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Items: 1 to 50 of 227

1.

Streamlining drug discovery assays for cardiovascular disease using zebrafish.

Pott A, Rottbauer W, Just S.

Expert Opin Drug Discov. 2020 Jan;15(1):27-37. doi: 10.1080/17460441.2020.1671351. Epub 2019 Oct 1.

PMID:
31570020
2.

Machine Learning Methods for Automated Quantification of Ventricular Dimensions.

Schutera M, Just S, Gierten J, Mikut R, Reischl M, Pylatiuk C.

Zebrafish. 2019 Dec;16(6):542-545. doi: 10.1089/zeb.2019.1754. Epub 2019 Oct 3.

PMID:
31536467
3.

A diagnosis of von Willebrand disease despite normal test results for factor VIII and von Willebrand factor antigen and activity.

Motum P, Just S, Zebeljan D, Nicholls C, Kershaw G, Oliver S, Mohammed S, Favaloro EJ.

Am J Hematol. 2019 Dec;94(12):1425-1432. doi: 10.1002/ajh.25618. Epub 2019 Aug 30. No abstract available.

PMID:
31423628
4.

Six-month prospective trial in early and long-standing rheumatoid arthritis: evaluating disease activity in the wrist through sequential synovial histopathological analysis, RAMRIS magnetic resonance score and EULAR-OMERACT ultrasound score.

Just SA, Nielsen C, Werlinrud JC, Larsen PV, Klinkby CS, Schrøder HD, Humby F, Torfing T, Lindegaard H.

RMD Open. 2019 Jul 8;5(2):e000951. doi: 10.1136/rmdopen-2019-000951. eCollection 2019.

5.

Functional Characterization of Rare Variants in the SHOX2 Gene Identified in Sinus Node Dysfunction and Atrial Fibrillation.

Hoffmann S, Paone C, Sumer SA, Diebold S, Weiss B, Roeth R, Clauss S, Klier I, Kääb S, Schulz A, Wild PS, Ghrib A, Zeller T, Schnabel RB, Just S, Rappold GA.

Front Genet. 2019 Jul 11;10:648. doi: 10.3389/fgene.2019.00648. eCollection 2019.

6.

The in vitro effect of antirheumatic drugs on platelet function.

Nielsen CB, Nielsen C, Nybo M, Just SA, Vinholt PJ.

Platelets. 2019 May 2:1-10. doi: 10.1080/09537104.2019.1609665. [Epub ahead of print]

PMID:
31046542
7.

Neural networks for automatic scoring of arthritis disease activity on ultrasound images.

Andersen JKH, Pedersen JS, Laursen MS, Holtz K, Grauslund J, Savarimuthu TR, Just SA.

RMD Open. 2019 Mar 30;5(1):e000891. doi: 10.1136/rmdopen-2018-000891. eCollection 2019.

8.

Targeted deletion of Tcf7l2 in adipocytes promotes adipocyte hypertrophy and impaired glucose metabolism.

Geoghegan G, Simcox J, Seldin MM, Parnell TJ, Stubben C, Just S, Begaye L, Lusis AJ, Villanueva CJ.

Mol Metab. 2019 Jun;24:44-63. doi: 10.1016/j.molmet.2019.03.003. Epub 2019 Mar 14.

9.

OTUB1 inhibits CNS autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes.

Wang X, Mulas F, Yi W, Brunn A, Nishanth G, Just S, Waisman A, Brück W, Deckert M, Schlüter D.

EMBO J. 2019 May 15;38(10). pii: e100947. doi: 10.15252/embj.2018100947. Epub 2019 Apr 3.

PMID:
30944096
10.

Correction to: Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups.

Najm A, Le Goff B, Orr C, Thurlings R, Cañete JD, Humby F, Alivernini S, Manzo A, Just SA, Romão VC, Krenn V, Müller-Ladner U, Addimanda O, Tas SW, Stoenoiu M, de Bellefon LM, Durez P, Strand V, Wechalekar MD, Fonseca JE, Lauwerys B, Fearon U, Veale DJ; EULAR Synovitis Study Group and OMERACT Synovial Tissue Special Interest Group.

Arthritis Res Ther. 2018 Dec 19;20(1):282. doi: 10.1186/s13075-018-1795-5.

11.

Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups.

Najm A, Le Goff B, Orr C, Thurlings R, Cañete JD, Humby F, Alivernini S, Manzo A, Just SA, Romão VC, Krenn V, Müller-Ladner U, Addimanda O, Tas SW, Stoenoiu M, Meric de Bellefon L, Durez P, Strand V, Wechalekar MD, Fonseca JE, Lauwerys B, Fearon U, Veale DJ; EULAR Synovitis Study Group and OMERACT Synovial Tissue Special Interest Group.

Arthritis Res Ther. 2018 Dec 3;20(1):265. doi: 10.1186/s13075-018-1762-1. Erratum in: Arthritis Res Ther. 2018 Dec 19;20(1):282.

12.

Patient-reported outcomes and safety in patients undergoing synovial biopsy: comparison of ultrasound-guided needle biopsy, ultrasound-guided portal and forceps and arthroscopic-guided synovial biopsy techniques in five centres across Europe.

Just SA, Humby F, Lindegaard H, Meric de Bellefon L, Durez P, Vieira-Sousa E, Teixeira R, Stoenoiu M, Werlinrud J, Rosmark S, Larsen PV, Pratt A, Choy E, Gendi N, Buch MH, Edwards CJ, Taylor PC, McInnes IB, Fonseca JE, Pitzalis C, Filer A.

RMD Open. 2018 Oct 26;4(2):e000799. doi: 10.1136/rmdopen-2018-000799. eCollection 2018.

13.

Semantic Multi-Classifier Systems Identify Predictive Processes in Heart Failure Models across Species.

Lausser L, Siegle L, Rottbauer W, Frank D, Just S, Kestler HA.

Biomolecules. 2018 Nov 26;8(4). pii: E158. doi: 10.3390/biom8040158.

14.

Therapeutic Chemical Screen Identifies Phosphatase Inhibitors to Reconstitute PKB Phosphorylation and Cardiac Contractility in ILK-Deficient Zebrafish.

Pott A, Shahid M, Köhler D, Pylatiuk C, Weinmann K, Just S, Rottbauer W.

Biomolecules. 2018 Nov 19;8(4). pii: E153. doi: 10.3390/biom8040153.

15.

Amyloid precursor protein-fragments-containing inclusions in cardiomyocytes with basophilic degeneration and its association with cerebral amyloid angiopathy and myocardial fibrosis.

Krämer LM, Brettschneider J, Lennerz JK, Walcher D, Fang L, Rosenbohm A, Balakrishnan K, Benckendorff J, Möller P, Just S, Willem M, Ludolph AC, Thal DR.

Sci Rep. 2018 Nov 9;8(1):16594. doi: 10.1038/s41598-018-34808-7.

16.

Invited Review Article: Multi-tip scanning tunneling microscopy: Experimental techniques and data analysis.

Voigtländer B, Cherepanov V, Korte S, Leis A, Cuma D, Just S, Lüpke F.

Rev Sci Instrum. 2018 Oct;89(10):101101. doi: 10.1063/1.5042346.

PMID:
30399776
17.

Metabolic Profiling of Glucocorticoid Deficiency: A "Fishing" Expedition.

Pott A, Just S.

EBioMedicine. 2018 Nov;37:27-28. doi: 10.1016/j.ebiom.2018.10.058. Epub 2018 Oct 31. No abstract available.

18.

The gut microbiota drives the impact of bile acids and fat source in diet on mouse metabolism.

Just S, Mondot S, Ecker J, Wegner K, Rath E, Gau L, Streidl T, Hery-Arnaud G, Schmidt S, Lesker TR, Bieth V, Dunkel A, Strowig T, Hofmann T, Haller D, Liebisch G, Gérard P, Rohn S, Lepage P, Clavel T.

Microbiome. 2018 Aug 2;6(1):134. doi: 10.1186/s40168-018-0510-8.

19.

Mediator complex subunit Med12 regulates cardiac jelly development and AV valve formation in zebrafish.

Segert J, Schneider I, Berger IM, Rottbauer W, Just S.

Prog Biophys Mol Biol. 2018 Oct;138:20-31. doi: 10.1016/j.pbiomolbio.2018.07.010. Epub 2018 Jul 20.

PMID:
30036562
20.

Surgical repair of an uncontrolled thrombus caused by the Watchman device.

Gyoten T, Grimmig O, Just S, Fritzsche D.

Interact Cardiovasc Thorac Surg. 2019 Jan 1;28(1):164-166. doi: 10.1093/icvts/ivy227.

PMID:
30032265
21.

Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS.

Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, Weishaupt JH.

Cell Mol Life Sci. 2018 Dec;75(23):4301-4319. doi: 10.1007/s00018-018-2873-1. Epub 2018 Jul 20.

PMID:
30030593
22.

Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo.

Kustermann M, Manta L, Paone C, Kustermann J, Lausser L, Wiesner C, Eichinger L, Clemen CS, Schröder R, Kestler HA, Sandri M, Rottbauer W, Just S.

Autophagy. 2018;14(11):1911-1927. doi: 10.1080/15548627.2018.1491491. Epub 2018 Aug 16.

23.

Genetics of Cardiovascular Disease: Fishing for Causality.

Paone C, Diofano F, Park DD, Rottbauer W, Just S.

Front Cardiovasc Med. 2018 Jun 1;5:60. doi: 10.3389/fcvm.2018.00060. eCollection 2018. Review.

24.

The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.

Silbernagel N, Walecki M, Schäfer MK, Kessler M, Zobeiri M, Rinné S, Kiper AK, Komadowski MA, Vowinkel KS, Wemhöner K, Fortmüller L, Schewe M, Dolga AM, Scekic-Zahirovic J, Matschke LA, Culmsee C, Baukrowitz T, Monassier L, Ullrich ND, Dupuis L, Just S, Budde T, Fabritz L, Decher N.

FASEB J. 2018 Nov;32(11):6159-6173. doi: 10.1096/fj.201800246R. Epub 2018 Jun 7.

25.

Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish.

Pott A, Bock S, Berger IM, Frese K, Dahme T, Keßler M, Rinné S, Decher N, Just S, Rottbauer W.

J Mol Cell Cardiol. 2018 Jul;120:42-52. doi: 10.1016/j.yjmcc.2018.05.005. Epub 2018 May 8.

PMID:
29750993
26.

A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations.

Keßler M, Kieltsch A, Kayvanpour E, Katus HA, Schoser B, Schessl J, Just S, Rottbauer W.

Neuromuscul Disord. 2018 Jun;28(6):521-531. doi: 10.1016/j.nmd.2018.03.001. Epub 2018 Mar 15.

27.

[Substance Abuse Poisoning Reported to the Poisons Information Centre Erfurt from 2002 to 2016].

Gollmann M, Frimlova G, Just S, Liebetrau G, Prasa D, Stürzebecher A, Deters M.

Gesundheitswesen. 2019 May;81(5):397-404. doi: 10.1055/a-0592-6674. Epub 2018 May 2. German.

PMID:
29719914
28.

New perspectives: systems medicine in cardiovascular disease.

Kramer F, Just S, Zeller T.

BMC Syst Biol. 2018 Apr 25;12(1):57. doi: 10.1186/s12918-018-0579-5.

29.

Key to Delivery: The (Epi-)genome Editing Vector Toolbox.

Just S, Büning H.

Methods Mol Biol. 2018;1767:147-166. doi: 10.1007/978-1-4939-7774-1_7. Review.

PMID:
29524133
30.

Transmission of rheumatoid arthritis through blood transfusion: a retrospective cohort study.

Just SA, Rostgaard K, Titlestad K, Edgren G, Erikstrup C, Ullum H, Pedersen OB, Nielsen KR, Askling J, Lindegaard H, Hjalgrim H.

Ann Rheum Dis. 2018 Oct;77(10):1536-1537. doi: 10.1136/annrheumdis-2017-212844. Epub 2018 Mar 1. No abstract available.

PMID:
29496719
31.

Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.

Just S, Chenard BL, Ceci A, Strassmaier T, Chong JA, Blair NT, Gallaschun RJ, Del Camino D, Cantin S, D'Amours M, Eickmeier C, Fanger CM, Hecker C, Hessler DP, Hengerer B, Kroker KS, Malekiani S, Mihalek R, McLaughlin J, Rast G, Witek J, Sauer A, Pryce CR, Moran MM.

PLoS One. 2018 Jan 31;13(1):e0191225. doi: 10.1371/journal.pone.0191225. eCollection 2018.

32.

Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response.

Paone C, Rudeck S, Etard C, Strähle U, Rottbauer W, Just S.

Biochem Biophys Res Commun. 2018 Feb 5;496(2):339-345. doi: 10.1016/j.bbrc.2018.01.060. Epub 2018 Jan 10.

33.

CHCHD10 mutations p.R15L and p.G66V cause motoneuron disease by haploinsufficiency.

Brockmann SJ, Freischmidt A, Oeckl P, Müller K, Ponna SK, Helferich AM, Paone C, Reinders J, Kojer K, Orth M, Jokela M, Auranen M, Udd B, Hermann A, Danzer KM, Lichtner P, Walther P, Ludolph AC, Andersen PM, Otto M, Kursula P, Just S, Weishaupt JH.

Hum Mol Genet. 2018 Feb 15;27(4):706-715. doi: 10.1093/hmg/ddx436.

PMID:
29315381
34.

Corrigendum: Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Goff BL, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Tas SW, Thurlings R, Fonseca JE, Veale DJ.

Nat Rev Rheumatol. 2017 Dec 19;14(1):60. doi: 10.1038/nrrheum.2017.206.

PMID:
29255214
35.

Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ.

Nat Rev Rheumatol. 2017 Sep 22;13(10):630. doi: 10.1038/nrrheum.2017.161.

PMID:
28935945
36.

Fibrocyte measurement in peripheral blood correlates with number of cultured mature fibrocytes in vitro and is a potential biomarker for interstitial lung disease in Rheumatoid Arthritis.

Just SA, Lindegaard H, Hejbøl EK, Davidsen JR, Bjerring N, Hansen SWK, Schrøder HD, Hansen IMJ, Barington T, Nielsen C.

Respir Res. 2017 Jul 18;18(1):141. doi: 10.1186/s12931-017-0623-9.

37.

Synovial tissue research: a state-of-the-art review.

Orr C, Vieira-Sousa E, Boyle DL, Buch MH, Buckley CD, Cañete JD, Catrina AI, Choy EHS, Emery P, Fearon U, Filer A, Gerlag D, Humby F, Isaacs JD, Just SA, Lauwerys BR, Le Goff B, Manzo A, McGarry T, McInnes IB, Najm A, Pitzalis C, Pratt A, Smith M, Tak PP, Thurlings R, Fonseca JE, Veale DJ, Tas SW.

Nat Rev Rheumatol. 2017 Aug;13(8):463-475. doi: 10.1038/nrrheum.2017.115. Epub 2017 Jul 13. Review. Erratum in: Nat Rev Rheumatol. 2017 Sep 22;13(10 ):630. Nat Rev Rheumatol. 2017 Dec 19;14 (1):60.

PMID:
28701760
38.

Authors' reply.

Andreasen RA, Andersen NS, Just SA, Christensen R, Hansen I.

Scand J Rheumatol. 2017 Jul;46(4):332-333. doi: 10.1080/03009742.2017.1309455. Epub 2017 May 31. No abstract available.

PMID:
28562143
39.

Comparison of video analysis and simulations of a drum coating process.

Boehling P, Toschkoff G, Dreu R, Just S, Kleinebudde P, Funke A, Rehbaum H, Khinast JG.

Eur J Pharm Sci. 2017 Jun 15;104:72-81. doi: 10.1016/j.ejps.2017.03.031. Epub 2017 Mar 30.

PMID:
28365300
40.

Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia.

Decher N, Ortiz-Bonnin B, Friedrich C, Schewe M, Kiper AK, Rinné S, Seemann G, Peyronnet R, Zumhagen S, Bustos D, Kockskämper J, Kohl P, Just S, González W, Baukrowitz T, Stallmeyer B, Schulze-Bahr E.

EMBO Mol Med. 2017 Apr;9(4):403-414. doi: 10.15252/emmm.201606690.

41.

Amplified pathogenic actions of angiotensin II in cysteine-rich LIM-only protein 4-negative mouse hearts.

Straubinger J, Boldt K, Kuret A, Deng L, Krattenmacher D, Bork N, Desch M, Feil R, Feil S, Nemer M, Ueffing M, Ruth P, Just S, Lukowski R.

FASEB J. 2017 Apr;31(4):1620-1638. doi: 10.1096/fj.201601186. Epub 2017 Jan 30.

PMID:
28138039
42.

Gain of function in Jak2V617F-positive T-cells.

Nishanth G, Wolleschak D, Fahldieck C, Fischer T, Mullally A, Perner F, Schnöder TM, Just S, Heidel FH, Schlüter D.

Leukemia. 2017 Apr;31(4):1000-1003. doi: 10.1038/leu.2017.6. Epub 2017 Jan 11. No abstract available.

PMID:
28074070
43.

A20 Curtails Primary but Augments Secondary CD8+ T Cell Responses in Intracellular Bacterial Infection.

Just S, Nishanth G, Buchbinder JH, Wang X, Naumann M, Lavrik I, Schlüter D.

Sci Rep. 2016 Dec 22;6:39796. doi: 10.1038/srep39796.

45.

Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish.

Just S, Raphel L, Berger IM, Bühler A, Keßler M, Rottbauer W.

PLoS One. 2016 Dec 1;11(12):e0167306. doi: 10.1371/journal.pone.0167306. eCollection 2016.

46.

Rapid analysis of bile acids in different biological matrices using LC-ESI-MS/MS for the investigation of bile acid transformation by mammalian gut bacteria.

Wegner K, Just S, Gau L, Mueller H, Gérard P, Lepage P, Clavel T, Rohn S.

Anal Bioanal Chem. 2017 Feb;409(5):1231-1245. doi: 10.1007/s00216-016-0048-1. Epub 2016 Nov 7.

PMID:
27822648
47.

Corrigendum: The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.

Lagkouvardos I, Pukall R, Abt B, Foesel BU, Meier-Kolthoff JP, Kumar N, Bresciani A, Martínez I, Just S, Ziegler C, Brugiroux S, Garzetti D, Wenning M, Bui TP, Wang J, Hugenholtz F, Plugge CM, Peterson DA, Hornef MW, Baines JF, Smidt H, Walter J, Kristiansen K, Nielsen HB, Haller D, Overmann J, Stecher B, Clavel T.

Nat Microbiol. 2016 Oct 17;1(11):16219. doi: 10.1038/nmicrobiol.2016.219. No abstract available.

PMID:
27748770
48.

Mining gut microbiome oligopeptides by functional metaproteome display.

Zantow J, Just S, Lagkouvardos I, Kisling S, Dübel S, Lepage P, Clavel T, Hust M.

Sci Rep. 2016 Oct 5;6:34337. doi: 10.1038/srep34337.

49.

The Mouse Intestinal Bacterial Collection (miBC) provides host-specific insight into cultured diversity and functional potential of the gut microbiota.

Lagkouvardos I, Pukall R, Abt B, Foesel BU, Meier-Kolthoff JP, Kumar N, Bresciani A, Martínez I, Just S, Ziegler C, Brugiroux S, Garzetti D, Wenning M, Bui TP, Wang J, Hugenholtz F, Plugge CM, Peterson DA, Hornef MW, Baines JF, Smidt H, Walter J, Kristiansen K, Nielsen HB, Haller D, Overmann J, Stecher B, Clavel T.

Nat Microbiol. 2016 Aug 8;1(10):16131. doi: 10.1038/nmicrobiol.2016.131. Erratum in: Nat Microbiol. 2016 Oct 17;1(11):16219.

PMID:
27670113
50.

Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice.

Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schlüter D, Reinhold D, Jordan BA, Gintschel P, Schraven B, Kreutz MR.

PLoS One. 2016 Sep 22;11(9):e0162863. doi: 10.1371/journal.pone.0162863. eCollection 2016.

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