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Items: 10

1.

Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms.

Keller AN, Kufareva I, Josephs TM, Diao J, Mai VT, Conigrave AD, Christopoulos A, Gregory KJ, Leach K.

Mol Pharmacol. 2018 Jun;93(6):619-630. doi: 10.1124/mol.118.112086. Epub 2018 Apr 10.

PMID:
29636377
2.

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.

Van Braeckel-Budimir N, Gras S, Ladell K, Josephs TM, Pewe L, Urban SL, Miners KL, Farenc C, Price DA, Rossjohn J, Harty JT.

Immunity. 2017 Nov 21;47(5):835-847.e4. doi: 10.1016/j.immuni.2017.10.013. Epub 2017 Nov 14.

PMID:
29150238
3.

Molecular challenges imposed by MHC-I restricted long epitopes on T cell immunity.

Josephs TM, Grant EJ, Gras S.

Biol Chem. 2017 Aug 28;398(9):1027-1036. doi: 10.1515/hsz-2016-0305. Review.

PMID:
28141543
4.

Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response.

Gras S, Chadderton J, Del Campo CM, Farenc C, Wiede F, Josephs TM, Sng XYX, Mirams M, Watson KA, Tiganis T, Quinn KM, Rossjohn J, La Gruta NL.

Immunity. 2016 Oct 18;45(4):749-760. doi: 10.1016/j.immuni.2016.09.007. Epub 2016 Oct 4.

5.

Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct αβT Cell Receptor Signatures.

Grant EJ, Josephs TM, Valkenburg SA, Wooldridge L, Hellard M, Rossjohn J, Bharadwaj M, Kedzierska K, Gras S.

J Biol Chem. 2016 Nov 18;291(47):24335-24351. Epub 2016 Sep 19.

6.

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses.

Valkenburg SA, Josephs TM, Clemens EB, Grant EJ, Nguyen TH, Wang GC, Price DA, Miller A, Tong SY, Thomas PG, Doherty PC, Rossjohn J, Gras S, Kedzierska K.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4440-5. doi: 10.1073/pnas.1603106113. Epub 2016 Mar 31.

7.

HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.

Du VY, Bansal A, Carlson J, Salazar-Gonzalez JF, Salazar MG, Ladell K, Gras S, Josephs TM, Heath SL, Price DA, Rossjohn J, Hunter E, Goepfert PA.

J Immunol. 2016 Apr 15;196(8):3276-86. doi: 10.4049/jimmunol.1502411. Epub 2016 Mar 16.

8.

Interspecies Variation in the Functional Consequences of Mutation of Cytochrome c.

Josephs TM, Hibbs ME, Ong L, Morison IM, Ledgerwood EC.

PLoS One. 2015 Jun 18;10(6):e0130292. doi: 10.1371/journal.pone.0130292. eCollection 2015.

9.

Enhancing the peroxidase activity of cytochrome c by mutation of residue 41: implications for the peroxidase mechanism and cytochrome c release.

Josephs TM, Morison IM, Day CL, Wilbanks SM, Ledgerwood EC.

Biochem J. 2014 Mar 1;458(2):259-65. doi: 10.1042/BJ20131386.

PMID:
24329121
10.

Conformational change and human cytochrome c function: mutation of residue 41 modulates caspase activation and destabilizes Met-80 coordination.

Josephs TM, Liptak MD, Hughes G, Lo A, Smith RM, Wilbanks SM, Bren KL, Ledgerwood EC.

J Biol Inorg Chem. 2013 Mar;18(3):289-97. doi: 10.1007/s00775-012-0973-1. Epub 2013 Jan 19.

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