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Best matches for Küblbeck J[au]:

An update on the constitutive androstane receptor (CAR). Molnár F et al. Drug Metabol Drug Interact. (2013)

Genetically Modified Caco-2 Cells With Improved Cytochrome P450 Metabolic Capacity. Küblbeck J et al. J Pharm Sci. (2016)

Improved assays for xenosensor activation based on reverse transfection. Küblbeck J et al. Toxicol In Vitro. (2015)

Search results

Items: 21

1.

The Basis for Strain-Dependent Rat Aldehyde Dehydrogenase 1A7 (ALDH1A7) Gene Expression.

Touloupi K, Küblbeck J, Magklara A, Molnár F, Reinisalo M, Konstandi M, Honkakoski P, Pappas P.

Mol Pharmacol. 2019 Nov;96(5):655-663. doi: 10.1124/mol.119.117424. Epub 2019 Oct 1.

PMID:
31575620
2.

Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin.

Orlik C, Deibel D, Küblbeck J, Balta E, Ganskih S, Habicht J, Niesler B, Schröder-Braunstein J, Schäkel K, Wabnitz G, Samstag Y.

Cell Mol Immunol. 2019 Jul 19. doi: 10.1038/s41423-019-0261-x. [Epub ahead of print]

PMID:
31324882
3.

A Reverse Transfection Method for Screening of Nuclear Receptor Activators.

Küblbeck J, Honkakoski P.

Methods Mol Biol. 2019;1966:163-173. doi: 10.1007/978-1-4939-9195-2_13.

PMID:
31041746
4.

DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene.

Giantin M, Küblbeck J, Zancanella V, Prantner V, Sansonetti F, Schoeniger A, Tolosi R, Guerra G, Da Ros S, Dacasto M, Honkakoski P.

PLoS One. 2019 Mar 25;14(3):e0214338. doi: 10.1371/journal.pone.0214338. eCollection 2019.

5.

Metabolism of Scoparone in Experimental Animals and Humans.

Juvonen RO, Novák F, Emmanouilidou E, Auriola S, Timonen J, Heikkinen AT, Küblbeck J, Finel M, Raunio H.

Planta Med. 2019 Apr;85(6):453-464. doi: 10.1055/a-0835-2301. Epub 2019 Feb 8.

PMID:
30736072
6.

Regulation of Human Pluripotent Stem Cell-Derived Hepatic Cell Phenotype by Three-Dimensional Hydrogel Models.

Toivonen S, Malinen MM, Küblbeck J, Petsalo A, Urtti A, Honkakoski P, Otonkoski T.

Tissue Eng Part A. 2016 Jul;22(13-14):971-84. doi: 10.1089/ten.TEA.2016.0127. Epub 2016 Jul 7.

PMID:
27329070
7.

Genetically Modified Caco-2 Cells With Improved Cytochrome P450 Metabolic Capacity.

Küblbeck J, Hakkarainen JJ, Petsalo A, Vellonen KS, Tolonen A, Reponen P, Forsberg MM, Honkakoski P.

J Pharm Sci. 2016 Feb;105(2):941-949. doi: 10.1016/S0022-3549(15)00187-2.

PMID:
26869438
8.

Improved assays for xenosensor activation based on reverse transfection.

Küblbeck J, Anttila T, Pulkkinen JT, Honkakoski P.

Toxicol In Vitro. 2015 Oct;29(7):1759-65. doi: 10.1016/j.tiv.2015.07.011. Epub 2015 Jul 14.

PMID:
26187274
9.

Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.

Küblbeck J, Zancanella V, Prantner V, Molnár F, Squires EJ, Dacasto M, Honkakoski P, Giantin M.

Xenobiotica. 2016;46(3):200-10. doi: 10.3109/00498254.2015.1060374. Epub 2015 Jul 7.

PMID:
26153444
10.

Direct and rapid transcript analysis assay for CYP mRNA expression and inducibility in human primary hepatocytes.

Mattinen L, Kublbeck J, Rechardt O, Honkakoski P, Rautio J.

Drug Metab Lett. 2014;8(2):77-87.

PMID:
24910238
11.

Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator.

Poutiainen PK, Huhtala T, Jääskeläinen T, Petsalo A, Küblbeck J, Kaikkonen S, Palvimo JJ, Raunio H, Närvänen A, Peräkylä M, Juvonen RO, Honkakoski P, Laatikainen R, Pulkkinen JT.

Mol Cell Endocrinol. 2014 Apr 25;387(1-2):8-18. doi: 10.1016/j.mce.2014.02.008. Epub 2014 Feb 22.

PMID:
24565895
12.

Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system.

Pimkaew P, Küblbeck J, Petsalo A, Jukka J, Suksamrarn A, Juvonen R, Auriola S, Piyachaturawat P, Honkakoski P.

Toxicol In Vitro. 2013 Sep;27(6):2005-12. doi: 10.1016/j.tiv.2013.07.004. Epub 2013 Jul 12.

PMID:
23850985
13.

An update on the constitutive androstane receptor (CAR).

Molnár F, Küblbeck J, Jyrkkärinne J, Prantner V, Honkakoski P.

Drug Metabol Drug Interact. 2013;28(2):79-93. doi: 10.1515/dmdi-2013-0009. Review.

PMID:
23729557
14.

Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system.

Ma L, Barker J, Zhou C, Li W, Zhang J, Lin B, Foltz G, Küblbeck J, Honkakoski P.

Biomaterials. 2012 Jun;33(17):4353-61. doi: 10.1016/j.biomaterials.2012.02.054. Epub 2012 Mar 18.

15.

Characterization of human cytochrome P450 induction by pesticides.

Abass K, Lämsä V, Reponen P, Küblbeck J, Honkakoski P, Mattila S, Pelkonen O, Hakkola J.

Toxicology. 2012 Mar 29;294(1):17-26. doi: 10.1016/j.tox.2012.01.010. Epub 2012 Jan 28.

PMID:
22310298
16.

Molecular dynamics simulations for human CAR inverse agonists.

Jyrkkärinne J, Küblbeck J, Pulkkinen J, Honkakoski P, Laatikainen R, Poso A, Laitinen T.

J Chem Inf Model. 2012 Feb 27;52(2):457-64. doi: 10.1021/ci200432k. Epub 2012 Jan 25.

PMID:
22233089
17.

New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists.

Küblbeck J, Jyrkkärinne J, Molnár F, Kuningas T, Patel J, Windshügel B, Nevalainen T, Laitinen T, Sippl W, Poso A, Honkakoski P.

Mol Pharm. 2011 Dec 5;8(6):2424-33. doi: 10.1021/mp2003658. Epub 2011 Nov 1.

PMID:
22044162
18.

Use of comprehensive screening methods to detect selective human CAR activators.

Küblbeck J, Laitinen T, Jyrkkärinne J, Rousu T, Tolonen A, Abel T, Kortelainen T, Uusitalo J, Korjamo T, Honkakoski P, Molnár F.

Biochem Pharmacol. 2011 Dec 15;82(12):1994-2007. doi: 10.1016/j.bcp.2011.08.027. Epub 2011 Sep 8.

PMID:
21924250
19.

Up-regulation of CYP expression in hepatoma cells stably transfected by chimeric nuclear receptors.

Küblbeck J, Reinisalo M, Mustonen R, Honkakoski P.

Eur J Pharm Sci. 2010 Jul 11;40(4):263-72. doi: 10.1016/j.ejps.2010.03.022. Epub 2010 Apr 8.

PMID:
20381613
20.

Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship.

Jyrkkärinne J, Windshügel B, Rönkkö T, Tervo AJ, Küblbeck J, Lahtela-Kakkonen M, Sippl W, Poso A, Honkakoski P.

J Med Chem. 2008 Nov 27;51(22):7181-92. doi: 10.1021/jm800731b.

PMID:
18983136
21.

Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor.

Küblbeck J, Jyrkkärinne J, Poso A, Turpeinen M, Sippl W, Honkakoski P, Windshügel B.

Biochem Pharmacol. 2008 Nov 15;76(10):1288-97. doi: 10.1016/j.bcp.2008.08.014. Epub 2008 Aug 22.

PMID:
18786510

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