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Acute blood pressure change with methylphenidate is associated with improvement in attention performance in children with ADHD.

Traicu A, Grizenko N, Fortier MÈ, Fageera W, Sengupta SM, Joober R.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Aug 12:109732. doi: 10.1016/j.pnpbp.2019.109732. [Epub ahead of print]


Editorial: How youth mental healthcare is being transformed in diverse settings across Canada: Reflections on the experience of the ACCESS Open Minds network.

Iyer SN, Boksa P, Joober R.

Early Interv Psychiatry. 2019 Jun;13 Suppl 1:8-11. doi: 10.1111/eip.12811. No abstract available.


Improving youth mental wellness services in an Indigenous context in Ulukhaktok, Northwest Territories: ACCESS Open Minds Project.

Etter M, Goose A, Nossal M, Chishom-Nelson J, Heck C, Joober R, Boksa P, Lal S, Shah JL, Andersson N, Iyer SN, Malla A.

Early Interv Psychiatry. 2019 Jun;13 Suppl 1:35-41. doi: 10.1111/eip.12816.


Transforming youth mental health services in a large urban centre: ACCESS Open Minds Edmonton.

Abba-Aji A, Hay K, Kelland J, Mummery C, Urichuk L, Gerdes C, Snaterse M, Chue P, Lal S, Joober R, Boksa P, Malla A, N Iyer S, Shah JL.

Early Interv Psychiatry. 2019 Jun;13 Suppl 1:14-19. doi: 10.1111/eip.12813.


Transforming youth mental health care in a semi-urban and rural region of Canada: A service description of ACCESS Open Minds Chatham-Kent.

Reaume-Zimmer P, Chandrasena R, Malla A, Joober R, Boksa P, Shah JL, Iyer SN, Lal S.

Early Interv Psychiatry. 2019 Jun;13 Suppl 1:48-55. doi: 10.1111/eip.12818.


Improving mental health services for homeless youth in downtown Montreal, Canada: Partnership between a local network and ACCESS Esprits ouverts (Open Minds), a National Services Transformation Research Initiative.

Abdel-Baki A, Aubin D, Morisseau-Guillot R, Lal S, Dupont MÈ, Bauco P, Shah JL, Joober R, Boksa P, Malla A, Iyer SN.

Early Interv Psychiatry. 2019 Jun;13 Suppl 1:20-28. doi: 10.1111/eip.12814.


ACCESS Open Minds at the University of Alberta: Transforming student mental health services in a large Canadian post-secondary educational institution.

Vallianatos H, Friese K, Perez JM, Slessor J, Thind R, Dunn J, Chisholm-Nelson J, Joober R, Boksa P, Lal S, Malla A, Iyer SN, Shah JL.

Early Interv Psychiatry. 2019 Jun;13 Suppl 1:56-64. doi: 10.1111/eip.12819.


Sex Differences in Clinical and Functional Outcomes among Patients Treated in an Early Intervention Service for Psychotic Disorders: An Observational Study.

Dama M, Veru F, Schmitz N, Shah J, Iyer S, Joober R, Malla A.

Can J Psychiatry. 2019 Jun 12:706743719854069. doi: 10.1177/0706743719854069. [Epub ahead of print]


Short duration of untreated psychosis enhances negative symptom remission in extended early intervention service for psychosis.

Dama M, Shah J, Norman R, Iyer S, Joober R, Schmitz N, Abdel-Baki A, Malla A.

Acta Psychiatr Scand. 2019 Jul;140(1):65-76. doi: 10.1111/acps.13033. Epub 2019 Apr 23.


Testing the Effectiveness of Implementing a Model of Mental Healthcare Involving Trained Lay Health Workers in Treating Major Mental Disorders Among Youth in a Conflict-Ridden, Low-Middle Income Environment: Part II Results.

Malla A, Margoob M, Iyer S, Majid A, Lal S, Joober R, Issaoui Mansouri B.

Can J Psychiatry. 2019 Sep;64(9):630-637. doi: 10.1177/0706743719839314. Epub 2019 Apr 1.


A Model of Mental Health Care Involving Trained Lay Health Workers for Treatment of Major Mental Disorders Among Youth in a Conflict-Ridden, Low-Middle Income Environment: Part I Adaptation and Implementation.

Malla A, Margoob M, Iyer S, Joober R, Lal S, Thara R, Mushtaq H, Mansouri BI.

Can J Psychiatry. 2019 Sep;64(9):621-629. doi: 10.1177/0706743719839318. Epub 2019 Mar 27.


The Effects of Methylphenidate (Ritalin) on the Neurophysiology of the Monkey Caudal Prefrontal Cortex.

Tremblay S, Pieper F, Sachs A, Joober R, Martinez-Trujillo J.

eNeuro. 2019 Mar 4;6(1). pii: ENEURO.0371-18.2018. doi: 10.1523/ENEURO.0371-18.2018. eCollection 2019 Jan-Feb.


Structural Associations of Cortical Contrast and Thickness in First Episode Psychosis.

Makowski C, Lewis JD, Lepage C, Malla AK, Joober R, Lepage M, Evans AC.

Cereb Cortex. 2019 Mar 7. pii: bhz040. doi: 10.1093/cercor/bhz040. [Epub ahead of print]


What do DNA methylation studies tell us about depression? A systematic review.

Li M, D'Arcy C, Li X, Zhang T, Joober R, Meng X.

Transl Psychiatry. 2019 Feb 4;9(1):68. doi: 10.1038/s41398-019-0412-y.


Caught in the "NEET Trap": The Intersection Between Vocational Inactivity and Disengagement From an Early Intervention Service for Psychosis.

Maraj A, Mustafa S, Joober R, Malla A, Shah JL, Iyer SN.

Psychiatr Serv. 2019 Apr 1;70(4):302-308. doi: 10.1176/ Epub 2019 Feb 5.


Medication adherence in first episode psychosis: the role of pre-onset subthreshold symptoms.

Daneault JG, Maraj A, Lepage M, Malla A, Schmitz N, Iyer SN, Joober R, Shah JL.

Acta Psychiatr Scand. 2019 Apr;139(4):336-347. doi: 10.1111/acps.13011.


A longitudinal, epigenome-wide study of DNA methylation in anorexia nervosa: results in actively ill, partially weight-restored, long-term remitted and non-eating-disordered women

Steiger H, Booij L, Kahan `, McGregor K, Thaler L, Fletcher E, Labbe A, Joober R, Israël M, Szyf M, Agellon LB, Gauvin L, St-Hilaire A, Rossi E.

J Psychiatry Neurosci. 2019 May 1;44(3):205-213.


Neural function in DCC mutation carriers with and without mirror movements.

Vosberg DE, Beaulé V, Torres-Berrío A, Cooke D, Chalupa A, Jaworska N, Cox SML, Larcher K, Zhang Y, Allard D, Durand F, Dagher A, Benkelfat C, Srour M, Tampieri D, La Piana R, Joober R, Lepore F, Rouleau G, Pascual-Leone A, Fox MD, Flores C, Leyton M, Théoret H.

Ann Neurol. 2019 Mar;85(3):433-442. doi: 10.1002/ana.25418. Epub 2019 Feb 4.


The Trier Social Stress Test in first episode psychosis patients: Impact of perceived stress, protective factors and childhood trauma.

Seitz R, Vracotas N, Bechard-Evans L, King S, Abadi S, Joober R, Shah JL, Malla AK, Pruessner M.

Psychoneuroendocrinology. 2019 Jul;105:155-163. doi: 10.1016/j.psyneuen.2019.01.010. Epub 2019 Jan 11. Review.


From the neo-Kraepelinian framework to the new mechanical philosophy of psychiatry: regaining common sense

Joober R, Tabbane K.

J Psychiatry Neurosci. 2019 Jan 1;44(1):3-7. No abstract available.


Canadian response to need for transformation of youth mental health services: ACCESS Open Minds (Esprits ouverts).

Malla A, Iyer S, Shah J, Joober R, Boksa P, Lal S, Fuhrer R, Andersson N, Abdel-Baki A, Hutt-MacLeod D, Beaton A, Reaume-Zimmer P, Chisholm-Nelson J, Rousseau C, Chandrasena R, Bourque J, Aubin D, Levasseur MA, Winkelmann I, Etter M, Kelland J, Tait C, Torrie J, Vallianatos H; ACCESS Open Minds Youth Mental Health Network.

Early Interv Psychiatry. 2019 Jun;13(3):697-706. doi: 10.1111/eip.12772. Epub 2018 Dec 16.


Cognitive capacity similarly predicts insight into symptoms in first- and multiple-episode psychosis.

Sauvé G, Kline RB, Shah JL, Joober R, Malla A, Brodeur MB, Lepage M.

Schizophr Res. 2019 Apr;206:236-243. doi: 10.1016/j.schres.2018.11.013. Epub 2018 Dec 1.


Exome sequencing of sporadic childhood-onset schizophrenia suggests the contribution of X-linked genes in males.

Ambalavanan A, Chaumette B, Zhou S, Xie P, He Q, Spiegelman D, Dionne-Laporte A, Bourassa CV, Therrien M, Rochefort D, Xiong L, Dion PA, Joober R, Rapoport JL, Girard SL, Rouleau GA.

Am J Med Genet B Neuropsychiatr Genet. 2019 Sep;180(6):335-340. doi: 10.1002/ajmg.b.32683. Epub 2018 Oct 30.


Association of Pre-onset Subthreshold Psychotic Symptoms With Longitudinal Outcomes During Treatment of a First Episode of Psychosis.

Rosengard RJ, Malla A, Mustafa S, Iyer SN, Joober R, Bodnar M, Lepage M, Shah JL.

JAMA Psychiatry. 2019 Jan 1;76(1):61-70. doi: 10.1001/jamapsychiatry.2018.2552.


Does an integrated outreach intervention targeting multiple stages of early psychosis improve the identification of individuals at clinical high risk?

McIlwaine SV, Jordan G, Pruessner M, Malla A, Faridi K, Iyer SN, Joober R, Shah JL.

Early Interv Psychiatry. 2019 Aug;13(4):989-992. doi: 10.1111/eip.12750. Epub 2018 Oct 10.


Comparing cognitive clusters across first- and multiple-episode of psychosis.

Sauvé G, Malla A, Joober R, Brodeur MB, Lepage M.

Psychiatry Res. 2018 Nov;269:707-718. doi: 10.1016/j.psychres.2018.08.119. Epub 2018 Aug 30.


Dissecting genetic cross-talk between ADHD and other neurodevelopmental disorders: Evidence from behavioural, pharmacological and brain imaging investigations.

Sengupta SM, Fotopoulos N, Devenyi GA, Fortier MÈ, Ter-Stepanian M, Sagliker S, Karama S, Mallar Chakravarty M, Labbe A, Grizenko N, Joober R.

Psychiatry Res. 2018 Nov;269:652-657. doi: 10.1016/j.psychres.2018.08.080. Epub 2018 Aug 28.


Who should be "controls" in studies on the neurobiology of psychiatric disorders?

Boksa P, Joober R.

J Psychiatry Neurosci. 2018 Aug;43(5):292-297. No abstract available.


A NEET distinction: youths not in employment, education or training follow different pathways to illness and care in psychosis.

Iyer S, Mustafa S, Gariépy G, Shah J, Joober R, Lepage M, Malla A.

Soc Psychiatry Psychiatr Epidemiol. 2018 Dec;53(12):1401-1411. doi: 10.1007/s00127-018-1565-3. Epub 2018 Aug 9.


Effectiveness of Community Treatment Order in Patients with a First Episode of Psychosis: A Mirror-Image Study.

Levy E, Mustafa S, Naveed K, Joober R.

Can J Psychiatry. 2018 Nov;63(11):766-773. doi: 10.1177/0706743718777389. Epub 2018 Aug 5.


DRD3 Gene and ADHD: A Pharmaco-Behavioural Genetic Study.

Fageera W, Sengupta SM, Labbe A, Grizenko N, Joober R.

Neuromolecular Med. 2018 Dec;20(4):515-524. doi: 10.1007/s12017-018-8504-z. Epub 2018 Jul 26.


Gender differences in childhood trauma in first episode psychosis: Association with symptom severity over two years.

Pruessner M, King S, Vracotas N, Abadi S, Iyer S, Malla AK, Shah J, Joober R.

Schizophr Res. 2019 Mar;205:30-37. doi: 10.1016/j.schres.2018.06.043. Epub 2018 Jun 21.


Generalizing Duchenne to sad expressions with binocular rivalry and perception ratings.

Malek N, Messinger D, Gao AYL, Krumhuber E, Mattson W, Joober R, Tabbane K, Martinez-Trujillo JC.

Emotion. 2019 Mar;19(2):234-241. doi: 10.1037/emo0000410. Epub 2018 Jun 11.


Progress of negative symptoms over the initial 5 years of a first episode of psychosis - CORRIGENDUM.

Lutgens D, Joober R, Iyer S, Lepage M, Norman R, Schmitz N, Mustafa S, Abadi S, Malla A.

Psychol Med. 2018 Aug;48(11):1921-1923. doi: 10.1017/S0033291718000843. Epub 2018 May 2. No abstract available.


Mesocorticolimbic Connectivity and Volumetric Alterations in DCC Mutation Carriers.

Vosberg DE, Zhang Y, Menegaux A, Chalupa A, Manitt C, Zehntner S, Eng C, DeDuck K, Allard D, Durand F, Dagher A, Benkelfat C, Srour M, Joober R, Lepore F, Rouleau G, Théoret H, Bedell BJ, Flores C, Leyton M.

J Neurosci. 2018 May 16;38(20):4655-4665. doi: 10.1523/JNEUROSCI.3251-17.2018. Epub 2018 Apr 30.


Predictors of 'all-cause discontinuation' of initial oral antipsychotic medication in first episode psychosis.

Mustafa S, Joober R, Lepage M, Iyer S, Shah J, Malla A.

Schizophr Res. 2018 Nov;201:287-293. doi: 10.1016/j.schres.2018.04.027. Epub 2018 Apr 26.


Cultural and Contextual Adaptation of an eHealth Intervention for Youth Receiving Services for First-Episode Psychosis: Adaptation Framework and Protocol for Horyzons-Canada Phase 1.

Lal S, Gleeson J, Malla A, Rivard L, Joober R, Chandrasena R, Alvarez-Jimenez M.

JMIR Res Protoc. 2018 Apr 23;7(4):e100. doi: 10.2196/resprot.8810.


Social Determinants of Health and Preclinical Glycemic Control in Newly Diagnosed First-Episode Psychosis Patients.

Veru-Lesmes F, Rho A, King S, Joober R, Pruessner M, Malla A, Iyer SN.

Can J Psychiatry. 2018 Aug;63(8):547-556. doi: 10.1177/0706743718762097. Epub 2018 Apr 16.


Description, evaluation and scale-up potential of a model for rapid access to early intervention for psychosis.

MacDonald K, Malla A, Joober R, Shah JL, Goldberg K, Abadi S, Doyle M, Iyer SN.

Early Interv Psychiatry. 2018 Dec;12(6):1222-1228. doi: 10.1111/eip.12564. Epub 2018 Mar 26.


Corrigendum to "Therapeutic Effectiveness and Tolerability of Aripiprazole as Initial Choice of Treatment in First Episode Psychosis in an Early Intervention Service: A One-Year Outcome Study" [Schizophr. Res. 147, 120-125].

Malla A, Mustafa S, Rho A, Abadi S, Lepage M, Joober R.

Schizophr Res. 2018 Mar;193:490. doi: 10.1016/j.schres.2018.03.009. No abstract available.


Baby or bathwater? Referrals of "non-cases" in a targeted early identification intervention for psychosis.

Jordan G, Kinkaid M, Iyer SN, Joober R, Goldberg K, Malla A, Shah JL.

Soc Psychiatry Psychiatr Epidemiol. 2018 Jul;53(7):757-761. doi: 10.1007/s00127-018-1502-5. Epub 2018 Mar 14.


Progress of negative symptoms over the initial 5 years of a first episode of psychosis.

Lutgens D, Joober R, Iyer S, Lepage M, Norman R, Schmitz N, Mustafa S, Abadi S, Malla A.

Psychol Med. 2019 Jan;49(1):66-74. doi: 10.1017/S003329171800048X. Epub 2018 Mar 14. Erratum in: Psychol Med. 2018 Aug;48(11):1921-1923.


Youth Mental Health Should Be a Top Priority for Health Care in Canada.

Malla A, Shah J, Iyer S, Boksa P, Joober R, Andersson N, Lal S, Fuhrer R.

Can J Psychiatry. 2018 Apr;63(4):216-222. doi: 10.1177/0706743718758968. Epub 2018 Mar 11.


Healthy versus Entorhinal Cortical Atrophy Identification in Asymptomatic APOE4 Carriers at Risk for Alzheimer's Disease.

Konishi K, Joober R, Poirier J, MacDonald K, Chakravarty M, Patel R, Breitner J, Bohbot VD.

J Alzheimers Dis. 2018;61(4):1493-1507. doi: 10.3233/JAD-170540.


Pathways to functional outcomes following a first episode of psychosis: The roles of premorbid adjustment, verbal memory and symptom remission.

Jordan G, Veru F, Lepage M, Joober R, Malla A, Iyer SN.

Aust N Z J Psychiatry. 2018 Aug;52(8):793-803. doi: 10.1177/0004867417747401. Epub 2017 Dec 17.


DRD4 exon 3 genotype and ADHD: Randomised pharmacodynamic investigation of treatment response to methylphenidate.

Naumova D, Grizenko N, Sengupta SM, Joober R.

World J Biol Psychiatry. 2017 Dec 15:1-10. doi: 10.1080/15622975.2017.1410221. [Epub ahead of print]


Treatment of ADHD in patients with bipolar disorder.

Girard R, Joober R.

J Psychiatry Neurosci. 2017 Nov;42(6):E11-E12. No abstract available.


The value of a skeptical approach to neurosciences in psychiatric training and practice.

Traicu A, Joober R.

J Psychiatry Neurosci. 2017 Nov;42(6):363-365. No abstract available.


Comparing three-year extension of early intervention service to regular care following two years of early intervention service in first-episode psychosis: a randomized single blind clinical trial.

Malla A, Joober R, Iyer S, Norman R, Schmitz N, Brown T, Lutgens D, Jarvis E, Margolese HC, Casacalenda N, Abdel-Baki A, Latimer E, Mustafa S, Abadi S.

World Psychiatry. 2017 Oct;16(3):278-286. doi: 10.1002/wps.20456.


Differential Associations between Cortical Thickness and Striatal Dopamine in Treatment-Naïve Adults with ADHD vs. Healthy Controls.

Cherkasova MV, Faridi N, Casey KF, Larcher K, O'Driscoll GA, Hechtman L, Joober R, Baker GB, Palmer J, Evans AC, Dagher A, Benkelfat C, Leyton M.

Front Hum Neurosci. 2017 Aug 22;11:421. doi: 10.3389/fnhum.2017.00421. eCollection 2017.

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