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Items: 1 to 50 of 588

1.

Borrelia burgdorferi hijacks cellular metabolism of immune cells: Consequences for host defense.

Kerstholt M, Netea MG, Joosten LAB.

Ticks Tick Borne Dis. 2020 Feb 3:101386. doi: 10.1016/j.ttbdis.2020.101386. [Epub ahead of print] Review.

2.

Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis.

Dos Santos JC, Leite Quixabeira VB, Teodoro Silva MV, Damen MSMA, Schraa K, Jaeger M, Oosting M, Keating ST, Dorta ML, Alves Pinto S, Bugalho Duarte F, de Araújo Pereira LI, Netea MG, Ribeiro-Dias F, Joosten LAB.

PLoS Negl Trop Dis. 2020 Feb 5;14(2):e0008029. doi: 10.1371/journal.pntd.0008029. [Epub ahead of print]

3.

Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD.

Mirea AM, Stienstra R, Kanneganti TD, Tack CJ, Chavakis T, Toonen EJM, Joosten LAB.

Inflammation. 2020 Jan 30. doi: 10.1007/s10753-020-01190-4. [Epub ahead of print]

PMID:
32002713
4.

Systematic genetic analysis of early-onset gout: ABCG2 is the only associated locus.

Zaidi F, Narang RK, Phipps-Green A, Gamble GG, Tausche AK, So A, Riches P, Andres M, Perez-Ruiz F, Doherty M, Janssen M, Joosten LAB, Jansen TL, Kurreeman F, Torres RJ, McCarthy GM, Miner JN, Stamp LK, Merriman TR, Dalbeth N.

Rheumatology (Oxford). 2020 Jan 30. pii: kez685. doi: 10.1093/rheumatology/kez685. [Epub ahead of print]

PMID:
31998961
5.

Advances in understanding molecular regulation of innate immune memory.

Domínguez-Andrés J, Fanucchi S, Joosten LAB, Mhlanga MM, Netea MG.

Curr Opin Cell Biol. 2020 Jan 25;63:68-75. doi: 10.1016/j.ceb.2019.12.006. [Epub ahead of print] Review.

PMID:
31991317
6.

A joint effort: The interplay between the innate and the adaptive immune system in Lyme arthritis.

Brouwer MAE, van de Schoor FR, Vrijmoeth HD, Netea MG, Joosten LAB.

Immunol Rev. 2020 Jan 13. doi: 10.1111/imr.12837. [Epub ahead of print] Review.

PMID:
31930745
7.

Training the trainable cells of the immune system and beyond.

Kar UK, Joosten LAB.

Nat Immunol. 2020 Feb;21(2):115-119. doi: 10.1038/s41590-019-0583-y. No abstract available.

PMID:
31925389
8.

PET/MRI enables simultaneous in vivo quantification of β-cell mass and function.

Michelotti FC, Bowden G, Küppers A, Joosten L, Maczewsky J, Nischwitz V, Drews G, Maurer A, Gotthardt M, Schmid AM, Pichler BJ.

Theranostics. 2020 Jan 1;10(1):398-410. doi: 10.7150/thno.33410. eCollection 2020.

9.

Safety of switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulant in frail elderly with atrial fibrillation: rationale and design of the FRAIL-AF randomised controlled trial.

Joosten LPT, van Doorn S, Hoes AW, Nierman MC, Wiersma NM, Koek HL, Hemels MEW, Huisman MV, Roes KC, van den Bor RM, Buding WF, Rutten FH, Geersing GJ.

BMJ Open. 2019 Dec 29;9(12):e032488. doi: 10.1136/bmjopen-2019-032488.

10.

Arterial wall inflammation and increased hematopoietic activity in patients with primary aldosteronism.

van der Heijden CDCC, Smeets EMM, Aarntzen EHJG, Noz MP, Monajemi H, Kersten S, Kaffa C, Hoischen A, Deinum J, Joosten LAB, Netea MG, Riksen NP.

J Clin Endocrinol Metab. 2019 Dec 25. pii: dgz306. doi: 10.1210/clinem/dgz306. [Epub ahead of print]

PMID:
31875423
11.

Urate-induced immune programming: Consequences for gouty arthritis and hyperuricemia.

Cabău G, Crișan TO, Klück V, Popp RA, Joosten LAB.

Immunol Rev. 2019 Dec 19. doi: 10.1111/imr.12833. [Epub ahead of print] Review.

PMID:
31853991
12.

Asymptomatic hyperuricaemia: a silent activator of the innate immune system.

Joosten LAB, Crişan TO, Bjornstad P, Johnson RJ.

Nat Rev Rheumatol. 2020 Feb;16(2):75-86. doi: 10.1038/s41584-019-0334-3. Epub 2019 Dec 10. Review.

PMID:
31822862
13.

Leukocyte-Released Mediators in Response to Both Bacterial and Fungal Infections Trigger IFN Pathways, Independent of IL-1 and TNF-α, in Endothelial Cells.

Le KTT, Chu X, Jaeger M, Plantinga JA, Matzaraki V, Withoff S, Joosten LAB, Netea MG, Wijmenga C, Li Y, Moser J, Kumar V.

Front Immunol. 2019 Oct 25;10:2508. doi: 10.3389/fimmu.2019.02508. eCollection 2019.

14.

The role of Toll-like receptor 10 in modulation of trained immunity.

Mourits VP, Arts RJW, Novakovic B, Matzaraki V, de Bree LCJ, Koeken VACM, Moorlag SJCFM, van Puffelen JH, Groh L, van der Heijden CDCC, Keating ST, Netea MG, Oosting M, Joosten LAB.

Immunology. 2020 Mar;159(3):289-297. doi: 10.1111/imm.13145. Epub 2019 Nov 26.

PMID:
31671203
15.

Sixteen-Week Physical Activity Intervention in Subjects With Increased Cardiometabolic Risk Shifts Innate Immune Function Towards a Less Proinflammatory State.

Noz MP, Hartman YAW, Hopman MTE, Willems PHGM, Tack CJ, Joosten LAB, Netea MG, Thijssen DHJ, Riksen NP.

J Am Heart Assoc. 2019 Nov 5;8(21):e013764. doi: 10.1161/JAHA.119.013764. Epub 2019 Oct 18.

16.

Gout.

Dalbeth N, Choi HK, Joosten LAB, Khanna PP, Matsuo H, Perez-Ruiz F, Stamp LK.

Nat Rev Dis Primers. 2019 Sep 26;5(1):69. doi: 10.1038/s41572-019-0115-y. Review.

PMID:
31558729
17.

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout.

Bursill D, Taylor WJ, Terkeltaub R, Abhishek A, So AK, Vargas-Santos AB, Gaffo AL, Rosenthal A, Tausche AK, Reginato A, Manger B, Sciré C, Pineda C, van Durme C, Lin CT, Yin C, Albert DA, Biernat-Kaluza E, Roddy E, Pascual E, Becce F, Perez-Ruiz F, Sivera F, Lioté F, Schett G, Nuki G, Filippou G, McCarthy G, da Rocha Castelar Pinheiro G, Ea HK, Tupinambá HA, Yamanaka H, Choi HK, Mackay J, ODell JR, Vázquez Mellado J, Singh JA, Fitzgerald JD, Jacobsson LTH, Joosten L, Harrold LR, Stamp L, Andrés M, Gutierrez M, Kuwabara M, Dehlin M, Janssen M, Doherty M, Hershfield MS, Pillinger M, Edwards NL, Schlesinger N, Kumar N, Slot O, Ottaviani S, Richette P, MacMullan PA, Chapman PT, Lipsky PE, Robinson P, Khanna PP, Gancheva RN, Grainger R, Johnson RJ, Te Kampe R, Keenan RT, Tedeschi SK, Kim S, Choi SJ, Fields TR, Bardin T, Uhlig T, Jansen T, Merriman T, Pascart T, Neogi T, Klück V, Louthrenoo W, Dalbeth N.

Ann Rheum Dis. 2019 Nov;78(11):1592-1600. doi: 10.1136/annrheumdis-2019-215933. Epub 2019 Sep 9.

PMID:
31501138
18.

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32.

Dos Santos JC, Barroso de Figueiredo AM, Teodoro Silva MV, Cirovic B, de Bree LCJ, Damen MSMA, Moorlag SJCFM, Gomes RS, Helsen MM, Oosting M, Keating ST, Schlitzer A, Netea MG, Ribeiro-Dias F, Joosten LAB.

Cell Rep. 2019 Sep 3;28(10):2659-2672.e6. doi: 10.1016/j.celrep.2019.08.004.

19.

Validation of cellular tests for Lyme borreliosis (VICTORY) study.

van de Schoor FR, Baarsma ME, Gauw SA, Joosten LAB, Kullberg BJ, van den Wijngaard CC, Hovius JW.

BMC Infect Dis. 2019 Aug 20;19(1):732. doi: 10.1186/s12879-019-4323-6.

20.

Transgenic mice expressing human IL-32 develop adipokine profiles resembling those of obesity-induced metabolic changes.

Damen MSMA, Ballak D, Sapinsley Z, Bai X, Chan ED, Seals DR, Popa CD, Joosten LAB.

Cytokine. 2020 Jan;125:154793. doi: 10.1016/j.cyto.2019.154793. Epub 2019 Aug 6.

PMID:
31398626
21.

IL-32 and its splice variants are associated with protection against Mycobacterium tuberculosis infection and skewing of Th1/Th17 cytokines.

Koeken VACM, Verrall AJ, Ardiansyah E, Apriani L, Dos Santos JC, Kumar V, Alisjahbana B, Hill PC, Joosten LAB, van Crevel R, van Laarhoven A.

J Leukoc Biol. 2020 Jan;107(1):113-118. doi: 10.1002/JLB.4AB0219-071R. Epub 2019 Aug 4.

22.

Long-Lasting Transcriptional Changes in Circulating Monocytes of Acute Q Fever Patients.

Raijmakers RP, Stenos J, Keijmel SP, Ter Horst R, Novakovic B, Nguyen C, Van Der Meer JW, Netea MG, Bleeker-Rovers CP, Joosten LA, Graves SR.

Open Forum Infect Dis. 2019 Jul 1;6(7). pii: ofz296. doi: 10.1093/ofid/ofz296.

23.

Measuring the Pancreatic β Cell Mass in Vivo with Exendin SPECT during Hyperglycemia and Severe Insulitis.

Joosten L, Brom M, Peeters H, Bos D, Himpe E, Bouwens L, Boerman O, Gotthardt M.

Mol Pharm. 2019 Sep 3;16(9):4024-4030. doi: 10.1021/acs.molpharmaceut.9b00728. Epub 2019 Aug 8.

PMID:
31345042
24.

Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells.

Bossel Ben-Moshe N, Hen-Avivi S, Levitin N, Yehezkel D, Oosting M, Joosten LAB, Netea MG, Avraham R.

Nat Commun. 2019 Jul 22;10(1):3266. doi: 10.1038/s41467-019-11257-y.

25.

A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans.

Jaeger M, Matzaraki V, Aguirre-Gamboa R, Gresnigt MS, Chu X, Johnson MD, Oosting M, Smeekens SP, Withoff S, Jonkers I, Perfect JR, van de Veerdonk FL, Kullberg BJ, Joosten LAB, Li Y, Wijmenga C, Netea MG, Kumar V.

J Infect Dis. 2019 Jul 31;220(5):862-872. doi: 10.1093/infdis/jiz206.

PMID:
31241743
26.

Non-specific effects of BCG in protozoal infections: tegumentary leishmaniasis and malaria.

Dos Santos JC, Vilela Teodoro Silva M, Ribeiro-Dias F, Joosten LAB.

Clin Microbiol Infect. 2019 Dec;25(12):1479-1483. doi: 10.1016/j.cmi.2019.06.002. Epub 2019 Jun 15. Review.

PMID:
31212075
27.

Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia.

Bekkering S, Stiekema LCA, Bernelot Moens S, Verweij SL, Novakovic B, Prange K, Versloot M, Roeters van Lennep JE, Stunnenberg H, de Winther M, Stroes ESG, Joosten LAB, Netea MG, Riksen NP.

Cell Metab. 2019 Jul 2;30(1):1-2. doi: 10.1016/j.cmet.2019.05.014. Epub 2019 Jun 13.

PMID:
31204280
28.

Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration.

Sloot YJE, Rabold K, Ulas T, De Graaf DM, Heinhuis B, Händler K, Schultze JL, Netea MG, Smit JWA, Joosten LAB, Netea-Maier RT.

Cell Oncol (Dordr). 2019 Oct;42(5):691-703. doi: 10.1007/s13402-019-00457-9. Epub 2019 Jun 14.

PMID:
31201646
29.

A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis.

Jaeger M, Pinelli M, Borghi M, Constantini C, Dindo M, van Emst L, Puccetti M, Pariano M, Ricaño-Ponce I, Büll C, Gresnigt MS, Wang X, Gutierrez Achury J, Jacobs CWM, Xu N, Oosting M, Arts P, Joosten LAB, van de Veerdonk FL, Veltman JA, Ten Oever J, Kullberg BJ, Feng M, Adema GJ, Wijmenga C, Kumar V, Sobel J, Gilissen C, Romani L, Netea MG.

Sci Transl Med. 2019 Jun 12;11(496). pii: eaar3558. doi: 10.1126/scitranslmed.aar3558.

PMID:
31189718
30.

Stroke Rate Variation and Anticoagulation Benefit in Atrial Fibrillation.

Joosten LPT, van Doorn S, Rutten FH, Geersing GJ.

Ann Intern Med. 2019 Jun 4;170(11):816-817. doi: 10.7326/L19-0129. No abstract available.

PMID:
31158860
31.

Aldosterone induces trained immunity: the role of fatty acid synthesis.

van der Heijden CDCC, Keating ST, Groh L, Joosten LAB, Netea MG, Riksen NP.

Cardiovasc Res. 2020 Feb 1;116(2):317-328. doi: 10.1093/cvr/cvz137.

PMID:
31119285
32.

Monitoring 111In-labelled polyisocyanopeptide (PIC) hydrogel wound dressings in full-thickness wounds.

Op 't Veld RC, Joosten L, van den Boomen OI, Boerman OC, Kouwer P, Middelkoop E, Rowan AE, Jansen JA, Walboomers XF, Wagener FADTG.

Biomater Sci. 2019 Jul 1;7(7):3041-3050. doi: 10.1039/c9bm00661c. Epub 2019 May 22.

PMID:
31115398
33.

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP, Ter Horst R, Roerink ME, Novakovic B, Joosten LAB, van der Meer JWM, Netea MG, Bleeker-Rovers CP.

J Transl Med. 2019 May 14;17(1):157. doi: 10.1186/s12967-019-1906-3.

34.

High LDL-C levels attenuate onset of inflammation and cartilage destruction in antigen-induced arthritis.

Ascone G, Di Ceglie I, van den Bosch MHJ, Kruisbergen NNL, Walgreen B, Sloetjes AW, Lindhout E, Joosten LAB, van de Loo FAJ, Koenders MI, van der Kraan PM, Blom AB, van Lent PLEM.

Clin Exp Rheumatol. 2019 Nov-Dec;37(6):983-993. Epub 2019 May 7.

PMID:
31074720
35.

Exendin-4 analogs in insulinoma theranostics.

Jansen TJP, van Lith SAM, Boss M, Brom M, Joosten L, Béhé M, Buitinga M, Gotthardt M.

J Labelled Comp Radiopharm. 2019 Aug;62(10):656-672. doi: 10.1002/jlcr.3750.

36.

Immunometabolism orchestrates training of innate immunity in atherosclerosis.

van Tuijl J, Joosten LAB, Netea MG, Bekkering S, Riksen NP.

Cardiovasc Res. 2019 Jul 1;115(9):1416-1424. doi: 10.1093/cvr/cvz107.

37.

Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes.

Mirea AM, Toonen EJM, van den Munckhof I, Munsterman ID, Tjwa ETTL, Jaeger M, Oosting M, Schraa K, Rutten JHW, van der Graaf M, Riksen NP, de Graaf J, Netea MG, Tack CJ, Chavakis T, Joosten LAB.

Mol Med. 2019 May 2;25(1):16. doi: 10.1186/s10020-019-0084-3.

38.

Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides.

Neidhart M, Pajak A, Laskari K, Riksen NP, Joosten LAB, Netea MG, Lutgens E, Stroes ESG, Ciurea A, Distler O, Grigorian M, Karouzakis E.

Front Immunol. 2019 Apr 15;10:791. doi: 10.3389/fimmu.2019.00791. eCollection 2019.

39.

A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP, van der Meer JWM, Joosten LAB, Netea MG, Bleeker-Rovers CP.

Eur J Immunol. 2019 Jul;49(7):1015-1022. doi: 10.1002/eji.201848012. Epub 2019 May 9.

PMID:
31001808
40.

Prevalence and determinants of persistent symptoms after treatment for Lyme borreliosis: study protocol for an observational, prospective cohort study (LymeProspect).

Vrijmoeth HD, Ursinus J, Harms MG, Zomer TP, Gauw SA, Tulen AD, Kremer K, Sprong H, Knoop H, Vermeeren YM, van Kooten B, Joosten LAB, Kullberg BJ, Hovius JWR, van den Wijngaard CC.

BMC Infect Dis. 2019 Apr 15;19(1):324. doi: 10.1186/s12879-019-3949-8.

41.

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk.

Kurilshikov A, van den Munckhof ICL, Chen L, Bonder MJ, Schraa K, Rutten JHW, Riksen NP, de Graaf J, Oosting M, Sanna S, Joosten LAB, van der Graaf M, Brand T, Koonen DPY, van Faassen M; LifeLines DEEP Cohort Study, BBMRI Metabolomics Consortium, Slagboom PE, Xavier RJ, Kuipers F, Hofker MH, Wijmenga C, Netea MG, Zhernakova A, Fu J.

Circ Res. 2019 Jun 7;124(12):1808-1820. doi: 10.1161/CIRCRESAHA.118.314642. Epub 2019 Apr 11.

PMID:
30971183
42.

Therapeutic targeting of trained immunity.

Mulder WJM, Ochando J, Joosten LAB, Fayad ZA, Netea MG.

Nat Rev Drug Discov. 2019 Jul;18(7):553-566. doi: 10.1038/s41573-019-0025-4. Review.

PMID:
30967658
43.

Interacting, Nonspecific, Immunological Effects of Bacille Calmette-Guérin and Tetanus-diphtheria-pertussis Inactivated Polio Vaccinations: An Explorative, Randomized Trial.

Blok BA, de Bree LCJ, Diavatopoulos DA, Langereis JD, Joosten LAB, Aaby P, van Crevel R, Benn CS, Netea MG.

Clin Infect Dis. 2020 Jan 16;70(3):455-463. doi: 10.1093/cid/ciz246.

PMID:
30919883
44.

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity.

Huang Z, Wang J, Xu X, Wang H, Qiao Y, Chu WC, Xu S, Chai L, Cottier F, Pavelka N, Oosting M, Joosten LAB, Netea M, Ng CYL, Leong KP, Kundu P, Lam KP, Pettersson S, Wang Y.

Nat Microbiol. 2019 May;4(5):766-773. doi: 10.1038/s41564-019-0381-1. Epub 2019 Mar 4.

PMID:
30833732
45.

Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases.

Sanna S, van Zuydam NR, Mahajan A, Kurilshikov A, Vich Vila A, Võsa U, Mujagic Z, Masclee AAM, Jonkers DMAE, Oosting M, Joosten LAB, Netea MG, Franke L, Zhernakova A, Fu J, Wijmenga C, McCarthy MI.

Nat Genet. 2019 Apr;51(4):600-605. doi: 10.1038/s41588-019-0350-x. Epub 2019 Feb 18.

46.

Predictive value of ex-vivo drug-inhibited cytokine production for clinical response to biologic DMARD therapy in rheumatoid arthritis.

Tweehuysen L, den Broeder AA, Schraa K, Netea MG, van den Hoogen FHJ, Joosten LAB.

Clin Exp Rheumatol. 2019 May-Jun;37(3):367-372. Epub 2019 Feb 7.

PMID:
30767874
47.

Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression.

Cleophas MCP, Crişan TO, Klück V, Hoogerbrugge N, Netea-Maier RT, Dinarello CA, Netea MG, Joosten LAB.

Arthritis Res Ther. 2019 Feb 6;21(1):50. doi: 10.1186/s13075-019-1834-x.

48.

Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males.

Cleophas MCP, Ratter JM, Bekkering S, Quintin J, Schraa K, Stroes ES, Netea MG, Joosten LAB.

Sci Rep. 2019 Jan 28;9(1):775. doi: 10.1038/s41598-018-37246-7.

49.

Cytokine profiles in patients with Q fever fatigue syndrome.

Raijmakers RPH, Koeken VACM, Jansen AFM, Keijmel SP, Roerink ME, Joosten LAB, Netea MG, van der Meer JWM, Bleeker-Rovers CP.

J Infect. 2019 May;78(5):349-357. doi: 10.1016/j.jinf.2019.01.006. Epub 2019 Jan 23.

PMID:
30684502
50.

Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens.

Netea MG, Schlitzer A, Placek K, Joosten LAB, Schultze JL.

Cell Host Microbe. 2019 Jan 9;25(1):13-26. doi: 10.1016/j.chom.2018.12.006. Review.

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