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Items: 1 to 50 of 77

1.

Chrysin ameliorates nonalcoholic fatty liver disease in rats.

Pai SA, Munshi RP, Panchal FH, Gaur IS, Juvekar AR.

Naunyn Schmiedebergs Arch Pharmacol. 2019 Aug 1. doi: 10.1007/s00210-019-01705-3. [Epub ahead of print]

PMID:
31372694
2.

Plumbagin reduces obesity and nonalcoholic fatty liver disease induced by fructose in rats through regulation of lipid metabolism, inflammation and oxidative stress.

Pai SA, Munshi RP, Panchal FH, Gaur IS, Mestry SN, Gursahani MS, Juvekar AR.

Biomed Pharmacother. 2019 Mar;111:686-694. doi: 10.1016/j.biopha.2018.12.139. Epub 2019 Jan 3.

3.

Imperatorin ameliorates lipopolysaccharide induced memory deficit by mitigating proinflammatory cytokines, oxidative stress and modulating brain-derived neurotropic factor.

Chowdhury AA, Gawali NB, Shinde P, Munshi R, Juvekar AR.

Cytokine. 2018 Oct;110:78-86. doi: 10.1016/j.cyto.2018.04.018. Epub 2018 Apr 26.

PMID:
29705395
4.

Plumbagin exerts antiobesity effects through inhibition of pancreatic lipase and adipocyte differentiation.

Pai SA, Martis EAF, Joshi SG, Munshi RP, Juvekar AR.

Phytother Res. 2018 Aug;32(8):1631-1635. doi: 10.1002/ptr.6085. Epub 2018 Apr 19.

PMID:
29672969
5.

Punica granatum improves renal function in gentamicin-induced nephropathy in rats via attenuation of oxidative stress.

Mestry SN, Gawali NB, Pai SA, Gursahani MS, Dhodi JB, Munshi R, Juvekar AR.

J Ayurveda Integr Med. 2018 Mar 16. pii: S0975-9476(17)30323-6. doi: 10.1016/j.jaim.2017.09.006. [Epub ahead of print]

6.

In vitro antiglycating effect and in vivo neuroprotective activity of Trigonelline in d-galactose induced cognitive impairment.

Chowdhury AA, Gawali NB, Bulani VD, Kothavade PS, Mestry SN, Deshpande PS, Juvekar AR.

Pharmacol Rep. 2018 Apr;70(2):372-377. doi: 10.1016/j.pharep.2017.09.006. Epub 2017 Sep 28.

PMID:
29477946
7.

Trigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice.

Chowdhury AA, Gawali NB, Munshi R, Juvekar AR.

Metab Brain Dis. 2018 Jun;33(3):681-691. doi: 10.1007/s11011-017-0147-5. Epub 2017 Dec 26.

PMID:
29277879
8.

Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells.

Shaik AB, Rao GK, Kumar GB, Patel N, Reddy VS, Khan I, Routhu SR, Kumar CG, Veena I, Chandra Shekar K, Barkume M, Jadhav S, Juvekar A, Kode J, Pal-Bhadra M, Kamal A.

Eur J Med Chem. 2017 Oct 20;139:305-324. doi: 10.1016/j.ejmech.2017.07.056. Epub 2017 Jul 25.

PMID:
28803046
9.

Attenuation of diabetic nephropathy in streptozotocin-induced diabetic rats by Punica granatum Linn. leaves extract.

Mestry SN, Dhodi JB, Kumbhar SB, Juvekar AR.

J Tradit Complement Med. 2016 Jul 13;7(3):273-280. doi: 10.1016/j.jtcme.2016.06.008. eCollection 2017 Jul.

10.

Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway.

Gawali NB, Bulani VD, Gursahani MS, Deshpande PS, Kothavade PS, Juvekar AR.

Brain Res. 2017 May 15;1663:66-77. doi: 10.1016/j.brainres.2017.03.004. Epub 2017 Mar 14.

PMID:
28302445
11.

Neuroprotective effect of curcumin as evinced by abrogation of rotenone-induced motor deficits, oxidative and mitochondrial dysfunctions in mouse model of Parkinson's disease.

Khatri DK, Juvekar AR.

Pharmacol Biochem Behav. 2016 Nov - Dec;150-151:39-47. doi: 10.1016/j.pbb.2016.09.002. Epub 2016 Sep 9.

PMID:
27619637
12.

Agmatine ameliorates lipopolysaccharide induced depressive-like behaviour in mice by targeting the underlying inflammatory and oxido-nitrosative mediators.

Gawali NB, Bulani VD, Chowdhury AA, Deshpande PS, Nagmoti DM, Juvekar AR.

Pharmacol Biochem Behav. 2016 Oct;149:1-8. doi: 10.1016/j.pbb.2016.07.004. Epub 2016 Jul 21.

PMID:
27453424
13.

Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion.

Juvekar A, Hu H, Yadegarynia S, Lyssiotis CA, Ullas S, Lien EC, Bellinger G, Son J, Hok RC, Seth P, Daly MB, Kim B, Scully R, Asara JM, Cantley LC, Wulf GM.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4338-47. doi: 10.1073/pnas.1522223113. Epub 2016 Jul 8.

14.

Kinetics of Inhibition of Monoamine Oxidase Using Curcumin and Ellagic Acid.

Khatri DK, Juvekar AR.

Pharmacogn Mag. 2016 May;12(Suppl 2):S116-20. doi: 10.4103/0973-1296.182168. Epub 2016 May 11.

15.

Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer.

Lien EC, Lyssiotis CA, Juvekar A, Hu H, Asara JM, Cantley LC, Toker A.

Nat Cell Biol. 2016 May;18(5):572-8. doi: 10.1038/ncb3341. Epub 2016 Apr 18.

16.

Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton.

Hu H, Juvekar A, Lyssiotis CA, Lien EC, Albeck JG, Oh D, Varma G, Hung YP, Ullas S, Lauring J, Seth P, Lundquist MR, Tolan DR, Grant AK, Needleman DJ, Asara JM, Cantley LC, Wulf GM.

Cell. 2016 Jan 28;164(3):433-46. doi: 10.1016/j.cell.2015.12.042.

17.

Involvement of nitric oxide in anticompulsive-like effect of agmatine on marble-burying behaviour in mice.

Gawali NB, Chowdhury AA, Kothavade PS, Bulani VD, Nagmoti DM, Juvekar AR.

Eur J Pharmacol. 2016 Jan 5;770:165-71. doi: 10.1016/j.ejphar.2015.11.044. Epub 2015 Nov 22.

PMID:
26593708
18.

Therapeutic Effect of Saponin Rich Fraction of Achyranthes aspera Linn. on Adjuvant-Induced Arthritis in Sprague-Dawley Rats.

Kothavade PS, Bulani VD, Nagmoti DM, Deshpande PS, Gawali NB, Juvekar AR.

Autoimmune Dis. 2015;2015:943645. doi: 10.1155/2015/943645. Epub 2015 Jul 26.

19.

Arzanol, a potent mPGES-1 inhibitor: novel anti-inflammatory agent.

Kothavade PS, Nagmoti DM, Bulani VD, Juvekar AR.

ScientificWorldJournal. 2013 Oct 1;2013:986429. doi: 10.1155/2013/986429. eCollection 2013. Review.

20.

Remarkable anti-breast cancer activity of ferrocene tagged multi-functionalized 1,4-dihydropyrimidines.

Jadhav J, Juvekar A, Kurane R, Khanapure S, Salunkhe R, Rashinkar G.

Eur J Med Chem. 2013 Jul;65:232-9. doi: 10.1016/j.ejmech.2013.04.021. Epub 2013 Apr 28.

PMID:
23711834
21.

Closing escape routes: inhibition of IL-8 signaling enhances the anti-tumor efficacy of PI3K inhibitors.

Juvekar A, Wulf GM.

Breast Cancer Res. 2013 Apr 8;15(2):308. doi: 10.1186/bcr3400.

22.
23.

Evaluation of anti-inflammatory activity of Typha angustifolia pollen grains extracts in experimental animals.

Varpe SS, Juvekar AR, Bidikar MP, Juvekar PR.

Indian J Pharmacol. 2012 Nov-Dec;44(6):788-91. doi: 10.4103/0253-7613.103303.

24.

Gastroprotective Effect of Oxalis corniculata (Whole Plant) on Experimentally Induced Gastric Ulceration in Wistar Rats.

Sakat SS, Tupe P, Juvekar A.

Indian J Pharm Sci. 2012 Jan;74(1):48-53. doi: 10.4103/0250-474X.102543.

25.

Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer.

Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmañà J, Rajendran A, Papa A, Spencer K, Lyssiotis CA, Nardella C, Pandolfi PP, Baselga J, Scully R, Asara JM, Cantley LC, Wulf GM.

Cancer Discov. 2012 Nov;2(11):1048-63. doi: 10.1158/2159-8290.CD-11-0336. Epub 2012 Aug 22.

26.

Chromatin immunoprecipitation analysis of NFκB transcriptional regulation by nuclear IκBα in human macrophages.

Ramaswami S, Manna S, Juvekar A, Kennedy S, Vancura A, Vancurova I.

Methods Mol Biol. 2012;809:121-34. doi: 10.1007/978-1-61779-376-9_8.

PMID:
22113272
27.

Electrophoretic mobility shift assay analysis of NFκB transcriptional regulation by nuclear IκBα.

Juvekar A, Ramaswami S, Manna S, Chang TP, Zubair A, Vancurova I.

Methods Mol Biol. 2012;809:49-62. doi: 10.1007/978-1-61779-376-9_3.

PMID:
22113267
28.

Carbohydrate-conjugate heterobimetallic complexes: synthesis, DNA binding studies, artificial nuclease activity and in vitro cytotoxicity.

Tabassum S, Khan RA, Arjmand F, Aziz M, Juvekar AS, Zingde SM.

Carbohydr Res. 2011 Dec 27;346(18):2886-95. doi: 10.1016/j.carres.2011.10.010. Epub 2011 Oct 15.

PMID:
22055812
29.

Synthesis of aryl-substituted naphthalene-linked pyrrolobenzodiazepine conjugates as potential anticancer agents with apoptosis-inducing ability.

Kamal A, Reddy MK, Ramaiah MJ, Srikanth YV, Rajender, Reddy VS, Kumar GB, Pushpavalli SN, Bag I, Juvekar A, Sen S, Zingde SM, Pal-Bhadra M.

ChemMedChem. 2011 Sep 5;6(9):1665-79. doi: 10.1002/cmdc.201100207. Epub 2011 Jul 5.

PMID:
21732540
31.

Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents.

Kamal A, Kumar BA, Suresh P, Juvekar A, Zingde S.

Bioorg Med Chem. 2011 May 1;19(9):2975-9. doi: 10.1016/j.bmc.2011.03.030. Epub 2011 Mar 21.

PMID:
21489802
32.

An evaluation of the antidiabetic effects of Elaeocarpus ganitrus in experimental animals.

Hule AK, Shah AS, Gambhire MN, Juvekar AR.

Indian J Pharmacol. 2011 Feb;43(1):56-9. doi: 10.4103/0253-7613.75671.

33.
34.

Comparative Study of Erythrina indica Lam. (Febaceae) Leaves Extracts for Antioxidant Activity.

Sakat S, Juvekar A.

J Young Pharm. 2010 Jan;2(1):63-7. doi: 10.4103/0975-1483.62216.

35.

Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL.

Juvekar A, Manna S, Ramaswami S, Chang TP, Vu HY, Ghosh CC, Celiker MY, Vancurova I.

Mol Cancer Res. 2011 Feb;9(2):183-94. doi: 10.1158/1541-7786.MCR-10-0368. Epub 2011 Jan 11.

36.

Synthesis of carbohydrate-conjugate heterobimetallic Cu(II)-Sn(2)(IV) and Zn(II)-Sn(2)(IV) complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity.

Tabassum S, Khan RA, Arjmand F, Juvekar AS, Zingde SM.

Eur J Med Chem. 2010 Nov;45(11):4797-806. doi: 10.1016/j.ejmech.2010.07.046. Epub 2010 Aug 14.

PMID:
20813437
37.

Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole-pyrrolobenzodiazepine conjugates.

Kamal A, Dastagiri D, Ramaiah MJ, Bharathi EV, Reddy JS, Balakishan G, Sarma P, Pushpavalli SN, Pal-Bhadra M, Juvekar A, Sen S, Zingde S.

Bioorg Med Chem. 2010 Sep 15;18(18):6666-77. doi: 10.1016/j.bmc.2010.07.067. Epub 2010 Aug 1.

PMID:
20732817
38.

In vitro and in vivo immunostimulatory activity of Woodfordia fruticosa flowers on non-specific immunity.

Shah AS, Juvekar AR.

Pharm Biol. 2010 Sep;48(9):1066-72. doi: 10.3109/13880200903490497.

PMID:
20731559
39.

Gene-specific repression of proinflammatory cytokines in stimulated human macrophages by nuclear IκBα.

Ghosh CC, Ramaswami S, Juvekar A, Vu HY, Galdieri L, Davidson D, Vancurova I.

J Immunol. 2010 Sep 15;185(6):3685-93. doi: 10.4049/jimmunol.0902230. Epub 2010 Aug 9.

40.

Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole-pyrrolo[2,1-c][1,4]benzodiazepine conjugates.

Kamal A, Reddy KS, Khan MN, Shetti RV, Ramaiah MJ, Pushpavalli SN, Srinivas C, Pal-Bhadra M, Chourasia M, Sastry GN, Juvekar A, Zingde S, Barkume M.

Bioorg Med Chem. 2010 Jul 1;18(13):4747-61. doi: 10.1016/j.bmc.2010.05.007. Epub 2010 May 7.

PMID:
20627593
41.

Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents.

Kamal A, Reddy JS, Ramaiah MJ, Dastagiri D, Bharathi EV, Azhar MA, Sultana F, Pushpavalli SN, Pal-Bhadra M, Juvekar A, Sen S, Zingde S.

Eur J Med Chem. 2010 Sep;45(9):3924-37. doi: 10.1016/j.ejmech.2010.05.047. Epub 2010 May 31.

PMID:
20557981
42.

Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates.

Kamal A, Vijaya Bharathi E, Janaki Ramaiah M, Surendranadha Reddy J, Dastagiri D, Viswanath A, Sultana F, Pushpavalli SN, Pal-Bhadra M, Juvekar A, Sen S, Zingde S.

Bioorg Med Chem Lett. 2010 Jun 1;20(11):3310-3. doi: 10.1016/j.bmcl.2010.04.037. Epub 2010 Apr 14.

PMID:
20444601
43.

Optimization of xylanase production from Aspergillus foetidus MTCC 4898 by solid state fermentation using statistical methods.

Valte RD, Borude PC, Hule AK, Juvekar AR.

J Gen Appl Microbiol. 2010 Feb;56(1):75-80. No abstract available.

44.

Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents.

Kamal A, Vijaya Bharathi E, Janaki Ramaiah M, Dastagiri D, Surendranadha Reddy J, Viswanath A, Sultana F, Pushpavalli SN, Pal-Bhadra M, Srivastava HK, Narahari Sastry G, Juvekar A, Sen S, Zingde S.

Bioorg Med Chem. 2010 Jan 15;18(2):526-42. doi: 10.1016/j.bmc.2009.12.015. Epub 2009 Dec 11.

PMID:
20031423
45.

Effect of Alstonia scholaris (Linn.) R. Br. on stress and cognition in mice.

Kulkarni MP, Juvekar AR.

Indian J Exp Biol. 2009 Jan;47(1):47-52.

PMID:
19317351
46.
47.

Immunomodulatory activity of methanolic extract of Murraya koenigii (L) Spreng. leaves.

Shah AS, Wakade AS, Juvekar AR.

Indian J Exp Biol. 2008 Jul;46(7):505-9.

PMID:
18807753
48.

Synthesis, DNA-binding ability and evaluation of antitumour activity of triazolo[1,2,4]benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates.

Kamal A, Khan MN, Srikanth YV, Reddy KS, Juvekar A, Sen S, Kurian N, Zingde S.

Bioorg Med Chem. 2008 Aug 15;16(16):7804-10. doi: 10.1016/j.bmc.2008.06.056. Epub 2008 Jul 3.

PMID:
18657979
49.

Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide conjugates linked through piperazine side-armed alkane spacers.

Kamal A, Ramu R, Tekumalla V, Khanna GB, Barkume MS, Juvekar AS, Zingde SM.

Bioorg Med Chem. 2008 Aug 1;16(15):7218-24. doi: 10.1016/j.bmc.2008.06.034. Epub 2008 Jun 25.

PMID:
18656370
50.

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