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Items: 1 to 50 of 353

1.

Multiplexed monitoring of a novel autoantibody diagnostic signature of colorectal cancer using HaloTag technology-based electrochemical immunosensing platform.

Garranzo-Asensio M, Guzmán-Aránguez A, Povedano E, Ruiz-Valdepeñas Montiel V, Poves C, Fernandez-Aceñero MJ, Montero-Calle A, Solís-Fernández G, Fernandez-Diez S, Camps J, Arenas M, Rodríguez-Tomàs E, Joven J, Sanchez-Martinez M, Rodriguez N, Dominguez G, Yáñez-Sedeño P, Pingarrón JM, Campuzano S, Barderas R.

Theranostics. 2020 Feb 10;10(7):3022-3034. doi: 10.7150/thno.42507. eCollection 2020.

2.

Alterations in plasma concentrations of energy-balance-related metabolites in patients with lung, or head & neck, cancers: Effects of radiotherapy.

Rodríguez-Tomàs E, Arguís M, Arenas M, Fernández-Arroyo S, Murcia M, Sabater S, Torres L, Baiges-Gayà G, Hernández-Aguilera A, Camps J, Joven J.

J Proteomics. 2020 Feb 20;213:103605. doi: 10.1016/j.jprot.2019.103605. Epub 2019 Dec 11.

PMID:
31841666
3.

Neoadjuvant Metformin Added to Systemic Therapy Decreases the Proliferative Capacity of Residual Breast Cancer.

Lopez-Bonet E, Buxó M, Cuyàs E, Pernas S, Dorca J, Álvarez I, Martínez S, Pérez-Garcia JM, Batista-López N, Rodríguez-Sánchez CA, Amillano K, Domínguez S, Luque M, Morilla I, Stradella A, Viñas G, Cortés J, Oliveras G, Meléndez C, Castillo L, Verdura S, Brunet J, Joven J, Garcia M, Saidani S, Martin-Castillo B, Menendez JA.

J Clin Med. 2019 Dec 11;8(12). pii: E2180. doi: 10.3390/jcm8122180.

4.

Plasma metabolic alterations in patients with severe obesity and non-alcoholic steatohepatitis.

Cabré N, Luciano-Mateo F, Baiges-Gayà G, Fernández-Arroyo S, Rodríguez-Tomàs E, Hernández-Aguilera A, París M, Sabench F, Del Castillo D, López-Miranda J, Menéndez JA, Camps J, Joven J.

Aliment Pharmacol Ther. 2020 Feb;51(3):374-387. doi: 10.1111/apt.15606. Epub 2019 Dec 11.

PMID:
31825539
5.

Chemokine (C-C motif) ligand 2 and coronary artery disease: Tissue expression of functional and atypical receptors.

Hernández-Aguilera A, Fibla M, Cabré N, Luciano-Mateo F, Camps J, Fernández-Arroyo S, Martín-Paredero V, Menendez JA, Sirvent JJ, Joven J.

Cytokine. 2020 Feb;126:154923. doi: 10.1016/j.cyto.2019.154923. Epub 2019 Nov 15.

PMID:
31739217
6.

Effects of radiotherapy on plasma energy metabolites in patients with breast cancer who received neoadjuvant chemotherapy.

Arenas M, Fernández-Arroyo S, Rodríguez-Tomàs E, Sabater S, Murria Y, Gascón M, Amillano K, Melé M, Camps J, Joven J.

Clin Transl Oncol. 2019 Nov 2. doi: 10.1007/s12094-019-02232-6. [Epub ahead of print]

PMID:
31679126
7.

In silico clinical trials for anti-aging therapies.

Menendez JA, Cuyàs E, Folguera-Blasco N, Verdura S, Martin-Castillo B, Joven J, Alarcón T.

Aging (Albany NY). 2019 Aug 24;11(16):6591-6601. doi: 10.18632/aging.102180. Epub 2019 Aug 24.

8.

Serum Paraoxonase-1-Related Variables and Lipoprotein Profile in Patients with Lung or Head and Neck Cancer: Effect of Radiotherapy.

Rodríguez-Tomàs E, Murcia M, Arenas M, Arguís M, Gil M, Amigó N, Correig X, Torres L, Sabater S, Baiges-Gayà G, Cabré N, Luciano-Mateo F, Hernández-Aguilera A, Fort-Gallifa I, Camps J, Joven J.

Antioxidants (Basel). 2019 Jul 10;8(7). pii: E213. doi: 10.3390/antiox8070213.

9.

Laparoscopic sleeve gastrectomy reverses non-alcoholic fatty liver disease modulating oxidative stress and inflammation.

Cabré N, Luciano-Mateo F, Fernández-Arroyo S, Baiges-Gayà G, Hernández-Aguilera A, Fibla M, Fernández-Julià R, París M, Sabench F, Castillo DD, Menéndez JA, Camps J, Joven J.

Metabolism. 2019 Oct;99:81-89. doi: 10.1016/j.metabol.2019.07.002. Epub 2019 Jul 4.

PMID:
31279739
10.

Revisiting silibinin as a novobiocin-like Hsp90 C-terminal inhibitor: Computational modeling and experimental validation.

Cuyàs E, Verdura S, Micol V, Joven J, Bosch-Barrera J, Encinar JA, Menendez JA.

Food Chem Toxicol. 2019 Oct;132:110645. doi: 10.1016/j.fct.2019.110645. Epub 2019 Jun 26.

PMID:
31254591
11.

Correction: Palmitate Conditions Macrophages for Enhanced Responses toward Inflammatory Stimuli via JNK Activation.

Riera-Borrull M, Cuevas VD, Alonso B, Vega MA, Joven J, Izquierdo E, Corbí ÁL.

J Immunol. 2019 Jul 15;203(2):580. doi: 10.4049/jimmunol.1900602. Epub 2019 Jun 7. No abstract available.

PMID:
31175161
12.

Computational de-orphanization of the olive oil biophenol oleacein: Discovery of new metabolic and epigenetic targets.

Cuyàs E, Castillo D, Llorach-Parés L, Lozano-Sánchez J, Verdura S, Nonell-Canals A, Brunet J, Bosch-Barrera J, Joven J, Valdés R, Sanchez-Martinez M, Segura-Carretero A, Menendez JA.

Food Chem Toxicol. 2019 Sep;131:110529. doi: 10.1016/j.fct.2019.05.037. Epub 2019 May 29.

PMID:
31150784
13.

Effect of Vitamin D3 on the Postprandial Lipid Profile in Obese Patients: A Non-Targeted Lipidomics Study.

Fernández-Arroyo S, Hernández-Aguilera A, de Vries MA, Burggraaf B, van der Zwan E, Pouw N, Joven J, Cabezas MC.

Nutrients. 2019 May 27;11(5). pii: E1194. doi: 10.3390/nu11051194.

14.

Metformin induces a fasting- and antifolate-mimicking modification of systemic host metabolism in breast cancer patients.

Cuyàs E, Fernández-Arroyo S, Buxó M, Pernas S, Dorca J, Álvarez I, Martínez S, Pérez-Garcia JM, Batista-López N, Rodríguez-Sánchez CA, Amillano K, Domínguez S, Luque M, Morilla I, Stradella A, Viñas G, Cortés J, Verdura S, Brunet J, López-Bonet E, Garcia M, Saidani S, Joven J, Martin-Castillo B, Menendez JA.

Aging (Albany NY). 2019 May 9;11(9):2874-2888. doi: 10.18632/aging.101960.

15.

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease.

Hernández-Alvarez MI, Sebastián D, Vives S, Ivanova S, Bartoccioni P, Kakimoto P, Plana N, Veiga SR, Hernández V, Vasconcelos N, Peddinti G, Adrover A, Jové M, Pamplona R, Gordaliza-Alaguero I, Calvo E, Cabré N, Castro R, Kuzmanic A, Boutant M, Sala D, Hyotylainen T, Orešič M, Fort J, Errasti-Murugarren E, Rodrígues CMP, Orozco M, Joven J, Cantó C, Palacin M, Fernández-Veledo S, Vendrell J, Zorzano A.

Cell. 2019 May 2;177(4):881-895.e17. doi: 10.1016/j.cell.2019.04.010.

PMID:
31051106
16.

Stratification of cancer and diabetes based on circulating levels of formate and glucose.

Pietzke M, Arroyo SF, Sumpton D, Mackay GM, Martin-Castillo B, Camps J, Joven J, Menendez JA, Vazquez A; METTEN study group.

Cancer Metab. 2019 Apr 24;7:3. doi: 10.1186/s40170-019-0195-x. eCollection 2019.

17.

The C Allele of ATM rs11212617 Associates With Higher Pathological Complete Remission Rate in Breast Cancer Patients Treated With Neoadjuvant Metformin.

Cuyàs E, Buxó M, Ferri Iglesias MJ, Verdura S, Pernas S, Dorca J, Álvarez I, Martínez S, Pérez-Garcia JM, Batista-López N, Rodríguez-Sánchez CA, Amillano K, Domínguez S, Luque M, Morilla I, Stradella A, Viñas G, Cortés J, Joven J, Brunet J, López-Bonet E, Garcia M, Saidani S, Queralt Moles X, Martin-Castillo B, Menendez JA.

Front Oncol. 2019 Mar 28;9:193. doi: 10.3389/fonc.2019.00193. eCollection 2019.

18.

Influence of Surgical Procedures on Serum Paraoxonase-1-Related Variables and Markers of Inflammation in Hospitalized Patients.

Iftimie S, Escribano A, Díez-Sans A, Albiciuc I, Hernández-Aguilera A, Fort-Gallifa I, López-Azcona AF, Camps J, Joven J, Castro A.

J Invest Surg. 2019 Apr 4:1-9. doi: 10.1080/08941939.2019.1597223. [Epub ahead of print]

PMID:
30947571
19.

Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers.

Pérez-Sánchez A, Cuyàs E, Ruiz-Torres V, Agulló-Chazarra L, Verdura S, González-Álvarez I, Bermejo M, Joven J, Micol V, Bosch-Barrera J, Menendez JA.

Int J Mol Sci. 2019 Mar 31;20(7). pii: E1606. doi: 10.3390/ijms20071606.

20.

Chemokine (C-C motif) ligand 2 gene ablation protects low-density lipoprotein and paraoxonase-1 double deficient mice from liver injury, oxidative stress and inflammation.

Luciano-Mateo F, Cabré N, Fernández-Arroyo S, Baiges-Gaya G, Hernández-Aguilera A, Rodríguez-Tomàs E, Mercado-Gómez M, Menendez JA, Camps J, Joven J.

Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1555-1566. doi: 10.1016/j.bbadis.2019.03.006. Epub 2019 Mar 21.

PMID:
30905786
21.

Different behavior of polyphenols in energy metabolism of lipopolysaccharide-stimulated cells.

de la Luz Cádiz-Gurrea M, Micol V, Joven J, Segura-Carretero A, Fernández-Arroyo S.

Food Res Int. 2019 Apr;118:96-100. doi: 10.1016/j.foodres.2018.02.027. Epub 2018 Feb 13.

PMID:
30898358
22.

Treating atherosclerosis: targeting risk factors should not be the only option.

Fibla M, Hernández-Aguilera A, Camps J, Menendez JA, Joven J.

Ann Transl Med. 2018 Nov;6(Suppl 1):S34. doi: 10.21037/atm.2018.09.40. No abstract available.

23.

Versatile Electroanalytical Bioplatforms for Simultaneous Determination of Cancer-Related DNA 5-Methyl- and 5-Hydroxymethyl-Cytosines at Global and Gene-Specific Levels in Human Serum and Tissues.

Povedano E, Montiel VR, Valverde A, Navarro-Villoslada F, Yáñez-Sedeño P, Pedrero M, Montero-Calle A, Barderas R, Peláez-García A, Mendiola M, Hardisson D, Feliú J, Camps J, Rodríguez-Tomàs E, Joven J, Arenas M, Campuzano S, Pingarrón JM.

ACS Sens. 2019 Jan 25;4(1):227-234. doi: 10.1021/acssensors.8b01339. Epub 2018 Dec 14.

PMID:
30499292
24.

A phase 2 trial of neoadjuvant metformin in combination with trastuzumab and chemotherapy in women with early HER2-positive breast cancer: the METTEN study.

Martin-Castillo B, Pernas S, Dorca J, Álvarez I, Martínez S, Pérez-Garcia JM, Batista-López N, Rodríguez-Sánchez CA, Amillano K, Domínguez S, Luque M, Stradella A, Morilla I, Viñas G, Cortés J, Cuyàs E, Verdura S, Fernández-Ochoa Á, Fernández-Arroyo S, Segura-Carretero A, Joven J, Pérez E, Bosch N, Garcia M, López-Bonet E, Saidani S, Buxó M, Menendez JA.

Oncotarget. 2018 Nov 2;9(86):35687-35704. doi: 10.18632/oncotarget.26286. eCollection 2018 Nov 2.

25.

Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation.

Cuyàs E, Verdura S, Llorach-Parés L, Fernández-Arroyo S, Joven J, Martin-Castillo B, Bosch-Barrera J, Brunet J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA.

Front Endocrinol (Lausanne). 2018 Nov 6;9:657. doi: 10.3389/fendo.2018.00657. eCollection 2018.

26.

Metabolite normalization with local radiotherapy following breast tumor resection.

Arenas M, Rodríguez E, García-Heredia A, Fernández-Arroyo S, Sabater S, Robaina R, Gascón M, Rodríguez-Pla M, Cabré N, Luciano-Mateo F, Hernández-Aguilera A, Fort-Gallifa I, Camps J, Joven J.

PLoS One. 2018 Nov 16;13(11):e0207474. doi: 10.1371/journal.pone.0207474. eCollection 2018.

27.

An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors.

Verdura S, Cuyàs E, Lozano-Sánchez J, Bastidas-Velez C, Llorach-Parés L, Fernández-Arroyo S, Hernández-Aguilera A, Joven J, Nonell-Canals A, Bosch-Barrera J, Martin-Castillo B, Vellon L, Sanchez-Martinez M, Segura-Carretero A, Menendez JA.

Carcinogenesis. 2019 Mar 12;40(1):27-40. doi: 10.1093/carcin/bgy159.

PMID:
30428017
28.

Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease.

Hernández-Aguilera A, Fernández-Arroyo S, Cabre N, Luciano-Mateo F, Baiges-Gaya G, Fibla M, Martín-Paredero V, Menendez JA, Camps J, Joven J.

Mediators Inflamm. 2018 Sep 20;2018:2760272. doi: 10.1155/2018/2760272. eCollection 2018.

29.

Trace element concentrations in breast cancer patients.

Cabré N, Luciano-Mateo F, Arenas M, Nadal M, Baiges-Gaya G, Hernández-Aguilera A, Fort-Gallifa I, Rodríguez E, Riu F, Camps J, Joven J, Domingo JL.

Breast. 2018 Dec;42:142-149. doi: 10.1016/j.breast.2018.09.005. Epub 2018 Oct 1.

PMID:
30296647
30.

Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.

Garrido P, Rovira C, Cueto P, Fort-Gallifa I, Hernández-Aguilera A, Cabré N, Luciano-Mateo F, García-Heredia A, Camps J, Joven J, Garcia E, Vallverdú I.

Clin Biochem. 2018 Nov;61:1-6. doi: 10.1016/j.clinbiochem.2018.08.010. Epub 2018 Aug 27.

PMID:
30165052
31.

Paraoxonase-1 activity in patients with cancer: A systematic review and meta-analysis.

Arenas M, Rodríguez E, Sahebkar A, Sabater S, Rizo D, Pallisé O, Hernández M, Riu F, Camps J, Joven J.

Crit Rev Oncol Hematol. 2018 Jul;127:6-14. doi: 10.1016/j.critrevonc.2018.04.005. Epub 2018 Apr 26. Review.

PMID:
29891113
32.

Serum concentrations of trace elements and their relationships with paraoxonase-1 in morbidly obese women.

Luciano-Mateo F, Cabré N, Nadal M, García-Heredia A, Baiges-Gaya G, Hernández-Aguilera A, Camps J, Joven J, Domingo JL.

J Trace Elem Med Biol. 2018 Jul;48:8-15. doi: 10.1016/j.jtemb.2018.02.023. Epub 2018 Mar 1.

PMID:
29773198
33.

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX.

Cuyàs E, Verdura S, Llorach-Pares L, Fernández-Arroyo S, Luciano-Mateo F, Cabré N, Stursa J, Werner L, Martin-Castillo B, Viollet B, Neuzil J, Joven J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA.

Aging Cell. 2018 Aug;17(4):e12772. doi: 10.1111/acel.12772. Epub 2018 May 8.

34.

Serum Paraoxonase-1 Concentration as a Potential Predictor of Urinary Bladder Cancer Recurrence. A Five Year Follow-Up Study.

Iftimie S, García-Heredia A, Pujol-Bosch F, Pont-Salvadó A, López-Azcona AF, Hernández-Aguilera A, Cabré N, Luciano-Mateo F, Fort-Gallifa I, Castro A, Camps J, Joven J.

Arch Med Res. 2018 Feb;49(2):119-122. doi: 10.1016/j.arcmed.2018.04.011. Epub 2018 Apr 24.

PMID:
29699809
35.

Silibinin is a direct inhibitor of STAT3.

Verdura S, Cuyàs E, Llorach-Parés L, Pérez-Sánchez A, Micol V, Nonell-Canals A, Joven J, Valiente M, Sánchez-Martínez M, Bosch-Barrera J, Menendez JA.

Food Chem Toxicol. 2018 Jun;116(Pt B):161-172. doi: 10.1016/j.fct.2018.04.028. Epub 2018 Apr 14.

PMID:
29660364
36.

Assessment of extracellular matrix-related biomarkers in patients with lower extremity artery disease.

Hernández-Aguilera A, Nielsen SH, Bonache C, Fernández-Arroyo S, Martín-Paredero V, Fibla M, Karsdal MA, Genovese F, Menendez JA, Camps J, Joven J.

J Vasc Surg. 2018 Oct;68(4):1135-1142.e6. doi: 10.1016/j.jvs.2017.12.071. Epub 2018 Mar 31.

PMID:
29615349
37.

Trace Elements and Paraoxonase-1 Activity in Lower Extremity Artery Disease.

Rovira J, Hernández-Aguilera A, Luciano-Mateo F, Cabré N, Baiges-Gaya G, Nadal M, Martín-Paredero V, Camps J, Joven J, Domingo JL.

Biol Trace Elem Res. 2018 Nov;186(1):74-84. doi: 10.1007/s12011-018-1298-x. Epub 2018 Mar 10.

PMID:
29525848
38.

Plant-Derived Polyphenols in Human Health: Biological Activity, Metabolites and Putative Molecular Targets.

Olivares-Vicente M, Barrajon-Catalan E, Herranz-Lopez M, Segura-Carretero A, Joven J, Encinar JA, Micol V.

Curr Drug Metab. 2018;19(4):351-369. doi: 10.2174/1389200219666180220095236. Review.

PMID:
29468962
39.

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells.

Corominas-Faja B, Cuyàs E, Lozano-Sánchez J, Cufí S, Verdura S, Fernández-Arroyo S, Borrás-Linares I, Martin-Castillo B, Martin ÁG, Lupu R, Nonell-Canals A, Sanchez-Martinez M, Micol V, Joven J, Segura-Carretero A, Menendez JA.

Carcinogenesis. 2018 Apr 5;39(4):601-613. doi: 10.1093/carcin/bgy023.

40.

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity.

Cuyàs E, Verdura S, Fernández-Arroyo S, Bosch-Barrera J, Martin-Castillo B, Joven J, Menendez JA.

Oncotarget. 2017 Oct 15;8(59):99223-99236. doi: 10.18632/oncotarget.21834. eCollection 2017 Nov 21.

41.

Effect of radiotherapy on activity and concentration of serum paraoxonase-1 in breast cancer patients.

Arenas M, García-Heredia A, Cabré N, Luciano-Mateo F, Hernández-Aguilera A, Sabater S, Bonet M, Gascón M, Fernández-Arroyo S, Fort-Gallifa I, Camps J, Joven J.

PLoS One. 2017 Nov 27;12(11):e0188633. doi: 10.1371/journal.pone.0188633. eCollection 2017.

42.

Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.

Riera-Borrull M, García-Heredia A, Fernández-Arroyo S, Hernández-Aguilera A, Cabré N, Cuyàs E, Luciano-Mateo F, Camps J, Menendez JA, Joven J.

Int J Mol Sci. 2017 Oct 28;18(11). pii: E2263. doi: 10.3390/ijms18112263.

43.

An Electrochemical Enzyme Biosensor for 3-Hydroxybutyrate Detection Using Screen-Printed Electrodes Modified by Reduced Graphene Oxide and Thionine.

Martínez-García G, Pérez-Julián E, Agüí L, Cabré N, Joven J, Yáñez-Sedeño P, Pingarrón JM.

Biosensors (Basel). 2017 Nov 11;7(4). pii: E50. doi: 10.3390/bios7040050.

44.

Palmitate Conditions Macrophages for Enhanced Responses toward Inflammatory Stimuli via JNK Activation.

Riera-Borrull M, Cuevas VD, Alonso B, Vega MA, Joven J, Izquierdo E, Corbí ÁL.

J Immunol. 2017 Dec 1;199(11):3858-3869. doi: 10.4049/jimmunol.1700845. Epub 2017 Oct 23. Erratum in: J Immunol. 2019 Jul 15;203(2):580.

45.

Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism.

Cuyàs E, Fernández-Arroyo S, Verdura S, García RÁ, Stursa J, Werner L, Blanco-González E, Montes-Bayón M, Joven J, Viollet B, Neuzil J, Menendez JA.

Oncogene. 2018 Feb 15;37(7):963-970. doi: 10.1038/onc.2017.367. Epub 2017 Oct 23.

PMID:
29059169
46.

Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity.

Herranz-López M, Olivares-Vicente M, Encinar JA, Barrajón-Catalán E, Segura-Carretero A, Joven J, Micol V.

Nutrients. 2017 Aug 20;9(8). pii: E907. doi: 10.3390/nu9080907. Review.

47.

Galectin-3 in Peripheral Artery Disease. Relationships with Markers of Oxidative Stress and Inflammation.

Fort-Gallifa I, Hernández-Aguilera A, García-Heredia A, Cabré N, Luciano-Mateo F, Simó JM, Martín-Paredero V, Camps J, Joven J.

Int J Mol Sci. 2017 May 4;18(5). pii: E973. doi: 10.3390/ijms18050973.

48.

Paraoxonases and infectious diseases.

Camps J, Iftimie S, García-Heredia A, Castro A, Joven J.

Clin Biochem. 2017 Sep;50(13-14):804-811. doi: 10.1016/j.clinbiochem.2017.04.016. Epub 2017 Apr 19. Review.

PMID:
28433610
49.

Cocoa and Grape Seed Byproducts as a Source of Antioxidant and Anti-Inflammatory Proanthocyanidins.

Cádiz-Gurrea ML, Borrás-Linares I, Lozano-Sánchez J, Joven J, Fernández-Arroyo S, Segura-Carretero A.

Int J Mol Sci. 2017 Feb 10;18(2). pii: E376. doi: 10.3390/ijms18020376.

50.

Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users.

Luciano-Mateo F, Hernández-Aguilera A, Cabre N, Camps J, Fernández-Arroyo S, Lopez-Miranda J, Menendez JA, Joven J.

Nutrients. 2017 Feb 10;9(2). pii: E121. doi: 10.3390/nu9020121. Review.

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