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Items: 1 to 50 of 221

1.

Large-scale Production of LGR5-positive Bipotential Human Liver Stem Cells.

Schneeberger K, Sánchez-Romero N, Ye S, van Steenbeek FG, Oosterhoff LA, Pla Palacin I, Chen C, van Wolferen ME, van Tienderen G, Lieshout R, Colemonts-Vroninks H, Schene I, Hoekstra R, Verstegen MMA, van der Laan LJW, Penning LC, Fuchs SA, Clevers H, De Kock J, Baptista PM, Spee B.

Hepatology. 2019 Nov 12. doi: 10.1002/hep.31037. [Epub ahead of print]

PMID:
31715015
2.

A robust bacterial assay for high-throughput screening of human 4-hydroxyphenylpyruvate dioxygenase inhibitors.

Neuckermans J, Mertens A, De Win D, Schwaneberg U, De Kock J.

Sci Rep. 2019 Oct 2;9(1):14145. doi: 10.1038/s41598-019-50533-1.

3.

Transcriptomics data of a human in vitro model of non-alcoholic steatohepatitis exposed to elafibranor.

Boeckmans J, Buyl K, Natale A, Vandenbempt V, Branson S, De Boe V, Rogiers V, De Kock J, Rodrigues RM, Vanhaecke T.

Data Brief. 2019 Jun 3;25:104093. doi: 10.1016/j.dib.2019.104093. eCollection 2019 Aug.

4.

Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment.

Markouli C, Couvreu De Deckersberg E, Regin M, Nguyen HT, Zambelli F, Keller A, Dziedzicka D, De Kock J, Tilleman L, Van Nieuwerburgh F, Franceschini L, Sermon K, Geens M, Spits C.

Stem Cell Reports. 2019 Jul 9;13(1):163-176. doi: 10.1016/j.stemcr.2019.05.005. Epub 2019 Jun 6.

5.

Technological advancements for the development of stem cell-based models for hepatotoxicity testing.

Natale A, Vanmol K, Arslan A, Van Vlierberghe S, Dubruel P, Van Erps J, Thienpont H, Buzgo M, Boeckmans J, De Kock J, Vanhaecke T, Rogiers V, Rodrigues RM.

Arch Toxicol. 2019 Jul;93(7):1789-1805. doi: 10.1007/s00204-019-02465-y. Epub 2019 Apr 29. Review.

PMID:
31037322
6.

Elafibranor restricts lipogenic and inflammatory responses in a human skin stem cell-derived model of NASH.

Boeckmans J, Buyl K, Natale A, Vandenbempt V, Branson S, De Boe V, Rogiers V, De Kock J, Rodrigues RM, Vanhaecke T.

Pharmacol Res. 2019 Jun;144:377-389. doi: 10.1016/j.phrs.2019.04.016. Epub 2019 Apr 24.

PMID:
31028903
7.

Comment to 'Letter to the editor: Human-based systems: Mechanistic NASH modelling just around the corner?'

Boeckmans J, Natale A, Buyl K, Rogiers V, De Kock J, Vanhaecke T, Rodrigues RM.

Pharmacol Res. 2018 Nov;137:282-283. doi: 10.1016/j.phrs.2018.09.029. Epub 2018 Oct 10. No abstract available.

PMID:
30315967
8.

Human-based systems: Mechanistic NASH modelling just around the corner?

Boeckmans J, Natale A, Buyl K, Rogiers V, De Kock J, Vanhaecke T, Rodrigues RM.

Pharmacol Res. 2018 Aug;134:257-267. doi: 10.1016/j.phrs.2018.06.029. Epub 2018 Jun 30. Review.

9.

Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures.

Rodrigues RM, Kollipara L, Chaudhari U, Sachinidis A, Zahedi RP, Sickmann A, Kopp-Schneider A, Jiang X, Keun H, Hengstler J, Oorts M, Annaert P, Hoeben E, Gijbels E, De Kock J, Vanhaecke T, Rogiers V, Vinken M.

Arch Toxicol. 2018 Jun;92(6):1939-1952. doi: 10.1007/s00204-018-2214-z. Epub 2018 May 14.

10.

Being in a bubble - Childbirth as a potential path towards becoming in health - Lived experiences of mothers during childbirth.

Hemberg JAV, Kock J.

Scand J Caring Sci. 2018 Dec;32(4):1348-1358. doi: 10.1111/scs.12580. Epub 2018 Apr 25.

PMID:
29693256
11.

Hepatic cells derived from human skin progenitors show a typical phospholipidotic response upon exposure to amiodarone.

Natale A, Boeckmans J, Desmae T, De Boe V, De Kock J, Vanhaecke T, Rogiers V, Rodrigues RM.

Toxicol Lett. 2018 Mar 1;284:184-194. doi: 10.1016/j.toxlet.2017.11.014. Epub 2017 Dec 15.

PMID:
29248575
12.

Upregulation of sodium taurocholate cotransporter polypeptide during hepatogenic differentiation of umbilical cord matrix mesenchymal stem cells facilitates hepatitis B entry.

Sargiacomo C, El-Kehdy H, Dallmeier K, de Kock J, Hernandez-Kelly C, Rogiers V, Ortega A, Neyts J, Sokal E, Najimi M.

Stem Cell Res Ther. 2017 Sep 29;8(1):204. doi: 10.1186/s13287-017-0656-5.

13.

A situation analysis of psychiatrists in South Africa's rural primary healthcare settings.

De Kock JH, Pillay BJ.

Afr J Prim Health Care Fam Med. 2017 May 29;9(1):e1-e6. doi: 10.4102/phcfm.v9i1.1335.

14.

Primary Human Testicular Cells Self-Organize into Organoids with Testicular Properties.

Baert Y, De Kock J, Alves-Lopes JP, Söder O, Stukenborg JB, Goossens E.

Stem Cell Reports. 2017 Jan 10;8(1):30-38. doi: 10.1016/j.stemcr.2016.11.012. Epub 2016 Dec 22.

15.

An induction or flare of arthritis and/or sacroiliitis by vedolizumab in inflammatory bowel disease: a case series.

Varkas G, Thevissen K, De Brabanter G, Van Praet L, Czul-Gurdian F, Cypers H, De Kock J, Carron P, De Vos M, Hindryckx P, Arts J, Vanneuville I, Schoenaers P, Claerhout B, Abreu M, Van den Bosch F, Elewaut D.

Ann Rheum Dis. 2017 May;76(5):878-881. doi: 10.1136/annrheumdis-2016-210233. Epub 2016 Nov 29.

PMID:
27899374
16.

Gene expression data from acetaminophen-induced toxicity in human hepatic in vitro systems and clinical liver samples.

Rodrigues RM, Govaere O, Roskams T, Vanhaecke T, Rogiers V, De Kock J.

Data Brief. 2016 Mar 26;7:1052-1057. eCollection 2016 Jun.

17.

Mental health nurses in South Africa's public rural primary care settings: a human resource crisis.

De Kock JH, Pillay BJ.

Rural Remote Health. 2016 Jul-Sep;16(3):3865. Epub 2016 Jul 18.

18.

Rapidly growing gastric metastasis of Merkel cell carcinoma, an unusual cause of melena.

Hulstaert E, Smith V, Mielants H, Van Praet L, De Kock J, Lambrecht V, Rasschaert G, Van Belle S.

Acta Clin Belg. 2016 Aug;71(4):263-6. doi: 10.1080/17843286.2015.1105612. Epub 2016 Feb 3.

PMID:
27075789
19.

Development and characterization of a new human hepatic cell line.

Ramboer E, De Craene B, De Kock J, Berx G, Rogiers V, Vanhaecke T, Vinken M.

EXCLI J. 2015 Jul 28;14:875-89. doi: 10.17179/excli2015-424. eCollection 2015.

21.

Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.

Rodrigues RM, Heymans A, De Boe V, Sachinidis A, Chaudhari U, Govaere O, Roskams T, Vanhaecke T, Rogiers V, De Kock J.

Toxicol Lett. 2016 Jan 5;240(1):50-9. doi: 10.1016/j.toxlet.2015.10.014. Epub 2015 Oct 20.

PMID:
26497421
22.

Vemurafenib-associated Dupuytren- and Ledderhose palmoplantar fibromatosis in metastatic melanoma patients.

Vandersleyen V, Grosber M, Wilgenhof S, De Kock J, Neyns B, Gutermuth J.

J Eur Acad Dermatol Venereol. 2016 Jul;30(7):1133-5. doi: 10.1111/jdv.13268. Epub 2015 Aug 24.

PMID:
26303964
23.

Measurement of Albumin Secretion as Functionality Test in Primary Hepatocyte Cultures.

Buyl K, De Kock J, Bolleyn J, Rogiers V, Vanhaecke T.

Methods Mol Biol. 2015;1250:303-8. doi: 10.1007/978-1-4939-2074-7_22.

PMID:
26272152
24.

Measurement of Cytochrome P450 Enzyme Induction and Inhibition in Human Hepatoma Cells.

Rodrigues RM, De Kock J, Doktorova TY, Rogiers V, Vanhaecke T.

Methods Mol Biol. 2015;1250:279-85. doi: 10.1007/978-1-4939-2074-7_20.

PMID:
26272150
25.

Human Skin-Derived Precursor Cells: Isolation, Expansion, and Hepatic Differentiation.

De Kock J, Rodrigues RM, Buyl K, Vanhaecke T, Rogiers V.

Methods Mol Biol. 2015;1250:113-22. doi: 10.1007/978-1-4939-2074-7_8.

PMID:
26272138
26.

Use of morphine sulphate by South African paramedics for prehospital pain management.

Vincent-Lambert C, de Kock JM.

Pain Res Manag. 2015 May-Jun;20(3):141-4.

27.

Neuropeptide FF receptors as novel targets for limbic seizure attenuation.

Portelli J, Meurs A, Bihel F, Hammoud H, Schmitt M, De Kock J, Utard V, Humbert JP, Bertin I, Buffel I, Coppens J, Tourwe D, Maes V, De Prins A, Vanhaecke T, Massie A, Balasubramaniam A, Boon P, Bourguignon JJ, Simonin F, Smolders I.

Neuropharmacology. 2015 Aug;95:415-23. doi: 10.1016/j.neuropharm.2015.04.030. Epub 2015 May 9.

PMID:
25963417
28.

In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells.

Rodrigues RM, Branson S, De Boe V, Sachinidis A, Rogiers V, De Kock J, Vanhaecke T.

Arch Toxicol. 2016 Mar;90(3):677-89. doi: 10.1007/s00204-015-1483-z. Epub 2015 Feb 26.

PMID:
25716160
29.

Evaluation of a new standardized enzymatic isolation protocol for human umbilical cord-derived stem cells.

Buyl K, Vanhaecke T, Desmae T, Lagneaux L, Rogiers V, Najar M, De Kock J.

Toxicol In Vitro. 2015 Sep;29(6):1254-62. doi: 10.1016/j.tiv.2014.12.008. Epub 2014 Dec 23.

PMID:
25541070
30.

Derivation and characterization of a cytocompatible scaffold from human testis.

Baert Y, Stukenborg JB, Landreh M, De Kock J, Jörnvall H, Söder O, Goossens E.

Hum Reprod. 2015 Feb;30(2):256-67. doi: 10.1093/humrep/deu330. Epub 2014 Dec 11.

PMID:
25505010
31.

Identification of potential biomarkers of hepatitis B-induced acute liver failure using hepatic cells derived from human skin precursors.

Rodrigues RM, Sachinidis A, De Boe V, Rogiers V, Vanhaecke T, De Kock J.

Toxicol In Vitro. 2015 Sep;29(6):1231-9. doi: 10.1016/j.tiv.2014.10.012. Epub 2014 Oct 24.

PMID:
25458485
32.

MicroRNAs as key regulators of xenobiotic biotransformation and drug response.

Bolleyn J, De Kock J, Rodrigues RM, Vinken M, Rogiers V, Vanhaecke T.

Arch Toxicol. 2015 Sep;89(9):1523-41. doi: 10.1007/s00204-014-1314-7. Epub 2014 Jul 31. Review.

PMID:
25079447
33.

Proliferative and phenotypical characteristics of human adipose tissue-derived stem cells: comparison of Ficoll gradient centrifugation and red blood cell lysis buffer treatment purification methods.

Najar M, Rodrigues RM, Buyl K, Branson S, Vanhaecke T, Lagneaux L, Rogiers V, De Kock J.

Cytotherapy. 2014 Sep;16(9):1220-8. doi: 10.1016/j.jcyt.2014.05.021. Epub 2014 Jul 22.

PMID:
25065636
34.

Nuclear factor of activated T cells regulates the expression of interleukin-4 in Th2 cells in an all-or-none fashion.

Köck J, Kreher S, Lehmann K, Riedel R, Bardua M, Lischke T, Jargosch M, Haftmann C, Bendfeldt H, Hatam F, Mashreghi MF, Baumgrass R, Radbruch A, Chang HD.

J Biol Chem. 2014 Sep 26;289(39):26752-61. doi: 10.1074/jbc.M114.587865. Epub 2014 Jul 17.

35.

Strategies for immortalization of primary hepatocytes.

Ramboer E, De Craene B, De Kock J, Vanhaecke T, Berx G, Rogiers V, Vinken M.

J Hepatol. 2014 Oct;61(4):925-43. doi: 10.1016/j.jhep.2014.05.046. Epub 2014 Jun 6. Review.

36.

Ten-year followup of infliximab therapy in rheumatoid arthritis patients with severe, longstanding refractory disease: a cohort study.

De Keyser F, De Kock J, Leroi H, Durez P, Westhovens R; Infliximab EAP Study Group.

J Rheumatol. 2014 Jul;41(7):1276-81. doi: 10.3899/jrheum.131270. Epub 2014 Jun 1.

PMID:
24882838
37.

Auger-architectomics: introducing a new nanotechnology to infectious disease.

Swart CW, Pohl CH, Kock JL.

Adv Exp Med Biol. 2014;807:1-8. doi: 10.1007/978-81-322-1777-0_1. Review.

PMID:
24619614
38.

Human skin-derived precursor cells are poorly immunogenic and modulate the allogeneic immune response.

De Kock J, Meuleman P, Raicevic G, Rodrigues RM, Branson S, Meganathan K, De Boe V, Sachinidis A, Leroux-Roels G, Vanhaecke T, Lagneaux L, Rogiers V, Najar M.

Stem Cells. 2014 Aug;32(8):2215-28. doi: 10.1002/stem.1692.

39.

Virulence of South African Candida albicans strains isolated from different clinical samples.

Ells R, Kilian W, Hugo A, Albertyn J, Kock JL, Pohl CH.

Med Mycol. 2014 Apr;52(3):246-53. doi: 10.1093/mmy/myt013. Epub 2014 Feb 24.

PMID:
24577008
40.

Human stem cell-derived hepatocytes: breakthrough of an expedient tool for preclinical assessment of drug-induced liver injury?

Rodrigues RM, De Kock J.

Arch Toxicol. 2014 Feb;88(2):183-4. doi: 10.1007/s00204-014-1199-5. Epub 2014 Jan 22. No abstract available.

PMID:
24448835
41.

Oxidized fatty acids as inter-kingdom signaling molecules.

Pohl CH, Kock JL.

Molecules. 2014 Jan 20;19(1):1273-85. doi: 10.3390/molecules19011273. Review.

42.

Phenothiazine is a potent inhibitor of prostaglandin E2 production by Candida albicans biofilms.

Ells R, Kemp G, Albertyn J, Kock JL, Pohl CH.

FEMS Yeast Res. 2013 Dec;13(8):849-55. doi: 10.1111/1567-1364.12093. Epub 2013 Oct 9.

43.

Keratin 19: a key role player in the invasion of human hepatocellular carcinomas.

Govaere O, Komuta M, Berkers J, Spee B, Janssen C, de Luca F, Katoonizadeh A, Wouters J, van Kempen LC, Durnez A, Verslype C, De Kock J, Rogiers V, van Grunsven LA, Topal B, Pirenne J, Vankelecom H, Nevens F, van den Oord J, Pinzani M, Roskams T.

Gut. 2014 Apr;63(4):674-85. doi: 10.1136/gutjnl-2012-304351. Epub 2013 Aug 19.

44.

Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals.

Rodrigues RM, De Kock J, Branson S, Vinken M, Meganathan K, Chaudhari U, Sachinidis A, Govaere O, Roskams T, De Boe V, Vanhaecke T, Rogiers V.

Stem Cells Dev. 2014 Jan 1;23(1):44-55. doi: 10.1089/scd.2013.0157. Epub 2013 Sep 21.

45.

Characterization of hepatic markers in human Wharton's Jelly-derived mesenchymal stem cells.

Buyl K, De Kock J, Najar M, Lagneaux L, Branson S, Rogiers V, Vanhaecke T.

Toxicol In Vitro. 2014 Feb;28(1):113-9. doi: 10.1016/j.tiv.2013.06.014. Epub 2013 Jun 29.

PMID:
23820183
46.

The "firing cannons" of Dipodascopsis uninucleata var. uninucleata.

Olivier AP, Swart CW, Pohl CH, van Wyk PW, Swart HC, Coetsee E, Schoombie SW, Smit J, Kock JL.

Can J Microbiol. 2013 Jun;59(6):413-6. doi: 10.1139/cjm-2013-0130. Epub 2013 Apr 25.

PMID:
23750956
47.

Gas bubble formation in the cytoplasm of a fermenting yeast.

Swart CW, Dithebe K, Pohl CH, Swart HC, Coetsee E, van Wyk PW, Swarts JC, Lodolo EJ, Kock JL.

FEMS Yeast Res. 2012 Nov;12(7):867-9. doi: 10.1111/j.1567-1364.12004.x. Epub 2012 Oct 1.

48.

Trichosporon vanderwaltii sp. nov., an asexual basidiomycetous yeast isolated from soil and beetles.

Motaung TE, Albertyn J, Kock JL, Lee CF, Suh SO, Blackwell M, Pohl CH.

Antonie Van Leeuwenhoek. 2013 Feb;103(2):313-9. doi: 10.1007/s10482-012-9811-2. Epub 2012 Sep 21.

PMID:
22996387
49.

Modifications in connexin expression in liver development and cancer.

Vinken M, De Kock J, Oliveira AG, Menezes GB, Cogliati B, Dagli ML, Vanhaecke T, Rogiers V.

Cell Commun Adhes. 2012 Aug;19(3-4):55-62. doi: 10.3109/15419061.2012.712576. Epub 2012 Sep 5. Review.

PMID:
22950570
50.

A liver-derived rat epithelial cell line from biliary origin acquires hepatic functions upon sequential exposure to hepatogenic growth factors and cytokines.

De Kock J, Snykers S, Branson S, Jagtap S, Gaspar JA, Sachinidis A, Vanhaecke T, Rogiers V.

Curr Med Chem. 2012;19(26):4523-33.

PMID:
22934771

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