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Virulence Profile: Renate König. König R et al. Virulence. (2018)

Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly. Aramillo Irizar P et al. Nat Commun. (2018)

Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies. Majer C et al. Med Microbiol Immunol. (2019)

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Items: 1 to 50 of 459


Reprogramming of macrophages employing gene regulatory and metabolic network models.

Hörhold F, Eisel D, Oswald M, Kolte A, Röll D, Osen W, Eichmüller SB, König R.

PLoS Comput Biol. 2020 Feb 25;16(2):e1007657. doi: 10.1371/journal.pcbi.1007657. [Epub ahead of print]


Generation of three induced pluripotent cell lines (iPSCs) from an Aicardi-Goutières syndrome (AGS) patient harboring a deletion in the genomic locus of the sterile alpha motif and HD domain containing protein 1 (SAMHD1).

Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, Wendeburg L, Steinemann D, Elpers C, Rutsch F, König R.

Stem Cell Res. 2020 Jan 9;43:101697. doi: 10.1016/j.scr.2019.101697. [Epub ahead of print]


[Autologous reconstructive surgery and intestinal rehabilitation in the management of short bowel syndrome].

Urbán D, Kőnig R, Cserni T.

Orv Hetil. 2020 Feb;161(7):243-251. doi: 10.1556/650.2020.31655. Hungarian.


Coherence imaging spectroscopy at Wendelstein 7-X for impurity flow measurements.

Perseo V, Gradic D, König R, Ford OP, Killer C, Grulke O, Ennis DA; W7-X Team.

Rev Sci Instrum. 2020 Jan 1;91(1):013501. doi: 10.1063/1.5126098.


Continuum Limits of Homogeneous Binary Trees and the Thompson Group.

Kliesch A, König R.

Phys Rev Lett. 2020 Jan 10;124(1):010601. doi: 10.1103/PhysRevLett.124.010601.


Sensor Sensibility-HIV-1 and the Innate Immune Response.

Yin X, Langer S, Zhang Z, Herbert KM, Yoh S, König R, Chanda SK.

Cells. 2020 Jan 20;9(1). pii: E254. doi: 10.3390/cells9010254. Review.


Modelling TERT regulation across 19 different cancer types based on the MIPRIP 2.0 gene regulatory network approach.

Poos AM, Kordaß T, Kolte A, Ast V, Oswald M, Rippe K, König R.

BMC Bioinformatics. 2019 Dec 30;20(1):737. doi: 10.1186/s12859-019-3323-2.


Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.

Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, Steinemann D, Göhring G, König R.

Stem Cell Res. 2020 Jan;42:101679. doi: 10.1016/j.scr.2019.101679. Epub 2019 Dec 4.


Cathelicidin Contributes to the Restriction of Leishmania in Human Host Macrophages.

Crauwels P, Bank E, Walber B, Wenzel UA, Agerberth B, Chanyalew M, Abebe M, König R, Ritter U, Reiling N, van Zandbergen G.

Front Immunol. 2019 Nov 22;10:2697. doi: 10.3389/fimmu.2019.02697. eCollection 2019.


Insights into Innate Sensing of Prototype Foamy Viruses in Myeloid Cells.

Bergez M, Weber J, Riess M, Erdbeer A, Seifried J, Stanke N, Munz C, Hornung V, König R, Lindemann D.

Viruses. 2019 Nov 26;11(12). pii: E1095. doi: 10.3390/v11121095.


Expression of CCCTC-binding factor (CTCF) is linked to poor prognosis in prostate cancer.

Höflmayer D, Steinhoff A, Hube-Magg C, Kluth M, Simon R, Burandt E, Tsourlakis MC, Minner S, Sauter G, Büscheck F, Wilczak W, Steurer S, Huland H, Graefen M, Haese A, Heinzer H, Schlomm T, Jacobsen F, Hinsch A, Poos AM, Oswald M, Rippe K, König R, Schroeder C.

Mol Oncol. 2020 Jan;14(1):129-138. doi: 10.1002/1878-0261.12597. Epub 2019 Nov 29.


Induced pluripotent stem cells (iPSCs) derived from a renpenning syndrome patient with c.459_462delAGAG mutation in PQBP1 (PEIi001-A).

Fuchs NV, Schieck M, Neuenkirch M, Tondera C, Schmitz H, des Portes V, Germanaud D, Steinemann D, Göhring G, König R.

Stem Cell Res. 2019 Dec;41:101592. doi: 10.1016/j.scr.2019.101592. Epub 2019 Oct 15.


Functional Integration of Neuronal Precursors in the Adult Murine Piriform Cortex.

Benedetti B, Dannehl D, König R, Coviello S, Kreutzer C, Zaunmair P, Jakubecova D, Weiger TM, Aigner L, Nacher J, Engelhardt M, Couillard-Després S.

Cereb Cortex. 2019 Oct 22. pii: bhz181. doi: 10.1093/cercor/bhz181. [Epub ahead of print]


Multicentric Registry Study on Epidemiological and Biological Disease Profile as Well as Clinical Outcome in Patients with Low-Grade Gliomas: The LoG-Glio Project.

Pala A, Nadji-Ohl M, Faust K, Rückriegel S, Roder C, von der Brelie C, Forster MT, Löbel F, Schommer S, Löhr M, Grübel N, Rothenbacher D, König R, Engelke J, Schmitz B, Wirtz CR, Senft C, Rohde V, Tatagiba M, Ernestus RI, Vajkoczy P, Ganslandt O, Nagel G, Coburger J.

J Neurol Surg A Cent Eur Neurosurg. 2020 Jan;81(1):48-57. doi: 10.1055/s-0039-1693650. Epub 2019 Sep 24.


Macrolide combination therapy for patients hospitalised with community-acquired pneumonia? An individualised approach supported by machine learning.

König R, Cao X, Oswald M, Forstner C, Rohde G, Rupp J, Witzenrath M, Welte T, Kolditz M, Pletz M; CAPNETZ study group.

Eur Respir J. 2019 Dec 12;54(6). pii: 1900824. doi: 10.1183/13993003.00824-2019. Print 2019 Dec.


ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53.

Osei Kuffour E, König R, Häussinger D, Schulz WA, Münk C.

mBio. 2019 Aug 27;10(4). pii: e01342-19. doi: 10.1128/mBio.01342-19.


First Observation of a Stable Highly Dissipative Divertor Plasma Regime on the Wendelstein 7-X Stellarator.

Zhang D, König R, Feng Y, Burhenn R, Brezinsek S, Jakubowski M, Buttenschön B, Niemann H, Pavone A, Krychowiak M, Kwak S, Svensson J, Gao Y, Pedersen TS, Alonso A, Baldzuhn J, Beidler CD, Biedermann C, Bozhenkov S, Brunner KJ, Damm H, Hirsch M, Giannone L, Drewelow P, Effenberg F, Fuchert G, Hammond KC, Höfel U, Killer C, Knauer J, Laqua HP, Laube R, Pablant N, Pasch E, Penzel F, Rahbarnia K, Reimold F, Thomsen H, Winters V, Wagner F, Klinger T, W-X Team.

Phys Rev Lett. 2019 Jul 12;123(2):025002. doi: 10.1103/PhysRevLett.123.025002.


Universal Uhrig Dynamical Decoupling for Bosonic Systems.

Heinze M, König R.

Phys Rev Lett. 2019 Jul 3;123(1):010501. doi: 10.1103/PhysRevLett.123.010501.


Clinical outcome after decompression of intraneural peroneal ganglion cyst and its morphologic correlation to postoperative nerve ultrasound.

Knoll A, Pal'a A, Pedro MT, Bäzner U, Schneider M, König RW, Wirtz CR, Friedrich S, Pauly M, Antoniadis G.

J Neurosurg. 2019 Jun 28:1-7. doi: 10.3171/2019.3.JNS182699. [Epub ahead of print]


Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.

Irizar PA, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C.

Nat Commun. 2019 May 31;10(1):2459. doi: 10.1038/s41467-019-10559-5.


Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.

Mallm JP, Iskar M, Ishaque N, Klett LC, Kugler SJ, Muino JM, Teif VB, Poos AM, Großmann S, Erdel F, Tavernari D, Koser SD, Schumacher S, Brors B, König R, Remondini D, Vingron M, Stilgenbauer S, Lichter P, Zapatka M, Mertens D, Rippe K.

Mol Syst Biol. 2019 May 22;15(5):e8339. doi: 10.15252/msb.20188339.


Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies.

Majer C, Schüssler JM, König R.

Med Microbiol Immunol. 2019 Aug;208(3-4):513-529. doi: 10.1007/s00430-019-00593-x. Epub 2019 Mar 16. Review.


Cognate Interaction With CD4+ T Cells Instructs Tumor-Associated Macrophages to Acquire M1-Like Phenotype.

Eisel D, Das K, Dickes E, König R, Osen W, Eichmüller SB.

Front Immunol. 2019 Feb 22;10:219. doi: 10.3389/fimmu.2019.00219. eCollection 2019.


The influence of nimodipine and vasopressors on outcome in patients with delayed cerebral ischemia after spontaneous subarachnoid hemorrhage.

Paľa A, Schick J, Klein M, Mayer B, Schmitz B, Wirtz CR, König R, Kapapa T.

J Neurosurg. 2019 Mar 8:1-9. doi: 10.3171/2018.11.JNS182891. [Epub ahead of print]


Explaining event-related fields by a mechanistic model encapsulating the anatomical structure of auditory cortex.

Hajizadeh A, Matysiak A, May PJC, König R.

Biol Cybern. 2019 Jun;113(3):321-345. doi: 10.1007/s00422-019-00795-9. Epub 2019 Feb 28.


Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation.

Kresinsky A, Schnöder TM, Jacobsen ID, Rauner M, Hofbauer LC, Ast V, König R, Hoffmann B, Svensson CM, Figge MT, Hilger I, Heidel FH, Böhmer FD, Müller JP.

Oncogene. 2019 Jun;38(24):4773-4787. doi: 10.1038/s41388-019-0757-y. Epub 2019 Feb 28.


Effect of Powdered Activated Carbon as Advanced Step in Wastewater Treatments on Antibiotic Resistant Microorganisms.

Ravasi D, König R, Principi P, Perale G, Demarta A.

Curr Pharm Biotechnol. 2019;20(1):63-75. doi: 10.2174/1389201020666190207095556.


Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4.

Steinbrecht S, König R, Schmidtke KU, Herzog N, Scheibner K, Krüger-Genge A, Jung F, Kammerer S, Küpper JH.

Toxicology. 2019 Jan 15;412:37-47. doi: 10.1016/j.tox.2018.11.008. Epub 2018 Nov 27.


MiR-192, miR-200c and miR-17 are fibroblast-mediated inhibitors of colorectal cancer invasion.

Ast V, Kordaß T, Oswald M, Kolte A, Eisel D, Osen W, Eichmüller SB, Berndt A, König R.

Oncotarget. 2018 Oct 30;9(85):35559-35580. doi: 10.18632/oncotarget.26263. eCollection 2018 Oct 30.


Loss of CCAAT-enhancer-binding protein alpha (CEBPA) is linked to poor prognosis in PTEN deleted and TMPRSS2:ERG fusion type prostate cancers.

Minner S, Lutz J, Hube-Magg C, Kluth M, Simon R, Höflmayer D, Burandt E, Tsourlakis MC, Sauter G, Büscheck F, Wilczak W, Steurer S, Schlomm T, Huland H, Graefen M, Haese A, Heinzer H, Jacobsen F, Hinsch A, Poos A, Oswald M, Rippe K, König R, Schroeder C.

Prostate. 2019 Feb;79(3):302-311. doi: 10.1002/pros.23736. Epub 2018 Nov 14.


Infrared imaging systems for wall protection in the W7-X stellarator (invited).

Jakubowski M, Drewelow P, Fellinger J, Puig Sitjes A, Wurden G, Ali A, Biedermann C, Cannas B, Chauvin D, Gamradt M, Greve H, Gao Y, Hathiramani D, König R, Lorenz A, Moncada V, Niemann H, Ngo TT, Pisano F, Sunn Pedersen T; W7-XTeam.

Rev Sci Instrum. 2018 Oct;89(10):10E116. doi: 10.1063/1.5038634.


Quantum advantage with shallow circuits.

Bravyi S, Gosset D, König R.

Science. 2018 Oct 19;362(6412):308-311. doi: 10.1126/science.aar3106.


Quality of Life After Treatment of Unruptured Intracranial Aneurysms.

Pala A, Pawlikowski A, Brand C, Schmitz B, Wirtz CR, König R, Kapapa T.

World Neurosurg. 2019 Jan;121:e54-e59. doi: 10.1016/j.wneu.2018.09.010. Epub 2018 Sep 20.


USP18 (UBP43) Abrogates p21-Mediated Inhibition of HIV-1.

Osei Kuffour E, Schott K, Jaguva Vasudevan AA, Holler J, Schulz WA, Lang PA, Lang KS, Kim B, Häussinger D, König R, Münk C.

J Virol. 2018 Sep 26;92(20). pii: e00592-18. doi: 10.1128/JVI.00592-18. Print 2018 Oct 15.


Timepoints of vancomycin-resistant Enterococcus colonization predict outcomes of acute myeloid leukemia patients undergoing allogeneic hematopoietic cell transplantation.

Scheich S, Weber S, König R, Wilke AC, Lindner S, Reinheimer C, Wichelhaus TA, Hogardt M, A J Kempf V, Kessel J, Martin H, Bug G, Serve H, Steffen B.

Eur J Haematol. 2018 Jul 26. doi: 10.1111/ejh.13151. [Epub ahead of print]


Y-box-binding protein 1 supports the early and late steps of HIV replication.

Weydert C, van Heertum B, Dirix L, De Houwer S, De Wit F, Mast J, Husson SJ, Busschots K, König R, Gijsbers R, De Rijck J, Debyser Z.

PLoS One. 2018 Jul 11;13(7):e0200080. doi: 10.1371/journal.pone.0200080. eCollection 2018.


Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit.

Schott K, Fuchs NV, Derua R, Mahboubi B, Schnellbächer E, Seifried J, Tondera C, Schmitz H, Shepard C, Brandariz-Nuñez A, Diaz-Griffero F, Reuter A, Kim B, Janssens V, König R.

Nat Commun. 2018 Jun 8;9(1):2227. doi: 10.1038/s41467-018-04671-1.


Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in FLT3-ITD acute myeloid leukemia.

Kresinsky A, Bauer R, Schnöder TM, Berg T, Meyer D, Ast V, König R, Serve H, Heidel FH, Böhmer FD, Müller JP.

Haematologica. 2018 Nov;103(11):e505-e509. doi: 10.3324/haematol.2017.185306. Epub 2018 Jun 7. No abstract available.


Diagnostic accuracy of intraoperative perfusion-weighted MRI and 5-aminolevulinic acid in relation to contrast-enhanced intraoperative MRI and 11C-methionine positron emission tomography in resection of glioblastoma: a prospective study.

Pala A, Reske SN, Eberhardt N, Scheuerle A, König R, Schmitz B, Beer AJ, Wirtz CR, Coburger J.

Neurosurg Rev. 2019 Jun;42(2):471-479. doi: 10.1007/s10143-018-0987-4. Epub 2018 May 28.


The evolution of invasive cerebral vasospasm treatment in patients with spontaneous subarachnoid hemorrhage and delayed cerebral ischemia-continuous selective intracarotid nimodipine therapy in awake patients without sedation.

Paľa A, Schneider M, Brand C, Pedro MT, Özpeynirci Y, Schmitz B, Wirtz CR, Kapapa T, König R, Braun M.

Neurosurg Rev. 2019 Jun;42(2):463-469. doi: 10.1007/s10143-018-0986-5. Epub 2018 May 26.


Cellular Plasticity in the Adult Murine Piriform Cortex: Continuous Maturation of Dormant Precursors Into Excitatory Neurons.

Rotheneichner P, Belles M, Benedetti B, König R, Dannehl D, Kreutzer C, Zaunmair P, Engelhardt M, Aigner L, Nacher J, Couillard-Despres S.

Cereb Cortex. 2018 Jul 1;28(7):2610-2621. doi: 10.1093/cercor/bhy087.


Accurate IVIM model-based liver lesion characterisation can be achieved with only three b-value DWI.

Mürtz P, Sprinkart AM, Reick M, Pieper CC, Schievelkamp AH, König R, Schild HH, Willinek WA, Kukuk GM.

Eur Radiol. 2018 Oct;28(10):4418-4428. doi: 10.1007/s00330-018-5401-7. Epub 2018 Apr 18.


Clipping as re-treatment strategy after treatment of a cerebral aneurysm with the Woven EndoBridge embolization device: case report.

Durner G, Özpeynirci Y, Schmitz B, Wirtz CR, König R, Pala A.

J Neurosurg. 2018 Mar 1:1-4. doi: 10.3171/2017.10.JNS171528. [Epub ahead of print]


Role of Three-Dimensional Rotational Angiography in the Treatment of Spinal Dural Arteriovenous Fistulas.

Ozpeynirci Y, Schmitz B, Schick M, Konig R.

Cureus. 2017 Dec 10;9(12):e1932. doi: 10.7759/cureus.1932.


Upregulation of cell cycle genes in head and neck cancer patients may be antagonized by erufosine's down regulation of cell cycle processes in OSCC cells.

Ansari SS, Sharma AK, Zepp M, Ivanova E, Bergmann F, König R, Berger MR.

Oncotarget. 2017 Dec 20;9(5):5797-5810. doi: 10.18632/oncotarget.23537. eCollection 2018 Jan 19.


Induction of ER and mitochondrial stress by the alkylphosphocholine erufosine in oral squamous cell carcinoma cells.

Ansari SS, Sharma AK, Soni H, Ali DM, Tews B, König R, Eibl H, Berger MR.

Cell Death Dis. 2018 Feb 20;9(3):296. doi: 10.1038/s41419-018-0342-2.


Is MGMT promoter methylation to be considered in the decision making for recurrent surgery in glioblastoma patients?

Pala A, Schmitz AL, Knoll A, Schneider M, Hlavac M, König R, Wirtz CR, Coburger J.

Clin Neurol Neurosurg. 2018 Apr;167:6-10. doi: 10.1016/j.clineuro.2018.02.003. Epub 2018 Feb 5.


First results of the multi-purpose real-time processing video camera system on the Wendelstein 7-X stellarator and implications for future devices.

Zoletnik S, Biedermann C, Cseh G, Kocsis G, König R, Szabolics T, Szepesi T; Wendelstein 7-X Team.

Rev Sci Instrum. 2018 Jan;89(1):013502. doi: 10.1063/1.4995947.


Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.

Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, Krawczak M, Ristow M, Schuster S, Cellerino A, Diekmann S, Englert C, Hemmerich P, Sühnel J, Guthke R, Witte OW, Platzer M, Ruppin E, Kaleta C.

Nat Commun. 2018 Jan 30;9(1):327. doi: 10.1038/s41467-017-02395-2. Erratum in: Nat Commun. 2019 May 31;10(1):2459.

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