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Items: 1 to 50 of 56

1.

An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.

Futch HS, McFarland KN, Moore BD, Kuhn MZ, Giasson BI, Ladd TB, Scott KA, Shapiro MR, Nosacka RL, Goodwin MS, Ran Y, Cruz PE, Ryu DH, Croft CL, Levites Y, Janus C, Chakrabarty P, Judge AR, Brusko TM, de Kloet AD, Krause EG, Golde TE.

J Exp Med. 2019 Aug 29. pii: jem.20190430. doi: 10.1084/jem.20190430. [Epub ahead of print]

PMID:
31467037
2.

Racial and ethnic disparities in a state-wide registry of patients with pancreatic cancer and an exploratory investigation of cancer cachexia as a contributor to observed inequities.

Permuth JB, Clark Daly A, Jeong D, Choi JW, Cameron ME, Chen DT, Teer JK, Barnett TE, Li J, Powers BD, Kumar NB, George TJ, Ali KN, Huynh T, Vyas S, Gwede CK, Simmons VN, Hodul PJ, Carballido EM, Judge AR, Fleming JB, Merchant N, Trevino JG.

Cancer Med. 2019 Jun;8(6):3314-3324. doi: 10.1002/cam4.2180. Epub 2019 May 9.

3.

Colon 26 adenocarcinoma (C26)-induced cancer cachexia impairs skeletal muscle mitochondrial function and content.

Neyroud D, Nosacka RL, Judge AR, Hepple RT.

J Muscle Res Cell Motil. 2019 Mar;40(1):59-65. doi: 10.1007/s10974-019-09510-4. Epub 2019 Apr 3.

PMID:
30945134
4.

MYOD1 functions as a clock amplifier as well as a critical co-factor for downstream circadian gene expression in muscle.

Hodge BA, Zhang X, Gutierrez-Monreal MA, Cao Y, Hammers DW, Yao Z, Wolff CA, Du P, Kemler D, Judge AR, Esser KA.

Elife. 2019 Feb 21;8. pii: e43017. doi: 10.7554/eLife.43017.

5.

Skeletal Muscle Fibrosis in Pancreatic Cancer Patients with Respect to Survival.

Judge SM, Nosacka RL, Delitto D, Gerber MH, Cameron ME, Trevino JG, Judge AR.

JNCI Cancer Spectr. 2018 Jul;2(3):pky043. doi: 10.1093/jncics/pky043. Epub 2018 Aug 6.

6.

Local and Systemic Cytokine Profiling for Pancreatic Ductal Adenocarcinoma to Study Cancer Cachexia in an Era of Precision Medicine.

Gerber MH, Underwood PW, Judge SM, Delitto D, Delitto AE, Nosacka RL, DiVita BB, Thomas RM, Permuth JB, Hughes SJ, Wallet SM, Judge AR, Trevino JG.

Int J Mol Sci. 2018 Dec 1;19(12). pii: E3836. doi: 10.3390/ijms19123836.

7.

Mas Receptor Activation Slows Tumor Growth and Attenuates Muscle Wasting in Cancer.

Murphy KT, Hossain MI, Swiderski K, Chee A, Naim T, Trieu J, Haynes V, Read SJ, Stapleton DI, Judge SM, Trevino JG, Judge AR, Lynch GS.

Cancer Res. 2019 Feb 15;79(4):706-719. doi: 10.1158/0008-5472.CAN-18-1207. Epub 2018 Nov 12.

PMID:
30420474
8.

Cancer cachexia impairs neural respiratory drive in hypoxia but not hypercapnia.

Fields DP, Roberts BM, Simon AK, Judge AR, Fuller DD, Mitchell GS.

J Cachexia Sarcopenia Muscle. 2019 Feb;10(1):63-72. doi: 10.1002/jcsm.12348. Epub 2018 Oct 25.

9.

Tumour-derived leukaemia inhibitory factor is a major driver of cancer cachexia and morbidity in C26 tumour-bearing mice.

Kandarian SC, Nosacka RL, Delitto AE, Judge AR, Judge SM, Ganey JD, Moreira JD, Jackman RW.

J Cachexia Sarcopenia Muscle. 2018 Dec;9(6):1109-1120. doi: 10.1002/jcsm.12346. Epub 2018 Sep 30.

10.

Cold shock protein RBM3 attenuates atrophy and induces hypertrophy in skeletal muscle.

Van Pelt DW, Confides AL, Judge AR, Vanderklish PW, Dupont-Versteegden EE.

J Muscle Res Cell Motil. 2018 Apr;39(1-2):35-40. doi: 10.1007/s10974-018-9496-x. Epub 2018 Jul 26.

PMID:
30051360
11.

Orthotopic Patient-Derived Pancreatic Cancer Xenografts Engraft Into the Pancreatic Parenchyma, Metastasize, and Induce Muscle Wasting to Recapitulate the Human Disease.

Go KL, Delitto D, Judge SM, Gerber MH, George TJ Jr, Behrns KE, Hughes SJ, Judge AR, Trevino JG.

Pancreas. 2017 Jul;46(6):813-819. doi: 10.1097/MPA.0000000000000843.

PMID:
28609371
12.

Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation.

Ahn B, Coblentz PD, Beharry AW, Patel N, Judge AR, Moylan JS, Hoopes CW, Bonnell MR, Ferreira LF.

Front Physiol. 2017 Jan 9;7:686. doi: 10.3389/fphys.2016.00686. eCollection 2016.

13.

A clinically applicable muscular index predicts long-term survival in resectable pancreatic cancer.

Delitto D, Judge SM, George TJ Jr, Sarosi GA, Thomas RM, Behrns KE, Hughes SJ, Judge AR, Trevino JG.

Surgery. 2017 Apr;161(4):930-938. doi: 10.1016/j.surg.2016.09.038. Epub 2016 Dec 5.

PMID:
27932030
14.

Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia.

Delitto D, Judge SM, Delitto AE, Nosacka RL, Rocha FG, DiVita BB, Gerber MH, George TJ Jr, Behrns KE, Hughes SJ, Wallet SM, Judge AR, Trevino JG.

Oncotarget. 2017 Jan 3;8(1):1177-1189. doi: 10.18632/oncotarget.13593.

15.

Janus kinase inhibition prevents cancer- and myocardial infarction-mediated diaphragm muscle weakness in mice.

Smith IJ, Roberts B, Beharry A, Godinez GL, Payan DG, Kinsella TM, Judge AR, Ferreira LF.

Am J Physiol Regul Integr Comp Physiol. 2016 Apr 15;310(8):R707-10. doi: 10.1152/ajpregu.00550.2015. Epub 2016 Feb 10.

16.

Forelimb muscle plasticity following unilateral cervical spinal cord injury.

Gonzalez-Rothi EJ, Armstrong GT, Cerreta AJ, Fitzpatrick GM, Reier PJ, Lane MA, Judge AR, Fuller DD.

Muscle Nerve. 2016 Mar;53(3):475-8. doi: 10.1002/mus.25007.

17.

Differential expression of HDAC and HAT genes in atrophying skeletal muscle.

Beharry AW, Judge AR.

Muscle Nerve. 2015 Dec;52(6):1098-101. doi: 10.1002/mus.24912. Epub 2015 Oct 10.

18.

Identification of the Acetylation and Ubiquitin-Modified Proteome during the Progression of Skeletal Muscle Atrophy.

Ryder DJ, Judge SM, Beharry AW, Farnsworth CL, Silva JC, Judge AR.

PLoS One. 2015 Aug 24;10(8):e0136247. doi: 10.1371/journal.pone.0136247. eCollection 2015.

19.

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

Ahn B, Beharry AW, Frye GS, Judge AR, Ferreira LF.

Am J Physiol Lung Cell Mol Physiol. 2015 Sep 1;309(5):L497-505. doi: 10.1152/ajplung.00176.2015. Epub 2015 Jul 24.

20.

Genome-wide identification of FoxO-dependent gene networks in skeletal muscle during C26 cancer cachexia.

Judge SM, Wu CL, Beharry AW, Roberts BM, Ferreira LF, Kandarian SC, Judge AR.

BMC Cancer. 2014 Dec 24;14:997. doi: 10.1186/1471-2407-14-997.

21.

Rebuttal from Michael B. Reid, Andrew R. Judge and Sue C. Bodine.

Reid MB, Judge AR, Bodine SC.

J Physiol. 2014 Dec 15;592(24):5351. doi: 10.1113/jphysiol.2014.284398. No abstract available.

22.

CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis.

Reid MB, Judge AR, Bodine SC.

J Physiol. 2014 Dec 15;592(24):5345-7. doi: 10.1113/jphysiol.2014.279406. No abstract available.

23.

Transcriptional regulation of myotrophic actions by testosterone and trenbolone on androgen-responsive muscle.

Ye F, McCoy SC, Ross HH, Bernardo JA, Beharry AW, Senf SM, Judge AR, Beck DT, Conover CF, Cannady DF, Smith BK, Yarrow JF, Borst SE.

Steroids. 2014 Sep;87:59-66. doi: 10.1016/j.steroids.2014.05.024. Epub 2014 Jun 10.

PMID:
24928725
24.

HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy.

Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, Judge AR.

J Cell Sci. 2014 Apr 1;127(Pt 7):1441-53. doi: 10.1242/jcs.136390. Epub 2014 Jan 24.

25.

Rapid diaphragm atrophy following cervical spinal cord hemisection.

Gill LC, Ross HH, Lee KZ, Gonzalez-Rothi EJ, Dougherty BJ, Judge AR, Fuller DD.

Respir Physiol Neurobiol. 2014 Feb 1;192:66-73. doi: 10.1016/j.resp.2013.12.006. Epub 2013 Dec 14.

26.

Cancer cachexia decreases specific force and accelerates fatigue in limb muscle.

Roberts BM, Frye GS, Ahn B, Ferreira LF, Judge AR.

Biochem Biophys Res Commun. 2013 Jun 7;435(3):488-92. doi: 10.1016/j.bbrc.2013.05.018. Epub 2013 May 11.

27.

Skeletal muscle interleukin-6 regulation in hyperthermia.

Welc SS, Judge AR, Clanton TL.

Am J Physiol Cell Physiol. 2013 Aug 15;305(4):C406-13. doi: 10.1152/ajpcell.00084.2013. Epub 2013 May 1.

28.

Loss of the inducible Hsp70 delays the inflammatory response to skeletal muscle injury and severely impairs muscle regeneration.

Senf SM, Howard TM, Ahn B, Ferreira LF, Judge AR.

PLoS One. 2013 Apr 23;8(4):e62687. doi: 10.1371/journal.pone.0062687. Print 2013.

29.

Diaphragm atrophy and contractile dysfunction in a murine model of pulmonary hypertension.

Ahn B, Empinado HM, Al-Rajhi M, Judge AR, Ferreira LF.

PLoS One. 2013 Apr 22;8(4):e62702. doi: 10.1371/journal.pone.0062702. Print 2013.

30.

Diaphragm and ventilatory dysfunction during cancer cachexia.

Roberts BM, Ahn B, Smuder AJ, Al-Rajhi M, Gill LC, Beharry AW, Powers SK, Fuller DD, Ferreira LF, Judge AR.

FASEB J. 2013 Jul;27(7):2600-10. doi: 10.1096/fj.12-222844. Epub 2013 Mar 20.

31.

Meeting synopsis: advances in skeletal muscle biology in health and disease (gainesville, Florida, february 22nd to 24th 2012) - day 2: "muscle diseases and regeneration" and "clinical/translational research".

Judge AR, Powers SK, Ferreira LF, Bamman MM.

Front Physiol. 2012 Jun 11;3:201. doi: 10.3389/fphys.2012.00201. eCollection 2012. No abstract available.

33.

Oxidative stress and disuse muscle atrophy: cause or consequence?

Powers SK, Smuder AJ, Judge AR.

Curr Opin Clin Nutr Metab Care. 2012 May;15(3):240-5. doi: 10.1097/MCO.0b013e328352b4c2. Review.

34.

Putting the spice in weaning*.

Falk DJ, Judge AR.

Crit Care Med. 2012 Mar;40(3):1022-3. doi: 10.1097/CCM.0b013e31823e96c2. No abstract available. Erratum in: Crit Care Med. 2012 May;40(5):1697.

PMID:
22343867
35.

Determination of gene promoter activity in skeletal muscles in vivo.

Senf SM, Judge AR.

Methods Mol Biol. 2012;798:461-72. doi: 10.1007/978-1-61779-343-1_27.

PMID:
22130854
36.

Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy.

Reed SA, Sandesara PB, Senf SM, Judge AR.

FASEB J. 2012 Mar;26(3):987-1000. doi: 10.1096/fj.11-189977. Epub 2011 Nov 18.

37.

Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy.

Xu J, Hwang JC, Lees HA, Wohlgemuth SE, Knutson MD, Judge AR, Dupont-Versteegden EE, Marzetti E, Leeuwenburgh C.

Exp Gerontol. 2012 Jan;47(1):100-8. doi: 10.1016/j.exger.2011.10.011. Epub 2011 Nov 4.

38.

p300 Acetyltransferase activity differentially regulates the localization and activity of the FOXO homologues in skeletal muscle.

Senf SM, Sandesara PB, Reed SA, Judge AR.

Am J Physiol Cell Physiol. 2011 Jun;300(6):C1490-501. doi: 10.1152/ajpcell.00255.2010. Epub 2011 Mar 9.

39.

Inhibition of IkappaB kinase alpha (IKKα) or IKKbeta (IKKβ) plus forkhead box O (Foxo) abolishes skeletal muscle atrophy.

Reed SA, Senf SM, Cornwell EW, Kandarian SC, Judge AR.

Biochem Biophys Res Commun. 2011 Feb 18;405(3):491-6. doi: 10.1016/j.bbrc.2011.01.059. Epub 2011 Jan 21.

40.

IκBα degradation is necessary for skeletal muscle atrophy associated with contractile claudication.

Hain BA, Dodd SL, Judge AR.

Am J Physiol Regul Integr Comp Physiol. 2011 Mar;300(3):R595-604. doi: 10.1152/ajpregu.00728.2010. Epub 2011 Jan 5.

41.

Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy.

Buford TW, Anton SD, Judge AR, Marzetti E, Wohlgemuth SE, Carter CS, Leeuwenburgh C, Pahor M, Manini TM.

Ageing Res Rev. 2010 Oct;9(4):369-83. doi: 10.1016/j.arr.2010.04.004. Epub 2010 May 14. Review.

42.

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting.

McClung JM, Judge AR, Powers SK, Yan Z.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C542-9. doi: 10.1152/ajpcell.00192.2009. Epub 2009 Dec 2.

43.

FOXO signaling is required for disuse muscle atrophy and is directly regulated by Hsp70.

Senf SM, Dodd SL, Judge AR.

Am J Physiol Cell Physiol. 2010 Jan;298(1):C38-45. doi: 10.1152/ajpcell.00315.2009. Epub 2009 Oct 28.

44.

Ros-mediated activation of NF-kappaB and Foxo during muscle disuse.

Dodd SL, Gagnon BJ, Senf SM, Hain BA, Judge AR.

Muscle Nerve. 2010 Jan;41(1):110-3. doi: 10.1002/mus.21526.

45.

Hsp27 inhibits IKKbeta-induced NF-kappaB activity and skeletal muscle atrophy.

Dodd SL, Hain B, Senf SM, Judge AR.

FASEB J. 2009 Oct;23(10):3415-23. doi: 10.1096/fj.08-124602. Epub 2009 Jun 15.

46.

Calpain-1 is required for hydrogen peroxide-induced myotube atrophy.

McClung JM, Judge AR, Talbert EE, Powers SK.

Am J Physiol Cell Physiol. 2009 Feb;296(2):C363-71. doi: 10.1152/ajpcell.00497.2008. Epub 2008 Dec 24.

47.

Hsp70 overexpression inhibits NF-kappaB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy.

Senf SM, Dodd SL, McClung JM, Judge AR.

FASEB J. 2008 Nov;22(11):3836-45. doi: 10.1096/fj.08-110163. Epub 2008 Jul 21.

48.

The myopathy of peripheral arterial occlusive disease: Part 2. Oxidative stress, neuropathy, and shift in muscle fiber type.

Pipinos II, Judge AR, Selsby JT, Zhu Z, Swanson SA, Nella AA, Dodd SL.

Vasc Endovascular Surg. 2008 Apr-May;42(2):101-12. doi: 10.1177/1538574408315995. Epub 2008 Apr 7. Review.

PMID:
18390972
49.

Antioxidants attenuate oxidative damage in rat skeletal muscle during mild ischaemia.

Judge AR, Selsby JT, Dodd SL.

Exp Physiol. 2008 Apr;93(4):479-85. doi: 10.1113/expphysiol.2007.040972. Epub 2008 Jan 25.

50.

The myopathy of peripheral arterial occlusive disease: part 1. Functional and histomorphological changes and evidence for mitochondrial dysfunction.

Pipinos II, Judge AR, Selsby JT, Zhu Z, Swanson SA, Nella AA, Dodd SL.

Vasc Endovascular Surg. 2007 Dec-2008 Jan;41(6):481-9. doi: 10.1177/1538574407311106. Review.

PMID:
18166628

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