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Best matches for Kötting C[au]:

Common mechanisms of catalysis in small and heterotrimeric GTPases and their respective GAPs. Gerwert K et al. Biol Chem. (2017)

What vibrations tell us about GTPases. Kötting C et al. Biol Chem. (2015)

Virtual staining of colon cancer tissue by label-free Raman micro-spectroscopy. Petersen D et al. Analyst. (2017)

Search results

Items: 1 to 50 of 58

1.

GTP Hydrolysis Without an Active Site Base: A Unifying Mechanism for Ras and Related GTPases.

Calixto AR, Moreira C, Pabis A, Kötting C, Gerwert K, Rudack T, Kamerlin SCL.

J Am Chem Soc. 2019 Jun 14. doi: 10.1021/jacs.9b03193. [Epub ahead of print]

PMID:
31199130
2.

Monitoring transient events in infrared spectra using local mode analysis.

Massarczyk M, Schlitter J, Kötting C, Rudack T, Gerwert K.

Proteins. 2018 Oct;86(10):1013-1019. doi: 10.1002/prot.25536. Epub 2018 Oct 29.

PMID:
30019772
3.

Ligand-Induced Conformational Changes in HSP90 Monitored Time Resolved and Label Free-Towards a Conformational Activity Screening for Drug Discovery.

Güldenhaupt J, Amaral M, Kötting C, Schartner J, Musil D, Frech M, Gerwert K.

Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9955-9960. doi: 10.1002/anie.201802603. Epub 2018 Jul 3.

4.

Highly stable protein immobilization via maleimido-thiol chemistry to monitor enzymatic activity.

Schartner J, Güldenhaupt J, Katharina Gaßmeyer S, Rosga K, Kourist R, Gerwert K, Kötting C.

Analyst. 2018 May 15;143(10):2276-2284. doi: 10.1039/c8an00301g.

PMID:
29708245
5.

Label-free identification of myopathological features with coherent anti-Stokes Raman scattering.

Niedieker D, GrosserÜschkamp F, Schreiner A, Barkovits K, Kötting C, Marcus K, Gerwert K, Vorgerd M.

Muscle Nerve. 2018 Sep;58(3):456-459. doi: 10.1002/mus.26140. Epub 2018 May 17.

PMID:
29663456
6.

Raman Microspectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells.

Aljakouch K, Lechtonen T, Yosef HK, Hammoud MK, Alsaidi W, Kötting C, Mügge C, Kourist R, El-Mashtoly SF, Gerwert K.

Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7250-7254. doi: 10.1002/anie.201803394. Epub 2018 May 16.

7.

Specific Substates of Ras To Interact with GAPs and Effectors: Revealed by Theoretical Simulations and FTIR Experiments.

Li Y, Zhang Y, Großerüschkamp F, Stephan S, Cui Q, Kötting C, Xia F, Gerwert K.

J Phys Chem Lett. 2018 Mar 15;9(6):1312-1317. doi: 10.1021/acs.jpclett.8b00342. Epub 2018 Mar 2.

PMID:
29488771
8.

The protonation states of GTP and GppNHp in Ras proteins.

Mann D, Güldenhaupt J, Schartner J, Gerwert K, Kötting C.

J Biol Chem. 2018 Mar 16;293(11):3871-3879. doi: 10.1074/jbc.RA117.001110. Epub 2018 Jan 30.

9.

An ATR-FTIR Sensor Unraveling the Drug Intervention of Methylene Blue, Congo Red, and Berberine on Human Tau and Aβ.

Schartner J, Nabers A, Budde B, Lange J, Hoeck N, Wiltfang J, Kötting C, Gerwert K.

ACS Med Chem Lett. 2017 Jun 11;8(7):710-714. doi: 10.1021/acsmedchemlett.7b00079. eCollection 2017 Jul 13.

10.

Raman fiber-optical method for colon cancer detection: Cross-validation and outlier identification approach.

Petersen D, Naveed P, Ragheb A, Niedieker D, El-Mashtoly SF, Brechmann T, Kötting C, Schmiegel WH, Freier E, Pox C, Gerwert K.

Spectrochim Acta A Mol Biomol Spectrosc. 2017 Jun 15;181:270-275. doi: 10.1016/j.saa.2017.03.054. Epub 2017 Mar 25.

PMID:
28384603
11.

Common mechanisms of catalysis in small and heterotrimeric GTPases and their respective GAPs.

Gerwert K, Mann D, Kötting C.

Biol Chem. 2017 May 1;398(5-6):523-533. doi: 10.1515/hsz-2016-0314. Review.

PMID:
28245182
12.

Local Mode Analysis: Decoding IR Spectra by Visualizing Molecular Details.

Massarczyk M, Rudack T, Schlitter J, Kuhne J, Kötting C, Gerwert K.

J Phys Chem B. 2017 Apr 20;121(15):3483-3492. doi: 10.1021/acs.jpcb.6b09343. Epub 2017 Feb 8.

PMID:
28092441
13.

Elucidation of Single Hydrogen Bonds in GTPases via Experimental and Theoretical Infrared Spectroscopy.

Mann D, Höweler U, Kötting C, Gerwert K.

Biophys J. 2017 Jan 10;112(1):66-77. doi: 10.1016/j.bpj.2016.11.3195.

14.

Mechanism of the intrinsic arginine finger in heterotrimeric G proteins.

Mann D, Teuber C, Tennigkeit SA, Schröter G, Gerwert K, Kötting C.

Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8041-E8050. Epub 2016 Nov 28.

15.

Virtual staining of colon cancer tissue by label-free Raman micro-spectroscopy.

Petersen D, Mavarani L, Niedieker D, Freier E, Tannapfel A, Kötting C, Gerwert K, El-Mashtoly SF.

Analyst. 2017 Apr 10;142(8):1207-1215. doi: 10.1039/c6an02072k.

PMID:
27840868
16.

Unraveling the Phosphocholination Mechanism of the Legionella pneumophila Enzyme AnkX.

Gavriljuk K, Schartner J, Seidel H, Dickhut C, Zahedi RP, Hedberg C, Kötting C, Gerwert K.

Biochemistry. 2016 Aug 9;55(31):4375-85. doi: 10.1021/acs.biochem.6b00524. Epub 2016 Jul 27.

PMID:
27404583
17.

Amyloid-β-Secondary Structure Distribution in Cerebrospinal Fluid and Blood Measured by an Immuno-Infrared-Sensor: A Biomarker Candidate for Alzheimer's Disease.

Nabers A, Ollesch J, Schartner J, Kötting C, Genius J, Hafermann H, Klafki H, Gerwert K, Wiltfang J.

Anal Chem. 2016 Mar 1;88(5):2755-62. doi: 10.1021/acs.analchem.5b04286. Epub 2016 Feb 16.

PMID:
26828829
18.

Catalysis of GTP hydrolysis by small GTPases at atomic detail by integration of X-ray crystallography, experimental, and theoretical IR spectroscopy.

Rudack T, Jenrich S, Brucker S, Vetter IR, Gerwert K, Kötting C.

J Biol Chem. 2015 Oct 2;290(40):24079-90. doi: 10.1074/jbc.M115.648071. Epub 2015 Aug 13.

19.

Chemical Functionalization of Germanium with Dextran Brushes for Immobilization of Proteins Revealed by Attenuated Total Reflection Fourier Transform Infrared Difference Spectroscopy.

Schartner J, Hoeck N, Güldenhaupt J, Mavarani L, Nabers A, Gerwert K, Kötting C.

Anal Chem. 2015 Jul 21;87(14):7467-75. doi: 10.1021/acs.analchem.5b01823. Epub 2015 Jul 8.

PMID:
26102158
20.

Label-Free Raman Spectroscopic Imaging Monitors the Integral Physiologically Relevant Drug Responses in Cancer Cells.

El-Mashtoly SF, Yosef HK, Petersen D, Mavarani L, Maghnouj A, Hahn S, Kötting C, Gerwert K.

Anal Chem. 2015 Jul 21;87(14):7297-304. doi: 10.1021/acs.analchem.5b01431. Epub 2015 Jun 26.

PMID:
26075314
21.
22.

An infrared sensor analysing label-free the secondary structure of the Abeta peptide in presence of complex fluids.

Nabers A, Ollesch J, Schartner J, Kötting C, Genius J, Haußmann U, Klafki H, Wiltfang J, Gerwert K.

J Biophotonics. 2016 Mar;9(3):224-34. doi: 10.1002/jbio.201400145. Epub 2015 Mar 23.

PMID:
25808829
23.

Immobilization of proteins in their physiological active state at functionalized thiol monolayers on ATR-germanium crystals.

Schartner J, Gavriljuk K, Nabers A, Weide P, Muhler M, Gerwert K, Kötting C.

Chembiochem. 2014 Nov 24;15(17):2529-34. doi: 10.1002/cbic.201402478. Epub 2014 Sep 24.

PMID:
25256748
24.

What vibrations tell us about GTPases.

Kötting C, Gerwert K.

Biol Chem. 2015 Feb;396(2):131-44. doi: 10.1515/hsz-2014-0219. Review.

PMID:
25153240
25.
26.

Reaction mechanism of adenylyltransferase DrrA from Legionella pneumophila elucidated by time-resolved fourier transform infrared spectroscopy.

Gavriljuk K, Schartner J, Itzen A, Goody RS, Gerwert K, Kötting C.

J Am Chem Soc. 2014 Jul 2;136(26):9338-45. doi: 10.1021/ja501496d. Epub 2014 Jun 20.

PMID:
24950229
27.

Automated identification of subcellular organelles by coherent anti-stokes Raman scattering.

El-Mashtoly SF, Niedieker D, Petersen D, Krauss SD, Freier E, Maghnouj A, Mosig A, Hahn S, Kötting C, Gerwert K.

Biophys J. 2014 May 6;106(9):1910-20. doi: 10.1016/j.bpj.2014.03.025.

28.

Label-free imaging of drug distribution and metabolism in colon cancer cells by Raman microscopy.

El-Mashtoly SF, Petersen D, Yosef HK, Mosig A, Reinacher-Schick A, Kötting C, Gerwert K.

Analyst. 2014 Mar 7;139(5):1155-61. doi: 10.1039/c3an01993d. Epub 2014 Jan 15.

PMID:
24427772
29.

Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy.

Gavriljuk K, Itzen A, Goody RS, Gerwert K, Kötting C.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13380-5. doi: 10.1073/pnas.1307655110. Epub 2013 Jul 29.

30.

Spectral histopathology of colon cancer tissue sections by Raman imaging with 532 nm excitation provides label free annotation of lymphocytes, erythrocytes and proliferating nuclei of cancer cells.

Mavarani L, Petersen D, El-Mashtoly SF, Mosig A, Tannapfel A, Kötting C, Gerwert K.

Analyst. 2013 Jul 21;138(14):4035-9. doi: 10.1039/c3an00370a. Epub 2013 Jun 4.

PMID:
23733134
31.

Monitoring protein-ligand interactions by time-resolved FTIR difference spectroscopy.

Kötting C, Gerwert K.

Methods Mol Biol. 2013;1008:299-323. doi: 10.1007/978-1-62703-398-5_11.

PMID:
23729257
32.

The dynamics of the catalytic site in small GTPases, variations on a common motif.

Kötting C, Gerwert K.

FEBS Lett. 2013 Jun 27;587(13):2025-7. doi: 10.1016/j.febslet.2013.05.021. Epub 2013 May 16. Review.

33.

Universal method for protein immobilization on chemically functionalized germanium investigated by ATR-FTIR difference spectroscopy.

Schartner J, Güldenhaupt J, Mei B, Rögner M, Muhler M, Gerwert K, Kötting C.

J Am Chem Soc. 2013 Mar 13;135(10):4079-87. doi: 10.1021/ja400253p. Epub 2013 Mar 4.

PMID:
23414555
34.

Catalytic mechanism of a mammalian Rab·RabGAP complex in atomic detail.

Gavriljuk K, Gazdag EM, Itzen A, Kötting C, Goody RS, Gerwert K.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21348-53. doi: 10.1073/pnas.1214431110. Epub 2012 Dec 12.

35.

Detailed structure of the H2PO4(-)-guanosine diphosphate intermediate in Ras-GAP decoded from FTIR experiments by biomolecular simulations.

Xia F, Rudack T, Cui Q, Kötting C, Gerwert K.

J Am Chem Soc. 2012 Dec 12;134(49):20041-4. doi: 10.1021/ja310496e. Epub 2012 Dec 3.

PMID:
23181905
36.

N-Ras forms dimers at POPC membranes.

Güldenhaupt J, Rudack T, Bachler P, Mann D, Triola G, Waldmann H, Kötting C, Gerwert K.

Biophys J. 2012 Oct 3;103(7):1585-93. doi: 10.1016/j.bpj.2012.08.043. Epub 2012 Oct 2.

37.

Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations.

Rudack T, Xia F, Schlitter J, Kötting C, Gerwert K.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15295-300. Epub 2012 Sep 4.

38.

The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations.

Rudack T, Xia F, Schlitter J, Kötting C, Gerwert K.

Biophys J. 2012 Jul 18;103(2):293-302. doi: 10.1016/j.bpj.2012.06.015. Epub 2012 Jul 17.

39.

Surface-attached polyhistidine-tag proteins characterized by FTIR difference spectroscopy.

Pinkerneil P, Güldenhaupt J, Gerwert K, Kötting C.

Chemphyschem. 2012 Aug 6;13(11):2649-53. doi: 10.1002/cphc.201200358. Epub 2012 Jun 15.

40.

Time-resolved Fourier transform infrared spectroscopy of the nucleotide-binding domain from the ATP-binding Cassette transporter MsbA: ATP hydrolysis is the rate-limiting step in the catalytic cycle.

Syberg F, Suveyzdis Y, Kötting C, Gerwert K, Hofmann E.

J Biol Chem. 2012 Jul 6;287(28):23923-31. doi: 10.1074/jbc.M112.359208. Epub 2012 May 16.

41.

Heme oxygenases from Arabidopsis thaliana reveal different mechanisms of carbon monoxide binding.

Gisk B, Molitor B, Frankenberg-Dinkel N, Kötting C.

Spectrochim Acta A Mol Biomol Spectrosc. 2012 Mar;88:235-40. doi: 10.1016/j.saa.2011.12.011. Epub 2011 Dec 13.

PMID:
22204880
42.

The specific vibrational modes of GTP in solution and bound to Ras: a detailed theoretical analysis by QM/MM simulations.

Xia F, Rudack T, Kötting C, Schlitter J, Gerwert K.

Phys Chem Chem Phys. 2011 Dec 28;13(48):21451-60. doi: 10.1039/c1cp22741f. Epub 2011 Nov 2.

PMID:
22048726
43.

Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions.

Kötting C, Suveyzdis Y, Bojja RS, Metzler-Nolte N, Gerwert K.

Appl Spectrosc. 2010 Sep;64(9):967-72. doi: 10.1366/000370210792434341.

PMID:
20828432
44.

Tyr39 of ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis.

Brucker S, Gerwert K, Kötting C.

J Mol Biol. 2010 Aug 6;401(1):1-6. doi: 10.1016/j.jmb.2010.05.068. Epub 2010 Jun 2.

PMID:
20609434
45.

Unravelling the mechanism of dual-specificity GAPs.

Sot B, Kötting C, Deaconescu D, Suveyzdis Y, Gerwert K, Wittinghofer A.

EMBO J. 2010 Apr 7;29(7):1205-14. doi: 10.1038/emboj.2010.20. Epub 2010 Feb 25.

46.

Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter.

Völlmecke C, Kötting C, Gerwert K, Lübben M.

FEBS J. 2009 Nov;276(21):6172-86. doi: 10.1111/j.1742-4658.2009.07320.x. Epub 2009 Sep 22.

47.

Secondary structure of lipidated Ras bound to a lipid bilayer.

Güldenhaupt J, Adigüzel Y, Kuhlmann J, Waldmann H, Kötting C, Gerwert K.

FEBS J. 2008 Dec;275(23):5910-8. doi: 10.1111/j.1742-4658.2008.06720.x.

48.

The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy.

Kötting C, Kallenbach A, Suveyzdis Y, Wittinghofer A, Gerwert K.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6260-5. doi: 10.1073/pnas.0712095105. Epub 2008 Apr 23.

49.

Surface change of Ras enabling effector binding monitored in real time at atomic resolution.

Kötting C, Kallenbach A, Suveyzdis Y, Eichholz C, Gerwert K.

Chembiochem. 2007 May 7;8(7):781-7.

PMID:
17385754
50.

Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach.

Chakrabarti PP, Daumke O, Suveyzdis Y, Kötting C, Gerwert K, Wittinghofer A.

J Mol Biol. 2007 Apr 6;367(4):983-95. Epub 2006 Nov 10.

PMID:
17300802

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