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Items: 23

1.

Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides.

Du L, Risinger AL, Mitchell CA, You J, Stamps BW, Pan N, King JB, Bopassa JC, Judge SIV, Yang Z, Stevenson BS, Cichewicz RH.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E8957-E8966. doi: 10.1073/pnas.1707565114. Epub 2017 Oct 10.

2.

TrkB agonist, 7,8-dihydroxyflavone, reduces the clinical and pathological severity of a murine model of multiple sclerosis.

Makar TK, Nimmagadda VK, Singh IS, Lam K, Mubariz F, Judge SI, Trisler D, Bever CT Jr.

J Neuroimmunol. 2016 Mar 15;292:9-20. doi: 10.1016/j.jneuroim.2016.01.002. Epub 2016 Jan 6.

PMID:
26943953
3.

Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets.

Nimmagadda VK, Bever CT, Vattikunta NR, Talat S, Ahmad V, Nagalla NK, Trisler D, Judge SI, Royal W 3rd, Chandrasekaran K, Russell JW, Makar TK.

J Immunol. 2013 May 1;190(9):4595-607. doi: 10.4049/jimmunol.1202584. Epub 2013 Apr 1.

4.

Use of engineered bone marrow stem cells to deliver brain derived neurotrophic factor under the control of a tetracycline sensitive response element in experimental allergic encephalomyelitis.

Makar TK, Nimmagadda VK, Patibandla GK, Le T, Judge SI, Trisler D, Bever CT.

J Neuroimmunol. 2012 Nov 15;252(1-2):1-15. doi: 10.1016/j.jneuroim.2012.07.005. Epub 2012 Aug 17.

PMID:
22901507
5.

C5b-9-activated, K(v)1.3 channels mediate oligodendrocyte cell cycle activation and dedifferentiation.

Tegla CA, Cudrici C, Rozycka M, Soloviova K, Ito T, Singh AK, Khan A, Azimzadeh P, Andrian-Albescu M, Khan A, Niculescu F, Rus V, Judge SI, Rus H.

Exp Mol Pathol. 2011 Aug;91(1):335-45. doi: 10.1016/j.yexmp.2011.04.006. Epub 2011 Apr 22.

6.

Sustained-release fampridine for multiple sclerosis.

Bever CT, Judge SI.

Expert Opin Investig Drugs. 2009 Jul;18(7):1013-24. doi: 10.1517/13543780903002082. Review. Erratum in: Expert Opin Investig Drugs. 2009 Aug;18(8):1241.

PMID:
19548855
7.

Patents related to therapeutic activation of K(ATP) and K(2P) potassium channels for neuroprotection: ischemic/hypoxic/anoxic injury and general anesthetics.

Judge SI, Smith PJ.

Expert Opin Ther Pat. 2009 Apr;19(4):433-60. doi: 10.1517/13543770902765151. Review.

PMID:
19441925
8.

The human WW45 protein enhances MST1-mediated apoptosis in vivo.

Luo X, Li Z, Yan Q, Li X, Tao D, Wang J, Leng Y, Gardner K, Judge SI, Li QQ, Hu J, Gong J.

Int J Mol Med. 2009 Mar;23(3):357-62.

9.

Potassium channel blockers and openers as CNS neurologic therapeutic agents.

Judge SI, Smith PJ, Stewart PE, Bever CT Jr.

Recent Pat CNS Drug Discov. 2007 Nov;2(3):200-28. Review.

PMID:
18221232
10.

Dendritic cells are abundant in non-lesional gray matter in multiple sclerosis.

Cudrici C, Ito T, Zafranskaia E, Niculescu F, Mullen KM, Vlaicu S, Judge SI, Calabresi PA, Rus H.

Exp Mol Pathol. 2007 Oct;83(2):198-206. Epub 2007 Jul 6.

11.

Timing of apoptosis onset depends on cell cycle progression in peripheral blood lymphocytes and lymphocytic leukemia cells.

Feng Y, Wu J, Feng X, Tao D, Hu J, Qin J, Li X, Xiao W, Gardner K, Judge SI, Li QQ, Gong J.

Oncol Rep. 2007 Jun;17(6):1437-44.

PMID:
17487402
12.

Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts.

You Y, Geng X, Zhao P, Fu Z, Wang C, Chao S, Liu N, Lu A, Gardner K, Pu P, Kong C, Ge Y, Judge SI, Li QQ.

Cell Mol Life Sci. 2007 Mar;64(5):621-31.

PMID:
17310280
13.

Unscheduled CDK1 activity in G1 phase of the cell cycle triggers apoptosis in X-irradiated lymphocytic leukemia cells.

Wu J, Feng Y, Xie D, Li X, Xiao W, Tao D, Qin J, Hu J, Gardner K, Judge SI, Li QQ, Gong J.

Cell Mol Life Sci. 2006 Nov;63(21):2538-45.

PMID:
17013563
14.
15.

Potassium channels Kv1.3 and Kv1.5 are expressed on blood-derived dendritic cells in the central nervous system.

Mullen KM, Rozycka M, Rus H, Hu L, Cudrici C, Zafranskaia E, Pennington MW, Johns DC, Judge SI, Calabresi PA.

Ann Neurol. 2006 Jul;60(1):118-27.

PMID:
16729292
16.

Potassium channel blockers in multiple sclerosis: neuronal Kv channels and effects of symptomatic treatment.

Judge SI, Bever CT Jr.

Pharmacol Ther. 2006 Jul;111(1):224-59. Epub 2006 Feb 9. Review.

PMID:
16472864
17.

The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.

Rus H, Pardo CA, Hu L, Darrah E, Cudrici C, Niculescu T, Niculescu F, Mullen KM, Allie R, Guo L, Wulff H, Beeton C, Judge SI, Kerr DA, Knaus HG, Chandy KG, Calabresi PA.

Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11094-9. Epub 2005 Jul 25.

18.
19.

Induction of RANTES chemokine expression in human astrocytic cells is dependent upon activation of NF-kappaB transcription factor.

Li QQ, Bever CT, Burt DR, Judge SI, Trisler GD.

Int J Mol Med. 2001 May;7(5):527-33.

PMID:
11295116
20.

Inactivation gating and 4-AP sensitivity in human brain Kv1.4 potassium channel.

Judge SI, Monteiro MJ, Yeh JZ, Bever CT.

Brain Res. 1999 Jun 12;831(1-2):43-54.

PMID:
10411982
21.

Potassium Channel Blockers Inhibit Adoptive Transfer of Experimental Allergic Encephalomyelitis by Myelin-Basic-Protein-Stimulated Rat T Lymphocytes.

Judge SI, Yeh JZ, Mannie MD, Pope Seifert L, Paterson PY.

J Biomed Sci. 1997 Jul-Aug;4(4):169-178.

PMID:
11725150
23.

IKir regulation in murine macrophages: whole cell and perforated patch studies.

Judge SI, Montcalm-Mazzilli E, Gallin EK.

Am J Physiol. 1994 Dec;267(6 Pt 1):C1691-8.

PMID:
7810612

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