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Items: 31


Medical Deferred Action - Living on Borrowed Time.

Ganapathi L, Caldas A, Miranda J, Köhler JR, Visner G, Sawicki G.

N Engl J Med. 2019 Oct 24;381(17):1601-1603. doi: 10.1056/NEJMp1911907. Epub 2019 Oct 2. No abstract available.


Candida albicans Dispersed Cells Are Developmentally Distinct from Biofilm and Planktonic Cells.

Uppuluri P, Acosta Zaldívar M, Anderson MZ, Dunn MJ, Berman J, Lopez Ribot JL, Köhler JR.

mBio. 2018 Aug 21;9(4). pii: e01338-18. doi: 10.1128/mBio.01338-18.


Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence.

Liu NN, Uppuluri P, Broggi A, Besold A, Ryman K, Kambara H, Solis N, Lorenz V, Qi W, Acosta-Zaldívar M, Emami SN, Bao B, An D, Bonilla FA, Sola-Visner M, Filler SG, Luo HR, Engström Y, Ljungdahl PO, Culotta VC, Zanoni I, Lopez-Ribot JL, Köhler JR.

PLoS Pathog. 2018 Jul 30;14(7):e1007076. doi: 10.1371/journal.ppat.1007076. eCollection 2018 Jul.


The Human Gut Microbial Metabolome Modulates Fungal Growth via the TOR Signaling Pathway.

García C, Tebbji F, Daigneault M, Liu NN, Köhler JR, Allen-Vercoe E, Sellam A.

mSphere. 2017 Dec 13;2(6). pii: e00555-17. doi: 10.1128/mSphere.00555-17. eCollection 2017 Nov-Dec.


The Candida albicans TOR-Activating GTPases Gtr1 and Rhb1 Coregulate Starvation Responses and Biofilm Formation.

Flanagan PR, Liu NN, Fitzpatrick DJ, Hokamp K, Köhler JR, Moran GP.

mSphere. 2017 Nov 15;2(6). pii: e00477-17. doi: 10.1128/mSphere.00477-17. eCollection 2017 Nov-Dec.


Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems.

Santus W, Barresi S, Mingozzi F, Broggi A, Orlandi I, Stamerra G, Vai M, Martorana AM, Polissi A, Köhler JR, Liu N, Zanoni I, Granucci F.

Sci Immunol. 2017 Sep 22;2(15). pii: eaan2725. doi: 10.1126/sciimmunol.aan2725.


Hepatic Legionella pneumophila Infection in an Infant With Severe Combined Immunodeficiency.

Lapidot R, Alawdah L, Köhler JR, Paulson V, Levy O.

Pediatr Infect Dis J. 2018 Apr;37(4):356-358. doi: 10.1097/INF.0000000000001789.


Boron Partitioning Coefficient above Unity in Laser Crystallized Silicon.

Lill PC, Dahlinger M, Köhler JR.

Materials (Basel). 2017 Feb 16;10(2). pii: E189. doi: 10.3390/ma10020189.


Fungi that Infect Humans.

Köhler JR, Hube B, Puccia R, Casadevall A, Perfect JR.

Microbiol Spectr. 2017 Jun;5(3). doi: 10.1128/microbiolspec.FUNK-0014-2016. Review.


Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.

Liu NN, Flanagan PR, Zeng J, Jani NM, Cardenas ME, Moran GP, Köhler JR.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6346-6351. doi: 10.1073/pnas.1617799114. Epub 2017 May 31.


Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, Blocks Candida albicans Morphogenesis, and Is Effluxed via Yor1 and Circuitry Controlled by Zcf29.

Shekhar-Guturja T, Tebung WA, Mount H, Liu N, Köhler JR, Whiteway M, Cowen LE.

Antimicrob Agents Chemother. 2016 Nov 21;60(12):7468-7480. Print 2016 Dec.


Pulsed Laser Porosification of Silicon Thin Films.

Sämann C, Köhler JR, Dahlinger M, Schubert MB, Werner JH.

Materials (Basel). 2016 Jun 24;9(7). pii: E509. doi: 10.3390/ma9070509.


Antagonism of Fluconazole and a Proton Pump Inhibitor against Candida albicans.

Liu NN, Köhler JR.

Antimicrob Agents Chemother. 2015 Nov 23;60(2):1145-7. doi: 10.1128/AAC.02043-15. Print 2016 Feb.


Ribosomal protein S6 phosphorylation is controlled by TOR and modulated by PKA in Candida albicans.

Chowdhury T, Köhler JR.

Mol Microbiol. 2015 Oct;98(2):384-402. doi: 10.1111/mmi.13130. Epub 2015 Aug 22.


The spectrum of fungi that infects humans.

Köhler JR, Casadevall A, Perfect J.

Cold Spring Harb Perspect Med. 2014 Nov 3;5(1):a019273. doi: 10.1101/cshperspect.a019273. Review.


Analytical strategies for discovery and replication of genetic effects in pharmacogenomic studies.

Kohler JR, Guennel T, Marshall SL.

Pharmgenomics Pers Med. 2014 Aug 13;7:217-25. doi: 10.2147/PGPM.S66841. eCollection 2014.


The silent crisis: children hurt by current immigration enforcement policies.

Köhler JR, Sola-Visner M.

JAMA Pediatr. 2014 Feb;168(2):103-4. doi: 10.1001/jamapediatrics.2013.4350. No abstract available.


Physiologic expression of the Candida albicans pescadillo homolog is required for virulence in a murine model of hematogenously disseminated candidiasis.

Uppuluri P, Chaturvedi AK, Jani N, Pukkila-Worley R, Monteagudo C, Mylonakis E, Köhler JR, Lopez Ribot JL.

Eukaryot Cell. 2012 Dec;11(12):1552-6. doi: 10.1128/EC.00171-12. Epub 2012 Oct 26.


Dispersion as an important step in the Candida albicans biofilm developmental cycle.

Uppuluri P, Chaturvedi AK, Srinivasan A, Banerjee M, Ramasubramaniam AK, Köhler JR, Kadosh D, Lopez-Ribot JL.

PLoS Pathog. 2010 Mar 26;6(3):e1000828. doi: 10.1371/journal.ppat.1000828.


Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease.

Cowen LE, Singh SD, Köhler JR, Collins C, Zaas AK, Schell WA, Aziz H, Mylonakis E, Perfect JR, Whitesell L, Lindquist S.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2818-23. doi: 10.1073/pnas.0813394106. Epub 2009 Feb 5.


The Candida albicans pescadillo homolog is required for normal hypha-to-yeast morphogenesis and yeast proliferation.

Shen J, Cowen LE, Griffin AM, Chan L, Köhler JR.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20918-23. doi: 10.1073/pnas.0809147105. Epub 2008 Dec 15.


Mucosal damage and neutropenia are required for Candida albicans dissemination.

Koh AY, Köhler JR, Coggshall KT, Van Rooijen N, Pier GB.

PLoS Pathog. 2008 Feb 8;4(2):e35. doi: 10.1371/journal.ppat.0040035.


Simultaneous discovery and testing of deletions for disease association in SNP genotyping studies.

Kohler JR, Cutler DJ.

Am J Hum Genet. 2007 Oct;81(4):684-99. Epub 2007 Aug 14.


Long-term effects of reflux nephropathy on blood pressure and renal function in adults.

Köhler JR, Tencer J, Thysell H, Forsberg L, Hellström M.

Nephron Clin Pract. 2003 Jan;93(1):C35-46.


Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations.

Orange JS, Brodeur SR, Jain A, Bonilla FA, Schneider LC, Kretschmer R, Nurko S, Rasmussen WL, Köhler JR, Gellis SE, Ferguson BM, Strominger JL, Zonana J, Ramesh N, Ballas ZK, Geha RS.

J Clin Invest. 2002 Jun;109(11):1501-9.


Detecting legionellosis by unselected culture of respiratory tract secretions and developing links to hospital water strains.

Köhler JR, Maiwald M, Lück PC, Helbig JH, Hingst V, Sonntag HG.

J Hosp Infect. 1999 Apr;41(4):301-11.


Nonfilamentous C. albicans mutants are avirulent.

Lo HJ, Köhler JR, DiDomenico B, Loebenberg D, Cacciapuoti A, Fink GR.

Cell. 1997 Sep 5;90(5):939-49.

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