R, Shields BC, Ramirez M, Kimmel BE, Kerr RA, Jayaraman V, Looger LL, Svoboda K, Kim DS.

PLoS One. 2013 Oct 14;8(10):e77728. doi: 10.1371/journal.pone.0077728. eCollection 2013.

24.

Roving into martian waters.

Kerr RA.

Science. 2013 Oct 18;342(6156):304-6. doi: 10.1126/science.342.6156.304. No abstract available.

PMID:
24136947
25.

A stronger IPCC report.

Kerr RA.

Science. 2013 Oct 4;342(6154):23. doi: 10.1126/science.342.6154.23-b. No abstract available.

PMID:
24092707
26.

Climate science. The IPCC gains confidence in key forecast.

Kerr RA.

Science. 2013 Oct 4;342(6154):23-4. doi: 10.1126/science.342.6154.23-a. No abstract available.

PMID:
24092706
27.

Planetary science. It's official--Voyager has left the solar system.

Kerr RA.

Science. 2013 Sep 13;341(6151):1158-9. doi: 10.1126/science.341.6151.1158. No abstract available.

PMID:
24030991
28.

Planetary science. Taking the life out of Titan.

Kerr RA.

Science. 2013 Aug 30;341(6149):949-50. doi: 10.1126/science.341.6149.949. No abstract available.

PMID:
23990537
29.

High-throughput analysis of stimulus-evoked behaviors in Drosophila larva reveals multiple modality-specific escape strategies.

Ohyama T, Jovanic T, Denisov G, Dang TC, Hoffmann D, Kerr RA, Zlatic M.

PLoS One. 2013 Aug 20;8(8):e71706. doi: 10.1371/journal.pone.0071706. eCollection 2013.

30.

Solar system exploration. Pluto, the last planetary first.

Kerr RA.

Science. 2013 Aug 16;341(6147):708-9. doi: 10.1126/science.341.6147.708. No abstract available.

PMID:
23950509
31.

Paleoclimatology. How to make a great ice age, again and again and again.

Kerr RA.

Science. 2013 Aug 9;341(6146):599. doi: 10.1126/science.341.6146.599. No abstract available.

PMID:
23929957
32.

Space physics. The savage radiation of the Van Allen belts is homegrown.

Kerr RA.

Science. 2013 Jul 26;341(6144):331. doi: 10.1126/science.341.6144.331. No abstract available.

PMID:
23888013
33.

Ultrasensitive fluorescent proteins for imaging neuronal activity.

Chen TW, Wardill TJ, Sun Y, Pulver SR, Renninger SL, Baohan A, Schreiter ER, Kerr RA, Orger MB, Jayaraman V, Looger LL, Svoboda K, Kim DS.

Nature. 2013 Jul 18;499(7458):295-300. doi: 10.1038/nature12354.

34.

Planetary science. Meteorite mystery edges closer to an answer--or the end of a field.

Kerr RA.

Science. 2013 Jul 12;341(6142):126-7. doi: 10.1126/science.341.6142.126. No abstract available.

PMID:
23846888
35.

Seismology. Some earthquakes warn that they are about to strike.

Kerr RA.

Science. 2013 Jul 12;341(6142):117-8. doi: 10.1126/science.341.6142.117. No abstract available.

PMID:
23846882
36.

Solid-Earth science. Geophysical exploration linking deep Earth and backyard geology.

Kerr RA.

Science. 2013 Jun 14;340(6138):1283-5. doi: 10.1126/science.340.6138.1283. No abstract available.

PMID:
23766309
37.

Planetary exploration. Radiation will make astronauts' trip to Mars even riskier.

Kerr RA.

Science. 2013 May 31;340(6136):1031. doi: 10.1126/science.340.6136.1031. No abstract available.

PMID:
23723213
38.

Glaciology. Melting glaciers, not just ice sheets, stoking sea-level rise.

Kerr RA.

Science. 2013 May 17;340(6134):798. doi: 10.1126/science.340.6134.798. No abstract available.

PMID:
23687019
39.

NASA. Planetary scientists casting doubt on feasibility of plan to corral asteroid.

Kerr RA.

Science. 2013 May 10;340(6133):668-9. doi: 10.1126/science.340.6133.668. No abstract available.

PMID:
23661730
40.

Exoplanets. Kepler snags super-Earth-size planet squarely in a habitable zone.

Kerr RA.

Science. 2013 Apr 19;340(6130):262. doi: 10.1126/science.340.6130.262. No abstract available.

PMID:
23599453
41.

Lunar and Planetary Science Conference. Snapshots from the meeting.

Kerr RA.

Science. 2013 Apr 12;340(6129):139. doi: 10.1126/science.340.6129.139-b. No abstract available.

PMID:
23580507
42.

Lunar and planetary science conference. More support for an ocean in Enceladus.

Kerr RA.

Science. 2013 Apr 12;340(6129):139. doi: 10.1126/science.340.6129.139-a. No abstract available.

PMID:
23580506
43.

Lunar and planetary science conference. Pesky perchlorates all over Mars.

Kerr RA.

Science. 2013 Apr 12;340(6129):138. doi: 10.1126/science.340.6129.138-b. No abstract available.

PMID:
23580505
44.

Lunar and planetary science conference. The mystery of our moon's gravitational bumps solved?

Kerr RA.

Science. 2013 Apr 12;340(6129):138-9. doi: 10.1126/science.340.6129.138-a. No abstract available.

PMID:
23580504
45.

The deep Earth machine is coming together.

Kerr RA.

Science. 2013 Apr 5;340(6128):22-4. doi: 10.1126/science.340.6128.22. No abstract available. Erratum in: Science. 2013 May 31;340(6136):1042.

PMID:
23559231
46.

Planetary science. Life could have thrived on Mars, but did it? Curiosity still has no clue.

Kerr RA.

Science. 2013 Mar 22;339(6126):1373. doi: 10.1126/science.339.6126.1373. No abstract available.

PMID:
23520089
47.

Global change. Forecasting regional climate change flunks its first test.

Kerr RA.

Science. 2013 Feb 8;339(6120):638. doi: 10.1126/science.339.6120.638. No abstract available.

PMID:
23393237
48.

Global change. The psst that pierced the sky is now churning the sea.

Kerr RA.

Science. 2013 Feb 1;339(6119):500. doi: 10.1126/science.339.6119.500. No abstract available.

PMID:
23371987
49.

Global warming. Soot is warming the world even more than thought.

Kerr RA.

Science. 2013 Jan 25;339(6118):382. doi: 10.1126/science.339.6118.382. No abstract available.

PMID:
23349261
50.

Fall meeting of the American Geophysical Union. Snapshots from the meeting.

Kerr RA.

Science. 2012 Dec 21;338(6114):1523. doi: 10.1126/science.338.6114.1523-b. No abstract available.

PMID:
23258863

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