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Imlifidase Inhibits HLA Antibody-Mediated NK Cell Activation and Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) In Vitro.

Ge S, Chu M, Choi J, Louie S, Vo A, Jordan SC, Toyoda M.

Transplantation. 2019 Oct 21. doi: 10.1097/TP.0000000000003023. [Epub ahead of print]


Outcomes of Conversion from Calcineurin Inhibitor to Belatacept-Based Immunosuppression in HLA Sensitized Kidney Transplant Recipients.

Sethi S, Najjar R, Peng A, Choi J, Lim K, Vo A, Jordan SC, Huang E.

Transplantation. 2019 Sep 19. doi: 10.1097/TP.0000000000002976. [Epub ahead of print]


Implications of Fc Neonatal Receptor (FcRn) Manipulations for Transplant Immunotherapeutics.

Jordan SC, Ammerman N, Vo A.

Transplantation. 2019 Aug 5. doi: 10.1097/TP.0000000000002912. [Epub ahead of print]


Impact of Tocilizumab (Anti-IL-6R) Treatment on Immunoglobulins and Anti-HLA Antibodies in Kidney Transplant Patients with Chronic Antibody-Mediated Rejection.

Shin BH, Everly MJ, Zhang H, Choi J, Vo A, Zhang X, Huang E, Jordan SC, Toyoda M.

Transplantation. 2019 Aug 1. doi: 10.1097/TP.0000000000002895. [Epub ahead of print]


Safety, pharmacokinetics, and pharmacodynamic activity of obinutuzumab, a type 2 anti-CD20 monoclonal antibody for the desensitization of candidates for renal transplant.

Redfield RR, Jordan SC, Busque S, Vincenti F, Woodle ES, Desai N, Reed EF, Tremblay S, Zachary AA, Vo AA, Formica R, Schindler T, Tran H, Looney C, Jamois C, Green C, Morimoto A, Rajwanshi R, Schroeder A, Cascino MD, Brunetta P, Borie D.

Am J Transplant. 2019 Nov;19(11):3035-3045. doi: 10.1111/ajt.15514. Epub 2019 Jul 23.


Clinical and Public Policy Implications of Pre-Formed DSA and Transplant Outcomes.

Huang E, Jordan SC.

Clin J Am Soc Nephrol. 2019 Jul 5;14(7):972-974. doi: 10.2215/CJN.05950519. Epub 2019 Jun 18. No abstract available.


Update on C1 Esterase Inhibitor in Human Solid Organ Transplantation.

Berger M, Lefaucheur C, Jordan SC.

Transplantation. 2019 Sep;103(9):1763-1775. doi: 10.1097/TP.0000000000002717.


Allocation of the Highest Quality Kidneys and Transplant Outcomes Under the New Kidney Allocation System.

Sethi S, Najjar R, Peng A, Mirocha J, Vo A, Bunnapradist S, Jordan SC, Huang E.

Am J Kidney Dis. 2019 May;73(5):605-614. doi: 10.1053/j.ajkd.2018.12.036. Epub 2019 Mar 28.


Clinical Relevance of PostTransplant Donor Specific Antibodies (DSAs) in Patients Receiving Desensitization for HLA Incompatible Kidney Transplantation.

Vo AA, Aubert O, Haas M, Huang E, Zhang X, Choi J, Peng A, Najjar R, Sethi S, Ammerman N, Lim K, Jordan SC.

Transplantation. 2019 Mar 6. doi: 10.1097/TP.0000000000002691. [Epub ahead of print]


Immune response to non-HLA antigens and renal allograft loss.

Jordan SC.

Lancet. 2019 Mar 2;393(10174):854-856. doi: 10.1016/S0140-6736(18)33186-6. Epub 2019 Feb 14. No abstract available.


Early clinical experience using donor-derived cell-free DNA to detect rejection in kidney transplant recipients.

Huang E, Sethi S, Peng A, Najjar R, Mirocha J, Haas M, Vo A, Jordan SC.

Am J Transplant. 2019 Jun;19(6):1663-1670. doi: 10.1111/ajt.15289. Epub 2019 Mar 29.


Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Failure in a Liver Transplant Patient: A Case Report.

Kim IK, Nissen NN, Steggerda J, Gereboff A, Sharma V, Kariger R, Klein AS, Annamalai A, Todo T, Nurok M, Dong E, Friedman O, Jordan SC, Ramzy D.

Transplant Proc. 2018 Dec;50(10):4038-4041. doi: 10.1016/j.transproceed.2018.07.013. Epub 2018 Jul 7.


Novel Therapeutic Approaches to Allosensitization and Antibody-mediated Rejection.

Jordan SC, Ammerman N, Choi J, Huang E, Peng A, Sethi S, Najjar R, Toyoda M, Lim K, Louie S, Vo A.

Transplantation. 2019 Feb;103(2):262-272. doi: 10.1097/TP.0000000000002462. Review.


Donor-derived Cell-free DNA Identifies Antibody-mediated Rejection in Donor Specific Antibody Positive Kidney Transplant Recipients.

Jordan SC, Bunnapradist S, Bromberg JS, Langone AJ, Hiller D, Yee JP, Sninsky JJ, Woodward RN, Matas AJ.

Transplant Direct. 2018 Aug 20;4(9):e379. doi: 10.1097/TXD.0000000000000821. eCollection 2018 Sep.


Prognostic tools to assess candidacy for and efficacy of antibody-removal therapy.

Pinelli DF, Zachary AA, Friedewald JJ, Gjertson DW, Evans MA, Chatroop EN, Leffell MS, Vo AA, Jordan SC, Montgomery RA, Tambur AR.

Am J Transplant. 2019 Feb;19(2):381-390. doi: 10.1111/ajt.15007. Epub 2018 Aug 23.


A phase I/II, double-blind, placebo-controlled study assessing safety and efficacy of C1 esterase inhibitor for prevention of delayed graft function in deceased donor kidney transplant recipients.

Jordan SC, Choi J, Aubert O, Haas M, Loupy A, Huang E, Peng A, Kim I, Louie S, Ammerman N, Najjar R, Puliyanda D, Vo A.

Am J Transplant. 2018 Dec;18(12):2955-2964. doi: 10.1111/ajt.14767. Epub 2018 May 14.


IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation.

Jordan SC, Lorant T, Choi J.

N Engl J Med. 2017 Oct 26;377(17):1693-4. doi: 10.1056/NEJMc1711335. No abstract available.


Risk factors for the development of antibody-mediated rejection in highly sensitized pediatric kidney transplant recipients.

Kim IK, Choi J, Vo A, Kang A, Steggerda J, Louie S, Haas M, Mirocha J, Cohen JL, Pizzo H, Kamil ES, Jordan SC, Puliyanda D.

Pediatr Transplant. 2017 Dec;21(8). doi: 10.1111/petr.13042. Epub 2017 Sep 19.


Hospital readmissions following HLA-incompatible live donor kidney transplantation: A multi-center study.

Orandi BJ, Luo X, King EA, Garonzik-Wang JM, Bae S, Montgomery RA, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Osama Gaber A, Segev DL.

Am J Transplant. 2018 Mar;18(3):650-658. doi: 10.1111/ajt.14472. Epub 2017 Sep 23.


IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation.

Jordan SC, Lorant T, Choi J, Kjellman C, Winstedt L, Bengtsson M, Zhang X, Eich T, Toyoda M, Eriksson BM, Ge S, Peng A, Järnum S, Wood KJ, Lundgren T, Wennberg L, Bäckman L, Larsson E, Villicana R, Kahwaji J, Louie S, Kang A, Haas M, Nast C, Vo A, Tufveson G.

N Engl J Med. 2017 Aug 3;377(5):442-453. doi: 10.1056/NEJMoa1612567. Erratum in: N Engl J Med. 2017 Oct 26;377(17 ):1700.


Outcomes of Highly Sensitized Patients Undergoing Simultaneous Liver and Kidney Transplantation: A Single-Center Experience With Desensitization.

Steggerda JA, Kang A, Pan SH, Sundaram V, Nissen NN, Klein AS, Todo T, Annamalai A, Vo A, Jordan SC, Kim IK.

Transplant Proc. 2017 Jul - Aug;49(6):1394-1401. doi: 10.1016/j.transproceed.2017.01.079.


The Incremental Cost of Incompatible Living Donor Kidney Transplantation: A National Cohort Analysis.

Axelrod D, Lentine KL, Schnitzler MA, Luo X, Xiao H, Orandi BJ, Massie A, Garonzik-Wang J, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Osama Gaber A, Montgomery RA, Segev DL.

Am J Transplant. 2017 Dec;17(12):3123-3130. doi: 10.1111/ajt.14392. Epub 2017 Jul 21.


Plasma Exosomes From HLA-Sensitized Kidney Transplant Recipients Contain mRNA Transcripts Which Predict Development of Antibody-Mediated Rejection.

Zhang H, Huang E, Kahwaji J, Nast CC, Li P, Mirocha J, Thomas DL, Ge S, Vo AA, Jordan SC, Toyoda M.

Transplantation. 2017 Oct;101(10):2419-2428. doi: 10.1097/TP.0000000000001834.


Tocilizumab (Anti-IL-6R) Suppressed TNFα Production by Human Monocytes in an In Vitro Model of Anti-HLA Antibody-Induced Antibody-Dependent Cellular Cytotoxicity.

Shin BH, Ge S, Mirocha J, Jordan SC, Toyoda M.

Transplant Direct. 2017 Feb 16;3(3):e139. doi: 10.1097/TXD.0000000000000653. eCollection 2017 Mar.


Cell-Free DNA and Active Rejection in Kidney Allografts.

Bloom RD, Bromberg JS, Poggio ED, Bunnapradist S, Langone AJ, Sood P, Matas AJ, Mehta S, Mannon RB, Sharfuddin A, Fischbach B, Narayanan M, Jordan SC, Cohen D, Weir MR, Hiller D, Prasad P, Woodward RN, Grskovic M, Sninsky JJ, Yee JP, Brennan DC; Circulating Donor-Derived Cell-Free DNA in Blood for Diagnosing Active Rejection in Kidney Transplant Recipients (DART) Study Investigators.

J Am Soc Nephrol. 2017 Jul;28(7):2221-2232. doi: 10.1681/ASN.2016091034. Epub 2017 Mar 9.


Impact of Desensitization on Antiviral Immunity in HLA-Sensitized Kidney Transplant Recipients.

Toyoda M, Shin BH, Ge S, Mirocha J, Thomas D, Chu M, Rodriguez E, Chao C, Petrosyan A, Galera OA, Vo A, Choi J, Peng A, Kahwaji J, Jordan SC.

J Immunol Res. 2017;2017:5672523. doi: 10.1155/2017/5672523. Epub 2017 Feb 6.


Clinical Trials for Immunosuppression in Transplantation: The Case for Reform and Change in Direction.

OʼConnell PJ, Kuypers DR, Mannon RB, Abecassis M, Chadban SJ, Gill JS, Murphy B, Nickerson PW, Schold JD, Stock PG, Seron D, Alloway RR, Bromberg JS, Budde K, Jordan SC, Legendre C, Lefaucheur C, Sarwall M, Segev DL, Stegall MD, Tullius SG, Wong G, Woodle ES, Ascher N, Morris RE.

Transplantation. 2017 Jul;101(7):1527-1534. doi: 10.1097/TP.0000000000001648.


Assessment of Tocilizumab (Anti-Interleukin-6 Receptor Monoclonal) as a Potential Treatment for Chronic Antibody-Mediated Rejection and Transplant Glomerulopathy in HLA-Sensitized Renal Allograft Recipients.

Choi J, Aubert O, Vo A, Loupy A, Haas M, Puliyanda D, Kim I, Louie S, Kang A, Peng A, Kahwaji J, Reinsmoen N, Toyoda M, Jordan SC.

Am J Transplant. 2017 Sep;17(9):2381-2389. doi: 10.1111/ajt.14228. Epub 2017 Mar 10.


Desensitization: Overcoming the Immunologic Barriers to Transplantation.

Sethi S, Choi J, Toyoda M, Vo A, Peng A, Jordan SC.

J Immunol Res. 2017;2017:6804678. doi: 10.1155/2017/6804678. Epub 2017 Jan 3. Review.


Differences in pathologic features and graft outcomes in antibody-mediated rejection of renal allografts due to persistent/recurrent versus de novo donor-specific antibodies.

Haas M, Mirocha J, Reinsmoen NL, Vo AA, Choi J, Kahwaji JM, Peng A, Villicana R, Jordan SC.

Kidney Int. 2017 Mar;91(3):729-737. doi: 10.1016/j.kint.2016.10.040. Epub 2017 Jan 16.


Update on the use of immunoglobulin in human disease: A review of evidence.

Perez EE, Orange JS, Bonilla F, Chinen J, Chinn IK, Dorsey M, El-Gamal Y, Harville TO, Hossny E, Mazer B, Nelson R, Secord E, Jordan SC, Stiehm ER, Vo AA, Ballow M.

J Allergy Clin Immunol. 2017 Mar;139(3S):S1-S46. doi: 10.1016/j.jaci.2016.09.023. Epub 2016 Dec 29. Review.


Cytomegalovirus Immunity After Alemtuzumab Induction in Desensitized Kidney Transplant Patients.

Ge S, Karasyov A, Sinha A, Petrosyan A, Lovato D, Thomas DL, Vo A, Jordan SC, Toyoda M.

Transplantation. 2017 Jul;101(7):1720-1726. doi: 10.1097/TP.0000000000001573.


Six-year outcomes in broadly HLA-sensitized living donor transplant recipients desensitized with intravenous immunoglobulin and rituximab.

Kahwaji J, Jordan SC, Najjar R, Wongsaroj P, Choi J, Peng A, Villicana R, Vo A.

Transpl Int. 2016 Dec;29(12):1276-1285. doi: 10.1111/tri.12832. Epub 2016 Oct 24.


Novel role of Vav1-Rac1 pathway in actin cytoskeleton regulation in interleukin-13-induced minimal change-like nephropathy.

Chan CY, Ng KH, Chen J, Lu J, Lee CG, Tan PH, Jordan SC, He HY, Yap HK.

Clin Sci (Lond). 2016 Dec 1;130(24):2317-2327. doi: 10.1042/CS20160312. Epub 2016 Oct 5.


Interleukin-6, A Cytokine Critical to Mediation of Inflammation, Autoimmunity and Allograft Rejection: Therapeutic Implications of IL-6 Receptor Blockade.

Jordan SC, Choi J, Kim I, Wu G, Toyoda M, Shin B, Vo A.

Transplantation. 2017 Jan;101(1):32-44. doi: 10.1097/TP.0000000000001452. Review.


Immunological characterization of de novo and recall alloantibody suppression by CTLA4Ig in a mouse model of allosensitization.

Kim I, Wu G, Chai NN, Klein AS, Jordan SC.

Transpl Immunol. 2016 Sep;38:84-92. doi: 10.1016/j.trim.2016.08.001. Epub 2016 Aug 6.


Safety and Efficacy of Alemtuzumab Induction in Highly Sensitized Pediatric Renal Transplant Recipients.

Kim IK, Choi J, Vo AA, Kang A, Patel M, Toyoda M, Mirocha J, Kamil ES, Cohen JL, Louie S, Galera O, Jordan SC, Puliyanda DP.

Transplantation. 2017 Apr;101(4):883-889. doi: 10.1097/TP.0000000000001416.


T Lymphocyte Activation Markers as Predictors of Responsiveness to Rituximab among Patients with FSGS.

Chan CY, Liu ID, Resontoc LP, Ng KH, Chan YH, Lau PY, Than M, Jordan SC, Lam KP, Yeo WS, Yap HK.

Clin J Am Soc Nephrol. 2016 Aug 8;11(8):1360-8. doi: 10.2215/CJN.11941115. Epub 2016 Jun 7.


Risk factors associated with the development of histocompatibility leukocyte antigen sensitization.

Jordan SC, Choi J, Kim I, Vo A, Peng A, Kahwaji J.

Curr Opin Organ Transplant. 2016 Aug;21(4):447-52. doi: 10.1097/MOT.0000000000000336. Review.


Complement Inhibition for Prevention and Treatment of Antibody-Mediated Rejection in Renal Allograft Recipients.

Jordan SC, Choi J, Kahwaji J, Vo A.

Transplant Proc. 2016 Apr;48(3):806-8. doi: 10.1016/j.transproceed.2015.11.028.


Progress in Desensitization of the Highly HLA Sensitized Patient.

Jordan SC, Choi J, Kahwaji J, Vo A.

Transplant Proc. 2016 Apr;48(3):802-5. doi: 10.1016/j.transproceed.2015.11.027.


Survival Benefit with Kidney Transplants from HLA-Incompatible Live Donors.

Orandi BJ, Luo X, Massie AB, Garonzik-Wang JM, Lonze BE, Ahmed R, Van Arendonk KJ, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Gaber AO, Montgomery RA, Segev DL.

N Engl J Med. 2016 Mar 10;374(10):940-50. doi: 10.1056/NEJMoa1508380.


Liver Transplantation in a Patient With CD40 Ligand Deficiency and Hyper-IgM Syndrome: Clinical and Immunological Assessments.

Tseng M, Ge S, Roberts R, Kuo C, Choi J, Nissen NN, Kim I, Chu M, Shin B, Toyoda M, Jordan SC.

Am J Transplant. 2016 May;16(5):1626-1632. doi: 10.1111/ajt.13580. Epub 2016 Jan 13.


Potential Roles for C1 Inhibitor in Transplantation.

Berger M, Baldwin WM 3rd, Jordan SC.

Transplantation. 2016 Jul;100(7):1415-24. doi: 10.1097/TP.0000000000000995. Review.


Combined Lung-Kidney Transplantation: An Analysis of the UNOS/OPTN Database.

Reich HJ, Chan JL, Czer LS, Mirocha J, Annamalai AA, Cheng W, Jordan SC, Chaux G, Ramzy D.

Am Surg. 2015 Oct;81(10):1047-52.


JC polyomavirus viremia and progressive multifocal leukoencephalopathy in human leukocyte antigen-sensitized kidney transplant recipients desensitized with intravenous immunoglobulin and rituximab.

Toyoda M, Thomas D, Ahn G, Kahwaji J, Mirocha J, Chu M, Vo A, Suviolahti E, Ge S, Jordan SC.

Transpl Infect Dis. 2015 Dec;17(6):838-47. doi: 10.1111/tid.12465.


Donor-Specific HLA Antibody IgG Subclasses Are Associated with Phenotypes of Antibody-Mediated Rejection in Sensitized Renal Allograft Recipients.

Jordan SC.

J Am Soc Nephrol. 2016 Jan;27(1):6-8. doi: 10.1681/ASN.2015060608. Epub 2015 Aug 20. No abstract available.


Modern approaches to incompatible kidney transplantation.

Wongsaroj P, Kahwaji J, Vo A, Jordan SC.

World J Nephrol. 2015 Jul 6;4(3):354-62. doi: 10.5527/wjn.v4.i3.354. Review.


Genetic Interactions Between TRPC6 and NPHS1 Variants Affect Posttransplant Risk of Recurrent Focal Segmental Glomerulosclerosis.

Sun ZJ, Ng KH, Liao P, Zhang Y, Ng JL, Liu ID, Tan PH, Chong SS, Chan YH, Liu J, Davila S, Heng CK, Jordan SC, Soong TW, Yap HK.

Am J Transplant. 2015 Dec;15(12):3229-38. doi: 10.1111/ajt.13378. Epub 2015 Jul 3.

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