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Building Bridges through Science. Lissek T et al. Neuron. (2017)

Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration. Yester JW et al. Curr Cardiol Rep. (2017)

Humanin is an endogenous activator of chaperone-mediated autophagy. Gong Z et al. J Cell Biol. (2018)

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Items: 1 to 50 of 374


Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment.

Liu H, Zhang CH, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML, Kühn B.

Sci Transl Med. 2019 Oct 9;11(513). pii: eaaw6419. doi: 10.1126/scitranslmed.aaw6419.


Assessing peripheral fibers, pain sensitivity, central sensitization, and descending inhibition in Native Americans: main findings from the Oklahoma Study of Native American Pain Risk (OK-SNAP).

Rhudy JL, Lannon EW, Kuhn BL, Palit S, Payne MF, Sturycz CA, Hellman N, Güereca YM, Toledo TA, Huber F, Demuth MJ, Hahn BJ, Chaney JM, Shadlow JO.

Pain. 2019 Oct 7. doi: 10.1097/j.pain.0000000000001715. [Epub ahead of print]


The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior in rats.

Campus P, Covelo IR, Kim Y, Parsegian A, Kuhn BN, Lopez SA, Neumaier JF, Ferguson SM, Solberg Woods LC, Sarter M, Flagel SB.

Elife. 2019 Sep 10;8. pii: e49041. doi: 10.7554/eLife.49041.


Improving Mechanical Ventilator Clinical Decision Support Systems with a Machine Learning Classifier for Determining Ventilator Mode.

Rehm GB, Kuhn BT, Nguyen J, Anderson NR, Chuah CN, Adams JY.

Stud Health Technol Inform. 2019 Aug 21;264:318-322. doi: 10.3233/SHTI190235.


Primer to Voltage Imaging With ANNINE Dyes and Two-Photon Microscopy.

Kuhn B, Roome CJ.

Front Cell Neurosci. 2019 Jul 16;13:321. doi: 10.3389/fncel.2019.00321. eCollection 2019. Review.


Viruses and non-allergen environmental triggers in asthma.

Chau-Etchepare F, Hoerger JL, Kuhn BT, Zeki AA, Haczku A, Louie S, Kenyon NJ, Davis CE, Schivo M.

J Investig Med. 2019 Oct;67(7):1029-1041. doi: 10.1136/jim-2019-001000. Epub 2019 Jul 27. Review.


Conformation space of a heterodimeric ABC exporter under turnover conditions.

Hofmann S, Januliene D, Mehdipour AR, Thomas C, Stefan E, Brüchert S, Kuhn BT, Geertsma ER, Hummer G, Tampé R, Moeller A.

Nature. 2019 Jul;571(7766):580-583. doi: 10.1038/s41586-019-1391-0. Epub 2019 Jul 17.


Regenerating Hearts by Arresting Development With Hypothyroidism.

Lal S, Kühn B.

Circ Res. 2019 Jun 7;124(12):1725-1726. doi: 10.1161/CIRCRESAHA.119.315106. Epub 2019 Jun 6. No abstract available.


Nonuniform Fourier-decomposition MRI for ventilation- and perfusion-weighted imaging of the lung.

Bondesson D, Schneider MJ, Gaass T, Kühn B, Bauman G, Dietrich O, Dinkel J.

Magn Reson Med. 2019 Oct;82(4):1312-1321. doi: 10.1002/mrm.27803. Epub 2019 May 20.


Anger Inhibition and Pain Modulation.

Toledo TA, Hellman N, Lannon EW, Sturycz CA, Kuhn BL, Payne MF, Palit S, Güereca YM, Shadlow JO, Rhudy JL.

Ann Behav Med. 2019 Apr 22. pii: kaz016. doi: 10.1093/abm/kaz016. [Epub ahead of print]


Creation of a Robust and Generalizable Machine Learning Classifier for Patient Ventilator Asynchrony.

Rehm GB, Han J, Kuhn BT, Delplanque JP, Anderson NR, Adams JY, Chuah CN.

Methods Inf Med. 2018 Sep;57(4):208-219. doi: 10.3414/ME17-02-0012. Epub 2018 Sep 24.


Conditioned Pain Modulation in Sexual Assault Survivors.

Hellman N, Sturycz CA, Lannon EW, Kuhn BL, Güereca YM, Toledo TA, Payne MF, Huber FA, Demuth M, Palit S, Shadlow JO, Rhudy JL.

J Pain. 2019 Sep;20(9):1027-1039. doi: 10.1016/j.jpain.2019.02.012. Epub 2019 Feb 27.


Chemotherapy response of pancreatic cancer by diffusion-weighted imaging (DWI) and intravoxel incoherent motion DWI (IVIM-DWI) in an orthotopic mouse model.

Wu L, Li J, Fu C, Kühn B, Wang X.

MAGMA. 2019 Aug;32(4):501-509. doi: 10.1007/s10334-019-00745-3. Epub 2019 Mar 1.


Sensory, Affective, and Catastrophizing Reactions to Multiple Stimulus Modalities: Results from the Oklahoma Study of Native American Pain Risk.

Rhudy JL, Lannon EW, Kuhn BL, Palit S, Payne MF, Sturycz CA, Hellman N, Güereca YM, Toledo TA, Coleman HB, Thompson KA, Fisher JM, Herbig SP, Barnoski KB, Chee L, Shadlow JO.

J Pain. 2019 Aug;20(8):965-979. doi: 10.1016/j.jpain.2019.02.009. Epub 2019 Feb 22.


Race/Ethnicity Does Not Moderate the Relationship Between Adverse Life Experiences and Temporal Summation of the Nociceptive Flexion Reflex and Pain: Results From the Oklahoma Study of Native American Pain Risk.

Sturycz CA, Hellman N, Payne MF, Kuhn BL, Hahn B, Lannon EW, Palit S, Güereca YM, Toledo TA, Shadlow JO, Rhudy JL.

J Pain. 2019 Aug;20(8):941-955. doi: 10.1016/j.jpain.2019.02.006. Epub 2019 Feb 15.


Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling.

Bossler F, Kuhn BJ, Günther T, Kraemer SJ, Khalkar P, Adrian S, Lohrey C, Holzer A, Shimobayashi M, Dürst M, Mayer A, Rösl F, Grundhoff A, Krijgsveld J, Hoppe-Seyler K, Hoppe-Seyler F.

MBio. 2019 Feb 12;10(1). pii: e02323-18. doi: 10.1128/mBio.02323-18.


A 51-Year-Old Man With Unresolved Pulmonary Infiltrates Following Streptococcus pneumoniae Pneumonia.

Pugashetti JV, Adams JY, Zeki AA, Kuhn BT.

Chest. 2019 Feb;155(2):e47-e50. doi: 10.1016/j.chest.2018.08.1064.


Diagnostic accuracy of 3D breath-hold MR cholangiography using compressed sensing acceleration in visualizing non-dilated biliary system in living donor liver transplantation donors.

Ono A, Arizono S, Kohno S, Nakai H, Isoda H, Kühn B, Togashi K.

Acta Radiol. 2019 Oct;60(10):1209-1215. doi: 10.1177/0284185118822631. Epub 2019 Jan 12. No abstract available.


An Unusual Case of Tertiary Syphilis Behaving Like Tongue Squamous Cell Carcinoma.

Solis RN, Kuhn BT, Farwell DG.

J Investig Med High Impact Case Rep. 2018 Dec 20;6:2324709618820355. doi: 10.1177/2324709618820355. eCollection 2018 Jan-Dec.


DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.

Richter H, Satz AL, Bedoucha M, Buettelmann B, Petersen AC, Harmeier A, Hermosilla R, Hochstrasser R, Burger D, Gsell B, Gasser R, Huber S, Hug MN, Kocer B, Kuhn B, Ritter M, Rudolph MG, Weibel F, Molina-David J, Kim JJ, Santos JV, Stihle M, Georges GJ, Bonfil RD, Fridman R, Uhles S, Moll S, Faul C, Fornoni A, Prunotto M.

ACS Chem Biol. 2019 Jan 18;14(1):37-49. doi: 10.1021/acschembio.8b00866. Epub 2018 Dec 16.


Imaging Ca2+ Concentration and pH in Nanopores/Channels of Protein Crystals.

Mori K, Kuhn B.

J Phys Chem B. 2018 Oct 25;122(42):9646-9653. doi: 10.1021/acs.jpcb.8b07099. Epub 2018 Oct 11.


Sphingosine-1-phosphate (S1P) induces potent anti-inflammatory effects in vitro and in vivo by S1P receptor 4-mediated suppression of 5-lipoxygenase activity.

Fettel J, Kühn B, Guillen NA, Sürün D, Peters M, Bauer R, Angioni C, Geisslinger G, Schnütgen F, Meyer Zu Heringdorf D, Werz O, Meybohm P, Zacharowski K, Steinhilber D, Roos J, Maier TJ.

FASEB J. 2019 Feb;33(2):1711-1726. doi: 10.1096/fj.201800221R. Epub 2018 Sep 6.


Efficient Industrial Synthesis of the MDM2 Antagonist Idasanutlin via a Cu(I)-catalyzed [3+2] Asymmetric Cycloaddition.

Fishlock D, Diodone R, Hildbrand S, Kuhn B, Mössner C, Peters C, Rege PD, Rimmler G, Schantz M.

Chimia (Aarau). 2018 Aug 22;72(7):492-500. doi: 10.2533/chimia.2018.492.


Simultaneous dendritic voltage and calcium imaging and somatic recording from Purkinje neurons in awake mice.

Roome CJ, Kuhn B.

Nat Commun. 2018 Aug 23;9(1):3388. doi: 10.1038/s41467-018-05900-3.


Correction to: Outcomes of a Behavioral Intervention for Sleep Disturbances in Children with Autism Spectrum Disorder.

Sanberg SA, Kuhn BR, Kennedy AE.

J Autism Dev Disord. 2018 Dec;48(12):4278-4286. doi: 10.1007/s10803-018-3705-8.


Motion-corrected multiparametric renal arterial spin labelling at 3 T: reproducibility and effect of vasodilator challenge.

Shirvani S, Tokarczuk P, Statton B, Quinlan M, Berry A, Tomlinson J, Weale P, Kühn B, O'Regan DP.

Eur Radiol. 2019 Jan;29(1):232-240. doi: 10.1007/s00330-018-5628-3. Epub 2018 Jul 10.


Elucidation of chemical modifier reactivity towards peptides and proteins and the analysis of specific fragmentation by matrix-assisted laser desorption/ionization collision-induced dissociation tandem mass spectrometry.

Rühl M, Kühn B, Roos J, Maier TJ, Steinhilber D, Karas M.

Rapid Commun Mass Spectrom. 2019 May;33 Suppl 1:40-49. doi: 10.1002/rcm.8223. Epub 2018 Aug 12.


Outcomes of a Behavioral Intervention for Sleep Disturbances in Children with Autism Spectrum Disorder.

Sanberg SA, Kuhn BR, Kennedy AE.

J Autism Dev Disord. 2018 Dec;48(12):4250-4277. doi: 10.1007/s10803-018-3644-4. Erratum in: J Autism Dev Disord. 2018 Aug 16;:.


Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells.

Kühn B, Brat C, Fettel J, Hellmuth N, Maucher IV, Bulut U, Hock KJ, Grimmer J, Manolikakes G, Rühl M, Kühn A, Zacharowski K, Matrone C, Urbschat A, Roos J, Steinhilber D, Maier TJ.

Biochem Pharmacol. 2018 Sep;155:48-60. doi: 10.1016/j.bcp.2018.06.014. Epub 2018 Jun 15.


The Influence of Placebo Analgesia Manipulations on Pain Report, the Nociceptive Flexion Reflex, and Autonomic Responses to Pain.

Rhudy JL, Güereca YM, Kuhn BL, Palit S, Flaten MA.

J Pain. 2018 Nov;19(11):1257-1274. doi: 10.1016/j.jpain.2018.04.012. Epub 2018 Jun 4.


2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design.

Giroud M, Kuhn B, Saint-Auret S, Kuratli C, Martin RE, Schuler F, Diederich F, Kaiser M, Brun R, Schirmeister T, Haap W.

J Med Chem. 2018 Apr 26;61(8):3370-3388. doi: 10.1021/acs.jmedchem.7b01870. Epub 2018 Apr 6.


Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.

Giroud M, Dietzel U, Anselm L, Banner D, Kuglstatter A, Benz J, Blanc JB, Gaufreteau D, Liu H, Lin X, Stich A, Kuhn B, Schuler F, Kaiser M, Brun R, Schirmeister T, Kisker C, Diederich F, Haap W.

J Med Chem. 2018 Apr 26;61(8):3350-3369. doi: 10.1021/acs.jmedchem.7b01869. Epub 2018 Apr 13.


Ligand channel in pharmacologically stabilized rhodopsin.

Mattle D, Kuhn B, Aebi J, Bedoucha M, Kekilli D, Grozinger N, Alker A, Rudolph MG, Schmid G, Schertler GFX, Hennig M, Standfuss J, Dawson RJP.

Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3640-3645. doi: 10.1073/pnas.1718084115. Epub 2018 Mar 19.


Microstructure evolution and dislocation behaviour in high chromium, fully ferritic steels strengthened by intermetallic Laves phases.

Lopez Barrilao J, Kuhn B, Wessel E.

Micron. 2018 May;108:11-18. doi: 10.1016/j.micron.2018.02.008. Epub 2018 Feb 23.


Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration.

Missinato MA, Saydmohammed M, Zuppo DA, Rao KS, Opie GW, Kühn B, Tsang M.

Development. 2018 Mar 6;145(5). pii: dev157206. doi: 10.1242/dev.157206.


Emotional Modulation of Pain and Spinal Nociception in Sexual Assault Survivors.

Hellman N, Kuhn BL, Lannon EW, Payne MF, Sturycz CA, Palit S, Shadlow JO, Rhudy JL.

Psychosom Med. 2018 Nov/Dec;80(9):861-868. doi: 10.1097/PSY.0000000000000567.


[Assessing the benefits of digital health solutions in the societal reimbursement context].

Albrecht UV, Kuhn B, Land J, Amelung VE, von Jan U.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2018 Mar;61(3):340-348. doi: 10.1007/s00103-018-2696-0. Review. German.


Management of Mechanical Ventilation in Decompensated Heart Failure.

Kuhn BT, Bradley LA, Dempsey TM, Puro AC, Adams JY.

J Cardiovasc Dev Dis. 2016 Dec 2;3(4). pii: E33. doi: 10.3390/jcdd3040033. Review.


Transient inactivation of the paraventricular nucleus of the thalamus enhances cue-induced reinstatement in goal-trackers, but not sign-trackers.

Kuhn BN, Klumpner MS, Covelo IR, Campus P, Flagel SB.

Psychopharmacology (Berl). 2018 Apr;235(4):999-1014. doi: 10.1007/s00213-017-4816-1. Epub 2017 Dec 28.


Which strategies might improve local primary healthcare in Germany? An explorative study from a local government point of view.

Kuhn B, Kleij KS, Liersch S, Steinhäuser J, Amelung V.

BMC Fam Pract. 2017 Dec 20;18(1):105. doi: 10.1186/s12875-017-0696-z.


D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies.

Gaieb Z, Liu S, Gathiaka S, Chiu M, Yang H, Shao C, Feher VA, Walters WP, Kuhn B, Rudolph MG, Burley SK, Gilson MK, Amaro RE.

J Comput Aided Mol Des. 2018 Jan;32(1):1-20. doi: 10.1007/s10822-017-0088-4. Epub 2017 Dec 4.


Humanin is an endogenous activator of chaperone-mediated autophagy.

Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, Kühn B, Cuervo AM, Muzumdar R.

J Cell Biol. 2018 Feb 5;217(2):635-647. doi: 10.1083/jcb.201606095. Epub 2017 Nov 29.


Building Bridges through Science.

Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, Belmonte C, Bertocchi I, Betz H, Blakemore C, Blanke O, Boehm-Sturm P, Bonhoeffer T, Bonifazi P, Brose N, Campolongo P, Celikel T, Chang CC, Chang TY, Citri A, Cline HT, Cortes JM, Cullen K, Dean K, Delgado-Garcia JM, Desroches M, Disterhoft JF, Dowling JE, Draguhn A, El-Khamisy SF, El Manira A, Enam SA, Encinas JM, Erramuzpe A, Esteban JA, Fariñas I, Fischer E, Fukunaga I, Gabilondo I, Ganten D, Gidon A, Gomez-Esteban JC, Greengard P, Grinevich V, Gruart A, Guillemin R, Hariri AR, Hassan B, Häusser M, Hayashi Y, Hussain NK, Jabbar AA, Jaber M, Jahn R, Janahi EM, Kabbaj M, Kettenmann H, Kindt M, Knafo S, Köhr G, Komai S, Krugers H, Kuhn B, Ghazal NL, Larkum ME, London M, Lutz B, Matute C, Martinez-Millan L, Maroun M, McGaugh J, Moustafa AA, Nasim A, Nave KA, Neher E, Nikolich K, Outeiro T, Palmer LM, Penagarikano O, Perez-Otano I, Pfaff DW, Poucet B, Rahman AU, Ramos-Cabrer P, Rashidy-Pour A, Roberts RJ, Rodrigues S, Sanes JR, Schaefer AT, Segal M, Segev I, Shafqat S, Siddiqui NA, Soreq H, Soriano-García E, Spanagel R, Sprengel R, Stuart G, Südhof TC, Tønnesen J, Treviño M, Uthman BM, Venter JC, Verkhratsky A, Weiss C, Wiesel TN, Yaksi E, Yizhar O, Young LJ, Young P, Zawia NH, Zugaza JL, Hasan MT.

Neuron. 2017 Nov 15;96(4):730-735. doi: 10.1016/j.neuron.2017.09.028.


Development and Validation of a Multi-Algorithm Analytic Platform to Detect Off-Target Mechanical Ventilation.

Adams JY, Lieng MK, Kuhn BT, Rehm GB, Guo EC, Taylor SL, Delplanque JP, Anderson NR.

Sci Rep. 2017 Nov 3;7(1):14980. doi: 10.1038/s41598-017-15052-x.


Development of a research-oriented system for collecting mechanical ventilator waveform data.

Rehm GB, Kuhn BT, Delplanque JP, Guo EC, Lieng MK, Nguyen J, Anderson NR, Adams JY.

J Am Med Inform Assoc. 2017 Oct 28. doi: 10.1093/jamia/ocx116. [Epub ahead of print]


Cosmetic Talc-Related Pulmonary Granulomatosis.

Jasuja S, Kuhn BT, Schivo M, Adams JY.

J Investig Med High Impact Case Rep. 2017 Sep 8;5(3):2324709617728527. doi: 10.1177/2324709617728527. eCollection 2017 Jul-Sep.


Identification, size classification and evolution of Laves phase precipitates in high chromium, fully ferritic steels.

Lopez Barrilao J, Kuhn B, Wessel E.

Micron. 2017 Oct;101:221-231. doi: 10.1016/j.micron.2017.07.010. Epub 2017 Jul 24.


Efficient Screening and Optimization of Membrane Protein Production in Escherichia coli.

Marino J, Holzhüter K, Kuhn B, Geertsma ER.

Methods Enzymol. 2017;594:139-164. doi: 10.1016/bs.mie.2017.05.011. Epub 2017 Jul 25.


Assessing recovery of stream insects from pesticides using a two-patch metapopulation model.

Schäfer RB, Kühn B, Hauer L, Kattwinkel M.

Sci Total Environ. 2017 Dec 31;609:788-798. doi: 10.1016/j.scitotenv.2017.07.222. Epub 2017 Jul 30.


Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy.

Roos J, Peters M, Maucher IV, Kühn B, Fettel J, Hellmuth N, Brat C, Sommer B, Urbschat A, Piesche M, Vogel A, Proschak E, Blöcher R, Buscató E, Häfner AK, Matrone C, Werz O, Heidler J, Wittig I, Angioni C, Geisslinger G, Parnham MJ, Zacharowski K, Steinhilber D, Maier TJ.

Antioxid Redox Signal. 2018 May 10;28(14):1265-1285. doi: 10.1089/ars.2017.7155. Epub 2017 Sep 8.


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