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Items: 36

1.

Regulation of the Germinal Center Reaction and Somatic Hypermutation Dynamics by Homologous Recombination.

Hirth G, Svensson CM, Böttcher K, Ullrich S, Figge MT, Jungnickel B.

J Immunol. 2019 Aug 9. pii: ji1900483. doi: 10.4049/jimmunol.1900483. [Epub ahead of print]

PMID:
31399517
2.

Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies.

Irmscher S, Brix SR, Zipfel SLH, Halder LD, Mutlutürk S, Wulf S, Girdauskas E, Reichenspurner H, Stahl RAK, Jungnickel B, Wiech T, Zipfel PF, Skerka C.

Nat Commun. 2019 Jul 4;10(1):2961. doi: 10.1038/s41467-019-10766-0.

3.

The nuclear pore proteins Nup88/214 and T-cell acute lymphatic leukemia-associated NUP214 fusion proteins regulate Notch signaling.

Kindermann B, Valkova C, Krämer A, Perner B, Engelmann C, Behrendt L, Kritsch D, Jungnickel B, Kehlenbach RH, Oswald F, Englert C, Kaether C.

J Biol Chem. 2019 Aug 2;294(31):11741-11750. doi: 10.1074/jbc.RA118.006357. Epub 2019 Jun 11.

PMID:
31186352
4.

Restriction of AID activity and somatic hypermutation by PARP-1.

Tepper S, Mortusewicz O, Członka E, Bello A, Schmidt A, Jeschke J, Fischbach A, Pfeil I, Petersen-Mahrt SK, Mangerich A, Helleday T, Leonhardt H, Jungnickel B.

Nucleic Acids Res. 2019 May 25. pii: gkz466. doi: 10.1093/nar/gkz466. [Epub ahead of print]

PMID:
31127309
5.

PARP activation promotes nuclear AID accumulation in lymphoma cells.

Tepper S, Jeschke J, Böttcher K, Schmidt A, Davari K, Müller P, Kremmer E, Hemmerich P, Pfeil I, Jungnickel B.

Oncotarget. 2016 Mar 15;7(11):13197-208. doi: 10.18632/oncotarget.7603.

6.

Checkpoint kinase 2 is required for efficient immunoglobulin diversification.

Davari K, Frankenberger S, Schmidt A, Tomi NS, Jungnickel B.

Cell Cycle. 2014;13(23):3659-69. doi: 10.4161/15384101.2014.964112.

7.

Analysis of SHPRH functions in DNA repair and immunoglobulin diversification.

Tomi NS, Davari K, Grotzky D, Loos F, Böttcher K, Frankenberger S, Jungnickel B.

DNA Repair (Amst). 2014 Dec;24:63-72. doi: 10.1016/j.dnarep.2014.09.010. Epub 2014 Oct 11.

PMID:
25311267
8.

Checkpoint kinase 1 negatively regulates somatic hypermutation.

Frankenberger S, Davari K, Fischer-Burkart S, Böttcher K, Tomi NS, Zimber-Strobl U, Jungnickel B.

Nucleic Acids Res. 2014 Apr;42(6):3666-74. doi: 10.1093/nar/gkt1378. Epub 2014 Jan 13.

9.

Ubc13 dosage is critical for immunoglobulin gene conversion and gene targeting in vertebrate cells.

Ertongur I, Tomi NS, Kutzera A, Fischer-Burkart S, Jungnickel B.

Nucleic Acids Res. 2010 Aug;38(14):4701-7. doi: 10.1093/nar/gkq154. Epub 2010 Mar 11.

10.

c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma.

Scheller H, Tobollik S, Kutzera A, Eder M, Unterlehberg J, Pfeil I, Jungnickel B.

Oncogene. 2010 Feb 11;29(6):888-97. doi: 10.1038/onc.2009.377. Epub 2009 Nov 2.

PMID:
19881537
11.

The expression of activation induced cytidine deaminase in follicular lymphoma is independent of prognosis and stage.

Willenbrock K, Renné C, Rottenkolber M, Klapper W, Dreyling M, Engelhard M, Küppers R, Hansmann ML, Jungnickel B.

Histopathology. 2009 Mar;54(4):509-12. doi: 10.1111/j.1365-2559.2009.03241.x. No abstract available.

PMID:
19309412
12.

Expression of activation-induced cytidine deaminase in malignant lymphomas infiltrating the bone marrow.

Engels K, Jungnickel B, Tobollik S, Hansmann ML, Kriener S, Willenbrock K.

Appl Immunohistochem Mol Morphol. 2008 Dec;16(6):521-9. doi: 10.1097/PAI.0b013e3181758ce5.

PMID:
18776814
13.

Non-conservative homologous recombination in human B lymphocytes is promoted by activation-induced cytidine deaminase and transcription.

Mierau M, Drexler GA, Kutzera A, Braunschmidt K, Ellwart J, Eckardt-Schupp F, Fritz E, Bachl J, Jungnickel B.

Nucleic Acids Res. 2008 Oct;36(17):5591-601. doi: 10.1093/nar/gkn542. Epub 2008 Aug 30.

14.

False moves for survival: error-prone DNA repair in adaptive immunity.

Jungnickel B.

Cell Cycle. 2006 Dec;5(24):2856-61. Epub 2006 Dec 15.

PMID:
17172871
15.

Epstein-Barr virus nuclear antigen 2 inhibits AID expression during EBV-driven B-cell growth.

Tobollik S, Meyer L, Buettner M, Klemmer S, Kempkes B, Kremmer E, Niedobitek G, Jungnickel B.

Blood. 2006 Dec 1;108(12):3859-64. Epub 2006 Aug 1.

16.

Involvement of Rad18 in somatic hypermutation.

Bachl J, Ertongur I, Jungnickel B.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12081-6. Epub 2006 Jul 27.

17.

Human splenic marginal zone B cells lack expression of activation-induced cytidine deaminase.

Willenbrock K, Jungnickel B, Hansmann ML, Küppers R.

Eur J Immunol. 2005 Oct;35(10):3002-7.

18.

Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus.

Mancao C, Altmann M, Jungnickel B, Hammerschmidt W.

Blood. 2005 Dec 15;106(13):4339-44. Epub 2005 Aug 2.

19.

Absence of immunoglobulin class switch in primary lymphomas of the central nervous system.

Montesinos-Rongen M, Schmitz R, Courts C, Stenzel W, Bechtel D, Niedobitek G, Blümcke I, Reifenberger G, von Deimling A, Jungnickel B, Wiestler OD, Küppers R, Deckert M.

Am J Pathol. 2005 Jun;166(6):1773-9.

20.

Differential expression of activation-induced cytidine deaminase (AID) in nodular lymphocyte-predominant and classical Hodgkin lymphoma.

Greiner A, Tobollik S, Buettner M, Jungnickel B, Herrmann K, Kremmer E, Niedobitek G.

J Pathol. 2005 Apr;205(5):541-7.

PMID:
15732141
21.

Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma.

Schwering I, Bräuninger A, Klein U, Jungnickel B, Tinguely M, Diehl V, Hansmann ML, Dalla-Favera R, Rajewsky K, Küppers R.

Blood. 2003 Feb 15;101(4):1505-12. Epub 2002 Sep 26.

22.

Somatic mutation of the CD95 gene in human B cells as a side-effect of the germinal center reaction.

Müschen M, Re D, Jungnickel B, Diehl V, Rajewsky K, Küppers R.

J Exp Med. 2000 Dec 18;192(12):1833-40.

23.

Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma.

Jungnickel B, Staratschek-Jox A, Bräuninger A, Spieker T, Wolf J, Diehl V, Hansmann ML, Rajewsky K, Küppers R.

J Exp Med. 2000 Jan 17;191(2):395-402.

24.
25.
26.

Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation.

Hanein D, Matlack KE, Jungnickel B, Plath K, Kalies KU, Miller KR, Rapoport TA, Akey CW.

Cell. 1996 Nov 15;87(4):721-32.

27.

Approaching the mechanism of protein transport across the ER membrane.

Rapoport TA, Rolls MM, Jungnickel B.

Curr Opin Cell Biol. 1996 Aug;8(4):499-504. Review.

PMID:
8791447
28.
29.

Regulation by the ribosome of the GTPase of the signal-recognition particle during protein targeting.

Bacher G, Lütcke H, Jungnickel B, Rapoport TA, Dobberstein B.

Nature. 1996 May 16;381(6579):248-51.

PMID:
8622769
30.

Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes.

Rapoport TA, Jungnickel B, Kutay U.

Annu Rev Biochem. 1996;65:271-303. Review.

PMID:
8811181
31.

A hydrophobic region of ricin A chain which may have a role in membrane translocation can function as an efficient noncleaved signal peptide.

Chaddock JA, Roberts LM, Jungnickel B, Lord JM.

Biochem Biophys Res Commun. 1995 Dec 5;217(1):68-73.

PMID:
8526941
32.

Signal sequence processing in rough microsomes.

Lyko F, Martoglio B, Jungnickel B, Rapoport TA, Dobberstein B.

J Biol Chem. 1995 Aug 25;270(34):19873-8.

33.
34.

The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum.

Oliver J, Jungnickel B, Görlich D, Rapoport T, High S.

FEBS Lett. 1995 Apr 3;362(2):126-30.

35.

Protein translocation: common themes from bacteria to man.

Jungnickel B, Rapoport TA, Hartmann E.

FEBS Lett. 1994 Jun 6;346(1):73-7. Review.

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