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Items: 1 to 50 of 332

1.

Treating atherosclerosis: targeting risk factors should not be the only option.

Fibla M, Hernández-Aguilera A, Camps J, Menendez JA, Joven J.

Ann Transl Med. 2018 Nov;6(Suppl 1):S34. doi: 10.21037/atm.2018.09.40. No abstract available.

2.

Versatile Electroanalytical Bioplatforms for Simultaneous Determination of Cancer-Related DNA 5-Methyl- and 5-Hydroxymethyl-Cytosines at Global and Gene-Specific Levels in Human Serum and Tissues.

Povedano E, Montiel VR, Valverde A, Navarro-Villoslada F, Yáñez-Sedeño P, Pedrero M, Montero-Calle A, Barderas R, Peláez-García A, Mendiola M, Hardisson D, Feliú J, Camps J, Rodríguez-Tomàs E, Joven J, Arenas M, Campuzano S, Pingarrón JM.

ACS Sens. 2019 Jan 25;4(1):227-234. doi: 10.1021/acssensors.8b01339. Epub 2018 Dec 14.

PMID:
30499292
3.

A phase 2 trial of neoadjuvant metformin in combination with trastuzumab and chemotherapy in women with early HER2-positive breast cancer: the METTEN study.

Martin-Castillo B, Pernas S, Dorca J, Álvarez I, Martínez S, Pérez-Garcia JM, Batista-López N, Rodríguez-Sánchez CA, Amillano K, Domínguez S, Luque M, Stradella A, Morilla I, Viñas G, Cortés J, Cuyàs E, Verdura S, Fernández-Ochoa Á, Fernández-Arroyo S, Segura-Carretero A, Joven J, Pérez E, Bosch N, Garcia M, López-Bonet E, Saidani S, Buxó M, Menendez JA.

Oncotarget. 2018 Nov 2;9(86):35687-35704. doi: 10.18632/oncotarget.26286. eCollection 2018 Nov 2.

4.

Metformin Is a Direct SIRT1-Activating Compound: Computational Modeling and Experimental Validation.

Cuyàs E, Verdura S, Llorach-Parés L, Fernández-Arroyo S, Joven J, Martin-Castillo B, Bosch-Barrera J, Brunet J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA.

Front Endocrinol (Lausanne). 2018 Nov 6;9:657. doi: 10.3389/fendo.2018.00657. eCollection 2018.

5.

Metabolite normalization with local radiotherapy following breast tumor resection.

Arenas M, Rodríguez E, García-Heredia A, Fernández-Arroyo S, Sabater S, Robaina R, Gascón M, Rodríguez-Pla M, Cabré N, Luciano-Mateo F, Hernández-Aguilera A, Fort-Gallifa I, Camps J, Joven J.

PLoS One. 2018 Nov 16;13(11):e0207474. doi: 10.1371/journal.pone.0207474. eCollection 2018.

6.

An olive oil phenolic is a new chemotype of mutant isocitrate dehydrogenase 1 (IDH1) inhibitors.

Verdura S, Cuyàs E, Lozano-Sánchez J, Bastidas-Velez C, Llorach-Parés L, Fernández-Arroyo S, Hernández-Aguilera A, Joven J, Nonell-Canals A, Bosch-Barrera J, Martin-Castillo B, Vellon L, Sanchez-Martinez M, Segura-Carretero A, Menendez JA.

Carcinogenesis. 2018 Nov 14. doi: 10.1093/carcin/bgy159. [Epub ahead of print]

PMID:
30428017
7.

Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease.

Hernández-Aguilera A, Fernández-Arroyo S, Cabre N, Luciano-Mateo F, Baiges-Gaya G, Fibla M, Martín-Paredero V, Menendez JA, Camps J, Joven J.

Mediators Inflamm. 2018 Sep 20;2018:2760272. doi: 10.1155/2018/2760272. eCollection 2018.

8.

Trace element concentrations in breast cancer patients.

Cabré N, Luciano-Mateo F, Arenas M, Nadal M, Baiges-Gaya G, Hernández-Aguilera A, Fort-Gallifa I, Rodríguez E, Riu F, Camps J, Joven J, Domingo JL.

Breast. 2018 Dec;42:142-149. doi: 10.1016/j.breast.2018.09.005. Epub 2018 Oct 1.

PMID:
30296647
9.

Effect of continuous renal-replacement therapy on paraoxonase-1-related variables in patients with acute renal failure caused by septic shock.

Garrido P, Rovira C, Cueto P, Fort-Gallifa I, Hernández-Aguilera A, Cabré N, Luciano-Mateo F, García-Heredia A, Camps J, Joven J, Garcia E, Vallverdú I.

Clin Biochem. 2018 Nov;61:1-6. doi: 10.1016/j.clinbiochem.2018.08.010. Epub 2018 Aug 27.

PMID:
30165052
10.

Paraoxonase-1 activity in patients with cancer: A systematic review and meta-analysis.

Arenas M, Rodríguez E, Sahebkar A, Sabater S, Rizo D, Pallisé O, Hernández M, Riu F, Camps J, Joven J.

Crit Rev Oncol Hematol. 2018 Jul;127:6-14. doi: 10.1016/j.critrevonc.2018.04.005. Epub 2018 Apr 26. Review.

PMID:
29891113
11.

Serum concentrations of trace elements and their relationships with paraoxonase-1 in morbidly obese women.

Luciano-Mateo F, Cabré N, Nadal M, García-Heredia A, Baiges-Gaya G, Hernández-Aguilera A, Camps J, Joven J, Domingo JL.

J Trace Elem Med Biol. 2018 Jul;48:8-15. doi: 10.1016/j.jtemb.2018.02.023. Epub 2018 Mar 1.

PMID:
29773198
12.

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX.

Cuyàs E, Verdura S, Llorach-Pares L, Fernández-Arroyo S, Luciano-Mateo F, Cabré N, Stursa J, Werner L, Martin-Castillo B, Viollet B, Neuzil J, Joven J, Nonell-Canals A, Sanchez-Martinez M, Menendez JA.

Aging Cell. 2018 May 8:e12772. doi: 10.1111/acel.12772. [Epub ahead of print]

13.

Serum Paraoxonase-1 Concentration as a Potential Predictor of Urinary Bladder Cancer Recurrence. A Five Year Follow-Up Study.

Iftimie S, García-Heredia A, Pujol-Bosch F, Pont-Salvadó A, López-Azcona AF, Hernández-Aguilera A, Cabré N, Luciano-Mateo F, Fort-Gallifa I, Castro A, Camps J, Joven J.

Arch Med Res. 2018 Feb;49(2):119-122. doi: 10.1016/j.arcmed.2018.04.011. Epub 2018 Apr 24.

PMID:
29699809
14.

Silibinin is a direct inhibitor of STAT3.

Verdura S, Cuyàs E, Llorach-Parés L, Pérez-Sánchez A, Micol V, Nonell-Canals A, Joven J, Valiente M, Sánchez-Martínez M, Bosch-Barrera J, Menendez JA.

Food Chem Toxicol. 2018 Jun;116(Pt B):161-172. doi: 10.1016/j.fct.2018.04.028. Epub 2018 Apr 14.

PMID:
29660364
15.

Assessment of extracellular matrix-related biomarkers in patients with lower extremity artery disease.

Hernández-Aguilera A, Nielsen SH, Bonache C, Fernández-Arroyo S, Martín-Paredero V, Fibla M, Karsdal MA, Genovese F, Menendez JA, Camps J, Joven J.

J Vasc Surg. 2018 Oct;68(4):1135-1142.e6. doi: 10.1016/j.jvs.2017.12.071. Epub 2018 Mar 31.

PMID:
29615349
16.

Trace Elements and Paraoxonase-1 Activity in Lower Extremity Artery Disease.

Rovira J, Hernández-Aguilera A, Luciano-Mateo F, Cabré N, Baiges-Gaya G, Nadal M, Martín-Paredero V, Camps J, Joven J, Domingo JL.

Biol Trace Elem Res. 2018 Nov;186(1):74-84. doi: 10.1007/s12011-018-1298-x. Epub 2018 Mar 10.

PMID:
29525848
17.

Plant-Derived Polyphenols in Human Health: Biological Activity, Metabolites and Putative Molecular Targets.

Olivares-Vicente M, Barrajon-Catalan E, Herranz-Lopez M, Segura-Carretero A, Joven J, Encinar JA, Micol V.

Curr Drug Metab. 2018;19(4):351-369. doi: 10.2174/1389200219666180220095236. Review.

PMID:
29468962
18.

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells.

Corominas-Faja B, Cuyàs E, Lozano-Sánchez J, Cufí S, Verdura S, Fernández-Arroyo S, Borrás-Linares I, Martin-Castillo B, Martin ÁG, Lupu R, Nonell-Canals A, Sanchez-Martinez M, Micol V, Joven J, Segura-Carretero A, Menendez JA.

Carcinogenesis. 2018 Apr 5;39(4):601-613. doi: 10.1093/carcin/bgy023.

19.

Metabolomic mapping of cancer stem cells for reducing and exploiting tumor heterogeneity.

Cuyàs E, Verdura S, Fernández-Arroyo S, Bosch-Barrera J, Martin-Castillo B, Joven J, Menendez JA.

Oncotarget. 2017 Oct 15;8(59):99223-99236. doi: 10.18632/oncotarget.21834. eCollection 2017 Nov 21.

20.

Effect of radiotherapy on activity and concentration of serum paraoxonase-1 in breast cancer patients.

Arenas M, García-Heredia A, Cabré N, Luciano-Mateo F, Hernández-Aguilera A, Sabater S, Bonet M, Gascón M, Fernández-Arroyo S, Fort-Gallifa I, Camps J, Joven J.

PLoS One. 2017 Nov 27;12(11):e0188633. doi: 10.1371/journal.pone.0188633. eCollection 2017.

21.

Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.

Riera-Borrull M, García-Heredia A, Fernández-Arroyo S, Hernández-Aguilera A, Cabré N, Cuyàs E, Luciano-Mateo F, Camps J, Menendez JA, Joven J.

Int J Mol Sci. 2017 Oct 28;18(11). pii: E2263. doi: 10.3390/ijms18112263.

22.

An Electrochemical Enzyme Biosensor for 3-Hydroxybutyrate Detection Using Screen-Printed Electrodes Modified by Reduced Graphene Oxide and Thionine.

Martínez-García G, Pérez-Julián E, Agüí L, Cabré N, Joven J, Yáñez-Sedeño P, Pingarrón JM.

Biosensors (Basel). 2017 Nov 11;7(4). pii: E50. doi: 10.3390/bios7040050.

23.

Palmitate Conditions Macrophages for Enhanced Responses toward Inflammatory Stimuli via JNK Activation.

Riera-Borrull M, Cuevas VD, Alonso B, Vega MA, Joven J, Izquierdo E, Corbí ÁL.

J Immunol. 2017 Dec 1;199(11):3858-3869. doi: 10.4049/jimmunol.1700845. Epub 2017 Oct 23.

24.

Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism.

Cuyàs E, Fernández-Arroyo S, Verdura S, García RÁ, Stursa J, Werner L, Blanco-González E, Montes-Bayón M, Joven J, Viollet B, Neuzil J, Menendez JA.

Oncogene. 2018 Feb 15;37(7):963-970. doi: 10.1038/onc.2017.367. Epub 2017 Oct 23.

PMID:
29059169
25.

Multi-Targeted Molecular Effects of Hibiscus sabdariffa Polyphenols: An Opportunity for a Global Approach to Obesity.

Herranz-López M, Olivares-Vicente M, Encinar JA, Barrajón-Catalán E, Segura-Carretero A, Joven J, Micol V.

Nutrients. 2017 Aug 20;9(8). pii: E907. doi: 10.3390/nu9080907. Review.

26.

Galectin-3 in Peripheral Artery Disease. Relationships with Markers of Oxidative Stress and Inflammation.

Fort-Gallifa I, Hernández-Aguilera A, García-Heredia A, Cabré N, Luciano-Mateo F, Simó JM, Martín-Paredero V, Camps J, Joven J.

Int J Mol Sci. 2017 May 4;18(5). pii: E973. doi: 10.3390/ijms18050973.

27.

Paraoxonases and infectious diseases.

Camps J, Iftimie S, García-Heredia A, Castro A, Joven J.

Clin Biochem. 2017 Sep;50(13-14):804-811. doi: 10.1016/j.clinbiochem.2017.04.016. Epub 2017 Apr 19. Review.

PMID:
28433610
28.

Cocoa and Grape Seed Byproducts as a Source of Antioxidant and Anti-Inflammatory Proanthocyanidins.

Cádiz-Gurrea ML, Borrás-Linares I, Lozano-Sánchez J, Joven J, Fernández-Arroyo S, Segura-Carretero A.

Int J Mol Sci. 2017 Feb 10;18(2). pii: E376. doi: 10.3390/ijms18020376.

29.

Nutrients in Energy and One-Carbon Metabolism: Learning from Metformin Users.

Luciano-Mateo F, Hernández-Aguilera A, Cabre N, Camps J, Fernández-Arroyo S, Lopez-Miranda J, Menendez JA, Joven J.

Nutrients. 2017 Feb 10;9(2). pii: E121. doi: 10.3390/nu9020121. Review.

30.

Novel circulating biomarkers for non-alcoholic fatty liver disease: A systematic review.

Sahebkar A, Sancho E, Abelló D, Camps J, Joven J.

J Cell Physiol. 2018 Feb;233(2):849-855. doi: 10.1002/jcp.25779. Epub 2017 Mar 28. Review.

PMID:
28063221
31.
32.

Inferring propagation paths for sparsely observed perturbations on complex networks.

Massucci FA, Wheeler J, Beltrán-Debón R, Joven J, Sales-Pardo M, Guimerà R.

Sci Adv. 2016 Oct 21;2(10):e1501638. eCollection 2016 Oct.

33.

Metabolite profiling can change health-care delivery to obese patients with fatty liver disease: the search for biomarkers.

Camps J, Joven J.

Clin Chem Lab Med. 2017 Mar 1;55(4):501-506. doi: 10.1515/cclm-2016-0762. Review.

PMID:
27816954
34.

Metformin targets histone acetylation in cancer-prone epithelial cells.

Cuyàs E, Fernández-Arroyo S, Joven J, Menendez JA.

Cell Cycle. 2016 Dec 16;15(24):3355-3361. doi: 10.1080/15384101.2016.1249547. Epub 2016 Oct 28.

35.

Relationships Between Metformin, Paraoxonase-1 and the Chemokine (C-C Motif) Ligand 2.

Camps J, Hernandez-Aguilera A, Garcia-Heredia A, Cabre N, Luciano-Mateo F, Arenas M, Joven J.

Curr Clin Pharmacol. 2016;11(4):250-258. Review.

PMID:
27633039
36.

Epigenetics and nutrition-related epidemics of metabolic diseases: Current perspectives and challenges.

Hernández-Aguilera A, Fernández-Arroyo S, Cuyàs E, Luciano-Mateo F, Cabre N, Camps J, Lopez-Miranda J, Menendez JA, Joven J.

Food Chem Toxicol. 2016 Oct;96:191-204. doi: 10.1016/j.fct.2016.08.006. Epub 2016 Aug 5. Review.

PMID:
27503834
37.

Biochemical indices of oxidative stress and inflammation in the evaluation of peripheral artery disease.

Fort-Gallifa I, García-Heredia A, Hernández-Aguilera A, Simó JM, Sepúlveda J, Martín-Paredero V, Camps J, Joven J.

Free Radic Biol Med. 2016 Aug;97:568-576. doi: 10.1016/j.freeradbiomed.2016.07.011. Epub 2016 Jul 19.

PMID:
27449545
38.

Erratum to: Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria.

Iftimie S, García-Heredia A, Pujol I, Ballester F, Fort-Gallifa I, Simó JM, Joven J, Camps J, Castro A.

Eur J Clin Microbiol Infect Dis. 2016 Sep;35(9):1425. No abstract available.

PMID:
27435069
39.

Metformin and cancer: Quo vadis et cui bono?

Menendez JA, Martin-Castillo B, Joven J.

Oncotarget. 2016 Aug 23;7(34):54096-54101. doi: 10.18632/oncotarget.10262.

40.

Preliminary study on serum paraoxonase-1 status and chemokine (C-C motif) ligand 2 in hospitalized elderly patients with catheter-associated asymptomatic bacteriuria.

Iftimie S, García-Heredia A, Pujol I, Ballester F, Fort-Gallifa I, Simó JM, Joven J, Camps J, Castro A.

Eur J Clin Microbiol Infect Dis. 2016 Sep;35(9):1417-24. doi: 10.1007/s10096-016-2679-8. Epub 2016 Jun 22. Erratum in: Eur J Clin Microbiol Infect Dis. 2016 Sep;35(9):1425.

PMID:
27334497
41.

Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate.

Vazquez-Martin A, Van den Haute C, Cufí S, Corominas-Faja B, Cuyàs E, Lopez-Bonet E, Rodriguez-Gallego E, Fernández-Arroyo S, Joven J, Baekelandt V, Menendez JA.

Aging (Albany NY). 2016 Jul;8(7):1330-52. doi: 10.18632/aging.100976.

42.

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

Cuyàs E, Fernández-Arroyo S, Alarcón T, Lupu R, Joven J, Menendez JA.

Oncotarget. 2016 Aug 16;7(33):52974-52992. doi: 10.18632/oncotarget.9732.

43.

Systematic review and meta-analysis deciphering the impact of fibrates on paraoxonase-1 status.

Sahebkar A, Hernández-Aguilera A, Abelló D, Sancho E, Camps J, Joven J.

Metabolism. 2016 May;65(5):609-22. doi: 10.1016/j.metabol.2016.01.002. Epub 2016 Jan 11. Review.

PMID:
27085770
44.

Paraoxonases, mitochondrial dysfunction and non-communicable diseases.

Camps J, García-Heredia A, Hernández-Aguilera A, Joven J.

Chem Biol Interact. 2016 Nov 25;259(Pt B):382-387. doi: 10.1016/j.cbi.2016.04.005. Epub 2016 Apr 7. Review.

PMID:
27062890
45.

Metformin administration induces hepatotoxic effects in paraoxonase-1-deficient mice.

García-Heredia A, Riera-Borrull M, Fort-Gallifa I, Luciano-Mateo F, Cabré N, Hernández-Aguilera A, Joven J, Camps J.

Chem Biol Interact. 2016 Apr 5;249:56-63. doi: 10.1016/j.cbi.2016.03.004. Epub 2016 Mar 3.

PMID:
26945512
46.

Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome.

Menendez JA, Folguera-Blasco N, Cuyàs E, Fernández-Arroyo S, Joven J, Alarcón T.

Oncotarget. 2016 Mar 15;7(11):11959-71. doi: 10.18632/oncotarget.7867.

47.

Methotrexate selectively targets human proinflammatory macrophages through a thymidylate synthase/p53 axis.

Municio C, Soler Palacios B, Estrada-Capetillo L, Benguria A, Dopazo A, García-Lorenzo E, Fernández-Arroyo S, Joven J, Miranda-Carús ME, González-Álvaro I, Puig-Kröger A.

Ann Rheum Dis. 2016 Dec;75(12):2157-2165. doi: 10.1136/annrheumdis-2015-208736. Epub 2016 Feb 26.

PMID:
26920997
48.

Activation of the methylation cycle in cells reprogrammed into a stem cell-like state.

Fernández-Arroyo S, Cuyàs E, Bosch-Barrera J, Alarcón T, Joven J, Menendez JA.

Oncoscience. 2016 Jan 5;2(12):958-967. eCollection 2015.

49.

Exploring the effects of the atherosclerosis progression and the choice of affected arteries in the design of experiments with Apolipoprotein E-deficient mice.

Riera-Borrull M, Sabench F, del Castillo D, Camps J, Joven J.

Clin Investig Arterioscler. 2016 Mar-Apr;28(2):82-6. doi: 10.1016/j.arteri.2015.10.005. Epub 2016 Feb 15.

PMID:
26899621
50.

Oncometabolic Nuclear Reprogramming of Cancer Stemness.

Menendez JA, Corominas-Faja B, Cuyàs E, García MG, Fernández-Arroyo S, Fernández AF, Joven J, Fraga MF, Alarcón T.

Stem Cell Reports. 2016 Mar 8;6(3):273-83. doi: 10.1016/j.stemcr.2015.12.012. Epub 2016 Feb 11.

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