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Items: 27


Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.

Espéli M, Clatworthy MR, Bökers S, Lawlor KE, Cutler AJ, Köntgen F, Lyons PA, Smith KG.

J Exp Med. 2012 Nov 19;209(12):2307-19. doi: 10.1084/jem.20121752. Epub 2012 Oct 29.


Renin enhancer is critical for control of renin gene expression and cardiovascular function.

Adams DJ, Head GA, Markus MA, Lovicu FJ, van der Weyden L, Köntgen F, Arends MJ, Thiru S, Mayorov DN, Morris BJ.

J Biol Chem. 2006 Oct 20;281(42):31753-61. Epub 2006 Aug 8. Erratum in: J Biol Chem. 2006 Dec 29;281(52):40527.


The phosphatidylserine receptor has essential functions during embryogenesis but not in apoptotic cell removal.

Böse J, Gruber AD, Helming L, Schiebe S, Wegener I, Hafner M, Beales M, Köntgen F, Lengeling A.

J Biol. 2004;3(4):15. Epub 2004 Aug 23.


Impaired cardiac contractility response to hemodynamic stress in S100A1-deficient mice.

Du XJ, Cole TJ, Tenis N, Gao XM, Köntgen F, Kemp BE, Heierhorst J.

Mol Cell Biol. 2002 Apr;22(8):2821-9.


Molecular cloning of F4/80-like-receptor, a seven-span membrane protein expressed differentially by dendritic cell and monocyte-macrophage subpopulations.

Caminschi I, Lucas KM, O'Keeffe MA, Hochrein H, Laâbi Y, Köntgen F, Lew AM, Shortman K, Wright MD.

J Immunol. 2001 Oct 1;167(7):3570-6.


Gene targeting in a centralized facility.

Barnett LD, Köntgen F.

Methods Mol Biol. 2001;158:65-82. Review. No abstract available.


Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity.

Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Köntgen F, Adams JM, Strasser A.

Science. 1999 Nov 26;286(5445):1735-8.


EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract.

Dottori M, Hartley L, Galea M, Paxinos G, Polizzotto M, Kilpatrick T, Bartlett PF, Murphy M, Köntgen F, Boyd AW.

Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13248-53.


Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant.

Print CG, Loveland KL, Gibson L, Meehan T, Stylianou A, Wreford N, de Kretser D, Metcalf D, Köntgen F, Adams JM, Cory S.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12424-31.


Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy.

Elefanty AG, Begley CG, Metcalf D, Barnett L, Köntgen F, Robb L.

Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11897-902.


Major histocompatibility complex class II expression by intrinsic renal cells is required for crescentic glomerulonephritis.

Li S, Kurts C, Köntgen F, Holdsworth SR, Tipping PG.

J Exp Med. 1998 Aug 3;188(3):597-602.


Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue.

Körner H, Cook M, Riminton DS, Lemckert FA, Hoek RM, Ledermann B, Köntgen F, Fazekas de St Groth B, Sedgwick JD.

Eur J Immunol. 1997 Oct;27(10):2600-9.


Adult mice with targeted mutation of the interleukin-11 receptor (IL11Ra) display normal hematopoiesis.

Nandurkar HH, Robb L, Tarlinton D, Barnett L, Köntgen F, Begley CG.

Blood. 1997 Sep 15;90(6):2148-59.


Homeosis and intestinal tumours in Cdx2 mutant mice.

Chawengsaksophak K, James R, Hammond VE, Köntgen F, Beck F.

Nature. 1997 Mar 6;386(6620):84-7.


The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse.

Robb L, Elwood NJ, Elefanty AG, Köntgen F, Li R, Barnett LD, Begley CG.

EMBO J. 1996 Aug 15;15(16):4123-9.


Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice.

Haziot A, Ferrero E, Köntgen F, Hijiya N, Yamamoto S, Silver J, Stewart CL, Goyert SM.

Immunity. 1996 Apr;4(4):407-14.


Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

Köntgen F, Grumont RJ, Strasser A, Metcalf D, Li R, Tarlinton D, Gerondakis S.

Genes Dev. 1995 Aug 15;9(16):1965-77.


Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.

Robb L, Lyons I, Li R, Hartley L, Köntgen F, Harvey RP, Metcalf D, Begley CG.

Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):7075-9.


Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes.

Lundberg K, Heath W, Köntgen F, Carbone FR, Shortman K.

J Exp Med. 1995 May 1;181(5):1643-51.


Creation and characterization of E-selectin- and VCAM-1-deficient mice.

Kwee L, Burns DK, Rumberger JM, Norton C, Wolitzky B, Terry R, Lombard-Gillooly KM, Shuster DJ, Kontgen F, Stewart C, et al.

Ciba Found Symp. 1995;189:17-28; discussion 28-34, 77-8. Review.


T cell development in mice lacking the CD3-zeta/eta gene.

Malissen M, Gillet A, Rocha B, Trucy J, Vivier E, Boyer C, Köntgen F, Brun N, Mazza G, Spanopoulou E, et al.

EMBO J. 1993 Nov;12(11):4347-55.


Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes.

Rothe J, Lesslauer W, Lötscher H, Lang Y, Koebel P, Köntgen F, Althage A, Zinkernagel R, Steinmetz M, Bluethmann H.

Nature. 1993 Aug 26;364(6440):798-802.


Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.

Köntgen F, Süss G, Stewart C, Steinmetz M, Bluethmann H.

Int Immunol. 1993 Aug;5(8):957-64.


Simple screening procedure to detect gene targeting events in embryonic stem cells.

Köntgen F, Stewart CL.

Methods Enzymol. 1993;225:878-90. No abstract available.


Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor.

Stewart CL, Kaspar P, Brunet LJ, Bhatt H, Gadi I, Köntgen F, Abbondanzo SJ.

Nature. 1992 Sep 3;359(6390):76-9.


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