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Absence of synemin in mice causes structural and functional abnormalities in heart.

GarcĂ­a-Pelagio KP, Chen L, Joca HC, Ward C, Jonathan Lederer W, Bloch RJ.

J Mol Cell Cardiol. 2018 Jan;114:354-363. doi: 10.1016/j.yjmcc.2017.12.005. Epub 2017 Dec 14.


Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.

Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.

Sci Adv. 2017 Jun 7;3(6):e1603081. doi: 10.1126/sciadv.1603081. eCollection 2017 Jun.


Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy.

Wessely R, Klingel K, Santana LF, Dalton N, Hongo M, Jonathan Lederer W, Kandolf R, Knowlton KU.

J Clin Invest. 1998 Oct 1;102(7):1444-53.

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