Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 100

1.

Antibiotic therapy in acute pancreatitis: From global overuse to evidence based recommendations.

Párniczky A, Lantos T, Tóth EM, Szakács Z, Gódi S, Hágendorn R, Illés D, Koncz B, Márta K, Mikó A, Mosztbacher D, Németh BC, Pécsi D, Szabó A, Szücs Á, Varjú P, Szentesi A, Darvasi E, Erőss B, Izbéki F, Gajdán L, Halász A, Vincze Á, Szabó I, Pár G, Bajor J, Sarlós P, Czimmer J, Hamvas J, Takács T, Szepes Z, Czakó L, Varga M, Novák J, Bod B, Szepes A, Sümegi J, Papp M, Góg C, Török I, Huang W, Xia Q, Xue P, Li W, Chen W, Shirinskaya NV, Poluektov VL, Shirinskaya AV, Hegyi PJ, Bátovský M, Rodriguez-Oballe JA, Salas IM, Lopez-Diaz J, Dominguez-Munoz JE, Molero X, Pando E, Ruiz-Rebollo ML, Burgueño-Gómez B, Chang YT, Chang MC, Sud A, Moore D, Sutton R, Gougol A, Papachristou GI, Susak YM, Tiuliukin IO, Gomes AP, Oliveira MJ, Aparício DJ, Tantau M, Kurti F, Kovacheva-Slavova M, Stecher SS, Mayerle J, Poropat G, Das K, Marino MV, Capurso G, Małecka-Panas E, Zatorski H, Gasiorowska A, Fabisiak N, Ceranowicz P, Kuśnierz-Cabala B, Carvalho JR, Fernandes SR, Chang JH, Choi EK, Han J, Bertilsson S, Jumaa H, Sandblom G, Kacar S, Baltatzis M, Varabei AV, Yeshy V, Chooklin S, Kozachenko A, Veligotsky N, Hegyi P; Hungarian Pancreatic Study Group.

Pancreatology. 2019 Apr 19. pii: S1424-3903(19)30091-2. doi: 10.1016/j.pan.2019.04.003. [Epub ahead of print]

PMID:
31068256
2.

Pten controls B-cell responsiveness and germinal center reaction by regulating the expression of IgD BCR.

Setz CS, Khadour A, Renna V, Iype J, Gentner E, He X, Datta M, Young M, Nitschke L, Wienands J, Maity PC, Reth M, Jumaa H.

EMBO J. 2019 Jun 3;38(11). pii: e100249. doi: 10.15252/embj.2018100249. Epub 2019 Apr 23.

3.

Carbohydrate-dependent B cell activation by fucose-binding bacterial lectins.

Wilhelm I, Levit-Zerdoun E, Jakob J, Villringer S, Frensch M, Übelhart R, Landi A, Müller P, Imberty A, Thuenauer R, Claudinon J, Jumaa H, Reth M, Eibel H, Hobeika E, Römer W.

Sci Signal. 2019 Mar 5;12(571). pii: eaao7194. doi: 10.1126/scisignal.aao7194.

PMID:
30837305
4.

Differences in Self-Recognition between Secreted Antibody and Membrane-Bound B Cell Antigen Receptor.

Iype J, Datta M, Khadour A, Übelhart R, Nicolò A, Rollenske T, Dühren-von Minden M, Wardemann H, Maity PC, Jumaa H.

J Immunol. 2019 Mar 1;202(5):1417-1427. doi: 10.4049/jimmunol.1800690. Epub 2019 Jan 25.

5.

Isotype Specific Assembly of B Cell Antigen Receptors and Synergism With Chemokine Receptor CXCR4.

Maity PC, Datta M, Nicolò A, Jumaa H.

Front Immunol. 2018 Dec 18;9:2988. doi: 10.3389/fimmu.2018.02988. eCollection 2018. Review.

6.

IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia.

Alsadeq A, Lenk L, Vadakumchery A, Cousins A, Vokuhl C, Khadour A, Vogiatzi F, Seyfried F, Meyer LH, Cario G, Hobeika E, Debatin KM, Halsey C, Schrappe M, Schewe DM, Jumaa H.

Blood. 2018 Oct 11;132(15):1614-1617. doi: 10.1182/blood-2018-04-844209. Epub 2018 Aug 28. No abstract available.

7.

PI3K-Mediated Blimp-1 Activation Controls B Cell Selection and Homeostasis.

Setz CS, Hug E, Khadour A, Abdelrasoul H, Bilal M, Hobeika E, Jumaa H.

Cell Rep. 2018 Jul 10;24(2):391-405. doi: 10.1016/j.celrep.2018.06.035.

8.

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.

Imkeller K, Scally SW, Bosch A, Martí GP, Costa G, Triller G, Murugan R, Renna V, Jumaa H, Kremsner PG, Sim BKL, Hoffman SL, Mordmüller B, Levashina EA, Julien JP, Wardemann H.

Science. 2018 Jun 22;360(6395):1358-1362. doi: 10.1126/science.aar5304. Epub 2018 Jun 7.

9.

Index versus delayed cholecystectomy in mild gallstone pancreatitis: results of a randomized controlled trial.

Noel R, Arnelo U, Lundell L, Hammarqvist F, Jumaa H, Enochsson L, Sandblom G.

HPB (Oxford). 2018 Oct;20(10):932-938. doi: 10.1016/j.hpb.2018.03.016. Epub 2018 Apr 25.

PMID:
29703649
10.

B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.

Xiao G, Chan LN, Klemm L, Braas D, Chen Z, Geng H, Zhang QC, Aghajanirefah A, Cosgun KN, Sadras T, Lee J, Mirzapoiazova T, Salgia R, Ernst T, Hochhaus A, Jumaa H, Jiang X, Weinstock DM, Graeber TG, Müschen M.

Cell. 2018 Apr 5;173(2):470-484.e18. doi: 10.1016/j.cell.2018.02.048. Epub 2018 Mar 15.

11.

PI3K induces B-cell development and regulates B cell identity.

Abdelrasoul H, Werner M, Setz CS, Okkenhaug K, Jumaa H.

Sci Rep. 2018 Jan 22;8(1):1327. doi: 10.1038/s41598-018-19460-5.

12.

Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens.

Jiménez de Oya N, De Giovanni M, Fioravanti J, Übelhart R, Di Lucia P, Fiocchi A, Iacovelli S, Efremov DG, Caligaris-Cappio F, Jumaa H, Ghia P, Guidotti LG, Iannacone M.

EMBO Mol Med. 2017 Nov;9(11):1482-1490. doi: 10.15252/emmm.201707732.

13.

The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex.

Dolezal E, Infantino S, Drepper F, Börsig T, Singh A, Wossning T, Fiala GJ, Minguet S, Warscheid B, Tarlinton DM, Jumaa H, Medgyesi D, Reth M.

Nat Immunol. 2017 Aug;18(8):911-920. doi: 10.1038/ni.3774. Epub 2017 Jun 19.

PMID:
28628091
14.

Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development.

Tsiantoulas D, Kiss M, Bartolini-Gritti B, Bergthaler A, Mallat Z, Jumaa H, Binder CJ.

Sci Rep. 2017 Jun 14;7(1):3540. doi: 10.1038/s41598-017-03688-8.

15.

Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia.

Minici C, Gounari M, Übelhart R, Scarfò L, Dühren-von Minden M, Schneider D, Tasdogan A, Alkhatib A, Agathangelidis A, Ntoufa S, Chiorazzi N, Jumaa H, Stamatopoulos K, Ghia P, Degano M.

Nat Commun. 2017 Jun 9;8:15746. doi: 10.1038/ncomms15746.

16.

CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor.

Becker M, Hobeika E, Jumaa H, Reth M, Maity PC.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5231-5236. doi: 10.1073/pnas.1621512114. Epub 2017 May 1.

17.

Dangerous fusions: a path to cancer for arrested lymphoid progenitors.

Alsadeq A, Jumaa H.

EMBO J. 2017 Mar 15;36(6):705-706. doi: 10.15252/embj.201796686. Epub 2017 Mar 8. No abstract available.

18.

Spleen Tyrosine Kinase Is Involved in the CD38 Signal Transduction Pathway in Chronic Lymphocytic Leukemia.

Benkisser-Petersen M, Buchner M, Dörffel A, Dühren-von-Minden M, Claus R, Kläsener K, Leberecht K, Burger M, Dierks C, Jumaa H, Malavasi F, Reth M, Veelken H, Duyster J, Zirlik K.

PLoS One. 2016 Dec 30;11(12):e0169159. doi: 10.1371/journal.pone.0169159. eCollection 2016.

19.

Control of B Cell Responsiveness by Isotype and Structural Elements of the Antigen Receptor.

Hobeika E, Maity PC, Jumaa H.

Trends Immunol. 2016 May;37(5):310-320. doi: 10.1016/j.it.2016.03.004. Epub 2016 Apr 1. Review.

PMID:
27052149
20.

PTEN opposes negative selection and enables oncogenic transformation of pre-B cells.

Shojaee S, Chan LN, Buchner M, Cazzaniga V, Cosgun KN, Geng H, Qiu YH, von Minden MD, Ernst T, Hochhaus A, Cazzaniga G, Melnick A, Kornblau SM, Graeber TG, Wu H, Jumaa H, Müschen M.

Nat Med. 2016 Apr;22(4):379-87. doi: 10.1038/nm.4062. Epub 2016 Mar 14.

21.

Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M.

Nature. 2016 Jun 2;534(7605):138. doi: 10.1038/nature16997. Epub 2016 Mar 9. No abstract available.

PMID:
26958840
22.

Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition.

Köhrer S, Havranek O, Seyfried F, Hurtz C, Coffey GP, Kim E, Ten Hacken E, Jäger U, Vanura K, O'Brien S, Thomas DA, Kantarjian H, Ghosh D, Wang Z, Zhang M, Ma W, Jumaa H, Debatin KM, Müschen M, Meyer LH, Davis RE, Burger JA.

Leukemia. 2016 Jun;30(6):1246-54. doi: 10.1038/leu.2016.9. Epub 2016 Feb 5.

23.

Activation loop phosphorylation regulates B-Raf in vivo and transformation by B-Raf mutants.

Köhler M, Röring M, Schorch B, Heilmann K, Stickel N, Fiala GJ, Schmitt LC, Braun S, Ehrenfeld S, Uhl FM, Kaltenbacher T, Weinberg F, Herzog S, Zeiser R, Schamel WW, Jumaa H, Brummer T.

EMBO J. 2016 Jan 18;35(2):143-61. doi: 10.15252/embj.201592097. Epub 2015 Dec 10.

24.

Tuning B cell responsiveness by antigen receptor isotype.

Jumaa H.

Oncotarget. 2015 Oct 20;6(32):32311-2. doi: 10.18632/oncotarget.4880. No abstract available.

25.

Assembly and Function of the Precursor B-Cell Receptor.

Übelhart R, Werner M, Jumaa H.

Curr Top Microbiol Immunol. 2016;393:3-25. doi: 10.1007/82_2015_475. Review.

PMID:
26415650
26.

B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation.

Maity PC, Blount A, Jumaa H, Ronneberger O, Lillemeier BF, Reth M.

Sci Signal. 2015 Sep 15;8(394):ra93. doi: 10.1126/scisignal.2005887.

PMID:
26373673
27.

Autoreactivity and the positive selection of B cells.

Übelhart R, Jumaa H.

Eur J Immunol. 2015 Nov;45(11):2971-7. doi: 10.1002/eji.201444622. Epub 2015 Sep 9. Review.

28.

Erratum: Responsiveness of B cells is regulated by the hinge region of IgD.

Übelhart R, Hug E, Bach MP, Wossning T, Minden MD, Horn AH, Tsiantoulas D, Kometani K, Kurosaki T, Binder CJ, Sticht H, Nitschke L, Reth M, Jumaa H.

Nat Immunol. 2015 Jul;16(7):785. doi: 10.1038/ni0715-785d. No abstract available.

PMID:
26086144
29.

A Conditional Knockout Mouse Model Reveals That Calponin-3 Is Dispensable for Early B Cell Development.

Flemming A, Huang QQ, Jin JP, Jumaa H, Herzog S.

PLoS One. 2015 Jun 5;10(6):e0128385. doi: 10.1371/journal.pone.0128385. eCollection 2015.

30.

Responsiveness of B cells is regulated by the hinge region of IgD.

Übelhart R, Hug E, Bach MP, Wossning T, Dühren-von Minden M, Horn AH, Tsiantoulas D, Kometani K, Kurosaki T, Binder CJ, Sticht H, Nitschke L, Reth M, Jumaa H.

Nat Immunol. 2015 May;16(5):534-43. doi: 10.1038/ni.3141. Epub 2015 Apr 6. Erratum in: Nat Immunol. 2015 Jul;16(7):785.

PMID:
25848865
31.

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M.

Nature. 2015 May 21;521(7552):357-61. doi: 10.1038/nature14231. Epub 2015 Mar 23. Erratum in: Nature. 2016 Jun 2;534(7605):138.

32.

Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma.

Schneider D, Dühren-von Minden M, Alkhatib A, Setz C, van Bergen CA, Benkißer-Petersen M, Wilhelm I, Villringer S, Krysov S, Packham G, Zirlik K, Römer W, Buske C, Stevenson FK, Veelken H, Jumaa H.

Blood. 2015 May 21;125(21):3287-96. doi: 10.1182/blood-2014-11-609404. Epub 2015 Mar 17.

33.

Antibody repertoire diversification through VH gene replacement in mice cloned from an IgA plasma cell.

Kumar R, Bach MP, Mainoldi F, Maruya M, Kishigami S, Jumaa H, Wakayama T, Kanagawa O, Fagarasan S, Casola S.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E450-7. doi: 10.1073/pnas.1417988112. Epub 2015 Jan 21.

34.

Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.

Iacovelli S, Hug E, Bennardo S, Duehren-von Minden M, Gobessi S, Rinaldi A, Suljagic M, Bilbao D, Bolasco G, Eckl-Dorna J, Niederberger V, Autore F, Sica S, Laurenti L, Wang H, Cornall RJ, Clarke SH, Croce CM, Bertoni F, Jumaa H, Efremov DG.

Blood. 2015 Mar 5;125(10):1578-88. doi: 10.1182/blood-2014-07-587790. Epub 2015 Jan 6.

35.

Depletion of STAT5 blocks TEL-SYK-induced APMF-type leukemia with myelofibrosis and myelodysplasia in mice.

Sprissler C, Belenki D, Maurer H, Aumann K, Pfeifer D, Klein C, Müller TA, Kissel S, Hülsdünker J, Alexandrovski J, Brummer T, Jumaa H, Duyster J, Dierks C.

Blood Cancer J. 2014 Aug 22;4:e240. doi: 10.1038/bcj.2014.53.

36.

Deletion of serine/arginine-rich splicing factor 3 in hepatocytes predisposes to hepatocellular carcinoma in mice.

Sen S, Langiewicz M, Jumaa H, Webster NJ.

Hepatology. 2015 Jan;61(1):171-83. doi: 10.1002/hep.27380. Epub 2014 Nov 25.

37.

The role of BCR isotype in B-cell development and activation.

Surova E, Jumaa H.

Adv Immunol. 2014;123:101-39. doi: 10.1016/B978-0-12-800266-7.00003-0. Review.

PMID:
24840949
38.

PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).

Decker S, Finter J, Forde AJ, Kissel S, Schwaller J, Mack TS, Kuhn A, Gray N, Follo M, Jumaa H, Burger M, Zirlik K, Pfeifer D, Miduturu CV, Eibel H, Veelken H, Dierks C.

Mol Cancer Ther. 2014 May;13(5):1231-45. doi: 10.1158/1535-7163.MCT-13-0575-T. Epub 2014 Mar 21.

39.

[Autoreactivity in B cell development].

Bach MP, Schneider D, Jumaa H.

Z Rheumatol. 2014 Feb;73(1):62-4. doi: 10.1007/s00393-013-1234-6. German. No abstract available.

PMID:
24554257
40.

Premature terminal differentiation protects from deregulated lymphocyte activation by ITK-Syk.

Bach MP, Hug E, Werner M, Holch J, Sprissler C, Pechloff K, Zirlik K, Zeiser R, Dierks C, Ruland J, Jumaa H.

J Immunol. 2014 Feb 1;192(3):1024-33. doi: 10.4049/jimmunol.1300420. Epub 2013 Dec 27.

41.

Inducible expression of hyperactive Syk in B cells activates Blimp-1-dependent terminal differentiation.

Hug E, Hobeika E, Reth M, Jumaa H.

Oncogene. 2014 Jul 10;33(28):3730-41. doi: 10.1038/onc.2013.326. Epub 2013 Aug 19.

PMID:
23955076
42.

Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia.

Yaktapour N, Übelhart R, Schüler J, Aumann K, Dierks C, Burger M, Pfeifer D, Jumaa H, Veelken H, Brummer T, Zirlik K.

Blood. 2013 Aug 29;122(9):1621-33. doi: 10.1182/blood-2013-02-484386. Epub 2013 Jul 17.

43.

Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function.

Sen S, Jumaa H, Webster NJ.

Nat Commun. 2013;4:1336. doi: 10.1038/ncomms2342.

44.

SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia.

Ramezani-Rad P, Geng H, Hurtz C, Chan LN, Chen Z, Jumaa H, Melnick A, Paietta E, Carroll WL, Willman CL, Lefebvre V, Müschen M.

Blood. 2013 Jan 3;121(1):148-55. doi: 10.1182/blood-2012-05-428938. Epub 2012 Nov 14.

45.

Highly restricted usage of Ig H chain VH14 family gene segments in Slp65-deficient pre-B cell leukemia in mice.

Ta VB, de Bruijn MJ, Matheson L, Zoller M, Bach MP, Wardemann H, Jumaa H, Corcoran A, Hendriks RW.

J Immunol. 2012 Nov 15;189(10):4842-51. doi: 10.4049/jimmunol.1201440. Epub 2012 Oct 12.

46.

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling.

Dühren-von Minden M, Übelhart R, Schneider D, Wossning T, Bach MP, Buchner M, Hofmann D, Surova E, Follo M, Köhler F, Wardemann H, Zirlik K, Veelken H, Jumaa H.

Nature. 2012 Sep 13;489(7415):309-12. doi: 10.1038/nature11309.

PMID:
22885698
47.

DOCKing innate to adaptive signaling for persistent antibody production.

Werner M, Jumaa H.

Nat Immunol. 2012 May 18;13(6):525-6. doi: 10.1038/ni.2317. No abstract available.

PMID:
22610240
48.

Self-recognition and clonal selection: autoreactivity drives the generation of B cells.

Herzog S, Jumaa H.

Curr Opin Immunol. 2012 Apr;24(2):166-72. doi: 10.1016/j.coi.2012.02.004. Epub 2012 Mar 5. Review.

PMID:
22398125
49.

FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination.

Alkhatib A, Werner M, Hug E, Herzog S, Eschbach C, Faraidun H, Köhler F, Wossning T, Jumaa H.

J Exp Med. 2012 Feb 13;209(2):395-406. doi: 10.1084/jem.20110216. Epub 2012 Jan 30.

50.

Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases.

Linka RM, Risse SL, Bienemann K, Werner M, Linka Y, Krux F, Synaeve C, Deenen R, Ginzel S, Dvorsky R, Gombert M, Halenius A, Hartig R, Helminen M, Fischer A, Stepensky P, Vettenranta K, Köhrer K, Ahmadian MR, Laws HJ, Fleckenstein B, Jumaa H, Latour S, Schraven B, Borkhardt A.

Leukemia. 2012 May;26(5):963-71. doi: 10.1038/leu.2011.371. Epub 2012 Jan 6.

PMID:
22289921

Supplemental Content

Support Center