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Items: 35

1.

Design of an in vitro biocatalytic cascade for the manufacture of islatravir.

Huffman MA, Fryszkowska A, Alvizo O, Borra-Garske M, Campos KR, Canada KA, Devine PN, Duan D, Forstater JH, Grosser ST, Halsey HM, Hughes GJ, Jo J, Joyce LA, Kolev JN, Liang J, Maloney KM, Mann BF, Marshall NM, McLaughlin M, Moore JC, Murphy GS, Nawrat CC, Nazor J, Novick S, Patel NR, Rodriguez-Granillo A, Robaire SA, Sherer EC, Truppo MD, Whittaker AM, Verma D, Xiao L, Xu Y, Yang H.

Science. 2019 Dec 6;366(6470):1255-1259. doi: 10.1126/science.aay8484.

PMID:
31806816
2.

Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products.

Pyser JB, Baker Dockrey SA, Benítez AR, Joyce LA, Wiscons RA, Smith JL, Narayan ARH.

J Am Chem Soc. 2019 Nov 20;141(46):18551-18559. doi: 10.1021/jacs.9b09385. Epub 2019 Nov 6.

PMID:
31692339
3.

Manipulating Solid Forms of Contact Insecticides for Infectious Disease Prevention.

Zhu X, Hu CT, Yang J, Joyce LA, Qiu M, Ward MD, Kahr B.

J Am Chem Soc. 2019 Oct 23;141(42):16858-16864. doi: 10.1021/jacs.9b08125. Epub 2019 Oct 11.

PMID:
31601104
4.

Photoexcitation of flavoenzymes enables a stereoselective radical cyclization.

Biegasiewicz KF, Cooper SJ, Gao X, Oblinsky DG, Kim JH, Garfinkle SE, Joyce LA, Sandoval BA, Scholes GD, Hyster TK.

Science. 2019 Jun 21;364(6446):1166-1169. doi: 10.1126/science.aaw1143.

5.

Peptide Oligomerization Memory Effects and Their Impact on the Physical Stability of the GLP-1 Agonist Liraglutide.

Bothe JR, Andrews A, Smith KJ, Joyce LA, Krishnamachari Y, Kashi S.

Mol Pharm. 2019 May 6;16(5):2153-2161. doi: 10.1021/acs.molpharmaceut.9b00106. Epub 2019 Apr 25.

PMID:
30990695
6.

Rhodium-Catalyzed Asymmetric Hydroamination of Allyl Amines.

Vanable EP, Kennemur JL, Joyce LA, Ruck RT, Schultz DM, Hull KL.

J Am Chem Soc. 2019 Jan 16;141(2):739-742. doi: 10.1021/jacs.8b09811. Epub 2019 Jan 7.

7.

Optical Analysis of Reaction Yield and Enantiomeric Excess: A New Paradigm Ready for Prime Time.

Herrera BT, Pilicer SL, Anslyn EV, Joyce LA, Wolf C.

J Am Chem Soc. 2018 Aug 22;140(33):10385-10401. doi: 10.1021/jacs.8b06607. Epub 2018 Aug 8.

PMID:
30059621
8.

Optical Chirality Sensing with a Stereodynamic Aluminum Biphenolate Probe.

De Los Santos ZA, Joyce LA, Sherer EC, Welch CJ, Wolf C.

J Org Chem. 2019 Apr 19;84(8):4639-4645. doi: 10.1021/acs.joc.8b01301. Epub 2018 Jul 27.

PMID:
30019902
9.

Beyond optical rotation: what's left is not always right in total synthesis.

Joyce LA, Nawrat CC, Sherer EC, Biba M, Brunskill A, Martin GE, Cohen RD, Davies IW.

Chem Sci. 2017 Oct 30;9(2):415-424. doi: 10.1039/c7sc04249c. eCollection 2018 Jan 14.

10.

Identification of ortho-Substituted Benzoic Acid/Ester Derivatives via the Gas-Phase Neighboring Group Participation Effect in (+)-ESI High Resolution Mass Spectrometry.

Blincoe WD, Rodriguez-Granillo A, Saurí J, Pierson NA, Joyce LA, Mangion I, Sheng H.

J Am Soc Mass Spectrom. 2018 Apr;29(4):694-703. doi: 10.1007/s13361-017-1884-8. Epub 2018 Feb 27.

PMID:
29488104
11.

Oxyfunctionalization of the Remote C-H Bonds of Aliphatic Amines by Decatungstate Photocatalysis.

Schultz DM, Lévesque F, DiRocco DA, Reibarkh M, Ji Y, Joyce LA, Dropinski JF, Sheng H, Sherry BD, Davies IW.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15274-15278. doi: 10.1002/anie.201707537. Epub 2017 Oct 26.

PMID:
29044797
12.

Absolute configuration assignment of (+)-fluralaner using vibrational circular dichroism.

Kong J, Joyce LA, Liu J, Jarrell TM, Culberson JC, Sherer EC.

Chirality. 2017 Dec;29(12):854-864. doi: 10.1002/chir.22770. Epub 2017 Oct 5.

PMID:
28981965
13.

Parameterization of Acyclic Diaminocarbene Ligands Applied to a Gold(I)-Catalyzed Enantioselective Tandem Rearrangement/Cyclization.

Niemeyer ZL, Pindi S, Khrakovsky DA, Kuzniewski CN, Hong CM, Joyce LA, Sigman MS, Toste FD.

J Am Chem Soc. 2017 Sep 20;139(37):12943-12946. doi: 10.1021/jacs.7b08791. Epub 2017 Sep 8.

14.

Palladium-Catalyzed Enantioselective Heck Alkenylation of Trisubstituted Allylic Alkenols: A Redox-Relay Strategy to Construct Vicinal Stereocenters.

Zhang C, Tutkowski B, DeLuca RJ, Joyce LA, Wiest O, Sigman MS.

Chem Sci. 2017 Mar 1;8(3):2277-2282. doi: 10.1039/C6SC04585E. Epub 2016 Dec 9.

15.

Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice.

Roecker AJ, Egbertson M, Jones KLG, Gomez R, Kraus RL, Li Y, Koser AJ, Urban MO, Klein R, Clements M, Panigel J, Daley C, Wang J, Finger EN, Majercak J, Santarelli V, Gregan I, Cato M, Filzen T, Jovanovska A, Wang YH, Wang D, Joyce LA, Sherer EC, Peng X, Wang X, Sun H, Coleman PJ, Houghton AK, Layton ME.

Bioorg Med Chem Lett. 2017 May 15;27(10):2087-2093. doi: 10.1016/j.bmcl.2017.03.085. Epub 2017 Mar 30.

PMID:
28389149
16.

Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular Scaffold.

Chan ST, Nani RR, Schauer EA, Martin GE, Williamson RT, Saurí J, Buevich AV, Schafer WA, Joyce LA, Goey AK, Figg WD, Ransom TT, Henrich CJ, McKee TC, Moser A, MacDonald SA, Khan S, McMahon JB, Schnermann MJ, Gustafson KR.

J Org Chem. 2016 Nov 18;81(22):10631-10640. Epub 2016 Nov 10.

17.

Ultrafast chiral separations for high throughput enantiopurity analysis.

Barhate CL, Joyce LA, Makarov AA, Zawatzky K, Bernardoni F, Schafer WA, Armstrong DW, Welch CJ, Regalado EL.

Chem Commun (Camb). 2017 Jan 3;53(3):509-512. doi: 10.1039/c6cc08512a.

PMID:
27872920
18.

Hydroxypyridyl Imines: Enhancing Chromatographic Separation and Stereochemical Analysis of Chiral Amines via Circular Dichroism.

Joyce LA, Regalado EL, Welch CJ.

J Org Chem. 2016 Sep 16;81(18):8199-205. doi: 10.1021/acs.joc.6b01162. Epub 2016 Sep 1.

PMID:
27529785
19.

Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI.

Pero JE, Rossi MA, Kelly MJ 3rd, Lehman HD, Layton ME, Garbaccio RM, O'Brien JA, Magliaro BC, Uslaner JM, Huszar SL, Fillgrove KL, Tang C, Kuo Y, Joyce LA, Sherer EC, Jacobson MA.

ACS Med Chem Lett. 2016 Jan 10;7(3):312-7. doi: 10.1021/acsmedchemlett.5b00459. eCollection 2016 Mar 10.

20.

Correction to "Chiral Conjugated Corrals".

Ball M, Fowler B, Li P, Joyce LA, Li F, Liu T, Paley D, Zhong Y, Li H, Xiao S, Ng F, Steigerwald ML, Nuckolls C.

J Am Chem Soc. 2016 Feb 24;138(7):2454. doi: 10.1021/jacs.6b00013. Epub 2016 Feb 12. No abstract available.

PMID:
26871606
21.

Antenna Biphenols: Development of Extended Wavelength Chiroptical Reporters.

Bentley KW, Joyce LA, Sherer EC, Sheng H, Wolf C, Welch CJ.

J Org Chem. 2016 Feb 5;81(3):1185-91. doi: 10.1021/acs.joc.5b02716. Epub 2016 Jan 26.

PMID:
26756165
22.

Chiral Conjugated Corrals.

Ball M, Fowler B, Li P, Joyce LA, Li F, Liu T, Paley D, Zhong Y, Li H, Xiao S, Ng F, Steigerwald ML, Nuckolls C.

J Am Chem Soc. 2015 Aug 12;137(31):9982-7. doi: 10.1021/jacs.5b05698. Epub 2015 Jul 30. Erratum in: J Am Chem Soc. 2016 Feb 24;138(7):2454.

PMID:
26225639
23.

Homodecoupled 1,1- and 1,n-ADEQUATE: Pivotal NMR Experiments for the Structure Revision of Cryptospirolepine.

Saurí J, Bermel W, Buevich AV, Sherer EC, Joyce LA, Sharaf MH, Schiff PL Jr, Parella T, Williamson RT, Martin GE.

Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10160-4. doi: 10.1002/anie.201502540. Epub 2015 Jul 15.

PMID:
26178441
24.

Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2).

Singh SB, Kaelin DE, Wu J, Miesel L, Tan CM, Black T, Nargund R, Meinke PT, Olsen DB, Lagrutta A, Lu J, Patel S, Rickert KW, Smith RF, Soisson S, Sherer E, Joyce LA, Wei C, Peng X, Wang X, Fukuda H, Kishii R, Takei M, Takano H, Shibasaki M, Yajima M, Nishimura A, Shibata T, Fukuda Y.

Bioorg Med Chem Lett. 2015 May 1;25(9):1831-5. doi: 10.1016/j.bmcl.2015.03.044. Epub 2015 Mar 24.

PMID:
25851938
25.

Detection of dehalogenation impurities in organohalogenated pharmaceuticals by UHPLC-DAD-HRESIMS.

Regalado EL, Dermenjian RK, Joyce LA, Welch CJ.

J Pharm Biomed Anal. 2014 Apr;92:1-5. doi: 10.1016/j.jpba.2013.12.043. Epub 2014 Jan 7.

PMID:
24469094
26.

Chromatographic separation and assignment of absolute configuration of hydroxywarfarin isomers.

Regalado EL, Sherer EC, Green MD, Hendersonl DW, Thomas Williamson R, Joyce LA, Welch CJ.

Chirality. 2014 Feb;26(2):95-101. doi: 10.1002/chir.22274. Epub 2013 Dec 13.

PMID:
24339228
27.

A mechanically controlled indicator displacement assay.

Sakakibara K, Joyce LA, Mori T, Fujisawa T, Shabbir SH, Hill JP, Anslyn EV, Ariga K.

Angew Chem Int Ed Engl. 2012 Sep 17;51(38):9643-6. doi: 10.1002/anie.201203402. Epub 2012 Aug 29. No abstract available.

PMID:
22930528
28.

Enantio- and chemoselective differentiation of protected α-amino acids and β-homoamino acids with a single copper(II) host.

Joyce LA, Canary JW, Anslyn EV.

Chemistry. 2012 Jun 25;18(26):8064-9. doi: 10.1002/chem.201103592. Epub 2012 May 16.

29.

A simple method for the determination of enantiomeric excess and identity of chiral carboxylic acids.

Joyce LA, Maynor MS, Dragna JM, da Cruz GM, Lynch VM, Canary JW, Anslyn EV.

J Am Chem Soc. 2011 Aug 31;133(34):13746-52. doi: 10.1021/ja205775g. Epub 2011 Aug 3. Erratum in: J Am Chem Soc. 2012 Mar 14;134(10):5004.

30.

The uses of supramolecular chemistry in synthetic methodology development: examples of anion and neutral molecular recognition.

Joyce LA, Shabbir SH, Anslyn EV.

Chem Soc Rev. 2010 Oct;39(10):3621-32. doi: 10.1039/b926224p. Epub 2010 Aug 11. Review.

PMID:
20714470
31.

Pattern-based recognition for the rapid determination of identity, concentration, and enantiomeric excess of subtly different threo diols.

Shabbir SH, Joyce LA, da Cruz GM, Lynch VM, Sorey S, Anslyn EV.

J Am Chem Soc. 2009 Sep 16;131(36):13125-31. doi: 10.1021/ja904545d.

32.

Managing for multiple resources under climate change: national forests.

Joyce LA, Blate GM, McNulty SG, Millar CI, Moser S, Neilson RP, Peterson DL.

Environ Manage. 2009 Dec;44(6):1022-32. doi: 10.1007/s00267-009-9324-6.

PMID:
19588192
33.

Practical synthesis of enantiomerically pure beta2-amino acids via proline-catalyzed diastereoselective aminomethylation of aldehydes.

Chi Y, English EP, Pomerantz WC, Horne WS, Joyce LA, Alexander LR, Fleming WS, Hopkins EA, Gellman SH.

J Am Chem Soc. 2007 May 9;129(18):6050-5. Epub 2007 Apr 17.

PMID:
17439122
34.

The interplay between climate change, forests, and disturbances.

Dale VH, Joyce LA, McNulty S, Neilson RP.

Sci Total Environ. 2000 Nov 15;262(3):201-4. Review.

PMID:
11087026
35.

Follicular growth and corpus luteum function in women with unexplained infertility, monitored by ultrasonography and measurement of daily salivary progesterone.

Finn MM, Gosling JP, Tallon DF, Joyce LA, Meehan FP, Fottrell PF.

Gynecol Endocrinol. 1989 Dec;3(4):297-308.

PMID:
2626978

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