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Items: 1 to 50 of 401

1.

Forces and constraints controlling podosome assembly and disassembly.

Rafiq NBM, Grenci G, Lim CK, Kozlov MM, Jones GE, Viasnoff V, Bershadsky AD.

Philos Trans R Soc Lond B Biol Sci. 2019 Aug 19;374(1779):20180228. doi: 10.1098/rstb.2018.0228. Epub 2019 Jul 1.

PMID:
31431172
2.

Publisher Correction: A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions.

Rafiq NBM, Nishimura Y, Plotnikov SV, Thiagarajan V, Zhang Z, Shi S, Natarajan M, Viasnoff V, Kanchanawong P, Jones GE, Bershadsky AD.

Nat Mater. 2019 Jul;18(7):770. doi: 10.1038/s41563-019-0414-4.

PMID:
31147615
3.

A mechano-signalling network linking microtubules, myosin IIA filaments and integrin-based adhesions.

Rafiq NBM, Nishimura Y, Plotnikov SV, Thiagarajan V, Zhang Z, Shi S, Natarajan M, Viasnoff V, Kanchanawong P, Jones GE, Bershadsky AD.

Nat Mater. 2019 Jun;18(6):638-649. doi: 10.1038/s41563-019-0371-y. Epub 2019 May 21. Erratum in: Nat Mater. 2019 Jul;18(7):770.

PMID:
31114072
4.

Artifact-free high-density localization microscopy analysis.

Marsh RJ, Pfisterer K, Bennett P, Hirvonen LM, Gautel M, Jones GE, Cox S.

Nat Methods. 2018 Sep;15(9):689-692. doi: 10.1038/s41592-018-0072-5. Epub 2018 Jul 30.

PMID:
30061677
5.

The Rényi divergence enables accurate and precise cluster analysis for localization microscopy.

Staszowska AD, Fox-Roberts P, Hirvonen LM, Peddie CJ, Collinson LM, Jones GE, Cox S.

Bioinformatics. 2018 Dec 1;34(23):4102-4111. doi: 10.1093/bioinformatics/bty403.

6.

A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells.

Kovtun Y, Jones GE, Adams S, Harvey L, Audette CA, Wilhelm A, Bai C, Rui L, Laleau R, Liu F, Ab O, Setiady Y, Yoder NC, Goldmacher VS, Chari RVJ, Pinkas J, Chittenden T.

Blood Adv. 2018 Apr 24;2(8):848-858. doi: 10.1182/bloodadvances.2018017517.

7.

IMGN779, a Novel CD33-Targeting Antibody-Drug Conjugate with DNA-Alkylating Activity, Exhibits Potent Antitumor Activity in Models of AML.

Kovtun Y, Noordhuis P, Whiteman KR, Watkins K, Jones GE, Harvey L, Lai KC, Portwood S, Adams S, Sloss CM, Schuurhuis GJ, Ossenkoppele G, Wang ES, Pinkas J.

Mol Cancer Ther. 2018 Jun;17(6):1271-1279. doi: 10.1158/1535-7163.MCT-17-1077. Epub 2018 Mar 27.

8.

An approach to familial lymphoedema.

Jones GE, Mansour S.

Clin Med (Lond). 2017 Dec;17(6):552-557. doi: 10.7861/clinmedicine.17-6-552. Review.

9.

BCR-ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy.

Pereira WO, De Carvalho DD, Zenteno ME, Ribeiro BF, Jacysyn JF, Sardinha LR, Zanichelli MA, Hamerschlak N, Jones GE, Pagnano KB, Castro FA, Calle Y, Amarante-Mendes GP.

Cell Death Dis. 2017 Oct 12;8(10):e3114. doi: 10.1038/cddis.2017.458.

10.

Renal anomalies and lymphedema distichiasis syndrome. A rare association?

Jones GE, Richmond AK, Navti O, Mousa HA, Abbs S, Thompson E, Mansour S, Vasudevan PC.

Am J Med Genet A. 2017 Aug;173(8):2251-2256. doi: 10.1002/ajmg.a.38293. Epub 2017 May 23.

PMID:
28544699
11.

Analgesia for patients undergoing shockwave lithotripsy for urinary stones - a systematic review and meta-analysis.

Aboumarzouk OM, Hasan R, Tasleem A, Mariappan M, Hutton R, Fitzpatrick J, Beatty L, Jones GE, Amer T.

Int Braz J Urol. 2017 May-Jun;43(3):394-406. doi: 10.1590/S1677-5538.IBJU.2016.0078. Review.

12.

Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO.

Rafiq NB, Lieu ZZ, Jiang T, Yu CH, Matsudaira P, Jones GE, Bershadsky AD.

J Cell Biol. 2017 Jan 2;216(1):181-197. doi: 10.1083/jcb.201605104. Epub 2016 Dec 22.

13.

Investigation of podosome ring protein arrangement using localization microscopy images.

Staszowska AD, Fox-Roberts P, Foxall E, Jones GE, Cox S.

Methods. 2017 Feb 15;115:9-16. doi: 10.1016/j.ymeth.2016.11.005. Epub 2016 Nov 10.

14.

Pyopericardium secondary to achalasia-associated squamous cell carcinoma of the oesophagus.

Mason JD, Dixon F, Grimes H, Jones GE.

Ann R Coll Surg Engl. 2017 Jan;99(1):e22-e23. doi: 10.1308/rcsann.2016.0279. Epub 2016 Aug 23.

15.

Significance of kinase activity in the dynamic invadosome.

Foxall E, Pipili A, Jones GE, Wells CM.

Eur J Cell Biol. 2016 Nov;95(11):483-492. doi: 10.1016/j.ejcb.2016.07.002. Epub 2016 Jul 19. Review.

PMID:
27465307
16.

A New Triglycyl Peptide Linker for Antibody-Drug Conjugates (ADCs) with Improved Targeted Killing of Cancer Cells.

Singh R, Setiady YY, Ponte J, Kovtun YV, Lai KC, Hong EE, Fishkin N, Dong L, Jones GE, Coccia JA, Lanieri L, Veale K, Costoplus JA, Skaletskaya A, Gabriel R, Salomon P, Wu R, Qiu Q, Erickson HK, Lambert JM, Chari RV, Widdison WC.

Mol Cancer Ther. 2016 Jun;15(6):1311-20. doi: 10.1158/1535-7163.MCT-16-0021. Epub 2016 Mar 29.

17.

LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP.

Lagoutte E, Villeneuve C, Lafanechère L, Wells CM, Jones GE, Chavrier P, Rossé C.

Sci Rep. 2016 Apr 27;6:24925. doi: 10.1038/srep24925.

18.

Tailored Lighting Intervention for Persons with Dementia and Caregivers Living at Home.

Figueiro MG, Hunter CM, Higgins P, Hornick T, Jones GE, Plitnick B, Brons J, Rea MS.

Sleep Health. 2015 Dec 1;1(4):322-330.

19.

Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases.

Miles TJ, Hennessy AJ, Bax B, Brooks G, Brown BS, Brown P, Cailleau N, Chen D, Dabbs S, Davies DT, Esken JM, Giordano I, Hoover JL, Jones GE, Kusalakumari Sukmar SK, Markwell RE, Minthorn EA, Rittenhouse S, Gwynn MN, Pearson ND.

Bioorg Med Chem Lett. 2016 May 15;26(10):2464-2469. doi: 10.1016/j.bmcl.2016.03.106. Epub 2016 Mar 31.

PMID:
27055939
20.

Restaging oesophageal cancer after neoadjuvant therapy with (18)F-FDG PET-CT: identifying interval metastases and predicting incurable disease at surgery.

Findlay JM, Gillies RS, Franklin JM, Teoh EJ, Jones GE, di Carlo S, Gleeson FV, Maynard ND, Bradley KM, Middleton MR.

Eur Radiol. 2016 Oct;26(10):3519-33. doi: 10.1007/s00330-016-4227-4. Epub 2016 Feb 16.

PMID:
26883329
21.

14q22.3 Microdeletion encompassing OTX2 in a five-generation family with microphthalmia, pituitary abnormalities, and intellectual disability.

Jones GE, Robertson L, Warman P, Craft EV, Cresswell L, Vasudevan PC.

Ophthalmic Genet. 2016 Sep;37(3):352-3. doi: 10.3109/13816810.2015.1059463. Epub 2016 Feb 9. No abstract available.

PMID:
26860946
22.

Developing and assessing the utility of a You-Tube based clinical genetics video channel for families affected by inherited tumours.

Jones GE, Singletary JH, Cashmore A, Jain V, Abhulimhen J, Chauhan J, Musson HV, Barwell JG.

Fam Cancer. 2016 Apr;15(2):351-5. doi: 10.1007/s10689-016-9866-8.

PMID:
26753801
23.

Microform holoprosencephaly with bilateral congenital elbow dislocation; increasing the phenotypic spectrum of Steinfeld syndrome.

Jones GE, Robertson L, Maniyar A, Shammas C, Phelan MM, Vasudevan PC, Tanteles GA.

Am J Med Genet A. 2016 Mar;170(3):754-9. doi: 10.1002/ajmg.a.37511. Epub 2016 Jan 5.

PMID:
26728615
24.

Marine Diterpenoids as Potential Anti-Inflammatory Agents.

González Y, Torres-Mendoza D, Jones GE, Fernandez PL.

Mediators Inflamm. 2015;2015:263543. doi: 10.1155/2015/263543. Epub 2015 Oct 11. Review.

25.

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force.

Yu CH, Rafiq NB, Cao F, Zhou Y, Krishnasamy A, Biswas KH, Ravasio A, Chen Z, Wang YH, Kawauchi K, Jones GE, Sheetz MP.

Nat Commun. 2015 Oct 28;6:8672. doi: 10.1038/ncomms9672.

26.
27.

Usefulness of early post-operative liver function test monitoring after laparoscopic common bile duct exploration.

Wewelwala C, Cashin P, Berry R, Blamey S, Jones GE, Croagh DG.

ANZ J Surg. 2017 Nov;87(11):925-929. doi: 10.1111/ans.13217. Epub 2015 Jul 14.

PMID:
26179768
28.

At-sea trial of 24-h-based submarine watchstanding schedules with high and low correlated color temperature light sources.

Young CR, Jones GE, Figueiro MG, Soutière SE, Keller MW, Richardson AM, Lehmann BJ, Rea MS.

J Biol Rhythms. 2015 Apr;30(2):144-54. doi: 10.1177/0748730415575432.

PMID:
25838419
29.

Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability.

Martín-Villar E, Borda-d'Agua B, Carrasco-Ramirez P, Renart J, Parsons M, Quintanilla M, Jones GE.

Oncogene. 2015 Aug 20;34(34):4531-44. doi: 10.1038/onc.2014.388. Epub 2014 Dec 8.

30.

Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages.

Vijayakumar V, Monypenny J, Chen XJ, Machesky LM, Lilla S, Thrasher AJ, Antón IM, Calle Y, Jones GE.

J Cell Sci. 2015 Jan 15;128(2):251-65. doi: 10.1242/jcs.154880. Epub 2014 Nov 20.

31.

Tailored lighting intervention improves measures of sleep, depression, and agitation in persons with Alzheimer's disease and related dementia living in long-term care facilities.

Figueiro MG, Plitnick BA, Lok A, Jones GE, Higgins P, Hornick TR, Rea MS.

Clin Interv Aging. 2014 Sep 12;9:1527-37. doi: 10.2147/CIA.S68557. eCollection 2014.

32.

WIP is necessary for matrix invasion by breast cancer cells.

García E, Machesky LM, Jones GE, Antón IM.

Eur J Cell Biol. 2014 Oct;93(10-12):413-23. doi: 10.1016/j.ejcb.2014.07.008. Epub 2014 Aug 7.

PMID:
25169059
33.

Vinculin binding angle in podosomes revealed by high resolution microscopy.

Walde M, Monypenny J, Heintzmann R, Jones GE, Cox S.

PLoS One. 2014 Feb 11;9(2):e88251. doi: 10.1371/journal.pone.0088251. eCollection 2014.

34.

Integrin linked kinase (ILK) regulates podosome maturation and stability in dendritic cells.

Griera M, Martin-Villar E, Banon-Rodríguez I, Blundell MP, Jones GE, Anton IM, Thrasher AJ, Rodriguez-Puyol M, Calle Y.

Int J Biochem Cell Biol. 2014 May;50:47-54. doi: 10.1016/j.biocel.2014.01.021. Epub 2014 Feb 6.

35.

Daily activity and light exposure levels for five species of lemurs at the Duke Lemur Center.

Rea MS, Figueiro MG, Jones GE, Glander KE.

Am J Phys Anthropol. 2014 Jan;153(1):68-77. doi: 10.1002/ajpa.22409. Epub 2013 Nov 6.

PMID:
24318943
36.

Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces.

Yu CH, Rafiq NB, Krishnasamy A, Hartman KL, Jones GE, Bershadsky AD, Sheetz MP.

Cell Rep. 2013 Dec 12;5(5):1456-68. doi: 10.1016/j.celrep.2013.10.040. Epub 2013 Nov 27.

37.

Glomus body tumor of the breast: a rare cause of isolated breast pain.

Crandall GA, Jones GE.

Plast Reconstr Surg. 2013 Dec;132(6):1087e-8e. doi: 10.1097/PRS.0b013e3182a9803f. No abstract available.

PMID:
24281631
38.

Microcephaly with or without chorioretinopathy, lymphoedema, or mental retardation (MCLMR): review of phenotype associated with KIF11 mutations.

Jones GE, Ostergaard P, Moore AT, Connell FC, Williams D, Quarrell O, Brady AF, Spier I, Hazan F, Moldovan O, Wieczorek D, Mikat B, Petit F, Coubes C, Saul RA, Brice G, Gordon K, Jeffery S, Mortimer PS, Vasudevan PC, Mansour S.

Eur J Hum Genet. 2014 Jul;22(7):881-7. doi: 10.1038/ejhg.2013.263. Epub 2013 Nov 27.

39.

A novel mutation in NIPBL in a case of Cornelia de Lange syndrome confirmed with genetic testing following intrauterine fetal death. [Corrected].

Jones GE, Tanteles GA, Vasudevan PC, Porter H, Robertson L.

J Clin Pathol. 2014 Mar;67(3):283-4. doi: 10.1136/jclinpath-2013-201856. Epub 2013 Nov 4. No abstract available. Erratum in: J Clin Pathol. 2014 Nov;67(11):1018.

PMID:
24189319
40.

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases.

Miles TJ, Hennessy AJ, Bax B, Brooks G, Brown BS, Brown P, Cailleau N, Chen D, Dabbs S, Davies DT, Esken JM, Giordano I, Hoover JL, Huang J, Jones GE, Sukmar SK, Spitzfaden C, Markwell RE, Minthorn EA, Rittenhouse S, Gwynn MN, Pearson ND.

Bioorg Med Chem Lett. 2013 Oct 1;23(19):5437-41. doi: 10.1016/j.bmcl.2013.07.013. Epub 2013 Jul 17.

PMID:
23968823
41.

WIP regulates persistence of cell migration and ruffle formation in both mesenchymal and amoeboid modes of motility.

Banon-Rodriguez I, Saez de Guinoa J, Bernardini A, Ragazzini C, Fernandez E, Carrasco YR, Jones GE, Wandosell F, Anton IM.

PLoS One. 2013 Aug 7;8(8):e70364. doi: 10.1371/journal.pone.0070364. eCollection 2013.

42.

Imaging cells at the nanoscale.

Cox S, Jones GE.

Int J Biochem Cell Biol. 2013 Aug;45(8):1669-78. doi: 10.1016/j.biocel.2013.05.010. Epub 2013 May 18. Review.

PMID:
23688552
43.

Imaging haematopoietic cells recruitment to an acute wound in vivo identifies a role for c-Met signalling.

Falenta K, Rodaway A, Jones GE, Wells CM.

J Microsc. 2013 Jun;250(3):200-9. doi: 10.1111/jmi.12035. Epub 2013 Apr 12.

44.

Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoform.

Staben ST, Ndubaku C, Blaquiere N, Belvin M, Bull RJ, Dudley D, Edgar K, Gray D, Heald R, Heffron TP, Jones GE, Jones M, Kolesnikov A, Lee L, Lesnick J, Lewis C, Murray J, McLean NJ, Nonomiya J, Olivero AG, Ord R, Pang J, Price S, Prior WW, Rouge L, Salphati L, Sampath D, Wallin J, Wang L, Wei B, Weismann C, Wu P.

Bioorg Med Chem Lett. 2013 May 1;23(9):2606-13. doi: 10.1016/j.bmcl.2013.02.102. Epub 2013 Mar 7.

PMID:
23540645
45.

Nox2 is required for macrophage chemotaxis towards CSF-1.

Chaubey S, Jones GE, Shah AM, Cave AC, Wells CM.

PLoS One. 2013;8(2):e54869. doi: 10.1371/journal.pone.0054869. Epub 2013 Feb 1.

46.

ImageJ plug-in for Bayesian analysis of blinking and bleaching.

Rosten E, Jones GE, Cox S.

Nat Methods. 2013 Feb;10(2):97-8. doi: 10.1038/nmeth.2342. No abstract available.

PMID:
23361088
47.

Quantitative DTI assessment in human lumbar stabilization muscles at 3 T.

Jones GE, Kumbhare DA, Harish S, Noseworthy MD.

J Comput Assist Tomogr. 2013 Jan-Feb;37(1):98-104. doi: 10.1097/RCT.0b013e3182772d66.

PMID:
23321840
48.

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane.

Schachtner H, Calaminus SD, Sinclair A, Monypenny J, Blundell MP, Leon C, Holyoake TL, Thrasher AJ, Michie AM, Vukovic M, Gachet C, Jones GE, Thomas SG, Watson SP, Machesky LM.

Blood. 2013 Mar 28;121(13):2542-52. doi: 10.1182/blood-2012-07-443457. Epub 2013 Jan 10.

49.

Intraoperative laser angiography using the SPY system: review of the literature and recommendations for use.

Gurtner GC, Jones GE, Neligan PC, Newman MI, Phillips BT, Sacks JM, Zenn MR.

Ann Surg Innov Res. 2013 Jan 7;7(1):1. doi: 10.1186/1750-1164-7-1.

50.

WIP: WASP-interacting proteins at invadopodia and podosomes.

García E, Jones GE, Machesky LM, Antón IM.

Eur J Cell Biol. 2012 Nov-Dec;91(11-12):869-77. doi: 10.1016/j.ejcb.2012.06.002. Epub 2012 Jul 21. Review.

PMID:
22823953

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