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Items: 1 to 50 of 313

1.

Pre-aggregation kinetics and intermediates of α-synuclein monitored by the ESIPT probe 7MFE.

Fauerbach JA, Jovin TM.

Eur Biophys J. 2018 May;47(4):345-362. doi: 10.1007/s00249-017-1272-0. Epub 2017 Dec 18.

2.

ESIPT and FRET probes for monitoring nanoparticle polymer coating stability.

Azcárate JC, Díaz SA, Fauerbach JA, Gillanders F, Rubert AA, Jares-Erijman EA, Jovin TM, Fonticelli MH.

Nanoscale. 2017 Jun 29;9(25):8647-8656. doi: 10.1039/c7nr01787a.

PMID:
28612865
3.

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.

Vicente Miranda H, Szego ÉM, Oliveira LMA, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF.

Brain. 2017 May 1;140(5):1399-1419. doi: 10.1093/brain/awx056.

PMID:
28398476
4.

Water-Soluble, Thermostable, Photomodulated Color-Switching Quantum Dots.

Díaz SA, Gillanders F, Susumu K, Oh E, Medintz IL, Jovin TM.

Chemistry. 2017 Jan 5;23(2):263-267. doi: 10.1002/chem.201604688. Epub 2016 Nov 3.

PMID:
27723151
5.

Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells.

Oliveira LM, Falomir-Lockhart LJ, Botelho MG, Lin KH, Wales P, Koch JC, Gerhardt E, Taschenberger H, Outeiro TF, Lingor P, Schüle B, Arndt-Jovin DJ, Jovin TM.

Cell Death Dis. 2015 Nov 26;6:e1994. doi: 10.1038/cddis.2015.318.

6.

Conformational variability of recombination R-triplex formed by the mammalian telomeric sequence.

Shchyolkina AK, Kaluzhny DN, Borisova OF, Arndt-Jovin DJ, Jovin TM, Zhurkin VB.

J Biomol Struct Dyn. 2016 Jun;34(6):1298-306. doi: 10.1080/07391102.2015.1077344. Epub 2015 Oct 15.

7.

Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.

Koch JC, Bitow F, Haack J, d'Hedouville Z, Zhang JN, Tönges L, Michel U, Oliveira LM, Jovin TM, Liman J, Tatenhorst L, Bähr M, Lingor P.

Cell Death Dis. 2015 Jul 9;6:e1811. doi: 10.1038/cddis.2015.169.

8.

Alpha-synuclein levels in blood plasma decline with healthy aging.

Koehler NK, Stransky E, Meyer M, Gaertner S, Shing M, Schnaidt M, Celej MS, Jovin TM, Leyhe T, Laske C, Batra A, Buchkremer G, Fallgatter AJ, Wernet D, Richartz-Salzburger E.

PLoS One. 2015 Apr 6;10(4):e0123444. doi: 10.1371/journal.pone.0123444. eCollection 2015.

9.

Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation.

Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, Giese A, Kruse N, Mollenhauer B, Geiss-Friedlander R, Ludolph AC, Freischmidt A, Feiler MS, Danzer KM, Zweckstetter M, Jovin TM, Simons M, Weishaupt JH, Schneider A.

Acta Neuropathol. 2015 May;129(5):695-713. doi: 10.1007/s00401-015-1408-1. Epub 2015 Mar 17.

10.

Photoswitchable semiconductor nanocrystals with self-regulating photochromic Förster resonance energy transfer acceptors.

Díaz SA, Gillanders F, Jares-Erijman EA, Jovin TM.

Nat Commun. 2015 Jan 16;6:6036. doi: 10.1038/ncomms7036.

PMID:
25592060
11.

Mg2+-dependent conformational changes and product release during DNA-catalyzed RNA ligation monitored by Bimane fluorescence.

Turriani E, Höbartner C, Jovin TM.

Nucleic Acids Res. 2015 Jan;43(1):40-50. doi: 10.1093/nar/gku1268. Epub 2014 Dec 10.

12.

Pinning down the EGF receptor.

Jovin TM.

Biophys J. 2014 Dec 2;107(11):2486-8. doi: 10.1016/j.bpj.2014.10.037. Epub 2014 Dec 2. No abstract available.

13.

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.

Flierl A, Oliveira LM, Falomir-Lockhart LJ, Mak SK, Hesley J, Soldner F, Arndt-Jovin DJ, Jaenisch R, Langston JW, Jovin TM, Schüle B.

PLoS One. 2014 Nov 12;9(11):e112413. doi: 10.1371/journal.pone.0112413. eCollection 2014.

14.

Structure-function relationships of ErbB RTKs in the plasma membrane of living cells.

Arndt-Jovin DJ, Botelho MG, Jovin TM.

Cold Spring Harb Perspect Biol. 2014 Apr 1;6(4):a008961. doi: 10.1101/cshperspect.a008961. Review.

15.

Photoswitchable fluorescent diheteroarylethenes: substituent effects on photochromic and solvatochromic properties.

Gillanders F, Giordano L, Díaz SA, Jovin TM, Jares-Erijman EA.

Photochem Photobiol Sci. 2014 Mar;13(3):603-12. doi: 10.1039/c3pp50374g. Epub 2014 Feb 4.

PMID:
24496436
16.

Influence of gold nanoparticles on the kinetics of α-synuclein aggregation.

Alvarez YD, Fauerbach JA, Pellegrotti JV, Jovin TM, Jares-Erijman EA, Stefani FD.

Nano Lett. 2013;13(12):6156-63. doi: 10.1021/nl403490e. Epub 2013 Nov 18.

PMID:
24219503
17.

Magnetic nanoparticles as mediators of ligand-free activation of EGFR signaling.

Bharde AA, Palankar R, Fritsch C, Klaver A, Kanger JS, Jovin TM, Arndt-Jovin DJ.

PLoS One. 2013 Jul 23;8(7):e68879. doi: 10.1371/journal.pone.0068879. Print 2013.

18.

Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy.

Ziomkiewicz I, Loman A, Klement R, Fritsch C, Klymchenko AS, Bunt G, Jovin TM, Arndt-Jovin DJ.

Cytometry A. 2013 Sep;83(9):794-805. doi: 10.1002/cyto.a.22311. Epub 2013 Jul 9.

19.

Altered serum IgG levels to α-synuclein in dementia with Lewy bodies and Alzheimer's disease.

Koehler NK, Stransky E, Shing M, Gaertner S, Meyer M, Schreitmüller B, Leyhe T, Laske C, Maetzler W, Kahle P, Celej MS, Jovin TM, Fallgatter AJ, Batra A, Buchkremer G, Schott K, Richartz-Salzburger E.

PLoS One. 2013 May 31;8(5):e64649. doi: 10.1371/journal.pone.0064649. Print 2013.

20.

Quantum dots as templates for self-assembly of photoswitchable polymers: small, dual-color nanoparticles capable of facile photomodulation.

Díaz SA, Giordano L, Azcárate JC, Jovin TM, Jares-Erijman EA.

J Am Chem Soc. 2013 Feb 27;135(8):3208-17. doi: 10.1021/ja3117813. Epub 2013 Feb 13.

PMID:
23360378
21.

Biophysical properties and cellular toxicity of covalent crosslinked oligomers of α-synuclein formed by photoinduced side-chain tyrosyl radicals.

Borsarelli CD, Falomir-Lockhart LJ, Ostatná V, Fauerbach JA, Hsiao HH, Urlaub H, Paleček E, Jares-Erijman EA, Jovin TM.

Free Radic Biol Med. 2012 Aug 15;53(4):1004-15. doi: 10.1016/j.freeradbiomed.2012.06.035. Epub 2012 Jul 6.

PMID:
22771470
22.

Modulation of a photoswitchable dual-color quantum dot containing a photochromic FRET acceptor and an internal standard.

Díaz SA, Giordano L, Jovin TM, Jares-Erijman EA.

Nano Lett. 2012 Jul 11;12(7):3537-44. doi: 10.1021/nl301093s. Epub 2012 Jun 4.

PMID:
22663176
23.

Highly Solvatochromic 7-Aryl-3-hydroxychromones.

Giordano L, Shvadchak VV, Fauerbach JA, Jares-Erijman EA, Jovin TM.

J Phys Chem Lett. 2012 Apr 19;3(8):1011-6. doi: 10.1021/jz3002019. Epub 2012 Apr 3.

PMID:
26286565
24.

Imaging nanometer-sized α-synuclein aggregates by superresolution fluorescence localization microscopy.

Roberti MJ, Fölling J, Celej MS, Bossi M, Jovin TM, Jares-Erijman EA.

Biophys J. 2012 Apr 4;102(7):1598-607. doi: 10.1016/j.bpj.2012.03.010. Epub 2012 Apr 3.

25.

Supramolecular non-amyloid intermediates in the early stages of α-synuclein aggregation.

Fauerbach JA, Yushchenko DA, Shahmoradian SH, Chiu W, Jovin TM, Jares-Erijman EA.

Biophys J. 2012 Mar 7;102(5):1127-36. doi: 10.1016/j.bpj.2012.01.051. Epub 2012 Mar 6.

26.

The mode of α-synuclein binding to membranes depends on lipid composition and lipid to protein ratio.

Shvadchak VV, Yushchenko DA, Pievo R, Jovin TM.

FEBS Lett. 2011 Nov 16;585(22):3513-9. doi: 10.1016/j.febslet.2011.10.006. Epub 2011 Oct 12.

27.

Confocal fluorescence anisotropy and FRAP imaging of α-synuclein amyloid aggregates in living cells.

Roberti MJ, Jovin TM, Jares-Erijman E.

PLoS One. 2011;6(8):e23338. doi: 10.1371/journal.pone.0023338. Epub 2011 Aug 8.

28.

Electron paramagnetic resonance spectroscopy measures the distance between the external β-strands of folded α-synuclein in amyloid fibrils.

Karyagina I, Becker S, Giller K, Riedel D, Jovin TM, Griesinger C, Bennati M.

Biophys J. 2011 Jul 6;101(1):L1-3. doi: 10.1016/j.bpj.2011.05.052.

29.

Photoswitchable water-soluble quantum dots: pcFRET based on amphiphilic photochromic polymer coating.

Díaz SA, Menéndez GO, Etchehon MH, Giordano L, Jovin TM, Jares-Erijman EA.

ACS Nano. 2011 Apr 26;5(4):2795-805. doi: 10.1021/nn103243c. Epub 2011 Mar 16.

PMID:
21375335
30.

FRET imaging by k(t)/k(f).

Roberti MJ, Giordano L, Jovin TM, Jares-Erijman EA.

Chemphyschem. 2011 Feb 25;12(3):563-6. doi: 10.1002/cphc.201000925. Epub 2011 Jan 27. No abstract available. Erratum in: Chemphyschem. 2011 Apr 18;12(6):1033.

PMID:
21344594
31.

Specificity and kinetics of alpha-synuclein binding to model membranes determined with fluorescent excited state intramolecular proton transfer (ESIPT) probe.

Shvadchak VV, Falomir-Lockhart LJ, Yushchenko DA, Jovin TM.

J Biol Chem. 2011 Apr 15;286(15):13023-32. doi: 10.1074/jbc.M110.204776. Epub 2011 Feb 17.

32.

Differential endocytosis and signaling dynamics of insulin receptor variants IR-A and IR-B.

Giudice J, Leskow FC, Arndt-Jovin DJ, Jovin TM, Jares-Erijman EA.

J Cell Sci. 2011 Mar 1;124(Pt 5):801-11. doi: 10.1242/jcs.076869. Epub 2011 Feb 8. Retraction in: J Cell Sci. 2012 Jun 1;125(Pt 11):2786.

33.

Minimizing light exposure with the programmable array microscope.

Caarls W, Rieger B, De Vries AH, Arndt-Jovin DJ, Jovin TM.

J Microsc. 2011 Jan;241(1):101-10. doi: 10.1111/j.1365-2818.2010.03413.x.

34.

Sensitivity analysis predicts that the ERK-pMEK interaction regulates ERK nuclear translocation.

Radhakrishnan K, Edwards JS, Lidke DS, Jovin TM, Wilson BS, Oliver JM.

IET Syst Biol. 2009 Sep;3(5):329-41. doi: 10.1049/iet-syb.2009.0010.

35.

Enzyme reaction in the pores of CaCO3 particles upon ultrasound disruption of attached substrate-filled liposomes.

Yashchenok AM, Delcea M, Videnova K, Jares-Erijman EA, Jovin TM, Konrad M, Möhwald H, Skirtach AG.

Angew Chem Int Ed Engl. 2010 Oct 25;49(44):8116-20. doi: 10.1002/anie.201003244. No abstract available.

PMID:
20859979
36.

Distribution of resting and ligand-bound ErbB1 and ErbB2 receptor tyrosine kinases in living cells using number and brightness analysis.

Nagy P, Claus J, Jovin TM, Arndt-Jovin DJ.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16524-9. doi: 10.1073/pnas.1002642107. Epub 2010 Sep 2.

37.

Targeted cellular delivery of quantum dots loaded on and in biotinylated liposomes.

Sigot V, Arndt-Jovin DJ, Jovin TM.

Bioconjug Chem. 2010 Aug 18;21(8):1465-72. doi: 10.1021/bc100054c.

PMID:
20715851
38.

Specific visualization of glioma cells in living low-grade tumor tissue.

Kantelhardt SR, Caarls W, de Vries AH, Hagen GM, Jovin TM, Schulz-Schaeffer W, Rohde V, Giese A, Arndt-Jovin DJ.

PLoS One. 2010 Jun 30;5(6):e11323. doi: 10.1371/journal.pone.0011323.

39.

Fluorescent ratiometric MFC probe sensitive to early stages of alpha-synuclein aggregation.

Yushchenko DA, Fauerbach JA, Thirunavukkuarasu S, Jares-Erijman EA, Jovin TM.

J Am Chem Soc. 2010 Jun 16;132(23):7860-1. doi: 10.1021/ja102838n.

PMID:
20491471
40.

ERK nuclear translocation is dimerization-independent but controlled by the rate of phosphorylation.

Lidke DS, Huang F, Post JN, Rieger B, Wilsbacher J, Thomas JL, Pouysségur J, Jovin TM, Lenormand P.

J Biol Chem. 2010 Jan 29;285(5):3092-102. doi: 10.1074/jbc.M109.064972. Epub 2009 Nov 17.

41.

A new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cells.

Galli S, Jahn O, Hitt R, Hesse D, Opitz L, Plessmann U, Urlaub H, Poderoso JJ, Jares-Erijman EA, Jovin TM.

PLoS One. 2009 Oct 22;4(10):e7541. doi: 10.1371/journal.pone.0007541.

42.

Characterization of coupled ground state and excited state equilibria by fluorescence spectral deconvolution.

Caarls W, Soledad Celej M, Demchenko AP, Jovin TM.

J Fluoresc. 2010 Jan;20(1):181-90. doi: 10.1007/s10895-009-0536-1. Epub 2009 Sep 23.

43.

Induction of terminal differentiation in melanoma cells on downregulation of beta-amyloid precursor protein.

Botelho MG, Wang X, Arndt-Jovin DJ, Becker D, Jovin TM.

J Invest Dermatol. 2010 May;130(5):1400-10. doi: 10.1038/jid.2009.296. Epub 2009 Sep 17.

44.

A triple-emission fluorescent probe reveals distinctive amyloid fibrillar polymorphism of wild-type alpha-synuclein and its familial Parkinson's disease mutants.

Celej MS, Caarls W, Demchenko AP, Jovin TM.

Biochemistry. 2009 Aug 11;48(31):7465-72. doi: 10.1021/bi9003843.

PMID:
19586054
45.

Introduction to the special section on colloidal quantum dots for biomedical applications.

Osiński M, Jovin TM, Yamamoto K.

IEEE Trans Nanobioscience. 2009 Mar;8(1):1-3. doi: 10.1109/TNB.2009.2021215. No abstract available.

PMID:
19556190
46.

Quantum dots as ultrasensitive nanoactuators and sensors of amyloid aggregation in live cells.

Roberti MJ, Morgan M, Menéndez G, Pietrasanta LI, Jovin TM, Jares-Erijman EA.

J Am Chem Soc. 2009 Jun 17;131(23):8102-7. doi: 10.1021/ja900225w.

PMID:
19462994
47.

Dynamic conformational changes in the FERM domain of FAK are involved in focal-adhesion behavior during cell spreading and motility.

Papusheva E, Mello de Queiroz F, Dalous J, Han Y, Esposito A, Jares-Erijmanxa EA, Jovin TM, Bunt G.

J Cell Sci. 2009 Mar 1;122(Pt 5):656-66. doi: 10.1242/jcs.028738. Epub 2009 Feb 10.

48.

Fluorescence recovery after photobleaching and photoconversion in multiple arbitrary regions of interest using a programmable array microscope.

Hagen GM, Caarls W, Lidke KA, De Vries AH, Fritsch C, Barisas BG, Arndt-Jovin DJ, Jovin TM.

Microsc Res Tech. 2009 Jun;72(6):431-40. doi: 10.1002/jemt.20686.

49.

7-Aminoactinomycin binding to DNA sequences lacking GpC sites: a thermodynamic and kinetic study.

Biver T, Venturini M, Jares-Erijman EA, Jovin TM, Secco F.

Biochemistry. 2009 Jan 13;48(1):173-9. doi: 10.1021/bi801671c.

PMID:
19072038
50.

satFRET: estimation of Förster resonance energy transfer by acceptor saturation.

Beutler M, Makrogianneli K, Vermeij RJ, Keppler M, Ng T, Jovin TM, Heintzmann R.

Eur Biophys J. 2008 Nov;38(1):69-82. doi: 10.1007/s00249-008-0361-5. Epub 2008 Sep 4.

PMID:
18769914

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