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Items: 1 to 50 of 663

1.

Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25.

McLeod B, Miura K, Scally SW, Bosch A, Nguyen N, Shin H, Kim D, Volkmuth W, Rämisch S, Chichester JA, Streatfield S, Woods C, Schief WR, Emerling D, King CR, Julien JP.

Nat Commun. 2019 Sep 24;10(1):4328. doi: 10.1038/s41467-019-11980-6.

2.

Secondary structure of caveolins: a mini review.

Root KT, Julien JA, Glover KJ.

Biochem Soc Trans. 2019 Sep 24. pii: BST20190375. doi: 10.1042/BST20190375. [Epub ahead of print] Review.

PMID:
31551358
3.

Antibodies against Plasmodium falciparum malaria at the molecular level.

Julien JP, Wardemann H.

Nat Rev Immunol. 2019 Aug 28. doi: 10.1038/s41577-019-0209-5. [Epub ahead of print] Review.

PMID:
31462718
4.

Cholesterol Interaction Directly Enhances Intrinsic Activity of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

Chin S, Ramjeesingh M, Hung M, Ereño-Oreba J, Cui H, Laselva O, Julien JP, Bear CE.

Cells. 2019 Jul 31;8(8). pii: E804. doi: 10.3390/cells8080804.

5.

Key role of UBQLN2 in pathogenesis of amyotrophic lateral sclerosis and frontotemporal dementia.

Renaud L, Picher-Martel V, Codron P, Julien JP.

Acta Neuropathol Commun. 2019 Jul 18;7(1):103. doi: 10.1186/s40478-019-0758-7. Review.

6.

N-Linked Glycosylation Regulates CD22 Organization and Function.

Wasim L, Buhari FHM, Yoganathan M, Sicard T, Ereño-Orbea J, Julien JP, Treanor B.

Front Immunol. 2019 Apr 4;10:699. doi: 10.3389/fimmu.2019.00699. eCollection 2019.

7.

Strain- or Stress-Sensing in Mechanochemical Patterning by the Phytohormone Auxin.

Julien JD, Pumir A, Boudaoud A.

Bull Math Biol. 2019 Aug;81(8):3342-3361. doi: 10.1007/s11538-019-00600-5. Epub 2019 Mar 22.

PMID:
30903593
8.

Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.

Raman S, Beilschmidt M, To M, Lin K, Lui F, Jmeian Y, Ng M, Fernandez M, Fu Y, Mascall K, Duque A, Wang X, Pan G, Angers S, Moffat J, Sidhu SS, Magram J, Sinclair AM, Fransson J, Julien JP.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6812-6817. doi: 10.1073/pnas.1817246116. Epub 2019 Mar 20.

9.

Virus-mediated delivery of antibody targeting TAR DNA-binding protein-43 mitigates associated neuropathology.

Pozzi S, Thammisetty SS, Codron P, Rahimian R, Plourde KV, Soucy G, Bareil C, Phaneuf D, Kriz J, Gravel C, Julien JP.

J Clin Invest. 2019 Feb 25;129(4):1581-1595. doi: 10.1172/JCI123931. eCollection 2019 Feb 25.

10.

The toxin MPTP generates similar cognitive and locomotor deficits in hTau and tau knock-out mice.

Gratuze M, Josset N, Petry FR, Pflieger M, Eyoum Jong L, Truchetti G, Poitras I, Julien J, Bezeau F, Morin F, Samadi P, Cicchetti F, Bretzner F, Planel E.

Brain Res. 2019 May 15;1711:106-114. doi: 10.1016/j.brainres.2019.01.016. Epub 2019 Jan 11.

PMID:
30641037
11.

Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions.

Carravilla P, Chojnacki J, Rujas E, Insausti S, Largo E, Waithe D, Apellaniz B, Sicard T, Julien JP, Eggeling C, Nieva JL.

Nat Commun. 2019 Jan 8;10(1):78. doi: 10.1038/s41467-018-07962-9.

12.

Correction: The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

Joseph JD, Darimont B, Zhou W, Arrazate A, Young A, Ingalla E, Walter K, Blake RA, Nonomiya J, Guan Z, Kategaya L, Govek SP, Lai AG, Kahraman M, Brigham D, Sensintaffar J, Lu N, Shao G, Qian J, Grillot K, Moon M, Prudente R, Bischoff E, Lee KJ, Bonnefous C, Douglas KL, Julien JD, Nagasawa JY, Aparicio A, Kaufman J, Haley B, Giltnane JM, Wertz IE, Lackner MR, Nannini MA, Sampath D, Schwarz L, Manning HC, Tantawy MN, Arteaga CL, Heyman RA, Rix PJ, Friedman L, Smith ND, Metcalfe C, Hager JH.

Elife. 2019 Jan 7;8. pii: e44851. doi: 10.7554/eLife.44851.

13.

Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen-resistant breast cancer xenograft.

Govek SP, Bonnefous C, Julien JD, Nagasawa JY, Kahraman M, Lai AG, Douglas KL, Aparicio AM, Darimont BD, Grillot KL, Joseph JD, Kaufman JA, Lee KJ, Lu N, Moon MJ, Prudente RY, Sensintaffar J, Rix PJ, Hager JH, Smith ND.

Bioorg Med Chem Lett. 2019 Feb 1;29(3):367-372. doi: 10.1016/j.bmcl.2018.12.042. Epub 2018 Dec 19.

PMID:
30587451
14.

Fireproofing of domestic upholstered furniture: Migration of flame retardants and potential risks.

Lounis M, Leconte S, Rousselle C, Belzunces LP, Desauziers V, Lopez-Cuesta JM, Julien JM, Guenot D, Bourgeois D.

J Hazard Mater. 2019 Mar 15;366:556-562. doi: 10.1016/j.jhazmat.2018.11.110. Epub 2018 Dec 4.

PMID:
30572295
15.

Local Acceleration of Neurofilament Transport at Nodes of Ranvier.

Walker CL, Uchida A, Li Y, Trivedi N, Fenn JD, Monsma PC, Lariviére RC, Julien JP, Jung P, Brown A.

J Neurosci. 2019 Jan 23;39(4):663-677. doi: 10.1523/JNEUROSCI.2272-18.2018. Epub 2018 Dec 12.

16.

Neuronal Expression of UBQLN2P497H Exacerbates TDP-43 Pathology in TDP-43G348C Mice through Interaction with Ubiquitin.

Picher-Martel V, Renaud L, Bareil C, Julien JP.

Mol Neurobiol. 2019 Jul;56(7):4680-4696. doi: 10.1007/s12035-018-1411-3. Epub 2018 Oct 30.

17.

Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.

Kundu P, Semesi A, Jore MM, Morin MJ, Price VL, Liang A, Li J, Miura K, Sauerwein RW, King CR, Julien JP.

Nat Commun. 2018 Oct 26;9(1):4458. doi: 10.1038/s41467-018-06742-9.

18.

Oscillatory fluid flow drives scaling of contraction wave with system size.

Julien JD, Alim K.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10612-10617. doi: 10.1073/pnas.1805981115. Epub 2018 Oct 3.

19.

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis.

Paré B, Lehmann M, Beaudin M, Nordström U, Saikali S, Julien JP, Gilthorpe JD, Marklund SL, Cashman NR, Andersen PM, Forsberg K, Dupré N, Gould P, Brännström T, Gros-Louis F.

Sci Rep. 2018 Sep 21;8(1):14223. doi: 10.1038/s41598-018-31773-z.

20.

Body size information in large-scale acoustic bat databases.

Penone C, Kerbiriou C, Julien JF, Marmet J, Le Viol I.

PeerJ. 2018 Aug 24;6:e5370. doi: 10.7717/peerj.5370. eCollection 2018.

21.

Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors.

Yuan A, Veeranna, Sershen H, Basavarajappa BS, Smiley JF, Hashim A, Bleiwas C, Berg M, Guifoyle DN, Subbanna S, Darji S, Kumar A, Rao MV, Wilson DA, Julien JP, Javitt DC, Nixon RA.

Transl Psychiatry. 2018 Aug 24;8(1):167. doi: 10.1038/s41398-018-0194-7.

22.

Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis.

Dutta K, Patel P, Julien JP.

Exp Neurol. 2018 Nov;309:193-204. doi: 10.1016/j.expneurol.2018.08.008. Epub 2018 Aug 19.

23.

Symmetry Breaking in Spore Germination Relies on an Interplay between Polar Cap Stability and Spore Wall Mechanics.

Bonazzi D, Julien JD, Romao M, Seddiki R, Piel M, Boudaoud A, Minc N.

Dev Cell. 2018 Aug 6;46(3):388. doi: 10.1016/j.devcel.2018.07.018. No abstract available.

24.

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques.

Ereño-Orbea J, Sicard T, Cui H, Akula I, Julien JP.

J Vis Exp. 2018 Jul 5;(137). doi: 10.3791/57750.

25.

Deletion of the Fanconi Anemia C Gene in Mice Leads to Skeletal Anomalies and Defective Bone Mineralization and Microarchitecture.

Mazon M, Julien J, Ung RV, Picard S, Hamoudi D, Tam R, Filiatrault J, Frenette J, Mac-Way F, Carreau M.

J Bone Miner Res. 2018 Nov;33(11):2007-2020. doi: 10.1002/jbmr.3546. Epub 2018 Aug 8.

PMID:
29989666
26.

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.

Imkeller K, Scally SW, Bosch A, Martí GP, Costa G, Triller G, Murugan R, Renna V, Jumaa H, Kremsner PG, Sim BKL, Hoffman SL, Mordmüller B, Levashina EA, Julien JP, Wardemann H.

Science. 2018 Jun 22;360(6395):1358-1362. doi: 10.1126/science.aar5304. Epub 2018 Jun 7.

27.

Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis.

Pozzi S, Thammisetty SS, Julien JP.

Neurotherapeutics. 2018 Jul;15(3):715-727. doi: 10.1007/s13311-018-0634-3.

28.

Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies.

Scally SW, Julien JP.

Immunity. 2018 May 15;48(5):851-854. doi: 10.1016/j.immuni.2018.04.037.

29.

Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11.

Moyo T, Ereño-Orbea J, Jacob RA, Pavillet CE, Kariuki SM, Tangie EN, Julien JP, Dorfman JR.

J Virol. 2018 Jun 29;92(14). pii: e02261-17. doi: 10.1128/JVI.02261-17. Print 2018 Jul 15.

30.

How Public Health Accreditation Helped One Local Health Department Integrate and Promote Health Equity.

Wooten WJ, Julien JA, Werth J.

J Public Health Manag Pract. 2018 May/Jun;24 Suppl 3:S60-S65. doi: 10.1097/PHH.0000000000000777. No abstract available.

PMID:
29595602
31.

MIP diversity from Trichoderma: Structural considerations and transcriptional modulation during mycoparasitic association with Fusarium solani olive trees.

Ben Amira M, Mom R, Lopez D, Chaar H, Khouaja A, Pujade-Renaud V, Fumanal B, Gousset-Dupont A, Bronner G, Label P, Julien JL, Triki MA, Auguin D, Venisse JS.

PLoS One. 2018 Mar 15;13(3):e0193760. doi: 10.1371/journal.pone.0193760. eCollection 2018.

32.

PtxtPME1 and homogalacturonans influence xylem hydraulic properties in poplar.

Allario T, Tixier A, Awad H, Lemaire C, Brunel N, Badel E, Barigah TS, Julien JL, Peyret P, Mellerowicz EJ, Cochard H, Herbette S.

Physiol Plant. 2018 Aug;163(4):502-515. doi: 10.1111/ppl.12702. Epub 2018 Apr 23.

PMID:
29412468
33.

Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments.

Ereño-Orbea J, Sicard T, Cui H, Carson J, Hermans P, Julien JP.

J Mol Biol. 2018 Feb 2;430(3):322-336. doi: 10.1016/j.jmb.2017.12.010. Epub 2017 Dec 22.

PMID:
29277294
34.

Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.

Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GA, La Fontaine A, Maios C, Liao M, Ciura S, Wen XY, Rafuse V, Ichida J, Zinman L, Julien JP, Kabashi E, Robitaille R, Korngut L, Parker JA, Drapeau P.

JCI Insight. 2017 Nov 16;2(22). pii: 97152. doi: 10.1172/jci.insight.97152. eCollection 2017 Nov 16.

35.

Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.

Triller G, Scally SW, Costa G, Pissarev M, Kreschel C, Bosch A, Marois E, Sack BK, Murugan R, Salman AM, Janse CJ, Khan SM, Kappe SHI, Adegnika AA, Mordmüller B, Levashina EA, Julien JP, Wardemann H.

Immunity. 2017 Dec 19;47(6):1197-1209.e10. doi: 10.1016/j.immuni.2017.11.007. Epub 2017 Nov 29.

36.

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.

Scally SW, Murugan R, Bosch A, Triller G, Costa G, Mordmüller B, Kremsner PG, Sim BKL, Hoffman SL, Levashina EA, Wardemann H, Julien JP.

J Exp Med. 2018 Jan 2;215(1):63-75. doi: 10.1084/jem.20170869. Epub 2017 Nov 22.

37.

Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.

Scally SW, McLeod B, Bosch A, Miura K, Liang Q, Carroll S, Reponen S, Nguyen N, Giladi E, Rämisch S, Yusibov V, Bradley A, Lemiale F, Schief WR, Emerling D, Kellam P, King CR, Julien JP.

Nat Commun. 2017 Nov 16;8(1):1568. doi: 10.1038/s41467-017-01924-3.

38.

Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons.

Komatsu K, Imamura K, Yamashita H, Julien JP, Takahashi R, Inoue H.

Neuroreport. 2018 Jan 3;29(1):25-29. doi: 10.1097/WNR.0000000000000922.

PMID:
29140847
39.

Molecular basis of human CD22 function and therapeutic targeting.

Ereño-Orbea J, Sicard T, Cui H, Mazhab-Jafari MT, Benlekbir S, Guarné A, Rubinstein JL, Julien JP.

Nat Commun. 2017 Oct 2;8(1):764. doi: 10.1038/s41467-017-00836-6.

40.

Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants.

Gupta P, Zhang Z, Sugiman-Marangos SN, Tam J, Raman S, Julien JP, Kroh HK, Lacy DB, Murgolo N, Bekkari K, Therien AG, Hernandez LD, Melnyk RA.

J Biol Chem. 2017 Oct 20;292(42):17290-17301. doi: 10.1074/jbc.M117.806687. Epub 2017 Aug 23.

41.

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.

Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, Cottrell CA, Torres JL, Vavourakis CD, van Gils MJ, LaBranche C, Montefiori DC, Desaire H, Crispin M, Klasse PJ, Lee KK, Moore JP, Ward AB, Wilson IA, Sanders RW.

Cell Rep. 2017 Aug 22;20(8):1805-1817. doi: 10.1016/j.celrep.2017.07.077.

42.

Highlighting the differences in post-traumatic symptoms between patients with complicated and uncomplicated mild traumatic brain injury and injured controls.

Julien J, Tinawi S, Anderson K, Frenette LC, Audrit H, Ferland MC, Feyz M, De Guise E.

Brain Inj. 2017;31(13-14):1846-1855. doi: 10.1080/02699052.2017.1346289. Epub 2017 Aug 17.

PMID:
28816563
43.

Differential effects of voluntary treadmill exercise and caloric restriction on tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology fed with Western diet.

Gratuze M, Julien J, Morin F, Marette A, Planel E.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):452-461. doi: 10.1016/j.pnpbp.2017.08.001. Epub 2017 Aug 3.

PMID:
28779908
44.

Considering Postoperative Functional Hypoaldosteronism after Unilateral Adrenalectomy.

Starker LF, Christakis I, Julien JS, Schwarz K, Graham P, Grubbs EG, Lee JE, Perrier ND.

Am Surg. 2017 Jun 1;83(6):598-604.

PMID:
28637561
45.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H.

Sci Transl Med. 2017 May 24;9(391). pii: eaaf3962. doi: 10.1126/scitranslmed.aaf3962.

46.

Association of traumatic brain injury and Alzheimer disease onset: A systematic review.

Julien J, Joubert S, Ferland MC, Frenette LC, Boudreau-Duhaime MM, Malo-Véronneau L, de Guise E.

Ann Phys Rehabil Med. 2017 Sep;60(5):347-356. doi: 10.1016/j.rehab.2017.03.009. Epub 2017 May 11. Review.

47.

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.

Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, Wilson IA, Burton DR, Ward AB.

Immunity. 2017 Apr 18;46(4):690-702. doi: 10.1016/j.immuni.2017.03.017.

48.

Correction: Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PPL, Julien JP, Hirano N.

J Immunol. 2017 May 1;198(9):3757. doi: 10.4049/jimmunol.1700296. No abstract available.

49.

Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer's disease-like tau pathology.

Gratuze M, Julien J, Petry FR, Morin F, Planel E.

Sci Rep. 2017 Apr 12;7:46359. doi: 10.1038/srep46359.

50.

Project SafeFoodPack Design: case study on indirect migration from paper and boards.

Nguyen PM, Julien JM, Breysse C, Lyathaud C, Thébault J, Vitrac O.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Oct;34(10):1703-1720. doi: 10.1080/19440049.2017.1315777. Epub 2017 Apr 25.

PMID:
28374636

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