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Items: 12


HMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma.

Pellegrini L, Xue J, Larson D, Pastorino S, Jube S, Forest KH, Saad-Jube ZS, Napolitano A, Pagano I, Negi VS, Bianchi ME, Morris P, Pass HI, Gaudino G, Carbone M, Yang H.

Oncotarget. 2017 Apr 4;8(14):22649-22661. doi: 10.18632/oncotarget.15152.


Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression.

Yang H, Pellegrini L, Napolitano A, Giorgi C, Jube S, Preti A, Jennings CJ, De Marchis F, Flores EG, Larson D, Pagano I, Tanji M, Powers A, Kanodia S, Gaudino G, Pastorino S, Pass HI, Pinton P, Bianchi ME, Carbone M.

Cell Death Dis. 2015 Jun 11;6:e1786. doi: 10.1038/cddis.2015.153.


Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation.

Wang L, Liu R, Ye P, Wong C, Chen GY, Zhou P, Sakabe K, Zheng X, Wu W, Zhang P, Jiang T, Bassetti MF, Jube S, Sun Y, Zhang Y, Zheng P, Liu Y.

Nat Commun. 2015 Jan 20;6:5909. doi: 10.1038/ncomms6909.


Continuous exposure to chrysotile asbestos can cause transformation of human mesothelial cells via HMGB1 and TNF-α signaling.

Qi F, Okimoto G, Jube S, Napolitano A, Pass HI, Laczko R, Demay RM, Khan G, Tiirikainen M, Rinaudo C, Croce A, Yang H, Gaudino G, Carbone M.

Am J Pathol. 2013 Nov;183(5):1654-66. doi: 10.1016/j.ajpath.2013.07.029.


CSPG4 as a target of antibody-based immunotherapy for malignant mesothelioma.

Rivera Z, Ferrone S, Wang X, Jube S, Yang H, Pass HI, Kanodia S, Gaudino G, Carbone M.

Clin Cancer Res. 2012 Oct 1;18(19):5352-63. doi: 10.1158/1078-0432.CCR-12-0628. Epub 2012 Aug 14.


Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma.

Jube S, Rivera ZS, Bianchi ME, Powers A, Wang E, Pagano I, Pass HI, Gaudino G, Carbone M, Yang H.

Cancer Res. 2012 Jul 1;72(13):3290-301. doi: 10.1158/0008-5472.CAN-11-3481. Epub 2012 May 2.


Erionite exposure in North Dakota and Turkish villages with mesothelioma.

Carbone M, Baris YI, Bertino P, Brass B, Comertpay S, Dogan AU, Gaudino G, Jube S, Kanodia S, Partridge CR, Pass HI, Rivera ZS, Steele I, Tuncer M, Way S, Yang H, Miller A.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13618-23. doi: 10.1073/pnas.1105887108. Epub 2011 Jul 25.


Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation.

Yang H, Rivera Z, Jube S, Nasu M, Bertino P, Goparaju C, Franzoso G, Lotze MT, Krausz T, Pass HI, Bianchi ME, Carbone M.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12611-6. doi: 10.1073/pnas.1006542107. Epub 2010 Jun 28.


Transgenic Leucaena leucocephala expressing the Rhizobium gene pydA encoding a meta-cleavage dioxygenase shows reduced mimosine content.

Jube SL, Borthakur D.

Plant Physiol Biochem. 2010 Apr;48(4):273-8. doi: 10.1016/j.plaphy.2010.01.005. Epub 2010 Jan 22.


Immunization with hybrid recombinant Mycobacterium tuberculosis H37Rv proteins increases the TH1 cytokine response in mice following a pulmonary instillation of irradiated mycobacteria.

Walton CB, Inos AB, Andres OA, Jube S, de Couet HG, Douglas JT, Patek PQ, Borthakur D.

Vaccine. 2008 Aug 12;26(34):4396-402. doi: 10.1016/j.vaccine.2008.05.093. Epub 2008 Jun 26.


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