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Items: 1 to 50 of 77

1.

The core genome m5C methyltransferase JHP1050 (M.Hpy99III) plays an important role in orchestrating gene expression in Helicobacter pylori.

Estibariz I, Overmann A, Ailloud F, Krebes J, Josenhans C, Suerbaum S.

Nucleic Acids Res. 2019 Mar 18;47(5):2336-2348. doi: 10.1093/nar/gky1307.

2.

Functional expression of TLR5 of different vertebrate species and diversification in intestinal pathogen recognition.

Faber E, Tedin K, Speidel Y, Brinkmann MM, Josenhans C.

Sci Rep. 2018 Jul 26;8(1):11287. doi: 10.1038/s41598-018-29371-0.

3.

Biochemical characterization of the Helicobacter pylori Cag Type 4 Secretion System protein CagN and its interaction partner CagM.

Bats SH, Bergé C, Coombs N, Terradot L, Josenhans C.

Int J Med Microbiol. 2018 Jun;308(4):425-437. doi: 10.1016/j.ijmm.2018.02.005. Epub 2018 Mar 6.

PMID:
29572102
4.

C-Type Lectin Receptor (CLR)-Fc Fusion Proteins As Tools to Screen for Novel CLR/Bacteria Interactions: An Exemplary Study on Preselected Campylobacter jejuni Isolates.

Mayer S, Moeller R, Monteiro JT, Ellrott K, Josenhans C, Lepenies B.

Front Immunol. 2018 Feb 13;9:213. doi: 10.3389/fimmu.2018.00213. eCollection 2018.

5.

Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis.

Stein SC, Faber E, Bats SH, Murillo T, Speidel Y, Coombs N, Josenhans C.

PLoS Pathog. 2017 Jul 17;13(7):e1006514. doi: 10.1371/journal.ppat.1006514. eCollection 2017 Jul.

6.

A combined case-control and molecular source attribution study of human Campylobacter infections in Germany, 2011-2014.

Rosner BM, Schielke A, Didelot X, Kops F, Breidenbach J, Willrich N, Gölz G, Alter T, Stingl K, Josenhans C, Suerbaum S, Stark K.

Sci Rep. 2017 Jul 11;7(1):5139. doi: 10.1038/s41598-017-05227-x.

7.

Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains.

Bönig T, Olbermann P, Bats SH, Fischer W, Josenhans C.

Sci Rep. 2016 Dec 6;6:38101. doi: 10.1038/srep38101.

8.

Novel Immunomodulatory Flagellin-Like Protein FlaC in Campylobacter jejuni and Other Campylobacterales.

Faber E, Gripp E, Maurischat S, Kaspers B, Tedin K, Menz S, Zuraw A, Kershaw O, Yang I, Rautenschlein S, Josenhans C.

mSphere. 2015 Dec 2;1(1). pii: e00028-15. doi: 10.1128/mSphere.00028-15. eCollection 2016 Jan-Feb.

9.

Localisation and protein-protein interactions of the Helicobacter pylori taxis sensor TlpD and their connection to metabolic functions.

Behrens W, Schweinitzer T, McMurry JL, Loewen PC, Buettner FF, Menz S, Josenhans C.

Sci Rep. 2016 Apr 5;6:23582. doi: 10.1038/srep23582.

10.

Crosstalk between microbiota, pathogens and the innate immune responses.

Günther C, Josenhans C, Wehkamp J.

Int J Med Microbiol. 2016 Aug;306(5):257-265. doi: 10.1016/j.ijmm.2016.03.003. Epub 2016 Mar 5. Review.

PMID:
26996809
11.

Different gastric microbiota compositions in two human populations with high and low gastric cancer risk in Colombia.

Yang I, Woltemate S, Piazuelo MB, Bravo LE, Yepez MC, Romero-Gallo J, Delgado AG, Wilson KT, Peek RM, Correa P, Josenhans C, Fox JG, Suerbaum S.

Sci Rep. 2016 Jan 5;6:18594. doi: 10.1038/srep18594.

12.

Erratum for Nell et al., Dynamics of Lewis b Binding and Sequence Variation of the babA Adhesin Gene during Chronic Helicobacter pylori Infection in Humans.

Nell S, Kennemann L, Schwarz S, Josenhans C, Suerbaum S.

mBio. 2015 Sep 15;6(5):e01233-15. doi: 10.1128/mBio.01233-15. No abstract available.

13.

Dynamics of Lewis b binding and sequence variation of the babA adhesin gene during chronic Helicobacter pylori infection in humans.

Nell S, Kennemann L, Schwarz S, Josenhans C, Suerbaum S.

mBio. 2014 Dec 16;5(6). pii: e02281-14. doi: 10.1128/mBio.02281-14. Erratum in: MBio. 2015;6(5):e01233-15.

14.

Relevance of Campylobacter to public health--the need for a One Health approach.

Gölz G, Rosner B, Hofreuter D, Josenhans C, Kreienbrock L, Löwenstein A, Schielke A, Stark K, Suerbaum S, Wieler LH, Alter T.

Int J Med Microbiol. 2014 Oct;304(7):817-23. doi: 10.1016/j.ijmm.2014.08.015. Epub 2014 Aug 30. Review.

PMID:
25266744
15.

Pathogenesis of Helicobacter pylori infection.

de Bernard M, Josenhans C.

Helicobacter. 2014 Sep;19 Suppl 1:11-8. doi: 10.1111/hel.12160. Review.

PMID:
25167940
16.

Utilization of host-derived cysteine-containing peptides overcomes the restricted sulphur metabolism of Campylobacter jejuni.

Vorwerk H, Mohr J, Huber C, Wensel O, Schmidt-Hohagen K, Gripp E, Josenhans C, Schomburg D, Eisenreich W, Hofreuter D.

Mol Microbiol. 2014 Sep;93(6):1224-45. doi: 10.1111/mmi.12732. Epub 2014 Aug 25.

17.

Helicobacter hepaticus induces an inflammatory response in primary human hepatocytes.

Kleine M, Worbs T, Schrem H, Vondran FW, Kaltenborn A, Klempnauer J, Förster R, Josenhans C, Suerbaum S, Bektas H.

PLoS One. 2014 Jun 16;9(6):e99713. doi: 10.1371/journal.pone.0099713. eCollection 2014.

18.

The complex methylome of the human gastric pathogen Helicobacter pylori.

Krebes J, Morgan RD, Bunk B, Spröer C, Luong K, Parusel R, Anton BP, König C, Josenhans C, Overmann J, Roberts RJ, Korlach J, Suerbaum S.

Nucleic Acids Res. 2014 Feb;42(4):2415-32. doi: 10.1093/nar/gkt1201. Epub 2013 Dec 2.

19.

Endotoxicity of lipopolysaccharide as a determinant of T-cell-mediated colitis induction in mice.

Gronbach K, Flade I, Holst O, Lindner B, Ruscheweyh HJ, Wittmann A, Menz S, Schwiertz A, Adam P, Stecher B, Josenhans C, Suerbaum S, Gruber AD, Kulik A, Huson D, Autenrieth IB, Frick JS.

Gastroenterology. 2014 Mar;146(3):765-75. doi: 10.1053/j.gastro.2013.11.033. Epub 2013 Nov 21.

20.

A tale of two machines: a review of the BLAST meeting, Tucson, AZ, 20-24 January 2013.

Josenhans C, Jung K, Rao CV, Wolfe AJ.

Mol Microbiol. 2014 Jan;91(1):6-25. doi: 10.1111/mmi.12427. Epub 2013 Oct 31. Review. Erratum in: Mol Microbiol. 2014 Feb;91(4):852.

21.

Intestinal microbiota composition of interleukin-10 deficient C57BL/6J mice and susceptibility to Helicobacter hepaticus-induced colitis.

Yang I, Eibach D, Kops F, Brenneke B, Woltemate S, Schulze J, Bleich A, Gruber AD, Muthupalani S, Fox JG, Josenhans C, Suerbaum S.

PLoS One. 2013 Aug 9;8(8):e70783. doi: 10.1371/journal.pone.0070783. eCollection 2013.

22.

Role of energy sensor TlpD of Helicobacter pylori in gerbil colonization and genome analyses after adaptation in the gerbil.

Behrens W, Schweinitzer T, Bal J, Dorsch M, Bleich A, Kops F, Brenneke B, Didelot X, Suerbaum S, Josenhans C.

Infect Immun. 2013 Oct;81(10):3534-51. doi: 10.1128/IAI.00750-13. Epub 2013 Jul 8.

23.

Hcp and VgrG1 are secreted components of the Helicobacter hepaticus type VI secretion system and VgrG1 increases the bacterial colitogenic potential.

Bartonickova L, Sterzenbach T, Nell S, Kops F, Schulze J, Venzke A, Brenneke B, Bader S, Gruber AD, Suerbaum S, Josenhans C.

Cell Microbiol. 2013 Jun;15(6):992-1011. doi: 10.1111/cmi.12094. Epub 2013 Jan 17.

PMID:
23278999
24.

Helicobacter pylori colonization critically depends on postprandial gastric conditions.

Bücker R, Azevedo-Vethacke M, Groll C, Garten D, Josenhans C, Suerbaum S, Schreiber S.

Sci Rep. 2012;2:994. doi: 10.1038/srep00994. Epub 2012 Dec 18.

25.

In vivo sequence variation in HopZ, a phase-variable outer membrane protein of Helicobacter pylori.

Kennemann L, Brenneke B, Andres S, Engstrand L, Meyer TF, Aebischer T, Josenhans C, Suerbaum S.

Infect Immun. 2012 Dec;80(12):4364-73. doi: 10.1128/IAI.00977-12. Epub 2012 Oct 1.

26.

Chronic exposure to the cytolethal distending toxins of Gram-negative bacteria promotes genomic instability and altered DNA damage response.

Guidi R, Guerra L, Levi L, Stenerlöw B, Fox JG, Josenhans C, Masucci MG, Frisan T.

Cell Microbiol. 2013 Jan;15(1):98-113. doi: 10.1111/cmi.12034. Epub 2012 Nov 1.

27.

Genome sequence of Helicobacter pylori hpEurope strain N6.

Behrens W, Bönig T, Suerbaum S, Josenhans C.

J Bacteriol. 2012 Jul;194(14):3725-6. doi: 10.1128/JB.00386-12.

28.

Closely related Campylobacter jejuni strains from different sources reveal a generalist rather than a specialist lifestyle.

Gripp E, Hlahla D, Didelot X, Kops F, Maurischat S, Tedin K, Alter T, Ellerbroek L, Schreiber K, Schomburg D, Janssen T, Bartholomäus P, Hofreuter D, Woltemate S, Uhr M, Brenneke B, Grüning P, Gerlach G, Wieler L, Suerbaum S, Josenhans C.

BMC Genomics. 2011 Nov 28;12:584. doi: 10.1186/1471-2164-12-584.

29.

A Nod toward understanding Crohn's pathology.

Hornef M, Josenhans C.

Nat Med. 2011 Jul 7;17(7):785-7. doi: 10.1038/nm0711-785. No abstract available.

PMID:
21738156
30.

Helicobacter pylori genome evolution during human infection.

Kennemann L, Didelot X, Aebischer T, Kuhn S, Drescher B, Droege M, Reinhardt R, Correa P, Meyer TF, Josenhans C, Falush D, Suerbaum S.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5033-8. doi: 10.1073/pnas.1018444108. Epub 2011 Mar 7.

31.

Helicobacter pylori affects the cellular deubiquitinase USP7 and ubiquitin-regulated components TRAF6 and the tumour suppressor p53.

Coombs N, Sompallae R, Olbermann P, Gastaldello S, Göppel D, Masucci MG, Josenhans C.

Int J Med Microbiol. 2011 Mar;301(3):213-24. doi: 10.1016/j.ijmm.2010.09.004. Epub 2010 Dec 4.

PMID:
21131231
32.

A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island.

Olbermann P, Josenhans C, Moodley Y, Uhr M, Stamer C, Vauterin M, Suerbaum S, Achtman M, Linz B.

PLoS Genet. 2010 Aug 19;6(8):e1001069. doi: 10.1371/journal.pgen.1001069.

33.

The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models.

Nell S, Suerbaum S, Josenhans C.

Nat Rev Microbiol. 2010 Aug;8(8):564-77. doi: 10.1038/nrmicro2403. Epub 2010 Jul 12. Review.

PMID:
20622892
34.

Bacterial energy taxis: a global strategy?

Schweinitzer T, Josenhans C.

Arch Microbiol. 2010 Jul;192(7):507-20. doi: 10.1007/s00203-010-0575-7. Epub 2010 Apr 22. Review.

35.

Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen.

O'Toole PW, Snelling WJ, Canchaya C, Forde BM, Hardie KR, Josenhans C, Graham RLj, McMullan G, Parkhill J, Belda E, Bentley SD.

BMC Genomics. 2010 Mar 10;11:164. doi: 10.1186/1471-2164-11-164.

36.

Myc is required for activation of the ATM-dependent checkpoints in response to DNA damage.

Guerra L, Albihn A, Tronnersjö S, Yan Q, Guidi R, Stenerlöw B, Sterzenbach T, Josenhans C, Fox JG, Schauer DB, Thelestam M, Larsson LG, Henriksson M, Frisan T.

PLoS One. 2010 Jan 27;5(1):e8924. doi: 10.1371/journal.pone.0008924.

37.

The Helicobacter pylori anti-sigma factor FlgM is predominantly cytoplasmic and cooperates with the flagellar basal body protein FlhA.

Rust M, Borchert S, Niehus E, Kuehne SA, Gripp E, Bajceta A, McMurry JL, Suerbaum S, Hughes KT, Josenhans C.

J Bacteriol. 2009 Aug;191(15):4824-34. doi: 10.1128/JB.00018-09. Epub 2009 May 22.

38.

Helicobacter pylori lipopolysaccharide interacts with TFF1 in a pH-dependent manner.

Reeves EP, Ali T, Leonard P, Hearty S, O'Kennedy R, May FE, Westley BR, Josenhans C, Rust M, Suerbaum S, Smith A, Drumm B, Clyne M.

Gastroenterology. 2008 Dec;135(6):2043-54, 2054.e1-2. doi: 10.1053/j.gastro.2008.08.049. Epub 2008 Sep 3.

PMID:
18848942
39.

Role of the Helicobacter hepaticus flagellar sigma factor FliA in gene regulation and murine colonization.

Sterzenbach T, Bartonickova L, Behrens W, Brenneke B, Schulze J, Kops F, Chin EY, Katzowitsch E, Schauer DB, Fox JG, Suerbaum S, Josenhans C.

J Bacteriol. 2008 Oct;190(19):6398-408. doi: 10.1128/JB.00626-08. Epub 2008 Aug 8.

40.

Helicobacter hepaticus HHGI1 is a pathogenicity island associated with typhlocolitis in B6.129-IL10 tm1Cgn mice.

Ge Z, Sterzenbach T, Whary MT, Rickman BH, Rogers AB, Shen Z, Taylor NS, Schauer DB, Josenhans C, Suerbaum S, Fox JG.

Microbes Infect. 2008 Jun;10(7):726-33. doi: 10.1016/j.micinf.2008.03.011. Epub 2008 Apr 4.

41.

Functional characterization and mutagenesis of the proposed behavioral sensor TlpD of Helicobacter pylori.

Schweinitzer T, Mizote T, Ishikawa N, Dudnik A, Inatsu S, Schreiber S, Suerbaum S, Aizawa S, Josenhans C.

J Bacteriol. 2008 May;190(9):3244-55. doi: 10.1128/JB.01940-07. Epub 2008 Feb 1.

42.

Helicobacter pylori evolution and phenotypic diversification in a changing host.

Suerbaum S, Josenhans C.

Nat Rev Microbiol. 2007 Jun;5(6):441-52. Review.

PMID:
17505524
43.

Pathogenomics of helicobacter.

Josenhans C, Beier D, Linz B, Meyer TF, Suerbaum S.

Int J Med Microbiol. 2007 Nov;297(7-8):589-600. Epub 2007 Apr 9. Review.

PMID:
17416549
44.

Inhibitory effect of enterohepatic Helicobacter hepaticus on innate immune responses of mouse intestinal epithelial cells.

Sterzenbach T, Lee SK, Brenneke B, von Goetz F, Schauer DB, Fox JG, Suerbaum S, Josenhans C.

Infect Immun. 2007 Jun;75(6):2717-28. Epub 2007 Mar 19.

45.

Flagellar and global gene regulation in Helicobacter pylori modulated by changes in DNA supercoiling.

Ye F, Brauer T, Niehus E, Drlica K, Josenhans C, Suerbaum S.

Int J Med Microbiol. 2007 Apr;297(2):65-81. Epub 2007 Feb 1.

PMID:
17276136
46.

Characterization of the pilin ortholog of the Helicobacter pylori type IV cag pathogenicity apparatus, a surface-associated protein expressed during infection.

Andrzejewska J, Lee SK, Olbermann P, Lotzing N, Katzowitsch E, Linz B, Achtman M, Kado CI, Suerbaum S, Josenhans C.

J Bacteriol. 2006 Aug;188(16):5865-77.

47.

Genomic changes during chronic Helicobacter pylori infection.

Kraft C, Stack A, Josenhans C, Niehus E, Dietrich G, Correa P, Fox JG, Falush D, Suerbaum S.

J Bacteriol. 2006 Jan;188(1):249-54.

48.

Gastric antibacterial efficiency is different for pepsin A and C.

Schreiber S, Bücker R, Groll C, Azevedo-Vethacke M, Scheid P, Gatermann S, Josenhans C, Suerbaum S.

Arch Microbiol. 2006 Jan;184(5):335-40. Epub 2005 Dec 7.

PMID:
16333616
49.

Different Helicobacter hepaticus strains with variable genomic content induce various degrees of hepatitis.

Boutin SR, Shen Z, Rogers AB, Feng Y, Ge Z, Xu S, Sterzenbach T, Josenhans C, Schauer DB, Suerbaum S, Fox JG.

Infect Immun. 2005 Dec;73(12):8449-52.

50.

Helicobacter pylori and the innate immune system.

Lee SK, Josenhans C.

Int J Med Microbiol. 2005 Sep;295(5):325-34. Review.

PMID:
16173499

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