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TRThe Expression of Aldolase B in Islets is Negatively Associated with Insulin Secretion in Humans.

Gerst F, Jaghutriz BA, Staiger H, Schulte AM, Lorza-Gil E, Kaiser G, Panse M, Haug S, Heni M, Schütz M, Stadion M, Schürmann A, Marzetta F, Ibberson M, Sipos B, Fend F, Fleming T, Nawroth PP, Königsrainer A, Nadalin S, Wagner S, Peter A, Fritsche A, Richter D, Solimena M, Häring HU, Ullrich S, Wagner R.

J Clin Endocrinol Metab. 2018 Sep 7. doi: 10.1210/jc.2018-00791. [Epub ahead of print]


cGMP-dependent protein kinase I (cGKI) modulates human hepatic stellate cell activation.

Franko A, Kovarova M, Feil S, Feil R, Wagner R, Heni M, Königsrainer A, Ruoß M, Nüssler AK, Weigert C, Häring HU, Lutz SZ, Peter A.

Metabolism. 2018 Sep 6. pii: S0026-0495(18)30175-6. doi: 10.1016/j.metabol.2018.09.001. [Epub ahead of print]


Perioperative Systemic Chemotherapy, Cytoreductive Surgery, and Hyperthermic Intraperitoneal Chemotherapy in Patients With Colorectal Peritoneal Metastasis: Results of the Prospective Multicenter Phase 2 COMBATAC Trial.

Glockzin G, Zeman F, Croner RS, Königsrainer A, Pelz J, Ströhlein MA, Rau B, Arnold D, Koller M, Schlitt HJ, Piso P.

Clin Colorectal Cancer. 2018 Jul 31. pii: S1533-0028(18)30223-8. doi: 10.1016/j.clcc.2018.07.011. [Epub ahead of print]


First case report of malignant peritoneal mesothelioma and oral verrucous carcinoma in a patient with a germline PTEN mutation: a combination of extremely rare diseases with probable further implications.

Löffler MW, Steinhilber J, Hilke FJ, Haen SP, Bösmüller H, Montes-Mojarro IA, Bonzheim I, Stäbler A, Faust U, Grasshoff U, Königsrainer I, Rammensee HG, Kanz L, Königsrainer A, Beckert S, Riess O, Schroeder C.

BMC Med Genet. 2018 Aug 15;19(1):144. doi: 10.1186/s12881-018-0651-4.


Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastases of pancreas and biliary tract cancer.

Horvath P, Beckert S, Struller F, Königsrainer A, Reymond MA.

Clin Exp Metastasis. 2018 Jul 30. doi: 10.1007/s10585-018-9925-7. [Epub ahead of print]


Chemosensitivity of various peritoneal cancer cell lines to HIPEC and PIPAC: comparison of an experimental duplex drug to standard drug regimens in vitro.

Weinreich J, Struller F, Sautkin I, Giuashvili S, Reymond M, Königsrainer A, Schott TC.

Invest New Drugs. 2018 Jul 18. doi: 10.1007/s10637-018-0641-6. [Epub ahead of print]


Multimodal Treatment Strategies for Esophageal Perforation.

Horvath P, Lange J, Stüker D, Wichmann D, Hilbert J, Götz M, Königsrainer A, von Feilitzsch M, Zdichavsky M.

Surg Laparosc Endosc Percutan Tech. 2018 Aug;28(4):232-238. doi: 10.1097/SLE.0000000000000549.


[Surgical treatment of peritoneal metastases from gynecological primary tumors].

Horvath P, Königsrainer A.

Chirurg. 2018 Sep;89(9):678-686. doi: 10.1007/s00104-018-0679-1. Review. German.


Automated closed-loop management of body temperature using forced-air blankets: preliminary feasibility study in a porcine model.

Peter J, Klingert K, Klingert W, Thiel K, Königsrainer A, Grasshoff C, Rosenstiel W, Schenk M.

BMC Anesthesiol. 2018 Jul 3;18(1):80. doi: 10.1186/s12871-018-0542-4.


Paradigm Shift in the Management of Irresectable Colorectal Liver Metastases: Living Donor Auxiliary Partial Orthotopic Liver Transplantation in Combination With Two-stage Hepatectomy (LD-RAPID).

Königsrainer A, Templin S, Capobianco I, Königsrainer I, Bitzer M, Zender L, Sipos B, Kanz L, Wagner S, Nadalin S.

Ann Surg. 2018 Jun 18. doi: 10.1097/SLA.0000000000002861. [Epub ahead of print]


Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation.

Löffler MW, Kowalewski DJ, Backert L, Bernhardt J, Adam P, Schuster H, Dengler F, Backes D, Kopp HG, Beckert S, Wagner S, Königsrainer I, Kohlbacher O, Kanz L, Königsrainer A, Rammensee HG, Stevanović S, Haen SP.

Cancer Res. 2018 Aug 15;78(16):4627-4641. doi: 10.1158/0008-5472.CAN-17-1745. Epub 2018 May 22.


Factors predicting hypocalcemia after total thyroidectomy - A retrospective cohort analysis.

Falch C, Hornig J, Senne M, Braun M, Konigsrainer A, Kirschniak A, Muller S.

Int J Surg. 2018 Jul;55:46-50. doi: 10.1016/j.ijsu.2018.05.014. Epub 2018 May 16.


[Oligometastases in gastric and esophageal cancer : Current clinical trials and surgical concepts].

Beckert S, Königsrainer A.

Chirurg. 2018 Jul;89(7):505-509. doi: 10.1007/s00104-018-0645-y. Review. German.


Phase I Study of Oncolytic Vaccinia Virus GL-ONC1 in Patients with Peritoneal Carcinomatosis.

Lauer UM, Schell M, Beil J, Berchtold S, Koppenhöfer U, Glatzle J, Königsrainer A, Möhle R, Nann D, Fend F, Pfannenberg C, Bitzer M, Malek NP.

Clin Cancer Res. 2018 Sep 15;24(18):4388-4398. doi: 10.1158/1078-0432.CCR-18-0244. Epub 2018 May 17.


CT-Guided Translumbar Placement of Permanent Catheters in the Inferior Vena Cava: Description of the Technique with Technical Success and Complications Data.

Grözinger G, Grosse U, Syha R, Hoffmann R, Partovi S, Nikolaou K, Stahl S, Königsrainer A, Thiel K, Thiel C.

Cardiovasc Intervent Radiol. 2018 Sep;41(9):1356-1362. doi: 10.1007/s00270-018-1961-9. Epub 2018 Apr 19.


Extended right hepatectomy with inferior vena cava replacement for threatening venous outflow occlusion in a pretreated undifferentiated pleomorphic sarcoma of the liver.

Strohäker J, Bachmann R, Biegner T, Klumpp B, Königsrainer A, Ladurner R.

Minerva Chir. 2018 Apr;73(2):246-248. doi: 10.23736/S0026-4733.18.07521-1. Epub 2018 Jan 23. No abstract available.


Fully automated life support: an implementation and feasibility pilot study in healthy pigs.

Klingert W, Peter J, Thiel C, Thiel K, Rosenstiel W, Klingert K, Grasshoff C, Königsrainer A, Schenk M.

Intensive Care Med Exp. 2018 Jan 16;6(1):2. doi: 10.1186/s40635-018-0168-3.


Selecting living donors for uterus transplantation: lessons learned from two transplantations resulting in menstrual functionality and another attempt, aborted after organ retrieval.

Brucker SY, Brännström M, Taran FA, Nadalin S, Königsrainer A, Rall K, Schöller D, Henes M, Bösmüller H, Fend F, Nikolaou K, Notohamiprodjo M, Rosenberger P, Grasshoff C, Heim E, Krämer B, Reisenauer C, Hoopmann M, Kagan KO, Dahm-Kähler P, Kvarnström N, Wallwiener D.

Arch Gynecol Obstet. 2018 Mar;297(3):675-684. doi: 10.1007/s00404-017-4626-z. Epub 2017 Dec 21.


The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humans.

Peter A, Kovarova M, Staiger H, Machann J, Schick F, Königsrainer A, Königsrainer I, Schleicher E, Fritsche A, Häring HU, Stefan N.

Am J Physiol Endocrinol Metab. 2018 Mar 1;314(3):E266-E273. doi: 10.1152/ajpendo.00262.2017. Epub 2017 Nov 14.


Impact of surgical resection extension on outcome for primary well-differentiated thyroid cancer-a retrospective analysis.

Muller S, Senne M, Kirschniak A, Königsrainer A, Bares R, Falch C.

World J Surg Oncol. 2017 Oct 24;15(1):190. doi: 10.1186/s12957-017-1261-x.


Pathophysiological central nervous system changes in a porcine model of acetaminophen-induced acute liver failure.

Thiel C, Lauber J, Klingert W, Klingert K, Morgalla MH, Beschorner R, Peter A, Grasshoff C, Königsrainer A, Schenk M, Thiel K.

Toxicol Lett. 2017 Nov 5;281:119-126. doi: 10.1016/j.toxlet.2017.09.018. Epub 2017 Sep 27.


Dynamics of Glucose Metabolism After Kidney Transplantation.

Guthoff M, Wagner R, Weichbrodt K, Nadalin S, Königsrainer A, Häring HU, Fritsche A, Heyne N.

Kidney Blood Press Res. 2017;42(3):598-607. doi: 10.1159/000481375. Epub 2017 Sep 20.


Evaluation of a novel electrosurgical sealing mode in an ex vivo and in vivo porcine model.

Thiel K, Linzenbold W, Enderle MD, Nold B, Königsrainer A, Schenk M, Thiel C.

Surg Endosc. 2018 Mar;32(3):1456-1463. doi: 10.1007/s00464-017-5832-2. Epub 2017 Sep 18.


Algorithm-based arterial blood sampling recognition increasing safety in point-of-care diagnostics.

Peter J, Klingert W, Klingert K, Thiel K, Wulff D, Königsrainer A, Rosenstiel W, Schenk M.

World J Crit Care Med. 2017 Aug 4;6(3):172-178. doi: 10.5492/wjccm.v6.i3.172. eCollection 2017 Aug 4.


Metabolic crosstalk between fatty pancreas and fatty liver: effects on local inflammation and insulin secretion.

Gerst F, Wagner R, Kaiser G, Panse M, Heni M, Machann J, Bongers MN, Sartorius T, Sipos B, Fend F, Thiel C, Nadalin S, Königsrainer A, Stefan N, Fritsche A, Häring HU, Ullrich S, Siegel-Axel D.

Diabetologia. 2017 Nov;60(11):2240-2251. doi: 10.1007/s00125-017-4385-1. Epub 2017 Aug 8.


Gastric Ulcer Complications after the Introduction of Proton Pump Inhibitors into Clinical Routine: 20-Year Experience.

Eisner F, Hermann D, Bajaeifer K, Glatzle J, Königsrainer A, Küper MA.

Visc Med. 2017 Jun;33(3):221-226. doi: 10.1159/000475450. Epub 2017 Jun 16.


Safety and Tolerance of Donor-Derived Mesenchymal Stem Cells in Pediatric Living-Donor Liver Transplantation: The MYSTEP1 Study.

Hartleif S, Schumm M, Döring M, Mezger M, Lang P, Dahlke MH, Riethmüller J, Königsrainer A, Handgretinger R, Nadalin S, Sturm E.

Stem Cells Int. 2017;2017:2352954. doi: 10.1155/2017/2352954. Epub 2017 Jun 27.


Kidney Graft Salvage Strategies for Vascular Complications During Kidney Transplantation: A Single-center Experience.

Horvath P, Capobianco I, Rolinger J, Königsrainer A, Nadalin S, Königsrainer I.

Transplant Proc. 2017 Jul - Aug;49(6):1331-1335. doi: 10.1016/j.transproceed.2017.02.057.


Primary squamous cell carcinoma of the thyroid: Case report and systematic review of the literature.

Struller F, Senne M, Falch C, Kirschniak A, Konigsrainer A, Muller S.

Int J Surg Case Rep. 2017;37:36-40. doi: 10.1016/j.ijscr.2017.06.011. Epub 2017 Jun 13.


Sustained effects of a psychoeducational group intervention following bariatric surgery: follow-up of the randomized controlled BaSE study.

Wild B, Hünnemeyer K, Sauer H, Schellberg D, Müller-Stich BP, Königsrainer A, Weiner R, Zipfel S, Herzog W, Teufel M.

Surg Obes Relat Dis. 2017 Sep;13(9):1612-1618. doi: 10.1016/j.soard.2017.03.034. Epub 2017 Apr 1.


The protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A.

Wagner R, Machann J, Guthoff M, Nawroth PP, Nadalin S, Saleem MA, Heyne N, Königsrainer A, Fend F, Schick F, Fritsche A, Stefan N, Häring HU, Schleicher E, Siegel-Axel DI.

Sci Rep. 2017 May 23;7(1):2261. doi: 10.1038/s41598-017-02210-4.


Porcine model characterizing various parameters assessing the outcome after acetaminophen intoxication induced acute liver failure.

Thiel K, Klingert W, Klingert K, Morgalla MH, Schuhmann MU, Leckie P, Sharifi Y, Davies NA, Jalan R, Peter A, Grasshoff C, Königsrainer A, Schenk M, Thiel C.

World J Gastroenterol. 2017 Mar 7;23(9):1576-1585. doi: 10.3748/wjg.v23.i9.1576.


Surgical Therapy of Cholangiocarcinoma.

Radtke A, Königsrainer A.

Visc Med. 2016 Dec;32(6):422-426. doi: 10.1159/000452921. Epub 2016 Nov 30. Review.



Königsrainer A, Malek NP.

Visc Med. 2016 Dec;32(6):392. doi: 10.1159/000454847. Epub 2016 Dec 14. No abstract available.


Stimulation of Erythrocyte Cell Membrane Scrambling by C-Reactive Protein.

Abed M, Thiel C, Towhid ST, Alzoubi K, Honisch S, Lang F, Königsrainer A.

Cell Physiol Biochem. 2017;41(2):806-818. doi: 10.1159/000458745. Epub 2017 Feb 14.


Pharmacodynamics of Oxaliplatin-Derived Platinum Compounds During Hyperthermic Intraperitoneal Chemotherapy (HIPEC): An Emerging Aspect Supporting the Rational Design of Treatment Protocols.

Löffler MW, Schuster H, Zeck A, Quilitz N, Weinreich J, Tolios A, Haen SP, Horvath P, Löb S, Rammensee HG, Königsrainer I, Königsrainer A, Beckert S.

Ann Surg Oncol. 2017 Jun;24(6):1650-1657. doi: 10.1245/s10434-017-5790-x. Epub 2017 Feb 3.


Laparoscopically guided percutaneous choledochoscopy: minimally invasive interdisciplinary rendezvous for selected patients.

Zdichavsky M, Hirt B, Kramer A, Königsrainer A, Malek NP, Schweizer U, Goetz M.

Endoscopy. 2017 Feb;49(S 01):E29-E30. doi: 10.1055/s-0042-121487. Epub 2017 Jan 9. No abstract available.


Erratum to "Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient".

Löffler MW, Chandran PA, Laske K, Schroeder C, Bonzheim I, Walzer M, Hilke FJ, Trautwein N, Kowalewski DJ, Schuster H, Günder M, Carcamo Yañez VA, Mohr C, Sturm M, Nguyen HP, Riess O, Bauer P, Nahnsen S, Nadalin S, Zieker D, Glatzle J, Thiel K, Schneiderhan-Marra N, Clasen S, Bösmüller H, Fend F, Kohlbacher O, Gouttefangeas C, Stevanović S, Königsrainer A, Rammensee HG.

J Hepatol. 2017 Jan;66(1):252-253. doi: 10.1016/j.jhep.2016.10.021. Epub 2016 Nov 15. No abstract available.


Outcomes of pediatric identical living-donor liver and hematopoietic stem cell transplantation.

Hartleif S, Lang P, Handgretinger R, Feuchtinger T, Fuchs J, Königsrainer A, Nadalin S, Sturm E.

Pediatr Transplant. 2016 Nov;20(7):888-897. doi: 10.1111/petr.12725. Epub 2016 May 30.


Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4-AIO): results from the phase 2 part of a multicentre, open-label, randomised phase 2/3 trial.

Al-Batran SE, Hofheinz RD, Pauligk C, Kopp HG, Haag GM, Luley KB, Meiler J, Homann N, Lorenzen S, Schmalenberg H, Probst S, Koenigsmann M, Egger M, Prasnikar N, Caca K, Trojan J, Martens UM, Block A, Fischbach W, Mahlberg R, Clemens M, Illerhaus G, Zirlik K, Behringer DM, Schmiegel W, Pohl M, Heike M, Ronellenfitsch U, Schuler M, Bechstein WO, Königsrainer A, Gaiser T, Schirmacher P, Hozaeel W, Reichart A, Goetze TO, Sievert M, Jäger E, Mönig S, Tannapfel A.

Lancet Oncol. 2016 Dec;17(12):1697-1708. doi: 10.1016/S1470-2045(16)30531-9. Epub 2016 Oct 22.


Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity.

Lutz SZ, Peter A, Machicao F, Lamprinou A, Machann J, Schick F, Königsrainer I, Königsrainer A, Fritsche A, Staiger H, Häring HU, Stefan N, Kantartzis K.

J Clin Endocrinol Metab. 2016 Dec;101(12):4743-4751. Epub 2016 Oct 7.


Incidence of leukopenia after intraperitoneal vs combined intravenous/intraperitoneal chemotherapy in pseudomyxoma peritonei.

Horvath P, Beckert S, Struller F, Königsrainer A, Königsrainer I.

World J Gastrointest Pharmacol Ther. 2016 Aug 6;7(3):434-9. doi: 10.4292/wjgpt.v7.i3.434.


Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient.

Löffler MW, Chandran PA, Laske K, Schroeder C, Bonzheim I, Walzer M, Hilke FJ, Trautwein N, Kowalewski DJ, Schuster H, Günder M, Carcamo Yañez VA, Mohr C, Sturm M, Nguyen HP, Riess O, Bauer P, Nahnsen S, Nadalin S, Zieker D, Glatzle J, Thiel K, Schneiderhan-Marra N, Clasen S, Bösmüller H, Fend F, Kohlbacher O, Gouttefangeas C, Stevanović S, Königsrainer A, Rammensee HG.

J Hepatol. 2016 Oct;65(4):849-855. doi: 10.1016/j.jhep.2016.06.027. Epub 2016 Jul 7.


Neuronal Food Reward Activity in Patients With Type 2 Diabetes With Improved Glycemic Control After Bariatric Surgery.

Frank S, Heinze JM, Fritsche A, Linder K, von Feilitzsch M, Königsrainer A, Häring HU, Veit R, Preissl H.

Diabetes Care. 2016 Aug;39(8):1311-7. doi: 10.2337/dc16-0094. Epub 2016 Jun 12.


Relationship of Serum Trimethylamine N-Oxide (TMAO) Levels with early Atherosclerosis in Humans.

Randrianarisoa E, Lehn-Stefan A, Wang X, Hoene M, Peter A, Heinzmann SS, Zhao X, Königsrainer I, Königsrainer A, Balletshofer B, Machann J, Schick F, Fritsche A, Häring HU, Xu G, Lehmann R, Stefan N.

Sci Rep. 2016 May 27;6:26745. doi: 10.1038/srep26745.


Comparison of clinical outcome of laparoscopic versus open appendectomy for complicated appendicitis.

Horvath P, Lange J, Bachmann R, Struller F, Königsrainer A, Zdichavsky M.

Surg Endosc. 2017 Jan;31(1):199-205. doi: 10.1007/s00464-016-4957-z. Epub 2016 May 18.


Liposarcoma of the Spermatic Cord: Impact of Final Surgical Intervention--An Institutional Experience.

Bachmann R, Rolinger J, Girotti P, Kopp HG, Heissner K, Amend B, Königsrainer A, Ladurner R.

Int J Surg Oncol. 2016;2016:4785394. doi: 10.1155/2016/4785394. Epub 2016 Apr 14.


Growth hormone abolishes the negative effects of everolimus on intestinal wound healing.

Küper MA, Trütschel S, Weinreich J, Königsrainer A, Beckert S.

World J Gastroenterol. 2016 May 7;22(17):4321-9. doi: 10.3748/wjg.v22.i17.4321.


Hemangiopericytoma/solitary fibrous tumor of the greater omentum: A case report and review of the literature.

Archid R, Schneider CC, Adam P, Othman A, Zieker D, Königsrainer A.

Int J Surg Case Rep. 2016;23:160-2. doi: 10.1016/j.ijscr.2016.04.028. Epub 2016 Apr 21.


Living donor liver transplantation in Europe.

Nadalin S, Capobianco I, Panaro F, Di Francesco F, Troisi R, Sainz-Barriga M, Muiesan P, Königsrainer A, Testa G.

Hepatobiliary Surg Nutr. 2016 Apr;5(2):159-75. doi: 10.3978/j.issn.2304-3881.2015.10.04. Review.

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