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Items: 1 to 50 of 90

1.

Novel Concept of CD4-Mediated Activation of Regulatory T Cells for the Treatment of Graft-Versus-Host Disease.

Schlöder J, Berges C, Tuettenberg A, Jonuleit H.

Front Immunol. 2017 Nov 8;8:1495. doi: 10.3389/fimmu.2017.01495. eCollection 2017. Review.

2.

TCR signalling network organization at the immunological synapses of murine regulatory T cells.

van Ham M, Teich R, Philipsen L, Niemz J, Amsberg N, Wissing J, Nimtz M, Gröbe L, Kliche S, Thiel N, Klawonn F, Hubo M, Jonuleit H, Reichardt P, Müller AJ, Huehn J, Jänsch L.

Eur J Immunol. 2017 Dec;47(12):2043-2058. doi: 10.1002/eji.201747041. Epub 2017 Sep 12.

PMID:
28833060
3.

Immunization with a Synthetic Human MUC1 Glycopeptide Vaccine against Tumor-Associated MUC1 Breaks Tolerance in Human MUC1 Transgenic Mice.

Stergiou N, Glaffig M, Jonuleit H, Schmitt E, Kunz H.

ChemMedChem. 2017 Sep 7;12(17):1424-1428. doi: 10.1002/cmdc.201700387. Epub 2017 Aug 7.

PMID:
28675699
4.

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha.

Kienzle A, Kurch S, Schlöder J, Berges C, Ose R, Schupp J, Tuettenberg A, Weiss H, Schultze J, Winzen S, Schinnerer M, Koynov K, Mezger M, Haass NK, Tremel W, Jonuleit H.

Adv Healthc Mater. 2017 Jul;6(13). doi: 10.1002/adhm.201700012. Epub 2017 May 29.

PMID:
28557249
5.

Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor 7.

Hellmuth I, Freund I, Schlöder J, Seidu-Larry S, Thüring K, Slama K, Langhanki J, Kaloyanova S, Eigenbrod T, Krumb M, Röhm S, Peneva K, Opatz T, Jonuleit H, Dalpke AH, Helm M.

Front Immunol. 2017 Mar 24;8:312. doi: 10.3389/fimmu.2017.00312. eCollection 2017.

6.

Dimethyl Fumarate Therapy Significantly Improves the Responsiveness of T Cells in Multiple Sclerosis Patients for Immunoregulation by Regulatory T Cells.

Schlöder J, Berges C, Luessi F, Jonuleit H.

Int J Mol Sci. 2017 Jan 28;18(2). pii: E271. doi: 10.3390/ijms18020271.

7.

Treg cells as potential cellular targets for functionalized nanoparticles in cancer therapy.

Jonuleit H, Bopp T, Becker C.

Nanomedicine (Lond). 2016 Oct;11(20):2699-2709. Epub 2016 Sep 21. Review.

PMID:
27654070
8.

Pillars Article: Induction of Tolerance by IL-10-Treated Dendritic Cells. J. Immunol. 1997. 159: 4772-4780.

Steinbrink K, Wölfl M, Jonuleit H, Knop J, Enk AH.

J Immunol. 2016 Sep 1;197(5):1547-55. No abstract available.

9.

A key role of GARP in the immune suppressive tumor microenvironment.

Hahn SA, Neuhoff A, Landsberg J, Schupp J, Eberts D, Leukel P, Bros M, Weilbaecher M, Schuppan D, Grabbe S, Tueting T, Lennerz V, Sommer C, Jonuleit H, Tuettenberg A.

Oncotarget. 2016 Jul 12;7(28):42996-43009. doi: 10.18632/oncotarget.9598.

10.

Editorial: Current Concepts of Cellular and Biological Drugs to Modulate Regulatory T Cell Activity in the Clinic.

Jonuleit H, Bopp T.

Front Immunol. 2016 Apr 14;7:141. doi: 10.3389/fimmu.2016.00141. eCollection 2016. No abstract available.

11.

GARP inhibits allergic airway inflammation in a humanized mouse model.

Meyer-Martin H, Hahn SA, Beckert H, Belz C, Heinz A, Jonuleit H, Becker C, Taube C, Korn S, Buhl R, Reuter S, Tuettenberg A.

Allergy. 2016 Sep;71(9):1274-83. doi: 10.1111/all.12883. Epub 2016 Apr 1.

PMID:
26990894
12.

Kinome Profiling of Regulatory T Cells: A Closer Look into a Complex Intracellular Network.

Tuettenberg A, Hahn SA, Mazur J, Gerhold-Ay A, Scholma J, Marg I, Ulges A, Satoh K, Bopp T, Joore J, Jonuleit H.

PLoS One. 2016 Feb 16;11(2):e0149193. doi: 10.1371/journal.pone.0149193. eCollection 2016.

13.

Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells.

Trinschek B, Luessi F, Gross CC, Wiendl H, Jonuleit H.

Int J Mol Sci. 2015 Jul 17;16(7):16330-46. doi: 10.3390/ijms160716330.

14.

FTY720 (fingolimod) treatment tips the balance towards less immunogenic antigen-presenting cells in patients with multiple sclerosis.

Luessi F, Kraus S, Trinschek B, Lerch S, Ploen R, Paterka M, Roberg T, Poisa-Beiro L, Klotz L, Wiendl H, Bopp T, Jonuleit H, Jolivel V, Zipp F, Witsch E.

Mult Scler. 2015 Dec;21(14):1811-22. doi: 10.1177/1352458515574895. Epub 2015 Mar 2.

PMID:
25732840
15.

Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.

Ulges A, Klein M, Reuter S, Gerlitzki B, Hoffmann M, Grebe N, Staudt V, Stergiou N, Bohn T, Brühl TJ, Muth S, Yurugi H, Rajalingam K, Bellinghausen I, Tuettenberg A, Hahn S, Reißig S, Haben I, Zipp F, Waisman A, Probst HC, Beilhack A, Buchou T, Filhol-Cochet O, Boldyreff B, Breloer M, Jonuleit H, Schild H, Schmitt E, Bopp T.

Nat Immunol. 2015 Mar;16(3):267-75. doi: 10.1038/ni.3083. Epub 2015 Jan 19.

PMID:
25599562
16.

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway.

Helling B, König M, Dälken B, Engling A, Krömer W, Heim K, Wallmeier H, Haas J, Wildemann B, Fritz B, Jonuleit H, Kubach J, Dingermann T, Radeke HH, Osterroth F, Uherek C, Czeloth N, Schüttrumpf J.

Immunol Cell Biol. 2015 Apr;93(4):396-405. doi: 10.1038/icb.2014.102. Epub 2014 Dec 16.

17.

IgG1 anti-epidermal growth factor receptor antibodies induce CD8-dependent antitumor activity.

Kubach J, Hubo M, Amendt C, Stroh C, Jonuleit H.

Int J Cancer. 2015 Feb 15;136(4):821-30. doi: 10.1002/ijc.29037. Epub 2014 Jun 26.

18.

Cladribine exerts an immunomodulatory effect on human and murine dendritic cells.

Kraus SH, Luessi F, Trinschek B, Lerch S, Hubo M, Poisa-Beiro L, Paterka M, Jonuleit H, Zipp F, Jolivel V.

Int Immunopharmacol. 2014 Feb;18(2):347-57. doi: 10.1016/j.intimp.2013.11.027. Epub 2013 Dec 5.

PMID:
24316255
19.

Kinetics of IL-6 production defines T effector cell responsiveness to regulatory T cells in multiple sclerosis.

Trinschek B, Luessi F, Haas J, Wildemann B, Zipp F, Wiendl H, Becker C, Jonuleit H.

PLoS One. 2013 Oct 14;8(10):e77634. doi: 10.1371/journal.pone.0077634. eCollection 2013. Erratum in: PLoS One. 2013;8(11). doi: 10.1371/annotation/0e76c09e-75b2-493a-90fd-cda3187a0888. Lüssi, Felix [corrected to Luessi, Felix].

20.

Soluble GARP has potent antiinflammatory and immunomodulatory impact on human CD4⁺ T cells.

Hahn SA, Stahl HF, Becker C, Correll A, Schneider FJ, Tuettenberg A, Jonuleit H.

Blood. 2013 Aug 15;122(7):1182-91. doi: 10.1182/blood-2012-12-474478. Epub 2013 Jul 1.

21.

Subclinical CNS inflammation as response to a myelin antigen in humanized mice.

Zayoud M, El Malki K, Frauenknecht K, Trinschek B, Kloos L, Karram K, Wanke F, Georgescu J, Hartwig UF, Sommer C, Jonuleit H, Waisman A, Kurschus FC.

J Neuroimmune Pharmacol. 2013 Sep;8(4):1037-47. doi: 10.1007/s11481-013-9466-4. Epub 2013 May 3.

PMID:
23640521
22.

Costimulatory molecules on immunogenic versus tolerogenic human dendritic cells.

Hubo M, Trinschek B, Kryczanowsky F, Tuettenberg A, Steinbrink K, Jonuleit H.

Front Immunol. 2013 Apr 3;4:82. doi: 10.3389/fimmu.2013.00082. eCollection 2013.

23.

Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis.

Jolivel V, Luessi F, Masri J, Kraus SH, Hubo M, Poisa-Beiro L, Klebow S, Paterka M, Yogev N, Tumani H, Furlan R, Siffrin V, Jonuleit H, Zipp F, Waisman A.

Brain. 2013 Apr;136(Pt 4):1048-66. doi: 10.1093/brain/awt023. Epub 2013 Mar 20.

PMID:
23518712
24.

Synthesis of maleimide-functionalyzed HPMA-copolymers and in vitro characterization of the aRAGE- and human immunoglobulin (huIgG)-polymer conjugates.

Tappertzhofen K, Metz VV, Hubo M, Barz M, Postina R, Jonuleit H, Zentel R.

Macromol Biosci. 2013 Feb;13(2):203-14. doi: 10.1002/mabi.201200344. Epub 2012 Dec 13.

PMID:
23239639
25.

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.

Vaeth M, Schliesser U, Müller G, Reissig S, Satoh K, Tuettenberg A, Jonuleit H, Waisman A, Müller MR, Serfling E, Sawitzki BS, Berberich-Siebelt F.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16258-63. doi: 10.1073/pnas.1203870109. Epub 2012 Sep 18.

26.

Plasmacytoid dendritic cells are inefficient in activation of human regulatory T cells.

Hubo M, Jonuleit H.

PLoS One. 2012;7(8):e44056. doi: 10.1371/journal.pone.0044056. Epub 2012 Aug 29.

27.

Boosting regulatory T cell function by CD4 stimulation enters the clinic.

Becker C, Bopp T, Jonuleit H.

Front Immunol. 2012 Jun 18;3:164. doi: 10.3389/fimmu.2012.00164. eCollection 2012.

28.

Fulfilling the dream: tolerogenic dendritic cells to treat multiple sclerosis.

Gross CC, Jonuleit H, Wiendl H.

Eur J Immunol. 2012 Mar;42(3):569-72. doi: 10.1002/eji.201242402.

29.

Allergen-induced IgE-dependent gut inflammation in a human PBMC-engrafted murine model of allergy.

Weigmann B, Schughart N, Wiebe C, Sudowe S, Lehr HA, Jonuleit H, Vogel L, Becker C, Neurath MF, Grabbe S, Saloga J, Bellinghausen I.

J Allergy Clin Immunol. 2012 Apr;129(4):1126-35. doi: 10.1016/j.jaci.2011.11.036. Epub 2012 Jan 10.

PMID:
22236728
30.

CD4-mediated regulatory T-cell activation inhibits the development of disease in a humanized mouse model of allergic airway disease.

Martin H, Reuter S, Dehzad N, Heinz A, Bellinghausen I, Saloga J, Haasler I, Korn S, Jonuleit H, Buhl R, Becker C, Taube C.

J Allergy Clin Immunol. 2012 Feb;129(2):521-8, 528.e1-7. doi: 10.1016/j.jaci.2011.09.038. Epub 2011 Nov 10.

PMID:
22078574
31.

Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction.

Wenzel P, Knorr M, Kossmann S, Stratmann J, Hausding M, Schuhmacher S, Karbach SH, Schwenk M, Yogev N, Schulz E, Oelze M, Grabbe S, Jonuleit H, Becker C, Daiber A, Waisman A, Münzel T.

Circulation. 2011 Sep 20;124(12):1370-81. doi: 10.1161/CIRCULATIONAHA.111.034470. Epub 2011 Aug 29.

PMID:
21875910
32.

Interferon-α abrogates tolerance induction by human tolerogenic dendritic cells.

Bacher N, Graulich E, Jonuleit H, Grabbe S, Steinbrink K.

PLoS One. 2011;6(7):e22763. doi: 10.1371/journal.pone.0022763. Epub 2011 Jul 27.

33.

Immune regulation by dendritic cells and T cells--basic science, diagnostic, and clinical application.

Tuettenberg A, Becker C, Correll A, Steinbrink K, Jonuleit H.

Clin Lab. 2011;57(1-2):1-12. Review.

PMID:
21391459
34.

Research in practice: Regulatory T cells - targets for therapeutic approaches?

Jonuleit H, Tuettenberg A, Steinbrink K; Working Group Dermatologic Research (Abeitsgemeinschaft Dermatologische Forschung, ADF).

J Dtsch Dermatol Ges. 2011 Jan;9(1):8-11. doi: 10.1111/j.1610-0387.2010.07503.x. Epub 2010 Sep 7. Review. English, German.

PMID:
21166772
35.

Human primary dendritic cell subsets differ in their IL-12 release in response to Leishmania major infection.

Zahn S, Kirschsiefen P, Jonuleit H, Steinbrink K, Von Stebut E.

Exp Dermatol. 2010 Oct;19(10):924-6. doi: 10.1111/j.1600-0625.2010.01149.x. Epub 2010 Aug 12.

PMID:
20707811
36.

Large scale preparation of human MHC class II+ integrin beta(1)+ Tregs.

Bonnin B, Correll A, Swiatek-de Lange M, Lenter M, Schneider FJ, Wijdenes J, Jonuleit H, Becker C.

J Immunol Methods. 2010 Aug 31;360(1-2):96-102. doi: 10.1016/j.jim.2010.06.014. Epub 2010 Jun 25.

PMID:
20599542
37.
38.

Generation of monoclonal antibodies against human regulatory T cells.

Becker C, Hoschützky H, Rist W, Lenter M, Schneider FJ, Jonuleit H.

J Immunol Methods. 2010 Feb 28;353(1-2):62-70. doi: 10.1016/j.jim.2010.01.002. Epub 2010 Jan 22.

PMID:
20096700
39.

CD40 signalling induces IL-10-producing, tolerogenic dendritic cells.

Tuettenberg A, Fondel S, Steinbrink K, Enk AH, Jonuleit H.

Exp Dermatol. 2010 Jan;19(1):44-53. doi: 10.1111/j.1600-0625.2009.00975.x. Epub 2009 Nov 2.

40.

miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression.

Stahl HF, Fauti T, Ullrich N, Bopp T, Kubach J, Rust W, Labhart P, Alexiadis V, Becker C, Hafner M, Weith A, Lenter MC, Jonuleit H, Schmitt E, Mennerich D.

PLoS One. 2009 Sep 24;4(9):e7158. doi: 10.1371/journal.pone.0007158.

41.

Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells.

Becker C, Taube C, Bopp T, Becker C, Michel K, Kubach J, Reuter S, Dehzad N, Neurath MF, Reifenberg K, Schneider FJ, Schmitt E, Jonuleit H.

Blood. 2009 Aug 6;114(6):1263-9. doi: 10.1182/blood-2009-02-206730. Epub 2009 May 13.

42.

The role of ICOS in directing T cell responses: ICOS-dependent induction of T cell anergy by tolerogenic dendritic cells.

Tuettenberg A, Huter E, Hubo M, Horn J, Knop J, Grimbacher B, Kroczek RA, Stoll S, Jonuleit H.

J Immunol. 2009 Mar 15;182(6):3349-56. doi: 10.4049/jimmunol.0802733.

43.

Myeloid dendritic cell: From sentinel of immunity to key player of peripheral tolerance?

Steinbrink K, Mahnke K, Grabbe S, Enk AH, Jonuleit H.

Hum Immunol. 2009 May;70(5):289-93. doi: 10.1016/j.humimm.2009.02.003. Epub 2009 Feb 13. Review.

PMID:
19217922
44.

Regulatory T cells--the renaissance of the suppressor T cells.

Bopp T, Jonuleit H, Schmitt E.

Ann Med. 2007;39(5):322-34. Review.

PMID:
17701475
45.

Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression.

Bopp T, Becker C, Klein M, Klein-Hessling S, Palmetshofer A, Serfling E, Heib V, Becker M, Kubach J, Schmitt S, Stoll S, Schild H, Staege MS, Stassen M, Jonuleit H, Schmitt E.

J Exp Med. 2007 Jun 11;204(6):1303-10. Epub 2007 May 14.

46.

Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function.

Kubach J, Lutter P, Bopp T, Stoll S, Becker C, Huter E, Richter C, Weingarten P, Warger T, Knop J, Müllner S, Wijdenes J, Schild H, Schmitt E, Jonuleit H.

Blood. 2007 Sep 1;110(5):1550-8. Epub 2007 May 14.

47.

CD4-mediated functional activation of human CD4+CD25+ regulatory T cells.

Becker C, Kubach J, Wijdenes J, Knop J, Jonuleit H.

Eur J Immunol. 2007 May;37(5):1217-23.

48.

Dendritic cell-based immunotherapy of malignant melanoma: success and limitations.

Tuettenberg A, Schmitt E, Knop J, Jonuleit H.

J Dtsch Dermatol Ges. 2007 Mar;5(3):190-6. Review. English, German.

PMID:
17338793
49.

Oxymetazoline modulates proinflammatory cytokines and the T-cell stimulatory capacity of dendritic cells.

Tuettenberg A, Koelsch S, Knop J, Jonuleit H.

Exp Dermatol. 2007 Mar;16(3):171-8.

PMID:
17286808
50.

Interaction of TLR2 and TLR4 ligands with the N-terminal domain of Gp96 amplifies innate and adaptive immune responses.

Warger T, Hilf N, Rechtsteiner G, Haselmayer P, Carrick DM, Jonuleit H, von Landenberg P, Rammensee HG, Nicchitta CV, Radsak MP, Schild H.

J Biol Chem. 2006 Aug 11;281(32):22545-53. Epub 2006 Jun 5.

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