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Items: 1 to 50 of 69

1.

Proteomic Analysis of the Maternal Preoptic Area in Rats.

Udvari EB, Völgyi K, Kékesi KA, Simon D, Hunyadi-Gulyás É, Dobolyi A.

Neurochem Res. 2019 Mar 7. doi: 10.1007/s11064-019-02755-y. [Epub ahead of print]

PMID:
30847857
2.

Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia.

Than NG, Romero R, Tarca AL, Kekesi KA, Xu Y, Xu Z, Juhasz K, Bhatti G, Leavitt RJ, Gelencser Z, Palhalmi J, Chung TH, Gyorffy BA, Orosz L, Demeter A, Szecsi A, Hunyadi-Gulyas E, Darula Z, Simor A, Eder K, Szabo S, Topping V, El-Azzamy H, LaJeunesse C, Balogh A, Szalai G, Land S, Torok O, Dong Z, Kovalszky I, Falus A, Meiri H, Draghici S, Hassan SS, Chaiworapongsa T, Krispin M, Knöfler M, Erez O, Burton GJ, Kim CJ, Juhasz G, Papp Z.

Front Immunol. 2018 Aug 8;9:1661. doi: 10.3389/fimmu.2018.01661. eCollection 2018.

3.

Local apoptotic-like mechanisms underlie complement-mediated synaptic pruning.

Györffy BA, Kun J, Török G, Bulyáki É, Borhegyi Z, Gulyássy P, Kis V, Szocsics P, Micsonai A, Matkó J, Drahos L, Juhász G, Kékesi KA, Kardos J.

Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6303-6308. doi: 10.1073/pnas.1722613115. Epub 2018 May 29.

4.

Early Presymptomatic Changes in the Proteome of Mitochondria-Associated Membrane in the APP/PS1 Mouse Model of Alzheimer's Disease.

Völgyi K, Badics K, Sialana FJ, Gulyássy P, Udvari EB, Kis V, Drahos L, Lubec G, Kékesi KA, Juhász G.

Mol Neurobiol. 2018 Oct;55(10):7839-7857. doi: 10.1007/s12035-018-0955-6. Epub 2018 Feb 22.

PMID:
29468564
5.

Chronic Cerebral Hypoperfusion Induced Synaptic Proteome Changes in the rat Cerebral Cortex.

Völgyi K, Gulyássy P, Todorov MI, Puska G, Badics K, Hlatky D, Kékesi KA, Nyitrai G, Czurkó A, Drahos L, Dobolyi A.

Mol Neurobiol. 2018 May;55(5):4253-4266. doi: 10.1007/s12035-017-0641-0. Epub 2017 Jun 15.

PMID:
28620701
6.

Synaptic proteome changes in the hypothalamus of mother rats.

Udvari EB, Völgyi K, Gulyássy P, Dimén D, Kis V, Barna J, Szabó ÉR, Lubec G, Juhász G, Kékesi KA, Dobolyi Á.

J Proteomics. 2017 Apr 21;159:54-66. doi: 10.1016/j.jprot.2017.03.006. Epub 2017 Mar 9.

PMID:
28286321
7.

The short- and long-term proteomic effects of sleep deprivation on the cortical and thalamic synapses.

Simor A, Györffy BA, Gulyássy P, Völgyi K, Tóth V, Todorov MI, Kis V, Borhegyi Z, Szabó Z, Janáky T, Drahos L, Juhász G, Kékesi KA.

Mol Cell Neurosci. 2017 Mar;79:64-80. doi: 10.1016/j.mcn.2017.01.002. Epub 2017 Jan 10.

PMID:
28087334
8.

Retino-cortical stimulus frequency-dependent gamma coupling: evidence and functional implications of oscillatory potentials.

Todorov MI, Kékesi KA, Borhegyi Z, Galambos R, Juhász G, Hudetz AG.

Physiol Rep. 2016 Oct;4(19). pii: e12986.

9.

Proteomic investigation of the prefrontal cortex in the rat clomipramine model of depression.

Gellén B, Völgyi K, Györffy BA, Darula Z, Hunyadi-Gulyás É, Baracskay P, Czurkó A, Hernádi I, Juhász G, Dobolyi Á, Kékesi KA.

J Proteomics. 2017 Feb 5;153:53-64. doi: 10.1016/j.jprot.2016.06.027. Epub 2016 Jun 29.

PMID:
27371348
10.

Maternal alterations in the proteome of the medial prefrontal cortex in rat.

Völgyi K, Udvari EB, Szabó ÉR, Györffy BA, Hunyadi-Gulyás É, Medzihradszky K, Juhász G, Kékesi KA, Dobolyi Á.

J Proteomics. 2017 Feb 5;153:65-77. doi: 10.1016/j.jprot.2016.05.013. Epub 2016 May 24.

PMID:
27233742
11.

Guanosine may increase absence epileptic activity by means of A2A adenosine receptors in Wistar Albino Glaxo Rijswijk rats.

Lakatos RK, Dobolyi Á, Todorov MI, Kékesi KA, Juhász G, Aleksza M, Kovács Z.

Brain Res Bull. 2016 Jun;124:172-81. doi: 10.1016/j.brainresbull.2016.05.001. Epub 2016 May 3.

PMID:
27154620
12.

Widespread alterations in the synaptic proteome of the adolescent cerebral cortex following prenatal immune activation in rats.

Györffy BA, Gulyássy P, Gellén B, Völgyi K, Madarasi D, Kis V, Ozohanics O, Papp I, Kovács P, Lubec G, Dobolyi Á, Kardos J, Drahos L, Juhász G, Kékesi KA.

Brain Behav Immun. 2016 Aug;56:289-309. doi: 10.1016/j.bbi.2016.04.002. Epub 2016 Apr 4.

PMID:
27058163
13.

Mitochondrial Proteome Changes Correlating with β-Amyloid Accumulation.

Völgyi K, Háden K, Kis V, Gulyássy P, Badics K, Györffy BA, Simor A, Szabó Z, Janáky T, Drahos L, Dobolyi Á, Penke B, Juhász G, Kékesi KA.

Mol Neurobiol. 2017 Apr;54(3):2060-2078. doi: 10.1007/s12035-015-9682-4. Epub 2016 Feb 24.

PMID:
26910821
14.

Modulatory effects of inosine, guanosine and uridine on lipopolysaccharide-evoked increase in spike-wave discharge activity in Wistar Albino Glaxo/Rijswijk rats.

Kovács Z, Kékesi KA, Juhász G, Dobolyi A.

Brain Res Bull. 2015 Sep;118:46-57. doi: 10.1016/j.brainresbull.2015.09.003. Epub 2015 Sep 10.

PMID:
26365718
15.

Absence epileptic activity changing effects of non-adenosine nucleoside inosine, guanosine and uridine in Wistar Albino Glaxo Rijswijk rats.

Kovács Z, Kékesi KA, Dobolyi Á, Lakatos R, Juhász G.

Neuroscience. 2015 Aug 6;300:593-608. doi: 10.1016/j.neuroscience.2015.05.054. Epub 2015 May 30.

PMID:
26037802
16.

Synaptic mitochondria: a brain mitochondria cluster with a specific proteome.

Völgyi K, Gulyássy P, Háden K, Kis V, Badics K, Kékesi KA, Simor A, Györffy B, Tóth EA, Lubec G, Juhász G, Dobolyi A.

J Proteomics. 2015 Apr 29;120:142-57. doi: 10.1016/j.jprot.2015.03.005. Epub 2015 Mar 14.

PMID:
25782751
17.

Effects of nucleosides on glia - neuron interactions open up new vistas in the development of more effective antiepileptic drugs.

Kovacs Z, Kardos J, Kekesi KA, Juhasz G, Lakatos R, Heja L.

Curr Med Chem. 2015;22(12):1500-14. Review.

PMID:
25666791
18.

Non-adenosine nucleoside inosine, guanosine and uridine as promising antiepileptic drugs: a summary of current literature.

Kovacs Z, Kekesi KA, Juhasz G, Barna J, Heja L, Lakatos R, Dobolyi A.

Mini Rev Med Chem. 2015;14(13):1033-42. Review.

PMID:
25382017
19.

Lipopolysaccharide induced increase in seizure activity in two animal models of absence epilepsy WAG/Rij and GAERS rats and Long Evans rats.

Kovács Z, Dobolyi A, Juhász G, Kékesi KA.

Brain Res Bull. 2014 May;104:7-18. doi: 10.1016/j.brainresbull.2014.03.003. Epub 2014 Apr 1.

PMID:
24704320
20.

Receptors of peptides as therapeutic targets in epilepsy research.

Dobolyi A, Kékesi KA, Juhász G, Székely AD, Lovas G, Kovács Z.

Curr Med Chem. 2014;21(6):764-87. Review.

PMID:
24251562
21.

The antiepileptic potential of nucleosides.

Kovács Z, Kékesi KA, Juhász G, Dobolyi Á.

Curr Med Chem. 2014;21(6):788-821. Review.

PMID:
24251559
22.

Brain protein expression changes in WAG/Rij rats, a genetic rat model of absence epilepsy after peripheral lipopolysaccharide treatment.

Györffy B, Kovács Z, Gulyássy P, Simor A, Völgyi K, Orbán G, Baracskay P, Szabó Z, Janáky T, Dobolyi A, Juhász G, Czurkó A, Kékesi KA.

Brain Behav Immun. 2014 Jan;35:86-95. doi: 10.1016/j.bbi.2013.09.001. Epub 2013 Sep 8.

PMID:
24021561
23.

5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications.

Kovács Z, Dobolyi A, Kékesi KA, Juhász G.

Curr Med Chem. 2013;20(34):4217-40. Review.

PMID:
23992313
24.

Altered functional protein networks in the prefrontal cortex and amygdala of victims of suicide.

Kékesi KA, Juhász G, Simor A, Gulyássy P, Szegő EM, Hunyadi-Gulyás E, Darula Z, Medzihradszky KF, Palkovits M, Penke B, Czurkó A.

PLoS One. 2012;7(12):e50532. doi: 10.1371/journal.pone.0050532. Epub 2012 Dec 6.

25.

Neonatal tricyclic antidepressant clomipramine treatment reduces the spike-wave discharge activity of the adult WAG/Rij rat.

Kovács Z, Czurkó A, Kékesi KA, Juhász G.

Brain Res Bull. 2012 Nov 1;89(3-4):102-7. doi: 10.1016/j.brainresbull.2012.07.010. Epub 2012 Aug 3.

PMID:
22884691
26.

Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and -2 Are essential for lectin pathway activation and reveal structural plasticity of MASP-2.

Héja D, Harmat V, Fodor K, Wilmanns M, Dobó J, Kékesi KA, Závodszky P, Gál P, Pál G.

J Biol Chem. 2012 Jun 8;287(24):20290-300. doi: 10.1074/jbc.M112.354332. Epub 2012 Apr 16.

27.

Crystal structure of the S100A4-nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism.

Kiss B, Duelli A, Radnai L, Kékesi KA, Katona G, Nyitray L.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6048-53. doi: 10.1073/pnas.1114732109. Epub 2012 Mar 28.

28.

Thalamic Gap Junctions Control Local Neuronal Synchrony and Influence Macroscopic Oscillation Amplitude during EEG Alpha Rhythms.

Hughes SW, Lőrincz ML, Blethyn K, Kékesi KA, Juhász G, Turmaine M, Parnavelas JG, Crunelli V.

Front Psychol. 2011 Aug 22;2:193. doi: 10.3389/fpsyg.2011.00193. eCollection 2011.

29.

Doxycycline could aggravate the absence-like epileptic seizures of WAG/Rij rats via matrix metalloproteinase inhibition.

Kovács Z, Kékesi KA, Baracskay P, Juhász G, Czurkó A.

Neurochem Int. 2011 Oct;59(5):563-6. doi: 10.1016/j.neuint.2011.06.016. Epub 2011 Jun 28.

PMID:
21740942
30.

Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1.

Dobó J, Major B, Kékesi KA, Szabó I, Megyeri M, Hajela K, Juhász G, Závodszky P, Gál P.

PLoS One. 2011;6(5):e20036. doi: 10.1371/journal.pone.0020036. Epub 2011 May 23.

31.

Intracerebroventricularly administered lipopolysaccharide enhances spike-wave discharges in freely moving WAG/Rij rats.

Kovács Z, Czurkó A, Kékesi KA, Juhász G.

Brain Res Bull. 2011 Jul 15;85(6):410-6. doi: 10.1016/j.brainresbull.2011.05.003. Epub 2011 May 17.

PMID:
21619914
32.

High affinity small protein inhibitors of human chymotrypsin C (CTRC) selected by phage display reveal unusual preference for P4' acidic residues.

Szabó A, Héja D, Szakács D, Zboray K, Kékesi KA, Radisky ES, Sahin-Tóth M, Pál G.

J Biol Chem. 2011 Jun 24;286(25):22535-45. doi: 10.1074/jbc.M111.235754. Epub 2011 Apr 22.

33.

Ex vivo soft-laser treatment inhibits the synovial expression of vimentin and α-enolase, potential autoantigens in rheumatoid arthritis.

Bálint G, Barabás K, Zeitler Z, Bakos J, Kékesi KA, Pethes A, Nagy E, Lakatos T, Bálint PV, Szekanecz Z.

Phys Ther. 2011 May;91(5):665-74. doi: 10.2522/ptj.20100065. Epub 2011 Mar 24.

PMID:
21436364
34.

Area, age and gender dependence of the nucleoside system in the brain: a review of current literature.

Kovács Z, Juhász G, Palkovits M, Dobolyi A, Kékesi KA.

Curr Top Med Chem. 2011;11(8):1012-33. Review.

PMID:
21401498
35.

The effect of intraperitoneally administered dimethyl sulfoxide on absence-like epileptic activity of freely moving WAG/Rij rats.

Kovács Z, Czurkó A, Kékesi KA, Juhász G.

J Neurosci Methods. 2011 Apr 15;197(1):133-6. doi: 10.1016/j.jneumeth.2011.02.005. Epub 2011 Feb 12.

PMID:
21320528
36.

Effects of estrogen on beta-amyloid-induced cholinergic cell death in the nucleus basalis magnocellularis.

Szego EM, Csorba A, Janáky T, Kékesi KA, Abrahám IM, Mórotz GM, Penke B, Palkovits M, Murvai U, Kellermayer MS, Kardos J, Juhász GD.

Neuroendocrinology. 2011;93(2):90-105. doi: 10.1159/000321119. Epub 2010 Oct 9.

PMID:
20938166
37.

Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation.

Kocsis A, Kékesi KA, Szász R, Végh BM, Balczer J, Dobó J, Závodszky P, Gál P, Pál G.

J Immunol. 2010 Oct 1;185(7):4169-78. doi: 10.4049/jimmunol.1001819. Epub 2010 Sep 3.

38.

Different electrophysiological actions of 24- and 72-hour aggregated amyloid-beta oligomers on hippocampal field population spike in both anesthetized and awake rats.

Orbán G, Völgyi K, Juhász G, Penke B, Kékesi KA, Kardos J, Czurkó A.

Brain Res. 2010 Oct 1;1354:227-35. doi: 10.1016/j.brainres.2010.07.061. Epub 2010 Jul 24.

PMID:
20659435
39.

Clomipramine increases the incidence and duration of spike-wave discharges in freely moving WAG/Rij rats.

Kovács Z, Czurkó A, Kékesi KA, Juhász G.

Epilepsy Res. 2010 Jun;90(1-2):167-70. doi: 10.1016/j.eplepsyres.2010.02.011. Epub 2010 Mar 17.

PMID:
20299188
40.

Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r.

Major B, Kardos J, Kékesi KA, Lorincz Z, Závodszky P, Gál P.

J Biol Chem. 2010 Apr 16;285(16):11863-9. doi: 10.1074/jbc.M109.098541. Epub 2010 Feb 23.

41.

A mouse model of anxiety molecularly characterized by altered protein networks in the brain proteome.

Szego EM, Janáky T, Szabó Z, Csorba A, Kompagne H, Müller G, Lévay G, Simor A, Juhász G, Kékesi KA.

Eur Neuropsychopharmacol. 2010 Feb;20(2):96-111. doi: 10.1016/j.euroneuro.2009.11.003. Epub 2009 Dec 16.

PMID:
20015620
42.

Estrogen regulates cytoskeletal flexibility, cellular metabolism and synaptic proteins: A proteomic study.

Szego EM, Kékesi KA, Szabó Z, Janáky T, Juhász GD.

Psychoneuroendocrinology. 2010 Jul;35(6):807-19. doi: 10.1016/j.psyneuen.2009.11.006. Epub 2009 Dec 14.

PMID:
20005634
43.

Status epilepticus affects the gigantocellular network of the pontine reticular formation.

Baracskay P, Kiglics V, Kékesi KA, Juhász G, Czurkó A.

BMC Neurosci. 2009 Nov 13;10:133. doi: 10.1186/1471-2202-10-133.

44.

Nucleoside map of the human central nervous system.

Kovács Z, Dobolyi A, Juhász G, Kékesi KA.

Neurochem Res. 2010 Mar;35(3):452-64. doi: 10.1007/s11064-009-0080-z. Epub 2009 Oct 24.

PMID:
19856099
45.

Gender- and age-dependent changes in nucleoside levels in the cerebral cortex and white matter of the human brain.

Kovács Z, Juhász G, Dobolyi A, Bobest M, Papp V, Takáts L, Kékesi KA.

Brain Res Bull. 2010 Apr 5;81(6):579-84. doi: 10.1016/j.brainresbull.2009.10.010. Epub 2009 Oct 21.

PMID:
19853023
46.

Glutamate uptake triggers transporter-mediated GABA release from astrocytes.

Héja L, Barabás P, Nyitrai G, Kékesi KA, Lasztóczi B, Toke O, Tárkányi G, Madsen K, Schousboe A, Dobolyi A, Palkovits M, Kardos J.

PLoS One. 2009 Sep 24;4(9):e7153. doi: 10.1371/journal.pone.0007153.

47.

Temporal framing of thalamic relay-mode firing by phasic inhibition during the alpha rhythm.

Lorincz ML, Kékesi KA, Juhász G, Crunelli V, Hughes SW.

Neuron. 2009 Sep 10;63(5):683-96. doi: 10.1016/j.neuron.2009.08.012.

48.

Novel modes of rhythmic burst firing at cognitively-relevant frequencies in thalamocortical neurons.

Hughes SW, Errington A, Lorincz ML, Kékesi KA, Juhász G, Orbán G, Cope DW, Crunelli V.

Brain Res. 2008 Oct 15;1235:12-20. doi: 10.1016/j.brainres.2008.06.029. Epub 2008 Jun 19. Review.

49.

Concentration of nucleosides and related compounds in cerebral and cerebellar cortical areas and white matter of the human brain.

Kékesi KA, Kovács Z, Szilágyi N, Bobest M, Szikra T, Dobolyi A, Juhász G, Palkovits M.

Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):833-44. Epub 2006 Aug 1.

PMID:
16897364
50.

Extracellular level of GABA and Glu: in vivo microdialysis-HPLC measurements.

Nyitrai G, Kékesi KA, Juhász G.

Curr Top Med Chem. 2006;6(10):935-40. Review.

PMID:
16787267

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