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Items: 1 to 50 of 648

1.

Neuronal Expression of UBQLN2P497H Exacerbates TDP-43 Pathology in TDP-43G348C Mice through Interaction with Ubiquitin.

Picher-Martel V, Renaud L, Bareil C, Julien JP.

Mol Neurobiol. 2018 Oct 30. doi: 10.1007/s12035-018-1411-3. [Epub ahead of print]

PMID:
30377984
2.

Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.

Kundu P, Semesi A, Jore MM, Morin MJ, Price VL, Liang A, Li J, Miura K, Sauerwein RW, King CR, Julien JP.

Nat Commun. 2018 Oct 26;9(1):4458. doi: 10.1038/s41467-018-06742-9.

3.

Oscillatory fluid flow drives scaling of contraction wave with system size.

Julien JD, Alim K.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):10612-10617. doi: 10.1073/pnas.1805981115. Epub 2018 Oct 3.

PMID:
30282737
4.

Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis.

Paré B, Lehmann M, Beaudin M, Nordström U, Saikali S, Julien JP, Gilthorpe JD, Marklund SL, Cashman NR, Andersen PM, Forsberg K, Dupré N, Gould P, Brännström T, Gros-Louis F.

Sci Rep. 2018 Sep 21;8(1):14223. doi: 10.1038/s41598-018-31773-z.

5.

Body size information in large-scale acoustic bat databases.

Penone C, Kerbiriou C, Julien JF, Marmet J, Le Viol I.

PeerJ. 2018 Aug 24;6:e5370. doi: 10.7717/peerj.5370. eCollection 2018.

6.

Neurofilament light interaction with GluN1 modulates neurotransmission and schizophrenia-associated behaviors.

Yuan A, Veeranna, Sershen H, Basavarajappa BS, Smiley JF, Hashim A, Bleiwas C, Berg M, Guifoyle DN, Subbanna S, Darji S, Kumar A, Rao MV, Wilson DA, Julien JP, Javitt DC, Nixon RA.

Transl Psychiatry. 2018 Aug 24;8(1):167. doi: 10.1038/s41398-018-0194-7.

7.

Protective effects of Withania somnifera extract in SOD1G93A mouse model of amyotrophic lateral sclerosis.

Dutta K, Patel P, Julien JP.

Exp Neurol. 2018 Nov;309:193-204. doi: 10.1016/j.expneurol.2018.08.008. Epub 2018 Aug 19.

8.

Symmetry Breaking in Spore Germination Relies on an Interplay between Polar Cap Stability and Spore Wall Mechanics.

Bonazzi D, Julien JD, Romao M, Seddiki R, Piel M, Boudaoud A, Minc N.

Dev Cell. 2018 Aug 6;46(3):388. doi: 10.1016/j.devcel.2018.07.018. No abstract available.

PMID:
30086305
9.

Characterization of Glycoproteins with the Immunoglobulin Fold by X-Ray Crystallography and Biophysical Techniques.

Ereño-Orbea J, Sicard T, Cui H, Akula I, Julien JP.

J Vis Exp. 2018 Jul 5;(137). doi: 10.3791/57750.

10.

Deletion of the Fanconi Anemia C Gene in Mice Leads to Skeletal Anomalies and Defective Bone Mineralization and Microarchitecture.

Mazon M, Julien J, Ung RV, Picard S, Hamoudi D, Tam R, Filiatrault J, Frenette J, Mac-Way F, Carreau M.

J Bone Miner Res. 2018 Nov;33(11):2007-2020. doi: 10.1002/jbmr.3546. Epub 2018 Aug 8.

PMID:
29989666
11.

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.

Imkeller K, Scally SW, Bosch A, Martí GP, Costa G, Triller G, Murugan R, Renna V, Jumaa H, Kremsner PG, Sim BKL, Hoffman SL, Mordmüller B, Levashina EA, Julien JP, Wardemann H.

Science. 2018 Jun 22;360(6395):1358-1362. doi: 10.1126/science.aar5304. Epub 2018 Jun 7.

PMID:
29880723
12.

Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis.

Pozzi S, Thammisetty SS, Julien JP.

Neurotherapeutics. 2018 Jul;15(3):715-727. doi: 10.1007/s13311-018-0634-3.

13.

Peek-Peak-Pique: Repeating Motifs of Subtle Variance Are Targets for Potent Malaria Antibodies.

Scally SW, Julien JP.

Immunity. 2018 May 15;48(5):851-854. doi: 10.1016/j.immuni.2018.04.037.

PMID:
29768173
14.

Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11.

Moyo T, Ereño-Orbea J, Jacob RA, Pavillet CE, Kariuki SM, Tangie EN, Julien JP, Dorfman JR.

J Virol. 2018 Jun 29;92(14). pii: e02261-17. doi: 10.1128/JVI.02261-17. Print 2018 Jul 15.

PMID:
29618644
15.

How Public Health Accreditation Helped One Local Health Department Integrate and Promote Health Equity.

Wooten WJ, Julien JA, Werth J.

J Public Health Manag Pract. 2018 May/Jun;24 Suppl 3 Supplement:S60-S65. doi: 10.1097/PHH.0000000000000777. No abstract available.

PMID:
29595602
16.

MIP diversity from Trichoderma: Structural considerations and transcriptional modulation during mycoparasitic association with Fusarium solani olive trees.

Ben Amira M, Mom R, Lopez D, Chaar H, Khouaja A, Pujade-Renaud V, Fumanal B, Gousset-Dupont A, Bronner G, Label P, Julien JL, Triki MA, Auguin D, Venisse JS.

PLoS One. 2018 Mar 15;13(3):e0193760. doi: 10.1371/journal.pone.0193760. eCollection 2018.

17.

PtxtPME1 and homogalacturonans influence xylem hydraulic properties in poplar.

Allario T, Tixier A, Awad H, Lemaire C, Brunel N, Badel E, Barigah TS, Julien JL, Peyret P, Mellerowicz EJ, Cochard H, Herbette S.

Physiol Plant. 2018 Aug;163(4):502-515. doi: 10.1111/ppl.12702. Epub 2018 Apr 23.

PMID:
29412468
18.

Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments.

Ereño-Orbea J, Sicard T, Cui H, Carson J, Hermans P, Julien JP.

J Mol Biol. 2018 Feb 2;430(3):322-336. doi: 10.1016/j.jmb.2017.12.010. Epub 2017 Dec 22.

PMID:
29277294
19.

Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.

Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GA, La Fontaine A, Maios C, Liao M, Ciura S, Wen XY, Rafuse V, Ichida J, Zinman L, Julien JP, Kabashi E, Robitaille R, Korngut L, Parker JA, Drapeau P.

JCI Insight. 2017 Nov 16;2(22). pii: 97152. doi: 10.1172/jci.insight.97152. [Epub ahead of print]

20.

Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.

Triller G, Scally SW, Costa G, Pissarev M, Kreschel C, Bosch A, Marois E, Sack BK, Murugan R, Salman AM, Janse CJ, Khan SM, Kappe SHI, Adegnika AA, Mordmüller B, Levashina EA, Julien JP, Wardemann H.

Immunity. 2017 Dec 19;47(6):1197-1209.e10. doi: 10.1016/j.immuni.2017.11.007. Epub 2017 Nov 29.

PMID:
29195810
21.

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.

Scally SW, Murugan R, Bosch A, Triller G, Costa G, Mordmüller B, Kremsner PG, Sim BKL, Hoffman SL, Levashina EA, Wardemann H, Julien JP.

J Exp Med. 2018 Jan 2;215(1):63-75. doi: 10.1084/jem.20170869. Epub 2017 Nov 22.

22.

Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.

Scally SW, McLeod B, Bosch A, Miura K, Liang Q, Carroll S, Reponen S, Nguyen N, Giladi E, Rämisch S, Yusibov V, Bradley A, Lemiale F, Schief WR, Emerling D, Kellam P, King CR, Julien JP.

Nat Commun. 2017 Nov 16;8(1):1568. doi: 10.1038/s41467-017-01924-3.

23.

Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons.

Komatsu K, Imamura K, Yamashita H, Julien JP, Takahashi R, Inoue H.

Neuroreport. 2018 Jan 3;29(1):25-29. doi: 10.1097/WNR.0000000000000922.

PMID:
29140847
24.

Molecular basis of human CD22 function and therapeutic targeting.

Ereño-Orbea J, Sicard T, Cui H, Mazhab-Jafari MT, Benlekbir S, Guarné A, Rubinstein JL, Julien JP.

Nat Commun. 2017 Oct 2;8(1):764. doi: 10.1038/s41467-017-00836-6.

25.

Functional defects in Clostridium difficile TcdB toxin uptake identify CSPG4 receptor-binding determinants.

Gupta P, Zhang Z, Sugiman-Marangos SN, Tam J, Raman S, Julien JP, Kroh HK, Lacy DB, Murgolo N, Bekkari K, Therien AG, Hernandez LD, Melnyk RA.

J Biol Chem. 2017 Oct 20;292(42):17290-17301. doi: 10.1074/jbc.M117.806687. Epub 2017 Aug 23.

26.

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.

Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, Cottrell CA, Torres JL, Vavourakis CD, van Gils MJ, LaBranche C, Montefiori DC, Desaire H, Crispin M, Klasse PJ, Lee KK, Moore JP, Ward AB, Wilson IA, Sanders RW.

Cell Rep. 2017 Aug 22;20(8):1805-1817. doi: 10.1016/j.celrep.2017.07.077.

27.

Highlighting the differences in post-traumatic symptoms between patients with complicated and uncomplicated mild traumatic brain injury and injured controls.

Julien J, Tinawi S, Anderson K, Frenette LC, Audrit H, Ferland MC, Feyz M, De Guise E.

Brain Inj. 2017;31(13-14):1846-1855. doi: 10.1080/02699052.2017.1346289. Epub 2017 Aug 17.

PMID:
28816563
28.

Differential effects of voluntary treadmill exercise and caloric restriction on tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology fed with Western diet.

Gratuze M, Julien J, Morin F, Marette A, Planel E.

Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):452-461. doi: 10.1016/j.pnpbp.2017.08.001. Epub 2017 Aug 3.

PMID:
28779908
29.

Considering Postoperative Functional Hypoaldosteronism after Unilateral Adrenalectomy.

Starker LF, Christakis I, Julien JS, Schwarz K, Graham P, Grubbs EG, Lee JE, Perrier ND.

Am Surg. 2017 Jun 1;83(6):598-604.

PMID:
28637561
30.

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, Kunath T, Wray S, Furuya H, Era T, Makioka K, Okamoto K, Fujisawa T, Nishitoh H, Homma K, Ichijo H, Julien JP, Obata N, Hosokawa M, Akiyama H, Kaneko S, Ayaki T, Ito H, Kaji R, Takahashi R, Yamanaka S, Inoue H.

Sci Transl Med. 2017 May 24;9(391). pii: eaaf3962. doi: 10.1126/scitranslmed.aaf3962.

PMID:
28539470
31.

Association of traumatic brain injury and Alzheimer disease onset: A systematic review.

Julien J, Joubert S, Ferland MC, Frenette LC, Boudreau-Duhaime MM, Malo-Véronneau L, de Guise E.

Ann Phys Rehabil Med. 2017 Sep;60(5):347-356. doi: 10.1016/j.rehab.2017.03.009. Epub 2017 May 11. Review.

32.

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.

Lee JH, Andrabi R, Su CY, Yasmeen A, Julien JP, Kong L, Wu NC, McBride R, Sok D, Pauthner M, Cottrell CA, Nieusma T, Blattner C, Paulson JC, Klasse PJ, Wilson IA, Burton DR, Ward AB.

Immunity. 2017 Apr 18;46(4):690-702. doi: 10.1016/j.immuni.2017.03.017.

33.

Correction: Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PPL, Julien JP, Hirano N.

J Immunol. 2017 May 1;198(9):3757. doi: 10.4049/jimmunol.1700296. No abstract available.

34.

Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer's disease-like tau pathology.

Gratuze M, Julien J, Petry FR, Morin F, Planel E.

Sci Rep. 2017 Apr 12;7:46359. doi: 10.1038/srep46359.

35.

Project SafeFoodPack Design: case study on indirect migration from paper and boards.

Nguyen PM, Julien JM, Breysse C, Lyathaud C, Thébault J, Vitrac O.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 Oct;34(10):1703-1720. doi: 10.1080/19440049.2017.1315777. Epub 2017 Apr 25.

PMID:
28374636
36.

Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis.

Ohta Y, Soucy G, Phaneuf D, Audet JN, Gros-Louis F, Rouleau GA, Blasco H, Corcia P, Andersen PM, Nordin F, Yamashita T, Abe K, Julien JP.

Hum Mol Genet. 2016 Nov 1;25(21):4771-4786. doi: 10.1093/hmg/ddw304.

37.

Antithrombotic agents intake prior to injury does not affect outcome after a traumatic brain injury in hospitalized elderly patients.

Julien J, Alsideiri G, Marcoux J, Hasen M, Correa JA, Feyz M, Maleki M, de Guise E.

J Clin Neurosci. 2017 Apr;38:122-125. doi: 10.1016/j.jocn.2016.12.032. Epub 2017 Jan 16.

PMID:
28110930
38.

Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.

Chamoto K, Guo T, Scally SW, Kagoya Y, Anczurowski M, Wang CH, Rahman MA, Saso K, Butler MO, Chiu PP, Julien JP, Hirano N.

J Immunol. 2017 Feb 1;198(3):1056-1065. doi: 10.4049/jimmunol.1601556. Epub 2016 Dec 21. Erratum in: J Immunol. 2017 May 1;198(9):3757.

39.

Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.

Dutta K, Patel P, Rahimian R, Phaneuf D, Julien JP.

Neurotherapeutics. 2017 Apr;14(2):447-462. doi: 10.1007/s13311-016-0499-2.

40.

Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming.

Cruz Tleugabulova M, Escalante NK, Deng S, Fieve S, Ereño-Orbea J, Savage PB, Julien JP, Mallevaey T.

J Immunol. 2016 Nov 15;197(10):3959-3969. Epub 2016 Oct 19.

41.

Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy.

Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, Julien JP, Goldman RD, Opal P.

Hum Mol Genet. 2016 Jun 1;25(11):2143-2157. Epub 2016 Mar 21.

42.

High-fat, high-sugar, and high-cholesterol consumption does not impact tau pathogenesis in a mouse model of Alzheimer's disease-like tau pathology.

Gratuze M, Julien J, Morin F, Calon F, Hébert SS, Marette A, Planel E.

Neurobiol Aging. 2016 Nov;47:71-73. doi: 10.1016/j.neurobiolaging.2016.07.016. Epub 2016 Jul 29.

PMID:
27565300
43.

Exosome secretion is a key pathway for clearance of pathological TDP-43.

Iguchi Y, Eid L, Parent M, Soucy G, Bareil C, Riku Y, Kawai K, Takagi S, Yoshida M, Katsuno M, Sobue G, Julien JP.

Brain. 2016 Dec;139(Pt 12):3187-3201. Epub 2016 Sep 27.

44.

Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.

Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EM, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, Pauthner M, Saye-Francisco KL, Sesterhenn F, Wilson PC, Galloway DA, Stanfield RL, Wilson IA, Burton DR, Schief WR.

PLoS Pathog. 2016 Sep 14;12(9):e1005905. doi: 10.1371/journal.ppat.1005905. eCollection 2016 Sep.

45.

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.

Jardine JG, Sok D, Julien JP, Briney B, Sarkar A, Liang CH, Scherer EA, Henry Dunand CJ, Adachi Y, Diwanji D, Hsueh J, Jones M, Kalyuzhniy O, Kubitz M, Spencer S, Pauthner M, Saye-Francisco KL, Sesterhenn F, Wilson PC, Galloway DM, Stanfield RL, Wilson IA, Burton DR, Schief WR.

PLoS Pathog. 2016 Aug 25;12(8):e1005815. doi: 10.1371/journal.ppat.1005815. eCollection 2016 Aug. Erratum in: PLoS Pathog. 2016 Sep;12(9):e1005905.

46.

The structural basis of modified nucleosome recognition by 53BP1.

Wilson MD, Benlekbir S, Fradet-Turcotte A, Sherker A, Julien JP, McEwan A, Noordermeer SM, Sicheri F, Rubinstein JL, Durocher D.

Nature. 2016 Aug 4;536(7614):100-3. Epub 2016 Jul 27.

PMID:
27462807
47.

Cell division plane orientation based on tensile stress in Arabidopsis thaliana.

Louveaux M, Julien JD, Mirabet V, Boudaoud A, Hamant O.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4294-303. doi: 10.1073/pnas.1600677113. Epub 2016 Jul 19.

48.

The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer.

Joseph JD, Darimont B, Zhou W, Arrazate A, Young A, Ingalla E, Walter K, Blake RA, Nonomiya J, Guan Z, Kategaya L, Govek SP, Lai AG, Kahraman M, Brigham D, Sensintaffar J, Lu N, Shao G, Qian J, Grillot K, Moon M, Prudente R, Bischoff E, Lee KJ, Bonnefous C, Douglas KL, Julien JD, Nagasawa JY, Aparicio A, Kaufman J, Haley B, Giltnane JM, Wertz IE, Lackner MR, Nannini MA, Sampath D, Schwarz L, Manning HC, Tantawy MN, Arteaga CL, Heyman RA, Rix PJ, Friedman L, Smith ND, Metcalfe C, Hager JH.

Elife. 2016 Jul 13;5. pii: e15828. doi: 10.7554/eLife.15828.

49.

From animal models to human disease: a genetic approach for personalized medicine in ALS.

Picher-Martel V, Valdmanis PN, Gould PV, Julien JP, Dupré N.

Acta Neuropathol Commun. 2016 Jul 11;4(1):70. doi: 10.1186/s40478-016-0340-5. Review.

50.

Mechanical Stress Induces Remodeling of Vascular Networks in Growing Leaves.

Bar-Sinai Y, Julien JD, Sharon E, Armon S, Nakayama N, Adda-Bedia M, Boudaoud A.

PLoS Comput Biol. 2016 Apr 13;12(4):e1004819. doi: 10.1371/journal.pcbi.1004819. eCollection 2016 Apr.

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