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Items: 1 to 50 of 120

1.

3D bioprinting of functional human skin: production and in vivo analysis.

Cubo N, Garcia M, Del Cañizo JF, Velasco D, Jorcano JL.

Biofabrication. 2016 Dec 5;9(1):015006.

PMID:
27917823
2.

Differential Features between Chronic Skin Inflammatory Diseases Revealed in Skin-Humanized Psoriasis and Atopic Dermatitis Mouse Models.

Carretero M, Guerrero-Aspizua S, Illera N, Galvez V, Navarro M, García-García F, Dopazo J, Jorcano JL, Larcher F, del Rio M.

J Invest Dermatol. 2016 Jan;136(1):136-45. doi: 10.1038/JID.2015.362.

3.

Identification of two rare and novel large deletions in ITGB4 gene causing epidermolysis bullosa with pyloric atresia.

Mencía Á, García M, García E, Llames S, Charlesworth A, de Lucas R, Vicente A, Trujillo-Tiebas MJ, Coto P, Costa M, Vera Á, López-Pestaña A, Murillas R, Meneguzzi G, Jorcano JL, Conti CJ, Escámez Toledano MJ, del Río Nechaevsky M.

Exp Dermatol. 2016 Apr;25(4):269-74. doi: 10.1111/exd.12938. Epub 2016 Feb 13.

PMID:
26739954
4.

Differential Features Between Chronic Skin Inflammatory Diseases Revealed in Skin-Humanized Psoriasis and Atopic Dermatitis Mouse Models.

Carretero M, Guerrero-Aspizua S, Illera N, Galvez V, Navarro M, García-García F, Dopazo J, Jorcano JL, Larcher F, Del Rio M.

J Invest Dermatol. 2015 Sep 23. doi: 10.1038/jid.2015.362. [Epub ahead of print]

PMID:
26398345
5.

Tumor initiation by skin Ha-ras-ment.

Guerrero-Aspizua S, Larcher F, Del Río M, Jorcano JL, Conti CJ.

Exp Dermatol. 2015 Apr;24(4):252-3. doi: 10.1111/exd.12640. No abstract available.

PMID:
25607847
6.

Remote diffuse reflectance spectroscopy sensor for tissue engineering monitoring based on blind signal separation.

Martín-Mateos P, Crespo-Garcia S, Ruiz-Llata M, Lopez-Fernandez JR, Jorcano JL, Del Rio M, Larcher F, Acedo P.

Biomed Opt Express. 2014 Aug 28;5(9):3231-7. doi: 10.1364/BOE.5.003231. eCollection 2014 Sep 1.

7.

The regenerative potential of fibroblasts in a new diabetes-induced delayed humanised wound healing model.

Martínez-Santamaría L, Conti CJ, Llames S, García E, Retamosa L, Holguín A, Illera N, Duarte B, Camblor L, Llaneza JM, Jorcano JL, Larcher F, Meana Á, Escámez MJ, Del Río M.

Exp Dermatol. 2013 Mar;22(3):195-201. doi: 10.1111/exd.12097.

PMID:
23489422
8.

Increased IKKα expression in the basal layer of the epidermis of transgenic mice enhances the malignant potential of skin tumors.

Alameda JP, Moreno-Maldonado R, Fernández-Aceñero MJ, Navarro M, Page A, Jorcano JL, Bravo A, Ramírez Á, Casanova ML.

PLoS One. 2011;6(7):e21984. doi: 10.1371/journal.pone.0021984. Epub 2011 Jul 6.

9.

Development of a bioengineered skin-humanized mouse model for psoriasis: dissecting epidermal-lymphocyte interacting pathways.

Guerrero-Aspizua S, García M, Murillas R, Retamosa L, Illera N, Duarte B, Holguín A, Puig S, Hernández MI, Meana A, Jorcano JL, Larcher F, Carretero M, Del Río M.

Am J Pathol. 2010 Dec;177(6):3112-24. doi: 10.2353/ajpath.2010.100078. Epub 2010 Oct 22.

10.

An inactivating CYLD mutation promotes skin tumor progression by conferring enhanced proliferative, survival and angiogenic properties to epidermal cancer cells.

Alameda JP, Moreno-Maldonado R, Navarro M, Bravo A, Ramírez A, Page A, Jorcano JL, Fernández-Aceñero MJ, Casanova ML.

Oncogene. 2010 Dec 16;29(50):6522-32. doi: 10.1038/onc.2010.378. Epub 2010 Sep 13.

PMID:
20838385
11.

In vivo assessment of acute UVB responses in normal and Xeroderma Pigmentosum (XP-C) skin-humanized mouse models.

García M, Llames S, García E, Meana A, Cuadrado N, Recasens M, Puig S, Nagore E, Illera N, Jorcano JL, Del Rio M, Larcher F.

Am J Pathol. 2010 Aug;177(2):865-72. doi: 10.2353/ajpath.2010.091096. Epub 2010 Jun 17.

12.

IKKbeta leads to an inflammatory skin disease resembling interface dermatitis.

Page A, Navarro M, Garín M, Pérez P, Casanova ML, Moreno R, Jorcano JL, Cascallana JL, Bravo A, Ramírez A.

J Invest Dermatol. 2010 Jun;130(6):1598-610. doi: 10.1038/jid.2010.28. Epub 2010 Mar 4.

13.

The first COL7A1 mutation survey in a large Spanish dystrophic epidermolysis bullosa cohort: c.6527insC disclosed as an unusually recurrent mutation.

Escámez MJ, García M, Cuadrado-Corrales N, Llames SG, Charlesworth A, De Luca N, Illera N, Sánchez-Jimeno C, Holguín A, Duarte B, Trujillo-Tiebas MJ, Vicario JL, Santiago JL, Hernández-Martín A, Torrelo A, Castiglia D, Ayuso C, Larcher F, Jorcano JL, Meana A, Meneguzzi G, Zambruno G, Del Rio M.

Br J Dermatol. 2010 Jul;163(1):155-61. doi: 10.1111/j.1365-2133.2010.09713.x. Epub 2010 Feb 22.

PMID:
20184583
14.

Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair.

Antsiferova M, Klatte JE, Bodó E, Paus R, Jorcano JL, Matzuk MM, Werner S, Kögel H.

Lab Invest. 2009 Feb;89(2):131-41. doi: 10.1038/labinvest.2008.120. Epub 2008 Dec 15.

15.

IKKalpha enhances human keratinocyte differentiation and determines the histological variant of epidermal squamous cell carcinomas.

Moreno-Maldonado R, Ramírez A, Navarro M, Fernández-Aceñero MJ, Villanueva C, Page A, Jorcano JL, Bravo A, Llanos Casanova M.

Cell Cycle. 2008 Jul 1;7(13):2021-9. Epub 2008 Apr 11.

PMID:
18604171
16.

Assessment of optimal virus-mediated growth factor gene delivery for human cutaneous wound healing enhancement.

Escámez MJ, Carretero M, García M, Martínez-Santamaría L, Mirones I, Duarte B, Holguín A, García E, García V, Meana A, Jorcano JL, Larcher F, Del Río M.

J Invest Dermatol. 2008 Jun;128(6):1565-75. doi: 10.1038/sj.jid.5701217. Epub 2008 Jan 10.

17.

In vitro and in vivo wound healing-promoting activities of human cathelicidin LL-37.

Carretero M, Escámez MJ, García M, Duarte B, Holguín A, Retamosa L, Jorcano JL, Río MD, Larcher F.

J Invest Dermatol. 2008 Jan;128(1):223-36. Epub 2007 Sep 13.

18.

Modeling normal and pathological processes through skin tissue engineering.

Garcia M, Escamez MJ, Carretero M, Mirones I, Martinez-Santamaria L, Navarro M, Jorcano JL, Meana A, Del Rio M, Larcher F.

Mol Carcinog. 2007 Aug;46(8):741-5. Review.

PMID:
17610222
19.

Long-term engraftment of single genetically modified human epidermal holoclones enables safety pre-assessment of cutaneous gene therapy.

Larcher F, Dellambra E, Rico L, Bondanza S, Murillas R, Cattoglio C, Mavilio F, Jorcano JL, Zambruno G, Del Rio M.

Mol Ther. 2007 Sep;15(9):1670-6. Epub 2007 Jun 19.

20.

Epidermal hyperplasia and papillomatosis in mice with a keratinocyte-restricted deletion of csk.

Honda K, Sakaguchi T, Sakai K, Schmedt C, Ramirez A, Jorcano JL, Tarakhovsky A, Kamisoyama H, Sakai T.

Carcinogenesis. 2007 Oct;28(10):2074-81. Epub 2007 May 10.

PMID:
17494055
21.

The ends of a conundrum?

Paramio JM, Santos M, Jorcano JL.

J Cell Sci. 2007 Apr 1;120(Pt 7):1145-7; author reply 1147-8. No abstract available.

22.

Skin gene therapy for acquired and inherited disorders.

Carretero M, Escámez MJ, Prada F, Mirones I, García M, Holguín A, Duarte B, Podhajcer O, Jorcano JL, Larcher F, Del Río M.

Histol Histopathol. 2006 Nov;21(11):1233-47. doi: 10.14670/HH-21.1233. Review.

PMID:
16874666
23.

Clinical results of an autologous engineered skin.

Llames S, García E, García V, del Río M, Larcher F, Jorcano JL, López E, Holguín P, Miralles F, Otero J, Meana A.

Cell Tissue Bank. 2006;7(1):47-53.

PMID:
16511664
24.

Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK.

Essayem S, Kovacic-Milivojevic B, Baumbusch C, McDonagh S, Dolganov G, Howerton K, Larocque N, Mauro T, Ramirez A, Ramos DM, Fisher SJ, Jorcano JL, Beggs HE, Reichardt LF, Ilic D.

Oncogene. 2006 Feb 16;25(7):1081-9.

25.

Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis.

Sterneck E, Zhu S, Ramirez A, Jorcano JL, Smart RC.

Oncogene. 2006 Feb 23;25(8):1272-1276. doi: 10.1038/sj.onc.1209144.

26.

Targeted overexpression of leptin to keratinocytes in transgenic mice results in lack of skin phenotype but induction of early leptin resistance.

Rico L, Del Rio M, Bravo A, Ramirez A, Jorcano JL, Page MA, Larcher F.

Endocrinology. 2005 Oct;146(10):4167-76. Epub 2005 Jun 30.

PMID:
15994350
27.

Ectoderm-targeted overexpression of the glucocorticoid receptor induces hypohidrotic ectodermal dysplasia.

Cascallana JL, Bravo A, Donet E, Leis H, Lara MF, Paramio JM, Jorcano JL, Pérez P.

Endocrinology. 2005 Jun;146(6):2629-38. Epub 2005 Mar 3.

PMID:
15746257
28.

An in vivo model of wound healing in genetically modified skin-humanized mice.

Escámez MJ, García M, Larcher F, Meana A, Muñoz E, Jorcano JL, Del Río M.

J Invest Dermatol. 2004 Dec;123(6):1182-91.

29.

A cutaneous gene therapy approach to treat infection through keratinocyte-targeted overexpression of antimicrobial peptides.

Carretero M, Del Río M, García M, Escámez MJ, Mirones I, Rivas L, Balague C, Jorcano JL, Larcher F.

FASEB J. 2004 Dec;18(15):1931-3. Epub 2004 Sep 29.

PMID:
15456737
30.

Current approaches and perspectives in human keratinocyte-based gene therapies.

Del Rio M, Gache Y, Jorcano JL, Meneguzzi G, Larcher F.

Gene Ther. 2004 Oct;11 Suppl 1:S57-63. Review.

PMID:
15454958
31.

Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8-expressing transgenic mice.

Casanova ML, Bravo A, Martínez-Palacio J, Fernández-Aceñero MJ, Villanueva C, Larcher F, Conti CJ, Jorcano JL.

FASEB J. 2004 Oct;18(13):1556-8. Epub 2004 Aug 19.

PMID:
15319370
32.

Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor.

Garcia M, Fernandez-Garcia NI, Rivas V, Carretero M, Escamez MJ, Gonzalez-Martin A, Medrano EE, Volpert O, Jorcano JL, Jimenez B, Larcher F, Del Rio M.

Cancer Res. 2004 Aug 15;64(16):5632-42.

33.

Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis.

Ruiz S, Santos M, Segrelles C, Leis H, Jorcano JL, Berns A, Paramio JM, Vooijs M.

Development. 2004 Jun;131(11):2737-48.

34.

A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination.

Ramirez A, Page A, Gandarillas A, Zanet J, Pibre S, Vidal M, Tusell L, Genesca A, Whitaker DA, Melton DW, Jorcano JL.

Genesis. 2004 May;39(1):52-7.

PMID:
15124227
35.

Human plasma as a dermal scaffold for the generation of a completely autologous bioengineered skin.

Llames SG, Del Rio M, Larcher F, García E, García M, Escamez MJ, Jorcano JL, Holguín P, Meana A.

Transplantation. 2004 Feb 15;77(3):350-5.

PMID:
14966407
36.

Glucocorticoid Receptor Counteracts Tumorigenic Activity of Akt in Skin through Interference with the Phosphatidylinositol 3-Kinase Signaling Pathway.

Leis H, Page A, Ramírez A, Bravo A, Segrelles C, Paramio J, Barettino D, Jorcano JL, Pérez P.

Mol Endocrinol. 2004 Feb;18(2):303-11. Epub 2003 Nov 13.

PMID:
14615607
37.

A comparison of targeting performance of oncoretroviral versus lentiviral vectors on human keratinocytes.

Serrano F, Del Rio M, Larcher F, Garcia M, Muñoz E, Escamez MJ, Muñoz M, Meana A, Bernad A, Jorcano JL.

Hum Gene Ther. 2003 Nov 1;14(16):1579-85.

PMID:
14577919
38.

Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues.

Berton TR, Matsumoto T, Page A, Conti CJ, Deng CX, Jorcano JL, Johnson DG.

Oncogene. 2003 Aug 21;22(35):5415-26.

PMID:
12934101
39.

Modulation of the angiogenesis response through Ha-ras control, placenta growth factor, and angiopoietin expression in mouse skin carcinogenesis.

Larcher F, Franco M, Bolontrade M, Rodriguez-Puebla M, Casanova L, Navarro M, Yancopoulos G, Jorcano JL, Conti CJ.

Mol Carcinog. 2003 Jun;37(2):83-90.

PMID:
12766907
40.

Glucocorticoid receptor functions as a potent suppressor of mouse skin carcinogenesis.

Budunova IV, Kowalczyk D, Pérez P, Yao YJ, Jorcano JL, Slaga TJ.

Oncogene. 2003 May 22;22(21):3279-87.

PMID:
12761498
41.

Abnormal epidermal differentiation and impaired epithelial-mesenchymal tissue interactions in mice lacking the retinoblastoma relatives p107 and p130.

Ruiz S, Segrelles C, Bravo A, Santos M, Perez P, Leis H, Jorcano JL, Paramio JM.

Development. 2003 Jun;130(11):2341-53.

42.

Disruption of eyelid and cornea development by targeted overexpression of the glucocorticoid receptor.

Cascallana JL, Bravo A, Page A, Budunova I, Slaga TJ, Jorcano JL, Pérez P.

Int J Dev Biol. 2003 Feb;47(1):59-64.

43.

Impaired NF-kappa B activation and increased production of tumor necrosis factor alpha in transgenic mice expressing keratin K10 in the basal layer of the epidermis.

Santos M, Perez P, Segrelles C, Ruiz S, Jorcano JL, Paramio JM.

J Biol Chem. 2003 Apr 11;278(15):13422-30. Epub 2003 Feb 1.

44.

Inhibition of tumor angiogenesis by cannabinoids.

Blázquez C, Casanova ML, Planas A, Gómez Del Pulgar T, Villanueva C, Fernández-Aceñero MJ, Aragonés J, Huffman JW, Jorcano JL, Guzmán M.

FASEB J. 2003 Mar;17(3):529-31. Epub 2003 Jan 2.

PMID:
12514108
45.

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors.

Casanova ML, Blázquez C, Martínez-Palacio J, Villanueva C, Fernández-Aceñero MJ, Huffman JW, Jorcano JL, Guzmán M.

J Clin Invest. 2003 Jan;111(1):43-50.

46.

Beyond structure: do intermediate filaments modulate cell signalling?

Paramio JM, Jorcano JL.

Bioessays. 2002 Sep;24(9):836-44. Review.

PMID:
12210520
47.

Abnormal cochlea linked to deafness in transgenic mice expressing human cytokeratin K8.

Bartolomé MV, Casanova ML, Carricondo F, del Castillo E, Jorcano JL, Gil-Loyzaga P.

Histol Histopathol. 2002;17(3):827-36. doi: 10.14670/HH-17.827.

PMID:
12168793
48.

Severe abnormalities in the oral mucosa induced by suprabasal expression of epidermal keratin K10 in transgenic mice.

Santos M, Bravo A, López C, Paramio JM, Jorcano JL.

J Biol Chem. 2002 Sep 20;277(38):35371-7. Epub 2002 Jul 15.

49.

A critical role for ras-mediated, epidermal growth factor receptor-dependent angiogenesis in mouse skin carcinogenesis.

Casanova ML, Larcher F, Casanova B, Murillas R, Fernández-Aceñero MJ, Villanueva C, Martínez-Palacio J, Ullrich A, Conti CJ, Jorcano JL.

Cancer Res. 2002 Jun 15;62(12):3402-7.

50.

A preclinical model for the analysis of genetically modified human skin in vivo.

Del Rio M, Larcher F, Serrano F, Meana A, Muñoz M, Garcia M, Muñoz E, Martin C, Bernad A, Jorcano JL.

Hum Gene Ther. 2002 May 20;13(8):959-68.

PMID:
12031128

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