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Items: 27

1.

RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues.

Yizhak K, Aguet F, Kim J, Hess JM, Kübler K, Grimsby J, Frazer R, Zhang H, Haradhvala NJ, Rosebrock D, Livitz D, Li X, Arich-Landkof E, Shoresh N, Stewart C, Segrè AV, Branton PA, Polak P, Ardlie KG, Getz G.

Science. 2019 Jun 7;364(6444). pii: eaaw0726. doi: 10.1126/science.aaw0726.

PMID:
31171663
2.

Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma.

Gopal RK, Kübler K, Calvo SE, Polak P, Livitz D, Rosebrock D, Sadow PM, Campbell B, Donovan SE, Amin S, Gigliotti BJ, Grabarek Z, Hess JM, Stewart C, Braunstein LZ, Arndt PF, Mordecai S, Shih AR, Chaves F, Zhan T, Lubitz CC, Kim J, Iafrate AJ, Wirth L, Parangi S, Leshchiner I, Daniels GH, Mootha VK, Dias-Santagata D, Getz G, McFadden DG.

Cancer Cell. 2018 Aug 13;34(2):242-255.e5. doi: 10.1016/j.ccell.2018.06.013.

3.

Tumoral PD-L1 expression defines a subgroup of poor-prognosis vulvar carcinomas with non-viral etiology.

Hecking T, Thiesler T, Schiller C, Lunkenheimer JM, Ayub TH, Rohr A, Condic M, Keyver-Paik MD, Fimmers R, Kirfel J, Kuhn W, Kristiansen G, Kübler K.

Oncotarget. 2017 Oct 6;8(54):92890-92903. doi: 10.18632/oncotarget.21641. eCollection 2017 Nov 3.

4.

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer.

Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, Zick A, Orthwein A, Lawrence MS, Batra RN, Caldas C, Haber DA, Laird PW, Shen H, Ellisen LW, D'Andrea AD, Chanock SJ, Foulkes WD, Getz G.

Nat Genet. 2017 Oct;49(10):1476-1486. doi: 10.1038/ng.3934. Epub 2017 Aug 21.

PMID:
28825726
5.

Individual management of cervical cancer in pregnancy.

Hecking T, Abramian A, Domröse C, Engeln T, Thiesler T, Leutner C, Gembruch U, Keyver-Paik MD, Kuhn W, Kübler K.

Arch Gynecol Obstet. 2016 May;293(5):931-9. doi: 10.1007/s00404-015-3980-y. Epub 2016 Jan 4. Review.

6.

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA.

Herzner AM, Hagmann CA, Goldeck M, Wolter S, Kübler K, Wittmann S, Gramberg T, Andreeva L, Hopfner KP, Mertens C, Zillinger T, Jin T, Xiao TS, Bartok E, Coch C, Ackermann D, Hornung V, Ludwig J, Barchet W, Hartmann G, Schlee M.

Nat Immunol. 2015 Oct;16(10):1025-33. doi: 10.1038/ni.3267. Epub 2015 Sep 7.

7.

Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer.

Ayub TH, Keyver-Paik MD, Debald M, Rostamzadeh B, Thiesler T, Schröder L, Barchet W, Abramian A, Kaiser C, Kristiansen G, Kuhn W, Kübler K.

Oncotarget. 2015 Jun 30;6(18):16437-48.

8.

c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia.

Kübler K, Heinenberg S, Rudlowski C, Keyver-Paik MD, Abramian A, Merkelbach-Bruse S, Büttner R, Kuhn W, Schildhaus HU.

Oncotarget. 2015 Jan 20;6(2):825-35.

9.

Prognostic significance of tumor-associated macrophages in endometrial adenocarcinoma.

Kübler K, Ayub TH, Weber SK, Zivanovic O, Abramian A, Keyver-Paik MD, Mallmann MR, Kaiser C, Serçe NB, Kuhn W, Rudlowski C.

Gynecol Oncol. 2014 Nov;135(2):176-83. doi: 10.1016/j.ygyno.2014.08.028. Epub 2014 Aug 27.

PMID:
25173585
10.

Interval debulking surgery in patients with Federation of Gynecology and Obstetrics (FIGO) stage IIIC and IV ovarian cancer.

Keyver-Paik MD, Zivanovic O, Rudlowski C, Höller T, Wolfgarten M, Kübler K, Schröder L, Mallmann MR, Pölcher M, Kuhn W.

Onkologie. 2013;36(6):324-32. doi: 10.1159/000351256. Epub 2013 May 21. Erratum in: Onkologie. 2013;36(10):576. Mallmann, Michael [corrected to Mallmann, Michael R].

11.

Cardiorenal syndrome is present in human fetuses with severe, isolated urinary tract malformations.

Merz WM, Kübler K, Fimmers R, Willruth A, Stoffel-Wagner B, Gembruch U.

PLoS One. 2013 May 22;8(5):e63664. doi: 10.1371/journal.pone.0063664. Print 2013.

12.

Circulating N-terminal pro-B-type natriuretic peptide in fetal anemia before and after treatment.

Merz WM, Kübler K, Fimmers R, Stoffel-Wagner B, Geipel A, Gembruch U.

Pediatr Res. 2012 Aug;72(2):174-8.

PMID:
22546865
13.

N-terminal pro-B-type natriuretic peptide in the circulation of fetuses with cardiac malformations.

Merz WM, Kübler K, Albers E, Stoffel-Wagner B, Gembruch U.

Clin Res Cardiol. 2012 Feb;101(2):73-9. doi: 10.1007/s00392-011-0366-4. Epub 2011 Sep 29.

PMID:
21960417
14.

Immunogenic cell death of human ovarian cancer cells induced by cytosolic poly(I:C) leads to myeloid cell maturation and activates NK cells.

Kübler K, tho Pesch C, Gehrke N, Riemann S, Dassler J, Coch C, Landsberg J, Wimmenauer V, Pölcher M, Rudlowski C, Tüting T, Kuhn W, Hartmann G, Barchet W.

Eur J Immunol. 2011 Oct;41(10):3028-39. doi: 10.1002/eji.201141555. Epub 2011 Aug 30.

15.

Targeted activation of RNA helicase retinoic acid-inducible gene-I induces proimmunogenic apoptosis of human ovarian cancer cells.

Kübler K, Gehrke N, Riemann S, Böhnert V, Zillinger T, Hartmann E, Pölcher M, Rudlowski C, Kuhn W, Hartmann G, Barchet W.

Cancer Res. 2010 Jul 1;70(13):5293-304. doi: 10.1158/0008-5472.CAN-10-0825. Epub 2010 Jun 15.

16.

Changes in Ki-67 labeling indices during neoadjuvant chemotherapy for advanced ovarian cancer are associated with survival.

Pölcher M, Friedrichs N, Rudlowski C, Fimmers R, Keyver-Paik MD, Kübler K, Sauerwald A, Büttner R, Kuhn W, Braun M.

Int J Gynecol Cancer. 2010 May;20(4):555-60. doi: 10.1111/IGC.0b013e3181c104c0.

PMID:
20442588
17.

In vivo intratumor angiogenic treatment effects during taxane-based neoadjuvant chemotherapy of ovarian cancer.

Pölcher M, Rudlowski C, Friedrichs N, Mielich M, Höller T, Wolfgarten M, Kübler K, Büttner R, Kuhn W, Braun M.

BMC Cancer. 2010 Apr 13;10:137. doi: 10.1186/1471-2407-10-137.

18.

Sorafenib in combination with carboplatin and paclitaxel as neoadjuvant chemotherapy in patients with advanced ovarian cancer.

Pölcher M, Eckhardt M, Coch C, Wolfgarten M, Kübler K, Hartmann G, Kuhn W, Rudlowski C.

Cancer Chemother Pharmacol. 2010 May;66(1):203-7. doi: 10.1007/s00280-010-1276-2. Epub 2010 Mar 5.

PMID:
20204367
19.

Foxp3(+) cell infiltration and granzyme B(+)/Foxp3(+) cell ratio are associated with outcome in neoadjuvant chemotherapy-treated ovarian carcinoma.

Pölcher M, Braun M, Friedrichs N, Rudlowski C, Bercht E, Fimmers R, Sauerwald A, Keyver-Paik MD, Kübler K, Büttner R, Kuhn WC, Hernando JJ.

Cancer Immunol Immunother. 2010 Jun;59(6):909-19. doi: 10.1007/s00262-010-0817-1. Epub 2010 Jan 20.

PMID:
20087581
20.

Reference values for N-terminal pro-B-type natriuretic peptide in fetal circulation between 20 and 34 weeks of gestation.

Merz WM, Kübler K, Albers E, Stoffel-Wagner B, Gembruch U.

Clin Biochem. 2010 Mar;43(4-5):519-21. doi: 10.1016/j.clinbiochem.2009.11.012. Epub 2009 Dec 5.

PMID:
19968983
21.

Interactive effects of sulfur and nitrogen supply on the concentration of sinigrin and allyl isothiocyanate in Indian mustard (Brassica juncea L.).

Gerendás J, Podestát J, Stahl T, Kübler K, Brückner H, Mersch-Sundermann V, Mühling KH.

J Agric Food Chem. 2009 May 13;57(9):3837-44. doi: 10.1021/jf803636h.

PMID:
19309148
22.

High-risk pregnancy management in women with hypopituitarism.

Kübler K, Klingmüller D, Gembruch U, Merz WM.

J Perinatol. 2009 Feb;29(2):89-95. doi: 10.1038/jp.2008.116. Review.

PMID:
19177043
23.

Genetic alterations of HLA-class II in ovarian cancer.

Kübler K, Arndt PF, Wardelmann E, Landwehr C, Krebs D, Kuhn W, van der Ven K.

Int J Cancer. 2008 Sep 15;123(6):1350-6. doi: 10.1002/ijc.23624.

24.

HLA-class II haplotype associations with ovarian cancer.

Kübler K, Arndt PF, Wardelmann E, Krebs D, Kuhn W, van der Ven K.

Int J Cancer. 2006 Dec 15;119(12):2980-5.

25.

Oxytocin receptor gene expression of estrogen-stimulated human myometrium in extracorporeally perfused non-pregnant uteri.

Richter ON, Kübler K, Schmolling J, Kupka M, Reinsberg J, Ulrich U, van der Ven H, Wardelmann E, van der Ven K.

Mol Hum Reprod. 2004 May;10(5):339-46. Epub 2004 Mar 25.

PMID:
15044599
26.

Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: clinical and immunological evaluation of a phase I trial.

Hernando JJ, Park TW, Kübler K, Offergeld R, Schlebusch H, Bauknecht T.

Cancer Immunol Immunother. 2002 Mar;51(1):45-52. Epub 2002 Jan 10.

PMID:
11845259
27.

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