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Items: 1 to 50 of 54

1.

GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis.

Littlewood-Evans A, Sarret S, Apfel V, Loesle P, Dawson J, Zhang J, Muller A, Tigani B, Kneuer R, Patel S, Valeaux S, Gommermann N, Rubic-Schneider T, Junt T, Carballido JM.

J Exp Med. 2016 Aug 22;213(9):1655-62. doi: 10.1084/jem.20160061. Epub 2016 Aug 1.

2.

The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice.

Mertz KD, Mager LF, Wasmer MH, Thiesler T, Koelzer VH, Ruzzante G, Joller S, Murdoch JR, Brümmendorf T, Genitsch V, Lugli A, Cathomas G, Moch H, Weber A, Zlobec I, Junt T, Krebs P.

Oncoimmunology. 2015 Jun 26;5(1):e1062966. eCollection 2016.

3.

Interleukin-33 Expression Indicates a Favorable Prognosis in Malignant Salivary Gland Tumors.

Rössle M, Cathomas G, Bonapace L, Sachs M, Dehler S, Storz M, Huber G, Moch H, Junt T, Mertz KD.

Int J Surg Pathol. 2016 Aug;24(5):394-400. doi: 10.1177/1066896916633856. Epub 2016 Feb 23.

PMID:
26912475
4.

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.

Zaiss MM, Rapin A, Lebon L, Dubey LK, Mosconi I, Sarter K, Piersigilli A, Menin L, Walker AW, Rougemont J, Paerewijck O, Geldhof P, McCoy KD, Macpherson AJ, Croese J, Giacomin PR, Loukas A, Junt T, Marsland BJ, Harris NL.

Immunity. 2015 Nov 17;43(5):998-1010. doi: 10.1016/j.immuni.2015.09.012. Epub 2015 Oct 27.

5.

Translating nucleic acid-sensing pathways into therapies.

Junt T, Barchet W.

Nat Rev Immunol. 2015 Sep 15;15(9):529-44. doi: 10.1038/nri3875. Epub 2015 Aug 21. Review.

PMID:
26292638
6.

The IL-33/ST2 axis augments effector T-cell responses during acute GVHD.

Reichenbach DK, Schwarze V, Matta BM, Tkachev V, Lieberknecht E, Liu Q, Koehn BH, Pfeifer D, Taylor PA, Prinz G, Dierbach H, Stickel N, Beck Y, Warncke M, Junt T, Schmitt-Graeff A, Nakae S, Follo M, Wertheimer T, Schwab L, Devlin J, Watkins SC, Duyster J, Ferrara JL, Turnquist HR, Zeiser R, Blazar BR.

Blood. 2015 May 14;125(20):3183-92. doi: 10.1182/blood-2014-10-606830. Epub 2015 Mar 26. Erratum in: Blood. 2016 Sep 1;128(9):1311.

7.

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.

Bonapace L, Coissieux MM, Wyckoff J, Mertz KD, Varga Z, Junt T, Bentires-Alj M.

Nature. 2014 Nov 6;515(7525):130-3. doi: 10.1038/nature13862. Epub 2014 Oct 22.

PMID:
25337873
8.

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis.

Trompette A, Gollwitzer ES, Yadava K, Sichelstiel AK, Sprenger N, Ngom-Bru C, Blanchard C, Junt T, Nicod LP, Harris NL, Marsland BJ.

Nat Med. 2014 Feb;20(2):159-66. doi: 10.1038/nm.3444. Epub 2014 Jan 5.

PMID:
24390308
9.

Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions.

Coelho FM, Natale D, Soriano SF, Hons M, Swoger J, Mayer J, Danuser R, Scandella E, Pieczyk M, Zerwes HG, Junt T, Sailer AW, Ludewig B, Sharpe J, Figge MT, Stein JV.

Blood. 2013 May 16;121(20):4101-9. doi: 10.1182/blood-2012-10-465336. Epub 2013 Apr 4.

PMID:
23558016
10.

Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice.

Sedhom MA, Pichery M, Murdoch JR, Foligné B, Ortega N, Normand S, Mertz K, Sanmugalingam D, Brault L, Grandjean T, Lefrancais E, Fallon PG, Quesniaux V, Peyrin-Biroulet L, Cathomas G, Junt T, Chamaillard M, Girard JP, Ryffel B.

Gut. 2013 Dec;62(12):1714-23. doi: 10.1136/gutjnl-2011-301785. Epub 2012 Nov 21.

11.

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis.

Zhang L, Orban M, Lorenz M, Barocke V, Braun D, Urtz N, Schulz C, von Brühl ML, Tirniceriu A, Gaertner F, Proia RL, Graf T, Bolz SS, Montanez E, Prinz M, Müller A, von Baumgarten L, Billich A, Sixt M, Fässler R, von Andrian UH, Junt T, Massberg S.

J Exp Med. 2012 Nov 19;209(12):2165-81. doi: 10.1084/jem.20121090. Epub 2012 Nov 12.

12.

Editorial: peer across the barrier--new live transmissions from the intestinal mucosa.

Murdoch JR, Junt T.

J Leukoc Biol. 2012 Sep;92(3):407-9. doi: 10.1189/jlb.0312159. No abstract available.

PMID:
22936835
13.

If you don't look, you won't see: intravital multiphoton imaging of primary and metastatic breast cancer.

Bonapace L, Wyckoff J, Oertner T, Van Rheenen J, Junt T, Bentires-Alj M.

J Mammary Gland Biol Neoplasia. 2012 Jun;17(2):125-9. doi: 10.1007/s10911-012-9250-8. Epub 2012 May 12. Review.

PMID:
22581273
14.

CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.

Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Förster I, Zenke M, Hieronymus T, Junt T, Zernecke A.

J Clin Invest. 2011 Jul;121(7):2898-910. doi: 10.1172/JCI44925.

15.

Th17 cells, not IL-17+ γδ T cells, drive arthritic bone destruction in mice and humans.

Pöllinger B, Junt T, Metzler B, Walker UA, Tyndall A, Allard C, Bay S, Keller R, Raulf F, Di Padova F, O'Reilly T, Horwood NJ, Patel DD, Littlewood-Evans A.

J Immunol. 2011 Feb 15;186(4):2602-12. doi: 10.4049/jimmunol.1003370. Epub 2011 Jan 7.

16.

Merkel cell polyomavirus is present in common warts and carcinoma in situ of the skin.

Mertz KD, Pfaltz M, Junt T, Schmid M, Fernandez Figueras MT, Pfaltz K, Barghorn A, Kempf W.

Hum Pathol. 2010 Oct;41(10):1369-79. doi: 10.1016/j.humpath.2010.01.023. Epub 2010 Jul 22.

PMID:
20655089
17.

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus.

Iannacone M, Moseman EA, Tonti E, Bosurgi L, Junt T, Henrickson SE, Whelan SP, Guidotti LG, von Andrian UH.

Nature. 2010 Jun 24;465(7301):1079-83. doi: 10.1038/nature09118.

18.

Inflammatory monocytes are a reservoir for Merkel cell polyomavirus.

Mertz KD, Junt T, Schmid M, Pfaltz M, Kempf W.

J Invest Dermatol. 2010 Apr;130(4):1146-51. doi: 10.1038/jid.2009.392. Epub 2009 Dec 17.

19.

Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence.

Junt T, Scandella E, Ludewig B.

Nat Rev Immunol. 2008 Oct;8(10):764-75. doi: 10.1038/nri2414. Review.

PMID:
18825130
20.

Triggering the succinate receptor GPR91 on dendritic cells enhances immunity.

Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N, Schwärzler C, Junt T, Voshol H, Meingassner JG, Mao X, Werner G, Rot A, Carballido JM.

Nat Immunol. 2008 Nov;9(11):1261-9. doi: 10.1038/ni.1657. Epub 2008 Sep 28.

PMID:
18820681
21.

Overexpression of lymphotoxin in T cells induces fulminant thymic involution.

Heikenwalder M, Prinz M, Zeller N, Lang KS, Junt T, Rossi S, Tumanov A, Schmidt H, Priller J, Flatz L, Rülicke T, Macpherson AJ, Holländer GA, Nedospasov SA, Aguzzi A.

Am J Pathol. 2008 Jun;172(6):1555-70. doi: 10.2353/ajpath.2008.070572. Epub 2008 May 15.

22.

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.

Scandella E, Bolinger B, Lattmann E, Miller S, Favre S, Littman DR, Finke D, Luther SA, Junt T, Ludewig B.

Nat Immunol. 2008 Jun;9(6):667-75. doi: 10.1038/ni.1605. Epub 2008 Apr 20.

PMID:
18425132
23.

In vivo imaging of T cell priming.

Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, Peixoto A, Flynn M, Senman B, Junt T, Wong HC, Chakraborty AK, von Andrian UH.

Sci Signal. 2008 Mar 25;1(12):pt2. doi: 10.1126/stke.112pt2.

PMID:
18364513
24.

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation.

Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, Peixoto A, Flynn MP, Senman B, Junt T, Wong HC, Chakraborty AK, von Andrian UH.

Nat Immunol. 2008 Mar;9(3):282-91. doi: 10.1038/ni1559. Epub 2008 Jan 20.

25.

Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues.

Massberg S, Schaerli P, Knezevic-Maramica I, Köllnberger M, Tubo N, Moseman EA, Huff IV, Junt T, Wagers AJ, Mazo IB, von Andrian UH.

Cell. 2007 Nov 30;131(5):994-1008.

26.

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells.

Junt T, Moseman EA, Iannacone M, Massberg S, Lang PA, Boes M, Fink K, Henrickson SE, Shayakhmetov DM, Di Paolo NC, van Rooijen N, Mempel TR, Whelan SP, von Andrian UH.

Nature. 2007 Nov 1;450(7166):110-4. Epub 2007 Oct 14.

PMID:
17934446
27.

Dynamic visualization of thrombopoiesis within bone marrow.

Junt T, Schulze H, Chen Z, Massberg S, Goerge T, Krueger A, Wagner DD, Graf T, Italiano JE Jr, Shivdasani RA, von Andrian UH.

Science. 2007 Sep 21;317(5845):1767-70.

28.

Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns.

Hauser AE, Junt T, Mempel TR, Sneddon MW, Kleinstein SH, Henrickson SE, von Andrian UH, Shlomchik MJ, Haberman AM.

Immunity. 2007 May;26(5):655-67.

29.

Dendritic cell-independent B cell activation during acute virus infection: a role for early CCR7-driven B-T helper cell collaboration.

Scandella E, Fink K, Junt T, Senn BM, Lattmann E, Förster R, Hengartner H, Ludewig B.

J Immunol. 2007 Feb 1;178(3):1468-76.

30.

Rulers over randomness: stroma cells guide lymphocyte migration in lymph nodes.

Mempel TR, Junt T, von Andrian UH.

Immunity. 2006 Dec;25(6):867-9. Review.

31.

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells.

Mora JR, Iwata M, Eksteen B, Song SY, Junt T, Senman B, Otipoby KL, Yokota A, Takeuchi H, Ricciardi-Castagnoli P, Rajewsky K, Adams DH, von Andrian UH.

Science. 2006 Nov 17;314(5802):1157-60.

32.

Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling.

Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM.

J Clin Invest. 2006 Sep;116(9):2456-63.

33.

Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia.

Kamphuis E, Junt T, Waibler Z, Forster R, Kalinke U.

Blood. 2006 Nov 15;108(10):3253-61. Epub 2006 Jul 25.

PMID:
16868248
34.

Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs.

Pearce G, Angeli V, Randolph GJ, Junt T, von Andrian U, Schnittler HJ, Jessberger R.

Nat Immunol. 2006 Aug;7(8):827-34. Epub 2006 Jul 16.

PMID:
16845395
35.

Expression of lymphotoxin beta governs immunity at two distinct levels.

Junt T, Tumanov AV, Harris N, Heikenwalder M, Zeller N, Kuprash DV, Aguzzi A, Ludewig B, Nedospasov SA, Zinkernagel RM.

Eur J Immunol. 2006 Aug;36(8):2061-75.

36.

Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses.

Fink K, Lang KS, Manjarrez-Orduno N, Junt T, Senn BM, Holdener M, Akira S, Zinkernagel RM, Hengartner H.

Eur J Immunol. 2006 Aug;36(8):2094-105.

37.

CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses.

Junt T, Fink K, Förster R, Senn B, Lipp M, Muramatsu M, Zinkernagel RM, Ludewig B, Hengartner H.

J Immunol. 2005 Dec 1;175(11):7109-16.

38.

Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation.

Lang KS, Recher M, Navarini AA, Harris NL, Löhning M, Junt T, Probst HC, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2005 Mar;35(3):738-45.

39.

Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.

Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM.

Nat Med. 2005 Feb;11(2):138-45. Epub 2005 Jan 16. Erratum in: Nat Med. 2005 Nov;11(11):1256.

PMID:
15654326
40.

Impact of CCR7 on priming and distribution of antiviral effector and memory CTL.

Junt T, Scandella E, Förster R, Krebs P, Krautwald S, Lipp M, Hengartner H, Ludewig B.

J Immunol. 2004 Dec 1;173(11):6684-93.

41.

Determining control parameters for dendritic cell-cytotoxic T lymphocyte interaction.

Ludewig B, Krebs P, Junt T, Metters H, Ford NJ, Anderson RM, Bocharov G.

Eur J Immunol. 2004 Sep;34(9):2407-18.

42.

Underwhelming the immune response: effect of slow virus growth on CD8+-T-lymphocyte responses.

Bocharov G, Ludewig B, Bertoletti A, Klenerman P, Junt T, Krebs P, Luzyanina T, Fraser C, Anderson RM.

J Virol. 2004 Mar;78(5):2247-54. Erratum in: J Virol. 2004 Jun;78(11):6079.

43.

Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration.

Heikenwalder M, Polymenidou M, Junt T, Sigurdson C, Wagner H, Akira S, Zinkernagel R, Aguzzi A.

Nat Med. 2004 Feb;10(2):187-92. Epub 2004 Jan 25.

PMID:
14745443
44.

Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion.

Prinz M, Heikenwalder M, Junt T, Schwarz P, Glatzel M, Heppner FL, Fu YX, Lipp M, Aguzzi A.

Nature. 2003 Oct 30;425(6961):957-62. Epub 2003 Oct 15.

PMID:
14562059
45.

Dendritic cell homeostasis in the regulation of self-reactivity.

Ludewig B, Krebs P, Junt T, Bocharov G.

Curr Pharm Des. 2003;9(3):221-31. Review.

PMID:
12570827
46.

Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis.

Frigerio S, Junt T, Lu B, Gerard C, Zumsteg U, Holländer GA, Piali L.

Nat Med. 2002 Dec;8(12):1414-20. Epub 2002 Nov 4.

PMID:
12415259
47.

Antiviral immune responses in the absence of organized lymphoid T cell zones in plt/plt mice.

Junt T, Nakano H, Dumrese T, Kakiuchi T, Odermatt B, Zinkernagel RM, Hengartner H, Ludewig B.

J Immunol. 2002 Jun 15;168(12):6032-40.

48.

CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: modulation by FTY720.

Henning G, Ohl L, Junt T, Reiterer P, Brinkmann V, Nakano H, Hohenberger W, Lipp M, Förster R.

J Exp Med. 2001 Dec 17;194(12):1875-81.

49.

Dendritic cells in autoimmune diseases.

Ludewig B, Junt T, Hengartner H, Zinkernagel RM.

Curr Opin Immunol. 2001 Dec;13(6):657-62. Review.

PMID:
11677086
50.

CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability.

Maloy KJ, Burkhart C, Junt TM, Odermatt B, Oxenius A, Piali L, Zinkernagel RM, Hengartner H.

J Exp Med. 2000 Jun 19;191(12):2159-70.

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