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Items: 1 to 50 of 347

1.

Clinical Relevance of Genomic Changes in Recurrent Pediatric Solid Tumors.

Lee B, Lee JW, Shim JH, Joung JG, Yun JW, Bae JS, Shin HT, Sung KW, Park WY.

Transl Oncol. 2018 Dec;11(6):1390-1397. doi: 10.1016/j.tranon.2018.08.013. Epub 2018 Sep 11.

2.

Correction: The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations in TNFAIP3 followed by mutations in TBL1XR1 and CREBBP.

Jung H, Yoo HY, Lee SH, Shin S, Kim SC, Lee S, Joung JG, Nam JY, Ryu D, Yun JW, Choi JK, Ghosh A, Kim KK, Kim SJ, Kim WS, Park WY, Ko YH.

Oncotarget. 2018 Aug 28;9(67):32882. doi: 10.18632/oncotarget.26080. eCollection 2018 Aug 28.

3.

Importance of androgen-deprivation therapy during enzalutamide treatment in men with metastatic castration-resistant prostate cancer following chemotherapy: results from retrospective, multicenter data.

Jeong CW, Kang M, Il Jung S, Kim TH, Park SW, Joung JY, Jeon SS, Hong JH, Lee JY, Chung BH, Ahn H, Kim CS, Kwon DD, Kwak C.

Prostate Cancer Prostatic Dis. 2018 Sep 13. doi: 10.1038/s41391-018-0088-z. [Epub ahead of print]

PMID:
30214035
4.

In vivo CRISPR editing with no detectable genome-wide off-target mutations.

Akcakaya P, Bobbin ML, Guo JA, Malagon-Lopez J, Clement K, Garcia SP, Fellows MD, Porritt MJ, Firth MA, Carreras A, Baccega T, Seeliger F, Bjursell M, Tsai SQ, Nguyen NT, Nitsch R, Mayr LM, Pinello L, Bohlooly-Y M, Aryee MJ, Maresca M, Joung JK.

Nature. 2018 Sep;561(7723):416-419. doi: 10.1038/s41586-018-0500-9. Epub 2018 Sep 12.

PMID:
30209390
5.

Discovery of widespread Type I and Type V CRISPR-Cas inhibitors.

Marino ND, Zhang JY, Borges AL, Sousa AA, Leon LM, Rauch BJ, Walton RT, Berry JD, Joung JK, Kleinstiver BP, Bondy-Denomy J.

Science. 2018 Sep 6. pii: eaau5174. doi: 10.1126/science.aau5174. [Epub ahead of print]

PMID:
30190308
6.

Elucidating the Role of Molecule-Electrode Interfacial Defects in Charge Tunneling Characteristics of Large-Area Junctions.

Kong GD, Jin J, Thuo M, Song H, Joung JF, Park S, Yoon HJ.

J Am Chem Soc. 2018 Sep 14. doi: 10.1021/jacs.8b08146. [Epub ahead of print]

PMID:
30183277
7.

Overcoming P-Glycoprotein-Mediated Multidrug Resistance in Colorectal Cancer: Potential Reversal Agents among Herbal Medicines.

Lee G, Joung JY, Cho JH, Son CG, Lee N.

Evid Based Complement Alternat Med. 2018 Aug 12;2018:3412074. doi: 10.1155/2018/3412074. eCollection 2018. Review.

8.

Correlations between metabolic texture features, genetic heterogeneity, and mutation burden in patients with lung cancer.

Moon SH, Kim J, Joung JG, Cha H, Park WY, Ahn JS, Ahn MJ, Park K, Choi JY, Lee KH, Kim BT, Lee SH.

Eur J Nucl Med Mol Imaging. 2018 Aug 25. doi: 10.1007/s00259-018-4138-5. [Epub ahead of print]

PMID:
30145701
9.

Significance of Intratumoral Fibrosis in Clear Cell Renal Cell Carcinoma.

Joung JW, Oh HK, Lee SJ, Kim YA, Jung HJ.

J Pathol Transl Med. 2018 Sep;52(5):323-330. doi: 10.4132/jptm.2018.07.21. Epub 2018 Aug 19.

10.

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities.

Gehrke JM, Cervantes O, Clement MK, Wu Y, Zeng J, Bauer DE, Pinello L, Joung JK.

Nat Biotechnol. 2018 Jul 30. doi: 10.1038/nbt.4199. [Epub ahead of print]

PMID:
30059493
11.

The neutrophil-to-lymphocyte ratio makes the Heng risk model improve better the prediction of overall survival in metastatic renal cell cancer patients.

Kim SH, Kwon WA, Kim S, Joung JY, Seo HK, Lee KH, Chung J.

Jpn J Clin Oncol. 2018 Sep 1;48(9):835-840. doi: 10.1093/jjco/hyy098.

PMID:
30053128
12.

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs.

Listgarten J, Weinstein M, Kleinstiver BP, Sousa AA, Joung JK, Crawford J, Gao K, Hoang L, Elibol M, Doench JG, Fusi N.

Nat Biomed Eng. 2018 Jan;2(1):38-47. doi: 10.1038/s41551-017-0178-6. Epub 2018 Jan 10.

13.

Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize.

Lee K, Zhang Y, Kleinstiver BP, Guo JA, Aryee MJ, Miller J, Malzahn A, Zarecor S, Lawrence-Dill CJ, Joung JK, Qi Y, Wang K.

Plant Biotechnol J. 2018 Jul 4. doi: 10.1111/pbi.12982. [Epub ahead of print]

14.

Efficient CRISPR/Cas9-mediated editing of trinucleotide repeat expansion in myotonic dystrophy patient-derived iPS and myogenic cells.

Dastidar S, Ardui S, Singh K, Majumdar D, Nair N, Fu Y, Reyon D, Samara E, Gerli MFM, Klein AF, De Schrijver W, Tipanee J, Seneca S, Tulalamba W, Wang H, Chai YC, In't Veld P, Furling D, Tedesco FS, Vermeesch JR, Joung JK, Chuah MK, VandenDriessche T.

Nucleic Acids Res. 2018 Sep 19;46(16):8275-8298. doi: 10.1093/nar/gky548.

PMID:
29947794
15.

Prostate stem cell antigen mRNA in blood is a predictor of survival after radical prostatectomy in patients with high-risk prostate cancer.

Suh YS, Joung JY, Kim SH, Kim JE, Choi MK, Park WS, Lee SJ, Seo HK, Chung J, Lee KH.

Oncotarget. 2018 May 29;9(41):26291-26298. doi: 10.18632/oncotarget.25207. eCollection 2018 May 29.

16.

CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.

György B, Lööv C, Zaborowski MP, Takeda S, Kleinstiver BP, Commins C, Kastanenka K, Mu D, Volak A, Giedraitis V, Lannfelt L, Maguire CA, Joung JK, Hyman BT, Breakefield XO, Ingelsson M.

Mol Ther Nucleic Acids. 2018 Jun 1;11:429-440. doi: 10.1016/j.omtn.2018.03.007. Epub 2018 Mar 16.

17.

Risk of second primary Cancer among bladder Cancer patients: a population-based cohort study in Korea.

Kwon WA, Joung JY, Lim J, Oh CM, Jung KW, Kim SH, Seo HK, Park WS, Chung J, Lee KH, Won YJ.

BMC Cancer. 2018 May 31;18(1):617. doi: 10.1186/s12885-018-4530-3.

18.

Genomic alterations of ground-glass nodular lung adenocarcinoma.

Lee H, Joung JG, Shin HT, Kim DH, Kim Y, Kim H, Kwon OJ, Shim YM, Lee HY, Lee KS, Choi YL, Park WY, Hayes DN, Um SW.

Sci Rep. 2018 May 16;8(1):7691. doi: 10.1038/s41598-018-25800-2.

19.

Molecular Characterization of Colorectal Signet-Ring Cell Carcinoma Using Whole-Exome and RNA Sequencing.

Nam JY, Oh BY, Hong HK, Bae JS, Kim TW, Ha SY, Park D, Lee WY, Kim HC, Yun SH, Park YA, Joung JG, Park WY, Cho YB.

Transl Oncol. 2018 Aug;11(4):836-844. doi: 10.1016/j.tranon.2018.04.007. Epub 2018 May 7.

20.

Temporal and Spatial Post-Transcriptional Regulation of Zebrafish tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly.

Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1562-1575. doi: 10.1161/ATVBAHA.118.310848. Epub 2018 May 3.

21.

Cationic Effect on the Equilibria and Kinetics of the Excited-State Proton Transfer Reaction of a Photoacid in Aqueous Solutions.

Joung JF, Kim S, Park S.

J Phys Chem B. 2018 May 17;122(19):5087-5093. doi: 10.1021/acs.jpcb.8b00588. Epub 2018 May 7.

PMID:
29685035
22.

An Evolutionary Theory to Explain the Mechanism of Pain Control by Acupuncture Therapy.

Joung JY, Lee NH, Son CG.

J Altern Complement Med. 2018 Jul;24(7):743-744. doi: 10.1089/acm.2017.0326. Epub 2018 Mar 14. No abstract available.

PMID:
29641243
23.

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".

Lareau CA, Clement K, Hsu JY, Pattanayak V, Joung JK, Aryee MJ, Pinello L.

Nat Methods. 2018 Apr;15(4):238-239. doi: 10.1038/nmeth.4541. Epub 2018 Mar 30. No abstract available.

PMID:
29600992
24.

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6.

Gootenberg JS, Abudayyeh OO, Kellner MJ, Joung J, Collins JJ, Zhang F.

Science. 2018 Apr 27;360(6387):439-444. doi: 10.1126/science.aaq0179. Epub 2018 Feb 15.

25.

Prognostic significance of nephrectomy in metastatic renal cell carcinoma treated with systemic cytokine or targeted therapy: A 16-year retrospective analysis.

Kim SH, Jeong KC, Joung JY, Seo HK, Lee KH, Chung J.

Sci Rep. 2018 Feb 14;8(1):2974. doi: 10.1038/s41598-018-20822-2.

26.

Probiotic and anti-inflammatory potential of Lactobacillus rhamnosus 4B15 and Lactobacillus gasseri 4M13 isolated from infant feces.

Oh NS, Joung JY, Lee JY, Kim Y.

PLoS One. 2018 Feb 14;13(2):e0192021. doi: 10.1371/journal.pone.0192021. eCollection 2018.

27.

Gene therapy comes of age.

Dunbar CE, High KA, Joung JK, Kohn DB, Ozawa K, Sadelain M.

Science. 2018 Jan 12;359(6372). pii: eaan4672. doi: 10.1126/science.aan4672. Review.

PMID:
29326244
28.

Retrospective analysis of 25 immunohistochemical tissue markers for differentiating multilocular cystic renal neoplasm of low malignant potential and multicystic renal cell carcinoma.

Kim SH, Park B, Joo J, Joung JY, Seo HK, Lee KH, Park WS, Chung J.

Histol Histopathol. 2018 Jun;33(6):589-596. doi: 10.14670/HH-11-958. Epub 2018 Jan 2.

PMID:
29292824
29.

Lifestyle Risk Prediction Model for Prostate Cancer in a Korean Population.

Kim SH, Kim S, Joung JY, Kwon WA, Seo HK, Chung J, Nam BH, Lee KH.

Cancer Res Treat. 2017 Dec 21. doi: 10.4143/crt.2017.484. [Epub ahead of print]

30.

Survival outcomes of double- and triple-sequential targeted therapy in patients with metastatic renal cell carcinoma: a retrospective comparison.

Kim SH, Suh YS, Kim JK, Joung JY, Seo HK, Lee KH, Chung J.

Oncotarget. 2017 Oct 19;8(59):100056-100065. doi: 10.18632/oncotarget.21926. eCollection 2017 Nov 21.

31.

Establishment and Application of Prostate Cancer Circulating Tumor Cells in the Era of Precision Medicine.

Suh YS, Joung JY, Kim SH, Seo HK, Chung J, Lee KH.

Biomed Res Int. 2017;2017:7206307. doi: 10.1155/2017/7206307. Epub 2017 Nov 5. Review.

32.

Recommended oral sodium bicarbonate administration for urine alkalinization did not affect the concentration of mitomycin-C in non-muscle invasive bladder cancer patients.

Seo HK, Kim SH, Ahn KO, Lee SJ, Park WS, Kim S, Hwang SH, Lee DH, Joung JY, Chung J, Joo J, Jeong KC.

Oncotarget. 2017 Oct 9;8(56):96117-96125. doi: 10.18632/oncotarget.21755. eCollection 2017 Nov 10.

33.

Nodal patterning without Lefty inhibitory feedback is functional but fragile.

Rogers KW, Lord ND, Gagnon JA, Pauli A, Zimmerman S, Aksel DC, Reyon D, Tsai SQ, Joung JK, Schier AF.

Elife. 2017 Dec 7;6. pii: e28785. doi: 10.7554/eLife.28785.

34.

A retrospective comparative study of progression-free survival and overall survival between metachronous and synchronous metastatic renal cell carcinoma in intermediate- or poor-risk patients treated with VEGF-targeted therapy.

Kim SH, Suh YS, Lee DE, Park B, Joo J, Joung JY, Seo HK, Lee KH, Chung J.

Oncotarget. 2017 Sep 6;8(55):93633-93643. doi: 10.18632/oncotarget.20674. eCollection 2017 Nov 7.

35.

SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells.

Han KY, Kim KT, Joung JG, Son DS, Kim YJ, Jo A, Jeon HJ, Moon HS, Yoo CE, Chung W, Eum HH, Kim S, Kim HK, Lee JE, Ahn MJ, Lee HO, Park D, Park WY.

Genome Res. 2018 Jan;28(1):75-87. doi: 10.1101/gr.223263.117. Epub 2017 Dec 5.

36.

Exome and transcriptome sequencing identifies loss of PDLIM2 in metastatic colorectal cancers.

Oh BY, Cho J, Hong HK, Bae JS, Park WY, Joung JG, Cho YB.

Cancer Manag Res. 2017 Nov 8;9:581-589. doi: 10.2147/CMAR.S149002. eCollection 2017.

37.

Prevalence and detection of low-allele-fraction variants in clinical cancer samples.

Shin HT, Choi YL, Yun JW, Kim NKD, Kim SY, Jeon HJ, Nam JY, Lee C, Ryu D, Kim SC, Park K, Lee E, Bae JS, Son DS, Joung JG, Lee J, Kim ST, Ahn MJ, Lee SH, Ahn JS, Lee WY, Oh BY, Park YH, Lee JE, Lee KH, Kim HC, Kim KM, Im YH, Park K, Park PJ, Park WY.

Nat Commun. 2017 Nov 9;8(1):1377. doi: 10.1038/s41467-017-01470-y.

38.

Inducible and multiplex gene regulation using CRISPR-Cpf1-based transcription factors.

Tak YE, Kleinstiver BP, Nuñez JK, Hsu JY, Horng JE, Gong J, Weissman JS, Joung JK.

Nat Methods. 2017 Dec;14(12):1163-1166. doi: 10.1038/nmeth.4483. Epub 2017 Oct 30.

39.

RNA editing with CRISPR-Cas13.

Cox DBT, Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, Zhang F.

Science. 2017 Nov 24;358(6366):1019-1027. doi: 10.1126/science.aaq0180. Epub 2017 Oct 25.

40.

RNA targeting with CRISPR-Cas13.

Abudayyeh OO, Gootenberg JS, Essletzbichler P, Han S, Joung J, Belanto JJ, Verdine V, Cox DBT, Kellner MJ, Regev A, Lander ES, Voytas DF, Ting AY, Zhang F.

Nature. 2017 Oct 12;550(7675):280-284. doi: 10.1038/nature24049. Epub 2017 Oct 4.

41.

Prevalence and survival prognosis of prostate cancer in patients with end-stage renal disease: a retrospective study based on the Korea national database (2003-2010).

Kim SH, Joung JY, Suh YS, Kim YA, Hong JH, Kuark TS, Lee ES, Lee KH.

Oncotarget. 2017 Jul 22;8(38):64250-64262. doi: 10.18632/oncotarget.19453. eCollection 2017 Sep 8.

42.

Optical Coherence Tomography Protocols for Screening of Hydroxychloroquine Retinopathy in Asian Patients.

Ahn SJ, Joung J, Lim HW, Lee BR.

Am J Ophthalmol. 2017 Dec;184:11-18. doi: 10.1016/j.ajo.2017.09.025. Epub 2017 Sep 28.

PMID:
28964805
43.

Tumor Heterogeneity Predicts Metastatic Potential in Colorectal Cancer.

Joung JG, Oh BY, Hong HK, Al-Khalidi H, Al-Alem F, Lee HO, Bae JS, Kim J, Cha HU, Alotaibi M, Cho YB, Hassanain M, Park WY, Lee WY.

Clin Cancer Res. 2017 Dec 1;23(23):7209-7216. doi: 10.1158/1078-0432.CCR-17-0306. Epub 2017 Sep 22.

PMID:
28939741
44.

Erratum: Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.

Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F.

Nature. 2017 Sep 20;549(7672):418. doi: 10.1038/nature24009.

PMID:
28933431
45.

Retrograde pyelography predicts retrograde ureteral stenting failure and reduces unnecessary stenting trials in patients with advanced non-urological malignant ureteral obstruction.

Kim SH, Park B, Joo J, Joung JY, Seo HK, Chung J, Lee KH.

PLoS One. 2017 Sep 20;12(9):e0184965. doi: 10.1371/journal.pone.0184965. eCollection 2017.

46.

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.

Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA.

Nature. 2017 Oct 19;550(7676):407-410. doi: 10.1038/nature24268. Epub 2017 Sep 20.

47.

Ionic effects on the proton transfer mechanism in aqueous solutions.

Joung JF, Kim S, Park S.

Phys Chem Chem Phys. 2017 Sep 27;19(37):25509-25517. doi: 10.1039/c7cp04392a.

PMID:
28900649
48.

Choroidal Thinning Associated With Hydroxychloroquine Retinopathy.

Ahn SJ, Ryu SJ, Joung JY, Lee BR.

Am J Ophthalmol. 2017 Nov;183:56-64. doi: 10.1016/j.ajo.2017.08.022. Epub 2017 Sep 8.

PMID:
28890078
49.

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood.

Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F.

Nature. 2017 Aug 17;548(7667):343-346. doi: 10.1038/nature23451. Epub 2017 Aug 11. Erratum in: Nature. 2017 Sep 20;549(7672):418.

50.

A Method to Evaluate the Quality of Clinical Gene-Panel Sequencing Data for Single-Nucleotide Variant Detection.

Lee C, Bae JS, Ryu GH, Kim NKD, Park D, Chung J, Kyung S, Joung JG, Shin HT, Shin SH, Kim Y, Kim BS, Lee H, Kim KM, Kim JS, Park WY, Son DS.

J Mol Diagn. 2017 Sep;19(5):651-658. doi: 10.1016/j.jmoldx.2017.06.001. Epub 2017 Jul 22.

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