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Items: 1 to 50 of 94

1.

Development and evaluation of an ultrasensitive free VEGF-A immunoassay for analysis of human aqueous humor.

Göpfert JC, Reiser A, Carcamo Yañez VA, Pohle A, Wessels U, Heine A, Joos TO, Petit-Frère C, Nogoceke E, Stubenrauch KG.

Bioanalysis. 2019 May;11(9):875-886. doi: 10.4155/bio-2019-0044. Epub 2019 May 9.

PMID:
31070047
2.

Application of Mass Spectrometry-Based Immunoassays for the Species- and Tissue-Specific Quantification of Banned Processed Animal Proteins in Feeds.

Steinhilber AE, Schmidt FF, Naboulsi W, Planatscher H, Niedzwiecka A, Zagon J, Braeuning A, Lampen A, Joos TO, Poetz O.

Anal Chem. 2019 Mar 19;91(6):3902-3911. doi: 10.1021/acs.analchem.8b04652. Epub 2019 Feb 27.

PMID:
30768891
3.

Serum Inflammatory Profile for the Discrimination of Clinical Subtypes in Parkinson's Disease.

Yilmaz R, Strafella AP, Bernard A, Schulte C, van den Heuvel L, Schneiderhan-Marra N, Knorpp T, Joos TO, Leypoldt F, Geritz J, Hansen C, Heinzel S, Apel A, Gasser T, Lang AE, Berg D, Maetzler W, Marras C.

Front Neurol. 2018 Dec 21;9:1123. doi: 10.3389/fneur.2018.01123. eCollection 2018.

4.

Species Differentiation and Quantification of Processed Animal Proteins and Blood Products in Fish Feed Using an 8-Plex Mass Spectrometry-Based Immunoassay.

Steinhilber AE, Schmidt FF, Naboulsi W, Planatscher H, Niedzwiecka A, Zagon J, Braeuning A, Lampen A, Joos TO, Poetz O.

J Agric Food Chem. 2018 Oct 3;66(39):10327-10335. doi: 10.1021/acs.jafc.8b03934. Epub 2018 Sep 24.

PMID:
30222351
5.

Increased Energy Expenditure, Lipolysis and Hyperinsulinemia Confer Resistance to Central Obesity and Type 2 Diabetes in Mice Lacking Alpha2α-Adrenoceptors.

Ruohonen ST, Valve L, Tuomainen K, Ailanen L, Röyttä M, Manz G, Baur N, Joos TO, Savontaus E, Scheinin M.

Neuroendocrinology. 2018;107(4):324-339. doi: 10.1159/000492387. Epub 2018 Jul 24.

PMID:
30041171
6.

Study of the Humoral Immune Response towards HCV Genotype 4 Using a Bead-Based Multiplex Serological Assay.

Filomena A, Göpfert JC, Duffy D, Pol S, Abdel-Hamid M, Esmat G, Fontanet A, Albert ML, Joos TO, Schneiderhan-Marra N.

High Throughput. 2017 Oct 30;6(4). pii: E15. doi: 10.3390/ht6040015.

7.

Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response against the Six Pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori.

Filomena A, Pessler F, Akmatov MK, Krause G, Duffy D, Gärtner B, Gerhard M, Albert ML, Joos TO, Schneiderhan-Marra N.

High Throughput. 2017 Oct 30;6(4). pii: E14. doi: 10.3390/ht6040014.

8.

Peptide-Based Sandwich Immunoassay for the Quantification of the Membrane Transporter Multidrug Resistance Protein 1.

Poetz O, Dieze T, Hammer H, Weiß F, Sommersdorf C, Templin MF, Esdar C, Zimmermann A, Stevanovic S, Bedke J, Stenzl A, Joos TO.

Anal Chem. 2018 May 1;90(9):5788-5794. doi: 10.1021/acs.analchem.8b00152. Epub 2018 Apr 12.

PMID:
29570278
9.

Development and Validation of an Ultrasensitive Procalcitonin Sandwich Immunoassay.

Carcamo Yañez VA, Göpfert JC, Otto M, Tumani H, Peter A, Joos TO.

High Throughput. 2017 Nov 16;6(4). pii: E18. doi: 10.3390/ht6040018.

10.

Mass Spectrometry-Based Immunoassay for the Quantification of Banned Ruminant Processed Animal Proteins in Vegetal Feeds.

Steinhilber AE, Schmidt FF, Naboulsi W, Planatscher H, Niedzwiecka A, Zagon J, Braeuning A, Lampen A, Joos TO, Poetz O.

Anal Chem. 2018 Mar 20;90(6):4135-4143. doi: 10.1021/acs.analchem.8b00120. Epub 2018 Mar 7.

PMID:
29470057
11.

Direct Quantification of Cytochromes P450 and Drug Transporters-A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates.

Weiß F, Hammer HS, Klein K, Planatscher H, Zanger UM, Norén A, Wegler C, Artursson P, Joos TO, Poetz O.

Drug Metab Dispos. 2018 Apr;46(4):387-396. doi: 10.1124/dmd.117.078626. Epub 2018 Jan 17.

PMID:
29343608
12.

Performance of a Multiplex Serological Helicobacter pylori Assay on a Novel Microfluidic Assay Platform.

Filomena A, Guenther A, Planatscher H, Topin F, She J, Formichella L, Terradot L, Gerhard M, Joos TO, Meyer H, Schneiderhan-Marra N.

Proteomes. 2017 Oct 3;5(4). pii: E24. doi: 10.3390/proteomes5040024.

13.

Tau plasma levels in subjective cognitive decline: Results from the DELCODE study.

Müller S, Preische O, Göpfert JC, Yañez VAC, Joos TO, Boecker H, Düzel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, Peters O, Menne F, Schipke CG, Schneider A, Spottke A, Fließbach K, Kilimann I, Teipel S, Wagner M, Wiltfang J, Jessen F, Laske C.

Sci Rep. 2017 Aug 25;7(1):9529. doi: 10.1038/s41598-017-08779-0.

14.

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes.

Wegler C, Gaugaz FZ, Andersson TB, Wiśniewski JR, Busch D, Gröer C, Oswald S, Norén A, Weiss F, Hammer HS, Joos TO, Poetz O, Achour B, Rostami-Hodjegan A, van de Steeg E, Wortelboer HM, Artursson P.

Mol Pharm. 2017 Sep 5;14(9):3142-3151. doi: 10.1021/acs.molpharmaceut.7b00364. Epub 2017 Aug 16.

15.

Diagnostic Performance of Tuberculosis-Specific IgG Antibody Profiles in Patients with Presumptive Tuberculosis from Two Continents.

Broger T, Basu Roy R, Filomena A, Greef CH, Rimmele S, Havumaki J, Danks D, Schneiderhan-Marra N, Gray CM, Singh M, Rosenkrands I, Andersen P, Husar GM, Joos TO, Gennaro ML, Lochhead MJ, Denkinger CM, Perkins MD.

Clin Infect Dis. 2017 Apr 1;64(7):947-955. doi: 10.1093/cid/cix023.

16.

Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease.

Brockmann K, Schulte C, Schneiderhan-Marra N, Apel A, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol JC, Cormier F, Knorpp T, Joos TO, Bernard A, Gasser T, Marras C, Schüle B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Berg D, Maetzler W.

Eur J Neurol. 2017 Feb;24(2):427-e6. doi: 10.1111/ene.13223.

PMID:
28102045
17.

Prevention of tau increase in cerebrospinal fluid of APP transgenic mice suggests downstream effect of BACE1 inhibition.

Schelle J, Häsler LM, Göpfert JC, Joos TO, Vanderstichele H, Stoops E, Mandelkow EM, Neumann U, Shimshek DR, Staufenbiel M, Jucker M, Kaeser SA.

Alzheimers Dement. 2017 Jun;13(6):701-709. doi: 10.1016/j.jalz.2016.09.005. Epub 2016 Oct 14.

PMID:
27750032
18.

Inhibition of β-catenin signaling by phenobarbital in hepatoma cells in vitro.

Groll N, Petrikat T, Vetter S, Wenz C, Dengjel J, Gretzmeier C, Weiss F, Poetz O, Joos TO, Schwarz M, Braeuning A.

Toxicology. 2016 Aug 31;370:94-105. doi: 10.1016/j.tox.2016.09.018. Epub 2016 Sep 30.

PMID:
27693619
19.

A bead-based western for high-throughput cellular signal transduction analyses.

Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, Joos TO, Kling S, Poetz O, Fehm T, Neubauer H, Kuster B, Templin MF.

Nat Commun. 2016 Sep 23;7:12852. doi: 10.1038/ncomms12852.

20.

Impact of Feeding Strategies on the Scalable Expansion of Human Pluripotent Stem Cells in Single-Use Stirred Tank Bioreactors.

Kropp C, Kempf H, Halloin C, Robles-Diaz D, Franke A, Scheper T, Kinast K, Knorpp T, Joos TO, Haverich A, Martin U, Zweigerdt R, Olmer R.

Stem Cells Transl Med. 2016 Oct;5(10):1289-1301. Epub 2016 Jul 1.

21.

Inflammatory profile in LRRK2-associated prodromal and clinical PD.

Brockmann K, Apel A, Schulte C, Schneiderhan-Marra N, Pont-Sunyer C, Vilas D, Ruiz-Martinez J, Langkamp M, Corvol JC, Cormier F, Knorpp T, Joos TO, Gasser T, Schüle B, Aasly JO, Foroud T, Marti-Masso JF, Brice A, Tolosa E, Marras C, Berg D, Maetzler W.

J Neuroinflammation. 2016 May 24;13(1):122. doi: 10.1186/s12974-016-0588-5.

22.

Coordinate regulation of Cyp2e1 by β-catenin- and hepatocyte nuclear factor 1α-dependent signaling.

Groll N, Petrikat T, Vetter S, Colnot S, Weiss F, Poetz O, Joos TO, Rothbauer U, Schwarz M, Braeuning A.

Toxicology. 2016 Mar 28;350-352:40-8. doi: 10.1016/j.tox.2016.05.004. Epub 2016 May 3.

PMID:
27153753
23.

Coordinating Role of RXRα in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling.

Keller R, Klein M, Thomas M, Dräger A, Metzger U, Templin MF, Joos TO, Thasler WE, Zell A, Zanger UM.

PLoS Comput Biol. 2016 Jan 4;12(1):e1004431. doi: 10.1371/journal.pcbi.1004431. eCollection 2016 Jan.

24.

Bead-Based Peptide Arrays for Profiling the Specificity of Modification State-Specific Antibodies.

Filomena A, Beiter Y, Templin MF, Joos TO, Schneiderhan-Marra N, Poetz O.

Methods Mol Biol. 2015;1348:251-65. doi: 10.1007/978-1-4939-2999-3_22.

PMID:
26424278
25.

Phenobarbital inhibits calpain activity and expression in mouse hepatoma cells.

Groll N, Kollotzek F, Goepfert J, Joos TO, Schwarz M, Braeuning A.

Biol Chem. 2016 Jan;397(1):91-6. doi: 10.1515/hsz-2015-0223.

PMID:
26351921
26.

A bead-based multiplex sandwich immunoassay to assess the abundance and posttranslational modification state of β-catenin.

Groll N, Sommersdorf C, Joos TO, Poetz O.

Methods Mol Biol. 2015;1295:441-53. doi: 10.1007/978-1-4939-2550-6_31.

PMID:
25820739
27.

Plasma matrix metalloproteinase 2 levels and breast cancer risk.

Aroner SA, Rosner BA, Tamimi RM, Tworoger SS, Baur N, Joos TO, Hankinson SE.

Cancer Epidemiol. 2015 Jun;39(3):321-7. doi: 10.1016/j.canep.2015.02.010. Epub 2015 Mar 19.

28.

Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry.

Weiß F, Schnabel A, Planatscher H, van den Berg BH, Serschnitzki B, Nuessler AK, Thasler WE, Weiss TS, Reuss M, Stoll D, Templin MF, Joos TO, Marcus K, Poetz O.

Sci Rep. 2015 Mar 4;5:8759. doi: 10.1038/srep08759.

29.

Selective, efficient modulation of activated CD4+ αβT cells by the novel humanized antibody GZ-αβTCR targeting human αβTCR.

Blank G, Welker C, Haarer J, Sterk M, Nadalin S, Yañez VA, Joos TO, Menrad A, Snell D, LaCorcia G, Königsrainer A, Handgretinger R, Schilbach K.

Bone Marrow Transplant. 2015 Mar;50(3):390-401. doi: 10.1038/bmt.2014.263. Epub 2014 Nov 17.

PMID:
25402416
30.

Plasma matrix metalloproteinase 1, 3, and 7 levels and breast cancer risk in the Nurses' Health study.

Aroner SA, Rosner BA, Tamimi RM, Tworoger SS, Baur N, Joos TO, Hankinson SE.

Cancer Causes Control. 2014 Dec;25(12):1717-23. doi: 10.1007/s10552-014-0462-7. Epub 2014 Sep 16.

31.

Catch and measure-mass spectrometry-based immunoassays in biomarker research.

Weiß F, van den Berg BH, Planatscher H, Pynn CJ, Joos TO, Poetz O.

Biochim Biophys Acta. 2014 May;1844(5):927-32. doi: 10.1016/j.bbapap.2013.09.010. Epub 2013 Sep 21. Review.

PMID:
24060810
32.

G protein-coupled receptor quantification using peptide group-specific enrichment combined with internal peptide standard reporter calibration.

Eisen D, Planatscher H, Hardie DB, Kraushaar U, Pynn CJ, Stoll D, Borchers C, Joos TO, Poetz O.

J Proteomics. 2013 Sep 2;90:85-95. doi: 10.1016/j.jprot.2013.02.017. Epub 2013 Mar 14.

PMID:
23500134
33.

From spots to beads-PTM-peptide bead arrays for the characterization of anti-histone antibodies.

Heubach Y, Planatscher H, Sommersdorf C, Maisch D, Maier J, Joos TO, Templin MF, Poetz O.

Proteomics. 2013 Mar;13(6):1010-5. doi: 10.1002/pmic.201200383.

PMID:
23401470
34.

Characterization of immunologically active drugs in a novel organotypic co-culture model of the human gut and whole blood.

Schmohl M, Schneiderhan-Marra N, Baur N, Hefner K, Blum M, Stein GM, Joos TO, Schmolz M.

Int Immunopharmacol. 2012 Dec;14(4):722-8. doi: 10.1016/j.intimp.2012.10.010. Epub 2012 Oct 24.

PMID:
23102666
35.

Superficial wound swabbing: a novel method of sampling and processing wound fluid for subsequent immunoassay analysis in diabetic foot ulcerations.

Schmohl M, Beckert S, Joos TO, Königsrainer A, Schneiderhan-Marra N, Löffler MW.

Diabetes Care. 2012 Nov;35(11):2113-20. doi: 10.2337/dc11-2547. Epub 2012 Jul 26.

36.

Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia.

Moskalev EA, Luckert K, Vorobjev IA, Mastitsky SE, Gladkikh AA, Stephan A, Schrenk M, Kaplanov KD, Kalashnikova OB, Pötz O, Joos TO, Hoheisel JD.

BMC Cancer. 2012 Jun 6;12:213. doi: 10.1186/1471-2407-12-213.

37.

A Miniaturized Ligand Binding Assay for EGFR.

Schwenk JM, Poetz O, Zeillinger R, Joos TO.

Int J Proteomics. 2012;2012:247059. doi: 10.1155/2012/247059. Epub 2012 Apr 8.

38.

Combining ultracentrifugation and peptide termini group-specific immunoprecipitation for multiplex plasma protein analysis.

Volk S, Schreiber TD, Eisen D, Wiese C, Planatscher H, Pynn CJ, Stoll D, Templin MF, Joos TO, Pötz O.

Mol Cell Proteomics. 2012 Jul;11(7):O111.015438. doi: 10.1074/mcp.O111.015438. Epub 2012 Apr 23.

39.

A dual array-based approach to assess the abundance and posttranslational modification state of signaling proteins.

Luckert K, Gujral TS, Chan M, Sevecka M, Joos TO, Sorger PK, Macbeath G, Pötz O.

Sci Signal. 2012 Jan 10;5(206):pl1. doi: 10.1126/scisignal.2002372. Erratum in: Sci Signal. 2012 Aug 21;5(238):er5. Sevecka, Mark [added].

40.

Functional analysis of Rho GTPase activation and inhibition in a bead-based miniaturized format.

Schmohl M, Rimmele S, Gierschik P, Joos TO, Schneiderhan-Marra N.

Methods Mol Biol. 2012;827:271-82. doi: 10.1007/978-1-61779-442-1_18.

PMID:
22144281
41.

Receptor tyrosine kinase inhibitor profiling using bead-based multiplex sandwich immunoassays.

Pötz O, Schneiderhan-Marra N, Henzler T, Herget T, Joos TO.

Methods Mol Biol. 2012;795:191-202. doi: 10.1007/978-1-61779-337-0_13.

PMID:
21960224
42.

[Protein microarrays and personalized medicine].

Yu X, Schneiderhan-Marra N, Joos TO.

Ann Biol Clin (Paris). 2011 Jan-Feb;69(1):17-29. doi: 10.1684/abc.2010.0512. Review. French.

43.

Snapshots of protein dynamics and post-translational modifications in one experiment--beta-catenin and its functions.

Luckert K, Götschel F, Sorger PK, Hecht A, Joos TO, Pötz O.

Mol Cell Proteomics. 2011 May;10(5):M110.007377. doi: 10.1074/mcp.M110.007377. Epub 2011 Mar 4.

44.

Bead-based protein-protein interaction assays for the analysis of Rho GTPase signaling.

Rimmele S, Gierschik P, Joos TO, Schneiderhan-Marra N.

J Mol Recognit. 2010 Nov-Dec;23(6):543-50. doi: 10.1002/jmr.1051.

PMID:
21031432
45.

Targeting peptide termini, a novel immunoaffinity approach to reduce complexity in mass spectrometric protein identification.

Hoeppe S, Schreiber TD, Planatscher H, Zell A, Templin MF, Stoll D, Joos TO, Poetz O.

Mol Cell Proteomics. 2011 Feb;10(2):M110.002857. doi: 10.1074/mcp.M110.002857. Epub 2010 Oct 20.

46.

µFBI: a microfluidic bead-based immunoassay for multiplexed detection of proteins from a µL sample volume.

Yu X, Hartmann M, Wang Q, Poetz O, Schneiderhan-Marra N, Stoll D, Kazmaier C, Joos TO.

PLoS One. 2010 Oct 1;5(10). pii: e13125. doi: 10.1371/journal.pone.0013125.

47.

Authors's reply.

Punyadeera C, Schneider EM, Schaffer D, Hsu HY, Joos TO, Kriebel F, Weiss M, Verhaegh WF.

J Emerg Trauma Shock. 2010 Jul;3(3):308. No abstract available.

48.

Sequential multiplex analyte capturing for phosphoprotein profiling.

Poetz O, Henzler T, Hartmann M, Kazmaier C, Templin MF, Herget T, Joos TO.

Mol Cell Proteomics. 2010 Nov;9(11):2474-81. doi: 10.1074/mcp.M110.002709. Epub 2010 Aug 3.

49.

Multiplexed immunoassays for the analysis of breast cancer biopsies.

Schneiderhan-Marra N, Sauer G, Kazmaier C, Hsu HY, Koretz K, Deissler H, Joos TO.

Anal Bioanal Chem. 2010 Aug;397(8):3329-38. doi: 10.1007/s00216-010-3873-7. Epub 2010 Jul 18.

PMID:
20640897
50.

A biomarker panel to discriminate between systemic inflammatory response syndrome and sepsis and sepsis severity.

Punyadeera C, Schneider EM, Schaffer D, Hsu HY, Joos TO, Kriebel F, Weiss M, Verhaegh WF.

J Emerg Trauma Shock. 2010 Jan;3(1):26-35. doi: 10.4103/0974-2700.58666.

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