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Items: 1 to 50 of 182

1.

Levels of α- and β-synuclein regulate cellular susceptibility to toxicity from α-synuclein oligomers.

Angelova DM, Jones HBL, Brown DR.

FASEB J. 2018 Feb;32(2):995-1006. doi: 10.1096/fj.201700675R. Epub 2018 Jan 4.

PMID:
29054856
2.

A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis.

Jones HBL, Wells SA, Prentice EJ, Kwok A, Liang LL, Arcus VL, Pudney CR.

FEBS J. 2017 Sep;284(17):2829-2842. doi: 10.1111/febs.14152. Epub 2017 Jul 25.

3.

HIV/AIDS KNOWLEDGE AND PRIOR TESTING AT 'AFRICA GOAL' OUTREACH EVENTS IN EAST AND SOUTHERN AFRICA.

Jones HB, Gross R.

Afr J Infect Dis. 2016 May 1;10(2):118-120. doi: 10.21010/ajid.v10i2.7. eCollection 2016.

4.

Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice.

Pickup K, Martin S, Partridge EA, Jones HB, Wills J, Schulz-Utermoehl T, McCarthy A, Rodrigues A, Page C, Ratcliffe K, Sarda S, Wilson ID.

Arch Toxicol. 2017 Jul;91(7):2643-2653. doi: 10.1007/s00204-016-1894-5. Epub 2016 Nov 28.

5.

Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN™) mice dosed orally with fenclozic acid.

Akingbasote JA, Foster AJ, Jones HB, David R, Gooderham NJ, Wilson ID, Kenna JG.

Toxicol Res (Camb). 2016 Nov 9;6(1):81-88. doi: 10.1039/c6tx00376a. eCollection 2017 Jan 1.

6.

Spa47 is an oligomerization-activated type three secretion system (T3SS) ATPase from Shigella flexneri.

Burgess JL, Jones HB, Kumar P, Toth RT 4th, Middaugh CR, Antony E, Dickenson NE.

Protein Sci. 2016 May;25(5):1037-48. doi: 10.1002/pro.2917. Epub 2016 Mar 22.

7.

Quantifying interspecific variation in dispersal ability of noctuid moths using an advanced tethered flight technique.

Jones HB, Lim KS, Bell JR, Hill JK, Chapman JW.

Ecol Evol. 2015 Dec 15;6(1):181-90. doi: 10.1002/ece3.1861. eCollection 2016 Jan.

8.

Evidence for a pervasive 'idling-mode' activity template in flying and pedestrian insects.

Reynolds AM, Jones HB, Hill JK, Pearson AJ, Wilson K, Wolf S, Lim KS, Reynolds DR, Chapman JW.

R Soc Open Sci. 2015 May 20;2(5):150085. doi: 10.1098/rsos.150085. eCollection 2015 May.

9.

Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice.

Akingbasote JA, Foster AJ, Wilson I, Sarda S, Jones HB, Kenna JG.

Arch Toxicol. 2016 Apr;90(4):853-62. doi: 10.1007/s00204-015-1505-x. Epub 2015 Mar 28.

PMID:
25820915
10.

Pharmacological inhibition of DGAT1 induces sebaceous gland atrophy in mouse and dog skin while overt alopecia is restricted to the mouse.

Floettmann E, Lees D, Seeliger F, Jones HB.

Toxicol Pathol. 2015 Apr;43(3):376-83. doi: 10.1177/0192623314545657. Epub 2014 Aug 11.

PMID:
25112279
11.

Chronic glucokinase activator treatment at clinically translatable exposures gives durable glucose lowering in two animal models of type 2 diabetes.

Baker DJ, Wilkinson GP, Atkinson AM, Jones HB, Coghlan M, Charles AD, Leighton B.

Br J Pharmacol. 2014 Apr;171(7):1642-54.

12.

Myocardial steatosis and necrosis in atria and ventricles of rats given pyruvate dehydrogenase kinase inhibitors.

Jones HB, Reens J, Johnson E, Brocklehurst S, Slater I.

Toxicol Pathol. 2014 Dec;42(8):1250-66. doi: 10.1177/0192623314530195. Epub 2014 Apr 17.

PMID:
24742628
13.

Islets of Langerhans from prohormone convertase-2 knockout mice show α-cell hyperplasia and tumorigenesis with elevated α-cell neogenesis.

Jones HB, Reens J, Brocklehurst SR, Betts CJ, Bickerton S, Bigley AL, Jenkins RP, Whalley NM, Morgan D, Smith DM.

Int J Exp Pathol. 2014 Feb;95(1):29-48. doi: 10.1111/iep.12066.

14.

The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse.

Pickup K, Wills J, Rodrigues A, Jones HB, Page C, Martin S, Sarda S, Wilson I.

Xenobiotica. 2014 Jan;44(2):164-73. doi: 10.3109/00498254.2013.866299. Epub 2013 Dec 10.

PMID:
24320884
15.

Papillary carcinoma within a thyroglossal duct cyst: significance of a central solid component on ultrasound imaging.

Aculate NR, Jones HB, Bansal A, Ho MW.

Br J Oral Maxillofac Surg. 2014 Mar;52(3):277-8. doi: 10.1016/j.bjoms.2013.10.003. Epub 2013 Nov 5.

PMID:
24210780
16.

Tissue expression and correlation of a panel of urinary biomarkers following cisplatin-induced kidney injury.

Wadey RM, Pinches MG, Jones HB, Riccardi D, Price SA.

Toxicol Pathol. 2014;42(3):591-602. doi: 10.1177/0192623313492044. Epub 2013 Jul 3.

PMID:
23823703
17.

Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition.

Ulloa JL, Stahl S, Yates J, Woodhouse N, Kenna JG, Jones HB, Waterton JC, Hockings PD.

NMR Biomed. 2013 Oct;26(10):1258-70. doi: 10.1002/nbm.2946. Epub 2013 Apr 7.

18.

ACAT-selective and nonselective DGAT1 inhibition: adrenocortical effects--a cross-species comparison.

Floettmann JE, Buckett LK, Turnbull AV, Smith T, Hallberg C, Birch A, Lees D, Jones HB.

Toxicol Pathol. 2013;41(7):941-50. doi: 10.1177/0192623313477753. Epub 2013 Feb 20.

PMID:
23427273
19.
21.

Evaluation of novel renal biomarkers with a cisplatin model of kidney injury: gender and dosage differences.

Pinches M, Betts C, Bickerton S, Burdett L, Thomas H, Derbyshire N, Jones HB, Moores M.

Toxicol Pathol. 2012 Apr;40(3):522-33. doi: 10.1177/0192623311432438.

PMID:
22491933
22.

The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: application to the metabolism of diclofenac.

Pickup K, Gavin A, Jones HB, Karlsson E, Page C, Ratcliffe K, Sarda S, Schulz-Utermoehl T, Wilson I.

Xenobiotica. 2012 Feb;42(2):195-205. doi: 10.3109/00498254.2011.607196. Epub 2011 Sep 28.

PMID:
21955249
23.

Diabetic nephropathy and long-term treatment effects of rosiglitazone and enalapril in obese ZSF1 rats.

Bilan VP, Salah EM, Bastacky S, Jones HB, Mayers RM, Zinker B, Poucher SM, Tofovic SP.

J Endocrinol. 2011 Sep;210(3):293-308. doi: 10.1530/JOE-11-0122. Epub 2011 Jun 16.

PMID:
21680617
24.

Outcome following surgical treatment for regional metastases from cutaneous cancers of the head and neck in patients aged 80 and over.

Khandavilli SD, Lloyd CJ, Jones HB.

Ann R Coll Surg Engl. 2011 Apr;93(3):223-4. doi: 10.1308/003588411X563394.

25.
26.

The novel sodium glucose transporter 2 inhibitor dapagliflozin sustains pancreatic function and preserves islet morphology in obese, diabetic rats.

Macdonald FR, Peel JE, Jones HB, Mayers RM, Westgate L, Whaley JM, Poucher SM.

Diabetes Obes Metab. 2010 Nov;12(11):1004-12. doi: 10.1111/j.1463-1326.2010.01291.x.

PMID:
20880347
27.

Variation in characteristics of islets of Langerhans in insulin-resistant, diabetic and non-diabetic-rat strains.

Jones HB, Nugent D, Jenkins R.

Int J Exp Pathol. 2010 Jun;91(3):288-301. doi: 10.1111/j.1365-2613.2010.00713.x. Epub 2010 Apr 1.

28.

Prolonged inhibition of glycogen phosphorylase in livers of Zucker Diabetic Fatty rats models human glycogen storage diseases.

Floettmann E, Gregory L, Teague J, Myatt J, Hammond C, Poucher SM, Jones HB.

Toxicol Pathol. 2010 Apr;38(3):393-401. doi: 10.1177/0192623310362707. Epub 2010 Mar 9.

PMID:
20215584
29.

A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders.

Sakurai T, Reichert J, Hoffman EJ, Cai G, Jones HB, Faham M, Buxbaum JD.

Autism Res. 2008 Aug;1(4):251-7. doi: 10.1002/aur.30.

30.

Effect of chronic phenobarbitone administration on liver tumour formation in the C57BL/10J mouse.

Jones HB, Orton TC, Lake BG.

Food Chem Toxicol. 2009 Jun;47(6):1333-40. doi: 10.1016/j.fct.2009.03.014. Epub 2009 Mar 17.

PMID:
19298838
31.

Cellular and histopathological changes in the infrapatellar fat pad in the monoiodoacetate model of osteoarthritis pain.

Clements KM, Ball AD, Jones HB, Brinckmann S, Read SJ, Murray F.

Osteoarthritis Cartilage. 2009 Jun;17(6):805-12. doi: 10.1016/j.joca.2008.11.002. Epub 2008 Nov 12.

32.

The impact of lymphovascular invasion on survival in oral carcinoma.

Jones HB, Sykes A, Bayman N, Sloan P, Swindell R, Patel M, Musgrove B.

Oral Oncol. 2009 Jan;45(1):10-5. doi: 10.1016/j.oraloncology.2008.03.009. Epub 2008 Jul 11.

PMID:
18620889
33.

A review of islet of Langerhans degeneration in rodent models of type 2 diabetes.

Nugent DA, Smith DM, Jones HB.

Toxicol Pathol. 2008 Jun;36(4):529-51. doi: 10.1177/0192623308318209. Epub 2008 May 8. Review.

PMID:
18467681
35.

Current status and future directions for diagnostic markers of drug-induced vascular injury.

Brott DA, Jones HB, Gould S, Valentin JP, Evans G, Richardson RJ, Louden C.

Cancer Biomark. 2005;1(1):15-28. Review.

PMID:
17192029
36.

Pairwise linkage disequilibrium under disease models.

Schrodi SJ, Garcia VE, Rowland C, Jones HB.

Eur J Hum Genet. 2007 Feb;15(2):212-20. Epub 2006 Nov 15.

37.

Interesting case: Spontaneous exfoliation of an upper central incisor through the nasal floor.

Jones HB, Whitley SP, Morelli G, Tuffin JR.

Br J Oral Maxillofac Surg. 2006 Dec;44(6):500. Epub 2006 May 3. No abstract available.

PMID:
16677744
38.

Optimal genotype determination in highly multiplexed SNP data.

Moorhead M, Hardenbol P, Siddiqui F, Falkowski M, Bruckner C, Ireland J, Jones HB, Jain M, Willis TD, Faham M.

Eur J Hum Genet. 2006 Feb;14(2):207-15. Erratum in: Eur J Hum Genet. 2006 Aug;14(8):976.

39.

Population structure, differential bias and genomic control in a large-scale, case-control association study.

Clayton DG, Walker NM, Smyth DJ, Pask R, Cooper JD, Maier LM, Smink LJ, Lam AC, Ovington NR, Stevens HE, Nutland S, Howson JM, Faham M, Moorhead M, Jones HB, Falkowski M, Hardenbol P, Willis TD, Todd JA.

Nat Genet. 2005 Nov;37(11):1243-6. Epub 2005 Oct 9.

PMID:
16228001
40.

Multiplexed variation scanning for 1,000 amplicons in hundreds of patients using mismatch repair detection (MRD) on tag arrays.

Faham M, Zheng J, Moorhead M, Fakhrai-Rad H, Namsaraev E, Wong K, Wang Z, Chow SG, Lee L, Suyenaga K, Reichert J, Boudreau A, Eberle J, Bruckner C, Jain M, Karlin-Neumann G, Jones HB, Willis TD, Buxbaum JD, Davis RW.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14717-22. Epub 2005 Oct 3.

41.
42.

Highly multiplexed molecular inversion probe genotyping: over 10,000 targeted SNPs genotyped in a single tube assay.

Hardenbol P, Yu F, Belmont J, Mackenzie J, Bruckner C, Brundage T, Boudreau A, Chow S, Eberle J, Erbilgin A, Falkowski M, Fitzgerald R, Ghose S, Iartchouk O, Jain M, Karlin-Neumann G, Lu X, Miao X, Moore B, Moorhead M, Namsaraev E, Pasternak S, Prakash E, Tran K, Wang Z, Jones HB, Davis RW, Willis TD, Gibbs RA.

Genome Res. 2005 Feb;15(2):269-75.

43.

Sex differences and organizational effects of androgen in spinal cord motor nuclei.

Grisham W, Jones HB, Park SH.

J Undergrad Neurosci Educ. 2003 Fall;2(1):A28-35. Epub 2003 Oct 15.

44.

Endothelin antagonist-induced coronary and systemic arteritis in the beagle dog.

Jones HB, Macpherson A, Betton GR, Davis AS, Siddall R, Greaves P.

Toxicol Pathol. 2003 May-Jun;31(3):263-72.

PMID:
12746113
45.

Laparoscopic inguinal hernia repair: lessons learned after 1224 consecutive cases.

Ramshaw B, Shuler FW, Jones HB, Duncan TD, White J, Wilson R, Lucas GW, Mason EM.

Surg Endosc. 2001 Jan;15(1):50-4.

PMID:
11178763
46.

Evidence that allelic variants of the spinocerebellar ataxia type 2 gene influence susceptibility to multiple sclerosis.

Chataway J, Sawcer S, Coraddu F, Feakes R, Broadley S, Jones HB, Clayton D, Gray J, Goodfellow PN, Compston A.

Neurogenetics. 1999 Apr;2(2):91-6.

PMID:
10369884
47.

Role of genetic resistance in invasive pneumococcal infection: identification and study of susceptibility and resistance in inbred mouse strains.

Gingles NA, Alexander JE, Kadioglu A, Andrew PW, Kerr A, Mitchell TJ, Hopes E, Denny P, Brown S, Jones HB, Little S, Booth GC, McPheat WL.

Infect Immun. 2001 Jan;69(1):426-34.

48.

Glycogenosomes in the aging rat brain: their occurrence in the visual pathways.

Cavanagh JB, Jones HB.

Acta Neuropathol. 2000 May;99(5):496-502.

PMID:
10805092
49.

Characterisation of Candida albicans infections of haematogenous and mucosal origin in mice lacking the interferon gamma receptor protein.

Londono LP, Jones HB, Vie AT, McPheat WL, Booth G, Gao XM, Dougan G.

FEMS Immunol Med Microbiol. 2000 Feb;27(2):117-25.

50.

No evidence for association of multiple sclerosis with the complement factors C6 and C7.

Chataway J, Sawcer S, Sherman D, Hobart M, Fernie B, Coraddu F, Feakes R, Broadley S, Gray J, Jones HB, Clayton D, Goodfellow PN, Compston A.

J Neuroimmunol. 1999 Sep 1;99(1):150-6.

PMID:
10496188

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