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Items: 22

1.

A cellular census of human lungs identifies novel cell states in health and in asthma.

Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA.

Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17.

PMID:
31209336
2.

Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD.

Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M.

Eur Respir J. 2019 Apr 25;53(4). pii: 1801202. doi: 10.1183/13993003.01202-2018. Print 2019 Apr.

PMID:
30846474
3.

Pro-inflammatory effects of extracellular Hsp70 and cigarette smoke in primary airway epithelial cells from COPD patients.

Hulina-Tomašković A, Heijink IH, Jonker MR, Somborac-Bačura A, Grdić Rajković M, Rumora L.

Biochimie. 2019 Jan;156:47-58. doi: 10.1016/j.biochi.2018.09.010. Epub 2018 Sep 27.

PMID:
30268700
4.

Effects of fluticasone propionate and budesonide on the expression of immune defense genes in bronchial epithelial cells.

van den Berge M, Jonker MR, Miller-Larsson A, Postma DS, Heijink IH.

Pulm Pharmacol Ther. 2018 Jun;50:47-56. doi: 10.1016/j.pupt.2018.04.002. Epub 2018 Apr 5.

PMID:
29627483
5.

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression.

Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, Boersma WG, Wielders P, van den Elshout F, Mansour K, Spira A, Lenburg ME, Guryev V, Postma DS, van den Berge M.

Respir Res. 2017 Dec 21;18(1):213. doi: 10.1186/s12931-017-0696-5.

6.

Increased neutrophil expression of pattern recognition receptors during COPD exacerbations.

Pouwels SD, van Geffen WH, Jonker MR, Kerstjens HA, Nawijn MC, Heijink IH.

Respirology. 2017 Feb;22(2):401-404. doi: 10.1111/resp.12912. Epub 2016 Sep 27.

PMID:
27679416
7.

Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD.

Heijink IH, de Bruin HG, Dennebos R, Jonker MR, Noordhoek JA, Brandsma CA, van den Berge M, Postma DS.

Eur Respir J. 2016 Aug;48(2):504-15. doi: 10.1183/13993003.01541-2015. Epub 2016 Apr 28.

8.

Budesonide and fluticasone propionate differentially affect the airway epithelial barrier.

Heijink IH, Jonker MR, de Vries M, van Oosterhout AJ, Telenga E, Ten Hacken NH, Postma DS, van den Berge M.

Respir Res. 2016 Jan 6;17:2. doi: 10.1186/s12931-015-0318-z.

9.

Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure.

de Vries M, Hesse L, Jonker MR, van den Berge M, van Oosterhout AJ, Heijink IH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1344-53. doi: 10.1152/ajplung.00043.2015. Epub 2015 Oct 9.

10.

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD.

Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C, Tsitsiou E, Caramori G, Contoli M, Casolari P, Monaco F, Andò F, Speciale G, Kilty I, Chung KF, Papi A, Lindsay MA, Ten Hacken NH, van den Berge M, Timens W, Barnes PJ, van Oosterhout AJ, Adcock IM, Kirkham PA, Heijink IH.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1112-23. doi: 10.1152/ajplung.00077.2015. Epub 2015 Aug 28.

11.

ADAM10 mediates the house dust mite-induced release of chemokine ligand CCL20 by airway epithelium.

Post S, Rozeveld D, Jonker MR, Bischoff R, van Oosterhout AJ, Heijink IH.

Allergy. 2015 Dec;70(12):1545-52. doi: 10.1111/all.12730. Epub 2015 Sep 11.

PMID:
26296735
12.

A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD.

Brandsma CA, van den Berge M, Postma DS, Jonker MR, Brouwer S, Paré PD, Sin DD, Bossé Y, Laviolette M, Karjalainen J, Fehrmann RS, Nickle DC, Hao K, Spanjer AI, Timens W, Franke L.

Thorax. 2015 Jan;70(1):21-32. doi: 10.1136/thoraxjnl-2014-205091. Epub 2014 Jul 2.

PMID:
24990664
13.

Glucocorticoids induce the production of the chemoattractant CCL20 in airway epithelium.

Zijlstra GJ, Fattahi F, Rozeveld D, Jonker MR, Kliphuis NM, van den Berge M, Hylkema MN, ten Hacken NH, van Oosterhout AJ, Heijink IH.

Eur Respir J. 2014 Aug;44(2):361-70. doi: 10.1183/09031936.00209513. Epub 2014 Mar 13.

14.

Differential effects of fluticasone on extracellular matrix production by airway and parenchymal fibroblasts in severe COPD.

Brandsma CA, Timens W, Jonker MR, Rutgers B, Noordhoek JA, Postma DS.

Am J Physiol Lung Cell Mol Physiol. 2013 Oct 15;305(8):L582-9. doi: 10.1152/ajplung.00152.2013. Epub 2013 Aug 30.

15.

House dust mite-induced calcium signaling instigates epithelial barrier dysfunction and CCL20 production.

Post S, Nawijn MC, Jonker MR, Kliphuis N, van den Berge M, van Oosterhout AJ, Heijink IH.

Allergy. 2013 Sep;68(9):1117-25. doi: 10.1111/all.12202. Epub 2013 Aug 5.

PMID:
23915187
16.

Activation of WNT/β-catenin signaling in pulmonary fibroblasts by TGF-β₁ is increased in chronic obstructive pulmonary disease.

Baarsma HA, Spanjer AI, Haitsma G, Engelbertink LH, Meurs H, Jonker MR, Timens W, Postma DS, Kerstjens HA, Gosens R.

PLoS One. 2011;6(9):e25450. doi: 10.1371/journal.pone.0025450. Epub 2011 Sep 30.

17.

Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD.

Zandvoort A, Postma DS, Jonker MR, Noordhoek JA, Vos JT, Timens W.

Respir Res. 2008 Dec 16;9:83. doi: 10.1186/1465-9921-9-83.

18.

Effects of different immunosuppressive regimens on regulatory T-cells in noninflamed colon of liver transplant recipients.

Verdonk RC, Haagsma EB, Jonker MR, Bok LI, Zandvoort JH, Kleibeuker JH, Faber KN, Dijkstra G.

Inflamm Bowel Dis. 2007 Jun;13(6):703-9.

PMID:
17230494
19.

Altered expression of the Smad signalling pathway: implications for COPD pathogenesis.

Zandvoort A, Postma DS, Jonker MR, Noordhoek JA, Vos JT, van der Geld YM, Timens W.

Eur Respir J. 2006 Sep;28(3):533-41. Epub 2006 May 17.

20.

High ICAM-1 gene expression in pulmonary fibroblasts of COPD patients: a reflection of an enhanced immunological function.

Zandvoort A, van der Geld YM, Jonker MR, Noordhoek JA, Vos JT, Wesseling J, Kauffman HF, Timens W, Postma DS.

Eur Respir J. 2006 Jul;28(1):113-22. Epub 2006 Apr 12.

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