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Gene expression and DNA methylation regulation of arsenic in mouse bladder tissues and in human urothelial cells.

Jou YC, Wang SC, Dai YC, Chen SY, Shen CH, Lee YR, Chen LC, Liu YW.

Oncol Rep. 2019 Sep;42(3):1005-1016. doi: 10.3892/or.2019.7235. Epub 2019 Jul 16.


A New Switch for TGFβ in Cancer.

Yeh HW, Lee SS, Chang CY, Lang YD, Jou YS.

Cancer Res. 2019 Aug 1;79(15):3797-3805. doi: 10.1158/0008-5472.CAN-18-2019. Epub 2019 Jul 12. Review.


An integrated model using the Taguchi method and artificial neural network to improve artificial kidney solidification parameters.

Shie AJ, Lo KH, Lin WT, Juan CW, Jou YT.

Biomed Eng Online. 2019 Jul 5;18(1):78. doi: 10.1186/s12938-019-0696-4.


Indoleamine-2,3-dioxygenase-1 expression predicts poorer survival and up-regulates ZEB2 expression in human early stage bladder cancer.

Tsai YS, Jou YC, Tsai HT, Cheong IS, Tzai TS.

Urol Oncol. 2019 Jun 25. pii: S1078-1439(19)30191-7. doi: 10.1016/j.urolonc.2019.05.005. [Epub ahead of print]


Targeting Protein Tyrosine Phosphatase PTP-PEST for Therapeutic Intervention in Acute Myocardial Infarction.

Yang CF, Chen YY, Singh JP, Hsu SF, Liu YW, Yang CY, Chang CW, Chen SN, Shih RH, Hsu SD, Jou YS, Cheng CF, Meng TC.

Cardiovasc Res. 2019 Jun 22. pii: cvz165. doi: 10.1093/cvr/cvz165. [Epub ahead of print]


History of Urinary Retention Is a Risk Factor for Infection after Prostate Biopsy: A Nationwide, Population-Based Cohort Study.

Lin SL, Lin CT, Huang WT, Jou YC, Tzai TS, Tsai YS.

Surg Infect (Larchmt). 2019 Apr;20(3):202-207. doi: 10.1089/sur.2018.174. Epub 2018 Dec 27.


Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma.

Dimopoulos MA, Dytfeld D, Grosicki S, Moreau P, Takezako N, Hori M, Leleu X, LeBlanc R, Suzuki K, Raab MS, Richardson PG, Popa McKiver M, Jou YM, Shelat SG, Robbins M, Rafferty B, San-Miguel J.

N Engl J Med. 2018 Nov 8;379(19):1811-1822. doi: 10.1056/NEJMoa1805762.


Cis-3-O-p-hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells.

Wang CY, Lin CS, Hua CH, Jou YJ, Liao CR, Chang YS, Wan L, Huang SH, Hour MJ, Lin CW.

Biomol Ther (Seoul). 2019 Jan 1;27(1):54-62. doi: 10.4062/biomolther.2017.237.


PSPC1 potentiates TGF-β-dependent metastatic dissemination.

Yeh HW, Jou YS.

Mol Cell Oncol. 2018 Aug 1;5(4):e1472058. doi: 10.1080/23723556.2018.1472058. eCollection 2018.


Ureteroscope-aided Reinsertion of Dislodged Pigtail Nephrostomy Tube Through Collapsed Tract.

Chang SK, Chen BJ, Jou YC, Li MC, Chen PY.

Urol J. 2019 Jun 17;16(3):251-254. doi: 10.22037/uj.v0i0.4258.


Mutations in NOTCH1 and nucleotide excision repair genes are correlated with prognosis of hepatitis B virus-associated hepatocellular carcinoma.

Su WH, Jou YS, Zhang JH, Ho CM, Tai DI.

J Cancer. 2018 Jun 23;9(15):2678-2686. doi: 10.7150/jca.25438. eCollection 2018.


LPA1/3 signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer.

Lin YC, Chen CC, Chen WM, Lu KY, Shen TL, Jou YC, Shen CH, Ohbayashi N, Kanaho Y, Huang YL, Lee H.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Oct;1863(10):1305-1315. doi: 10.1016/j.bbalip.2018.07.005. Epub 2018 Jul 24.


Elotuzumab monotherapy in patients with smouldering multiple myeloma: a phase 2 study.

Jagannath S, Laubach J, Wong E, Stockerl-Goldstein K, Rosenbaum C, Dhodapkar M, Jou YM, Lynch M, Robbins M, Shelat S, Anderson KC, Richardson PG.

Br J Haematol. 2018 Aug;182(4):495-503. doi: 10.1111/bjh.15384. Epub 2018 May 29.


Dental deafferentation and brain damage: A review and a hypothesis.

Jou YT.

Kaohsiung J Med Sci. 2018 Apr;34(4):231-237. doi: 10.1016/j.kjms.2018.01.013. Epub 2018 Feb 8. Review.


Brain metastasis from renal urothelial carcinoma successfully treated by metastasectomy.

Fang WK, Jou YC, Dai YC, Ko PC, Huang YF.

Ci Ji Yi Xue Za Zhi. 2018 Jan-Mar;30(1):41-43. doi: 10.4103/tcmj.tcmj_82_17.


PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis.

Yeh HW, Hsu EC, Lee SS, Lang YD, Lin YC, Chang CY, Lee SY, Gu DL, Shih JH, Ho CM, Chen CF, Chen CT, Tu PH, Cheng CF, Chen RH, Yang RB, Jou YS.

Nat Cell Biol. 2018 Apr;20(4):479-491. doi: 10.1038/s41556-018-0062-y. Epub 2018 Mar 28.


EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma.

Lee HY, Chen CK, Ho CM, Lee SS, Chang CY, Chen KJ, Jou YS.

Oncotarget. 2018 Jan 11;9(17):13193-13205. doi: 10.18632/oncotarget.24149. eCollection 2018 Mar 2.


CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular Carcinoma.

Shen ZQ, Chen YF, Chen JR, Jou YS, Wu PC, Kao CH, Wang CH, Huang YL, Chen CF, Huang TS, Shyu YC, Tsai SF, Kao LS, Tsai TF.

Cell Rep. 2017 Nov 21;21(8):2198-2211. doi: 10.1016/j.celrep.2017.10.099.


Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis.

Yeh HW, Lee SS, Chang CY, Hu CM, Jou YS.

Oncotarget. 2017 Sep 8;8(44):77734-77751. doi: 10.18632/oncotarget.20774. eCollection 2017 Sep 29.


Epigenetic silencing of the dual-role signal mediator, ANGPTL4 in tumor tissues and its overexpression in the urothelial carcinoma microenvironment.

Hsieh HY, Jou YC, Tung CL, Tsai YS, Wang YH, Chi CL, Lin RI, Hung SK, Chuang YM, Wu SF, Li C, Shen CH, Chan MWY, Hsu CD.

Oncogene. 2018 Feb 1;37(5):673-686. doi: 10.1038/onc.2017.375. Epub 2017 Oct 16.


Phase 1 safety, pharmacokinetic and pharmacodynamic study of the cyclin-dependent kinase inhibitor dinaciclib administered every three weeks in patients with advanced malignancies.

Mita MM, Mita AC, Moseley JL, Poon J, Small KA, Jou YM, Kirschmeier P, Zhang D, Zhu Y, Statkevich P, Sankhala KK, Sarantopoulos J, Cleary JM, Chirieac LR, Rodig SJ, Bannerji R, Shapiro GI.

Br J Cancer. 2017 Oct 24;117(9):1258-1268. doi: 10.1038/bjc.2017.288. Epub 2017 Aug 31.


Pneumomediastinum: An unusual complication after percutaneous nephrolithotomy.

Chang CH, Jou YC, Wu CH, Hsieh CW.

Ci Ji Yi Xue Za Zhi. 2017 Apr-Jun;29(2):118-120. doi: 10.4103/tcmj.tcmj_24_17.


Surgical treatment for urinary incontinence after prostatectomy: A meta-analysis and systematic review.

Chen YC, Lin PH, Jou YY, Lin VC.

PLoS One. 2017 May 3;12(5):e0130867. doi: 10.1371/journal.pone.0130867. eCollection 2017. Review.


Identification of novel cancer fusion genes using chromosome breakpoint screening.

Hua K, Lin CH, Chen YL, Lin CH, Ping YH, Jou YS, Chen CF.

Oncol Rep. 2017 Apr;37(4):2101-2108. doi: 10.3892/or.2017.5492. Epub 2017 Mar 6.


Population-based screening program for reducing oral cancer mortality in 2,334,299 Taiwanese cigarette smokers and/or betel quid chewers.

Chuang SL, Su WW, Chen SL, Yen AM, Wang CP, Fann JC, Chiu SY, Lee YC, Chiu HM, Chang DC, Jou YY, Wu CY, Chen HH, Chen MK, Chiou ST.

Cancer. 2017 May 1;123(9):1597-1609. doi: 10.1002/cncr.30517. Epub 2017 Jan 5.


Genome-wide linkage analysis and regional fine mapping identified variants in the RYR3 gene as a novel quantitative trait locus for circulating adiponectin in Chinese population.

Chang YC, Chiu YF, He CT, Sheu WH, Lin MW, Seto TB, Assimes T, Jou YS, Su L, Lee WJ, Lee PC, Tsai SH, Chuang LM.

Medicine (Baltimore). 2016 Nov;95(44):e5174.


Effects of elotuzumab on QT interval and cardiac safety in patients with multiple myeloma.

Passey C, Darbenzio R, Jou YM, Lynch M, Gupta M.

Cancer Chemother Pharmacol. 2016 Dec;78(6):1237-1244. doi: 10.1007/s00280-016-3182-8. Epub 2016 Oct 28.


Foxp3 enhances HIF-1α target gene expression in human bladder cancer through decreasing its ubiquitin-proteasomal degradation.

Jou YC, Tsai YS, Lin CT, Tung CL, Shen CH, Tsai HT, Yang WH, Chang HI, Chen SY, Tzai TS.

Oncotarget. 2016 Oct 4;7(40):65403-65417. doi: 10.18632/oncotarget.11395.


Reversible acute renal failure in a patient with acquired aortic coarctation.

Lai CH, Tseng TW, Jou YL, Lu TM, Lee WL, Sung SH.

Int J Cardiol. 2016 Nov 1;222:683-685. doi: 10.1016/j.ijcard.2016.08.014. Epub 2016 Aug 4. No abstract available.


FNDC3B promotes cell migration and tumor metastasis in hepatocellular carcinoma.

Lin CH, Lin YW, Chen YC, Liao CC, Jou YS, Hsu MT, Chen CF.

Oncotarget. 2016 Aug 2;7(31):49498-49508. doi: 10.18632/oncotarget.10374.


SPANXA suppresses EMT by inhibiting c-JUN/SNAI2 signaling in lung adenocarcinoma.

Hsiao YJ, Su KY, Hsu YC, Chang GC, Chen JS, Chen HY, Hong QS, Hsu SC, Kang PH, Hsu CY, Ho BC, Yang TH, Wang CY, Jou YS, Yang PC, Yu SL.

Oncotarget. 2016 Jul 12;7(28):44417-44429. doi: 10.18632/oncotarget.10088.


Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss.

Cheng TL, Lai CH, Shieh SJ, Jou YB, Yeh JL, Yang AL, Wang YH, Wang CZ, Chen CH, Shi GY, Ho ML, Wu HL.

Sci Rep. 2016 Jun 17;6:28340. doi: 10.1038/srep28340.


Xist reduction in breast cancer upregulates AKT phosphorylation via HDAC3-mediated repression of PHLPP1 expression.

Huang YS, Chang CC, Lee SS, Jou YS, Shih HM.

Oncotarget. 2016 Jul 12;7(28):43256-43266. doi: 10.18632/oncotarget.9673.


Randomized clinical trial of the safety and efficacy of sitagliptin and metformin co-administered to Chinese patients with type 2 diabetes mellitus.

Ji L, Han P, Wang X, Liu J, Zheng S, Jou YM, O'Neill EA, Golm GT, Engel SS, Kaufman KD, Shankar RR.

J Diabetes Investig. 2016 Sep;7(5):727-36. doi: 10.1111/jdi.12511. Epub 2016 May 19.


SARS coronavirus papain-like protease induces Egr-1-dependent up-regulation of TGF-β1 via ROS/p38 MAPK/STAT3 pathway.

Li SW, Wang CY, Jou YJ, Yang TC, Huang SH, Wan L, Lin YJ, Lin CW.

Sci Rep. 2016 May 13;6:25754. doi: 10.1038/srep25754.


SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6.

Li SW, Wang CY, Jou YJ, Huang SH, Hsiao LH, Wan L, Lin YJ, Kung SH, Lin CW.

Int J Mol Sci. 2016 May 5;17(5). pii: E678. doi: 10.3390/ijms17050678.


Anticancer Activity of γ-Bisabolene in Human Neuroblastoma Cells via Induction of p53-Mediated Mitochondrial Apoptosis.

Jou YJ, Hua CH, Lin CS, Wang CY, Wan L, Lin YJ, Huang SH, Lin CW.

Molecules. 2016 May 7;21(5). pii: E601. doi: 10.3390/molecules21050601.


Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MM.

Jakubowiak A, Offidani M, Pégourie B, De La Rubia J, Garderet L, Laribi K, Bosi A, Marasca R, Laubach J, Mohrbacher A, Carella AM, Singhal AK, Tsao LC, Lynch M, Bleickardt E, Jou YM, Robbins M, Palumbo A.

Blood. 2016 Jun 9;127(23):2833-40. doi: 10.1182/blood-2016-01-694604. Epub 2016 Apr 18.


Loss of DAB2IP expression in human urothelial carcinoma is associated with poorer recurrence-free survival.

Jou YC, Tsai YS, Chen SY, Hsieh HY, Tsai HT, Tzai TS.

Virchows Arch. 2016 Jun;468(6):733-40. doi: 10.1007/s00428-016-1924-y. Epub 2016 Mar 22.


Feasibility Testing: Three-dimensional Tumor Mapping in Different Orientations of Automated Breast Ultrasound.

Lo CM, Chan SW, Yang YW, Chang YC, Huang CS, Jou YS, Chang RF.

Ultrasound Med Biol. 2016 May;42(5):1201-10. doi: 10.1016/j.ultrasmedbio.2015.12.006. Epub 2016 Jan 26.


Genetic polymorphisms of PCSK2 are associated with glucose homeostasis and progression to type 2 diabetes in a Chinese population.

Chang TJ, Chiu YF, Sheu WH, Shih KC, Hwu CM, Quertermous T, Jou YS, Kuo SS, Chang YC, Chuang LM.

Sci Rep. 2015 Nov 26;5:14380. doi: 10.1038/srep14380.


High resolution absolute absorption cross sections of the B ̃(1)A'-X ̃(1)A' transition of the CH2OO biradical.

Foreman ES, Kapnas KM, Jou Y, Kalinowski J, Feng D, Gerber RB, Murray C.

Phys Chem Chem Phys. 2015 Dec 28;17(48):32539-46. doi: 10.1039/c5cp04977f. Epub 2015 Nov 23.


Methylomics analysis identifies ZNF671 as an epigenetically repressed novel tumor suppressor and a potential non-invasive biomarker for the detection of urothelial carcinoma.

Yeh CM, Chen PC, Hsieh HY, Jou YC, Lin CT, Tsai MH, Huang WY, Wang YT, Lin RI, Chen SS, Tung CL, Wu SF, Chang DC, Shen CH, Hsu CD, Chan MW.

Oncotarget. 2015 Oct 6;6(30):29555-72. doi: 10.18632/oncotarget.4986.


Quantitative phosphoproteomic analysis reveals γ-bisabolene inducing p53-mediated apoptosis of human oral squamous cell carcinoma via HDAC2 inhibition and ERK1/2 activation.

Jou YJ, Chen CJ, Liu YC, Way TD, Lai CH, Hua CH, Wang CY, Huang SH, Kao JY, Lin CW.

Proteomics. 2015 Oct;15(19):3296-309. doi: 10.1002/pmic.201400568. Epub 2015 Aug 13.


Loss of PTPRM associates with the pathogenic development of colorectal adenoma-carcinoma sequence.

Sudhir PR, Lin ST, Chia-Wen C, Yang SH, Li AF, Lai RH, Wang MJ, Chen YT, Chen CF, Jou YS, Chen JY.

Sci Rep. 2015 Apr 24;5:9633. doi: 10.1038/srep09633.


Contributing factors for fever after tubeless percutaneous nephrolithotomy.

Jou YC, Lu CL, Chen FH, Shen CH, Cheng MC, Lin SH, Chuang SC, Li YH.

Urology. 2015 Mar;85(3):527-30. doi: 10.1016/j.urology.2014.10.032. Epub 2014 Nov 1.


Antitumor activity in RAS-driven tumors by blocking AKT and MEK.

Tolcher AW, Khan K, Ong M, Banerji U, Papadimitrakopoulou V, Gandara DR, Patnaik A, Baird RD, Olmos D, Garrett CR, Skolnik JM, Rubin EH, Smith PD, Huang P, Learoyd M, Shannon KA, Morosky A, Tetteh E, Jou YM, Papadopoulos KP, Moreno V, Kaiser B, Yap TA, Yan L, de Bono JS.

Clin Cancer Res. 2015 Feb 15;21(4):739-48. doi: 10.1158/1078-0432.CCR-14-1901. Epub 2014 Dec 16.


S100A8 as potential salivary biomarker of oral squamous cell carcinoma using nanoLC-MS/MS.

Jou YJ, Hua CH, Lin CD, Lai CH, Huang SH, Tsai MH, Kao JY, Lin CW.

Clin Chim Acta. 2014 Sep 25;436:121-9. doi: 10.1016/j.cca.2014.05.009. Epub 2014 May 24.


Loss of nuclear prothymosin-α expression is associated with disease progression in human superficial bladder cancer.

Tsai YS, Jou YC, Tung CL, Lin CT, Shen CH, Chen SY, Tsai HT, Lai CL, Wu CL, Tzai TS.

Virchows Arch. 2014 Jun;464(6):717-24. doi: 10.1007/s00428-014-1578-6. Epub 2014 Apr 15.


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