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PTPσ inhibitors promote hematopoietic stem cell regeneration.

Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP.

Nat Commun. 2019 Aug 14;10(1):3667. doi: 10.1038/s41467-019-11490-5.


A Novel Therapeutic Induces DEPTOR Degradation in Multiple Myeloma Cells with Resulting Tumor Cytotoxicity.

Vega MI, Shi Y, Frost P, Huerta-Yepez S, Antonio-Andres G, Hernandez-Pando R, Lee J, Jung ME, Gera JF, Lichtenstein A.

Mol Cancer Ther. 2019 Oct;18(10):1822-1831. doi: 10.1158/1535-7163.MCT-19-0115. Epub 2019 Aug 8.


Antiestrogens in combination with immune checkpoint inhibitors in breast cancer immunotherapy.

Márquez-Garbán DC, Deng G, Comin-Anduix B, Garcia AJ, Xing Y, Chen HW, Cheung-Lau G, Hamilton N, Jung ME, Pietras RJ.

J Steroid Biochem Mol Biol. 2019 Oct;193:105415. doi: 10.1016/j.jsbmb.2019.105415. Epub 2019 Jun 19.


Synthesis of β-Amino Diaryldienones Using the Mannich Reaction.

Elshan NGRD, Rettig MB, Jung ME.

Org Lett. 2019 Jun 7;21(11):4039-4043. doi: 10.1021/acs.orglett.9b01195. Epub 2019 May 13.


Sprint exercise snacks: a novel approach to increase aerobic fitness.

Little JP, Langley J, Lee M, Myette-Côté E, Jackson G, Durrer C, Gibala MJ, Jung ME.

Eur J Appl Physiol. 2019 May;119(5):1203-1212. doi: 10.1007/s00421-019-04110-z. Epub 2019 Mar 7.


Short-term exercise training reduces glycaemic variability and lowers circulating endothelial microparticles in overweight and obese women at elevated risk of type 2 diabetes.

Rafiei H, Robinson E, Barry J, Jung ME, Little JP.

Eur J Sport Sci. 2019 Sep;19(8):1140-1149. doi: 10.1080/17461391.2019.1576772. Epub 2019 Feb 18.


The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation.

Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D.

Radiat Res. 2019 Apr;191(4):323-334. doi: 10.1667/RR15231.1. Epub 2019 Feb 7.


Correction: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.

Benavides-Serrato A, Lee J, Holmes B, Landon KA, Bashir T, Jung ME, Lichtenstein A, Gera J.

PLoS One. 2019 Feb 6;14(2):e0212160. doi: 10.1371/journal.pone.0212160. eCollection 2019.


Mapping behavior change techniques to characterize a social cognitive theory informed physical activity intervention for adults at risk of type 2 diabetes mellitus.

Bourne JE, Ivanova E, Gainforth HL, Jung ME.

Transl Behav Med. 2019 Feb 4. doi: 10.1093/tbm/ibz008. [Epub ahead of print]


Molecules targeting the androgen receptor (AR) signaling axis beyond the AR-Ligand binding domain.

Elshan NGRD, Rettig MB, Jung ME.

Med Res Rev. 2019 May;39(3):910-960. doi: 10.1002/med.21548. Epub 2018 Nov 22. Review.


A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.

Campagna J, Spilman P, Jagodzinska B, Bai D, Hatami A, Zhu C, Bilousova T, Jun M, Elias CJ, Pham J, Cole G, LaDu MJ, Jung ME, Bredesen DE, John V.

Sci Rep. 2018 Dec 4;8(1):17574. doi: 10.1038/s41598-018-35687-8.


Broad-spectrum antiviral JL122 blocks infection and inhibits transmission of aquatic rhabdoviruses.

Balmer BF, Getchell RG, Powers RL, Lee J, Zhang T, Jung ME, Purcell MK, Snekvik K, Aguilar HC.

Virology. 2018 Dec;525:143-149. doi: 10.1016/j.virol.2018.09.009. Epub 2018 Oct 1.


'I'm on the train and I can't stop it': Western Canadians' reactions to prediabetes and the role of self-compassion.

Strachan SM, Bean C, Jung ME.

Health Soc Care Community. 2018 Nov;26(6):979-987. doi: 10.1111/hsc.12628. Epub 2018 Aug 3.


Chronic benzodiazepine suppresses translocator protein and elevates amyloid β in mice.

Tan S, Metzger DB, Jung ME.

Pharmacol Biochem Behav. 2018 Sep;172:59-67. doi: 10.1016/j.pbb.2018.07.005. Epub 2018 Jul 18.


Short-term exercise training reduces anti-inflammatory action of interleukin-10 in adults with obesity.

Barry JC, Simtchouk S, Durrer C, Jung ME, Mui AL, Little JP.

Cytokine. 2018 Nov;111:460-469. doi: 10.1016/j.cyto.2018.05.035. Epub 2018 Jun 6.


A Liquid Chromatography-Quadrupole-Time-of-Flight Mass Spectrometric Assay for the Quantification of Fabry Disease Biomarker Globotriaosylceramide (GB3) in Fabry Model Mouse.

Shin SH, Park MH, Byeon JJ, Lee BI, Park Y, Ko AR, Seong MR, Lee S, Kim MR, Seo J, Jung ME, Jin DK, Shin YG.

Pharmaceutics. 2018 Jun 7;10(2). pii: E69. doi: 10.3390/pharmaceutics10020069.


Exploring the effectiveness of a school-based physical activity policy in British Columbia, Canada: a mixed-methods observational study.

Weatherson KA, Locke SR, Jung ME.

Transl Behav Med. 2019 Mar 1;9(2):246-255. doi: 10.1093/tbm/iby053.


High-Intensity Interval or Continuous Moderate Exercise: A 24-Week Pilot Trial.

Locke SR, Bourne JE, Beauchamp MR, Little JP, Barry J, Singer J, Jung ME.

Med Sci Sports Exerc. 2018 Oct;50(10):2067-2075. doi: 10.1249/MSS.0000000000001668.


The influence of high-intensity interval training and moderate-intensity continuous training on sedentary time in overweight and obese adults.

Nugent SF, Jung ME, Bourne JE, Loeppky J, Arnold A, Little JP.

Appl Physiol Nutr Metab. 2018 Jul;43(7):747-750. doi: 10.1139/apnm-2017-0453. Epub 2018 Feb 7.


Evaluation of a community-based, family focused healthy weights initiative using the RE-AIM framework.

Jung ME, Bourne JE, Gainforth HL.

Int J Behav Nutr Phys Act. 2018 Jan 26;15(1):13. doi: 10.1186/s12966-017-0638-0.


Evaluation of an mHealth App (DeStressify) on University Students' Mental Health: Pilot Trial.

Lee RA, Jung ME.

JMIR Ment Health. 2018 Jan 23;5(1):e2. doi: 10.2196/mental.8324.


Novel indazole-based small compounds enhance TRAIL-induced apoptosis by inhibiting the MKK7-TIPRL interaction in hepatocellular carcinoma.

Yoon JY, Lee JJ, Gu S, Jung ME, Cho HS, Lim JH, Jun SY, Ahn JH, Min JS, Choi MH, Jeon SJ, Lee YJ, Go A, Heo YJ, Jung CR, Choi G, Lee K, Jeon MK, Kim NS.

Oncotarget. 2017 Nov 3;8(68):112610-112622. doi: 10.18632/oncotarget.22614. eCollection 2017 Dec 22.


Synthesis and Structure-Activity Relationship (SAR) Studies of Novel Pyrazolopyridine Derivatives as Inhibitors of Enterovirus Replication.

Xing Y, Zuo J, Krogstad P, Jung ME.

J Med Chem. 2018 Feb 22;61(4):1688-1703. doi: 10.1021/acs.jmedchem.7b01863. Epub 2018 Jan 31.


Barriers and facilitators to the implementation of a school-based physical activity policy in Canada: application of the theoretical domains framework.

Weatherson KA, McKay R, Gainforth HL, Jung ME.

BMC Public Health. 2017 Oct 23;17(1):835. doi: 10.1186/s12889-017-4846-y.


Structure-activity relationship study of small molecule inhibitors of the DEPTOR-mTOR interaction.

Lee J, Shi Y, Vega M, Yang Y, Gera J, Jung ME, Lichtenstein A.

Bioorg Med Chem Lett. 2017 Oct 15;27(20):4714-4724. doi: 10.1016/j.bmcl.2017.09.002. Epub 2017 Sep 6.


Strategies for public health initiatives targeting dairy consumption in young children: a qualitative formative investigation of parent perceptions.

Jung ME, Bourne JE, Buchholz A, Martin Ginis KA.

Public Health Nutr. 2017 Nov;20(16):2893-2908. doi: 10.1017/S1368980017002038. Epub 2017 Aug 30.


Intermittent hypoxia training: Powerful, non-invasive cerebroprotection against ethanol withdrawal excitotoxicity.

Jung ME, Mallet RT.

Respir Physiol Neurobiol. 2018 Oct;256:67-78. doi: 10.1016/j.resp.2017.08.007. Epub 2017 Aug 12. Review.


4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues.

Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH.

PLoS One. 2017 Jul 21;12(7):e0181577. doi: 10.1371/journal.pone.0181577. eCollection 2017.


Fluorinated Nucleotide Modifications Modulate Allele Selectivity of SNP-Targeting Antisense Oligonucleotides.

Østergaard ME, Nichols J, Dwight TA, Lima W, Jung ME, Swayze EE, Seth PP.

Mol Ther Nucleic Acids. 2017 Jun 16;7:20-30. doi: 10.1016/j.omtn.2017.02.001. Epub 2017 Feb 9.


Intermittent hypoxia training blunts cerebrocortical presenilin 1 overexpression and amyloid-β accumulation in ethanol-withdrawn rats.

Ryou MG, Mallet RT, Metzger DB, Jung ME.

Am J Physiol Regul Integr Comp Physiol. 2017 Jul 1;313(1):R10-R18. doi: 10.1152/ajpregu.00050.2017. Epub 2017 May 10.


Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma.

Benavides-Serrato A, Lee J, Holmes B, Landon KA, Bashir T, Jung ME, Lichtenstein A, Gera J.

PLoS One. 2017 Apr 28;12(4):e0176599. doi: 10.1371/journal.pone.0176599. eCollection 2017. Erratum in: PLoS One. 2019 Feb 6;14(2):e0212160.


Differences in interregional brain connectivity in children with unilateral hearing loss.

Jung ME, Colletta M, Coalson R, Schlaggar BL, Lieu JEC.

Laryngoscope. 2017 Nov;127(11):2636-2645. doi: 10.1002/lary.26587. Epub 2017 Apr 20.


Short-Term Exercise Training Alters Leukocyte Chemokine Receptors in Obese Adults.

Barry JC, Simtchouk S, Durrer C, Jung ME, Little JP.

Med Sci Sports Exerc. 2017 Aug;49(8):1631-1640. doi: 10.1249/MSS.0000000000001261. Erratum in: Med Sci Sports Exerc. 2018 Apr;50(4):879.


Self-compassion directly and indirectly predicts dietary adherence and quality of life among adults with celiac disease.

Dowd AJ, Jung ME.

Appetite. 2017 Jun 1;113:293-300. doi: 10.1016/j.appet.2017.02.023. Epub 2017 Feb 20.


Young Adults' Perceptions of Calcium Intake and Health: A Qualitative Study.

Marcinow ML, Randall Simpson JA, Whiting SJ, Jung ME, Buchholz AC.

Health Educ Behav. 2017 Dec;44(6):898-906. doi: 10.1177/1090198116688439. Epub 2017 Feb 8.


NMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors.

Chan AH, Yi SW, Weiner EM, Amer BR, Sue CK, Wereszczynski J, Dillen CA, Senese S, Torres JZ, McCammon JA, Miller LS, Jung ME, Clubb RT.

Chem Biol Drug Des. 2017 Sep;90(3):327-344. doi: 10.1111/cbdd.12962. Epub 2017 Mar 6.


Inhibition of an Aquatic Rhabdovirus Demonstrates Promise of a Broad-Spectrum Antiviral for Use in Aquaculture.

Balmer BF, Powers RL, Zhang TH, Lee J, Vigant F, Lee B, Jung ME, Purcell MK, Snekvik K, Aguilar HC.

J Virol. 2017 Jan 31;91(4). pii: e02181-16. doi: 10.1128/JVI.02181-16. Print 2017 Feb 15.


Targeted Messages Increase Dairy Consumption in Adults: a Randomized Controlled Trial.

Jung ME, Latimer-Cheung AE, Bourne JE, Martin Ginis KA.

Ann Behav Med. 2017 Feb;51(1):57-66. doi: 10.1007/s12160-016-9828-2.


Synthesis of 2-Ethenylcyclopropyl Aryl Ketones via Intramolecular SN2-like Displacement of an Ester.

Jung ME, Sun DL, Dwight TA, Yu P, Li W, Houk KN.

Org Lett. 2016 Oct 7;18(19):5138-5141. Epub 2016 Sep 12.


Cytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.

Shi Y, Daniels-Wells TR, Frost P, Lee J, Finn RS, Bardeleben C, Penichet ML, Jung ME, Gera J, Lichtenstein A.

Cancer Res. 2016 Oct 1;76(19):5822-5831. Epub 2016 Aug 16.


A sex difference in oxidative stress and behavioral suppression induced by ethanol withdrawal in rats.

Jung ME, Metzger DB.

Behav Brain Res. 2016 Nov 1;314:199-214. doi: 10.1016/j.bbr.2016.07.054. Epub 2016 Aug 5.


Psychosocial predictors of changes in adolescent girls' physical activity and dietary behaviors over the course of the Go Girls! group-based mentoring program.

Dowd AJ, Chen MY, Schmader T, Jung ME, Zumbo BD, Beauchamp MR.

Health Educ Res. 2016 Aug;31(4):478-91. doi: 10.1093/her/cyw021. Epub 2016 Jun 19.


A Theory-Based Exercise App to Enhance Exercise Adherence: A Pilot Study.

Voth EC, Oelke ND, Jung ME.

JMIR Mhealth Uhealth. 2016 Jun 15;4(2):e62. doi: 10.2196/mhealth.4997.


The Role of Presenilin-1 in the Excitotoxicity of Ethanol Withdrawal.

Jung ME, Metzger DB, Das HK.

J Pharmacol Exp Ther. 2016 Sep;358(3):516-26. doi: 10.1124/jpet.116.233361. Epub 2016 Jun 8.


Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced Internal Ribosome Entry Site (IRES)-mediated Translation of Cyclin D1 and c-MYC mRNAs to Treat Glioblastoma.

Holmes B, Lee J, Landon KA, Benavides-Serrato A, Bashir T, Jung ME, Lichtenstein A, Gera J.

J Biol Chem. 2016 Jul 1;291(27):14146-59. doi: 10.1074/jbc.M116.726927. Epub 2016 May 11.


The "Lid" in the Streptococcus pneumoniae SrtC1 Sortase Adopts a Rigid Structure that Regulates Substrate Access to the Active Site.

Jacobitz AW, Naziga EB, Yi SW, McConnell SA, Peterson R, Jung ME, Clubb RT, Wereszczynski J.

J Phys Chem B. 2016 Aug 25;120(33):8302-12. doi: 10.1021/acs.jpcb.6b01930. Epub 2016 May 5.


Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.

Jung ME, Byun BJ, Kim HM, Lee JY, Park JH, Lee N, Son YH, Choi SU, Yang KM, Kim SJ, Lee K, Kim YC, Choi G.

Bioorg Med Chem Lett. 2016 Jun 1;26(11):2719-23. doi: 10.1016/j.bmcl.2016.03.111. Epub 2016 Apr 1.


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