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Items: 1 to 50 of 71

1.

Cardiac metabolic effects of KNa1.2 channel deletion and evidence for its mitochondrial localization.

Smith CO, Wang YT, Nadtochiy SM, Miller JH, Jonas EA, Dirksen RT, Nehrke K, Brookes PS.

FASEB J. 2018 Jun 4:fj201800139R. doi: 10.1096/fj.201800139R. [Epub ahead of print]

PMID:
29863912
2.

BDNF signaling: Harnessing stress to battle mood disorder.

Licznerski P, Jonas EA.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3742-3744. doi: 10.1073/pnas.1803645115. Epub 2018 Mar 28. No abstract available.

3.

ΔN-Bcl-xL, a therapeutic target for neuroprotection.

Park HA, Jonas EA.

Neural Regen Res. 2017 Nov;12(11):1791-1794. doi: 10.4103/1673-5374.219033. Review.

4.

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

Connolly NMC, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JHM.

Cell Death Differ. 2018 Mar;25(3):542-572. doi: 10.1038/s41418-017-0020-4. Epub 2017 Dec 11. Review.

PMID:
29229998
5.

Phylogenetic Profiling of Mitochondrial Proteins and Integration Analysis of Bacterial Transcription Units Suggest Evolution of F1Fo ATP Synthase from Multiple Modules.

Niu Y, Moghimyfiroozabad S, Safaie S, Yang Y, Jonas EA, Alavian KN.

J Mol Evol. 2017 Dec;85(5-6):219-233. doi: 10.1007/s00239-017-9819-3. Epub 2017 Nov 24.

6.

Inhibition of Bcl-xL prevents pro-death actions of ΔN-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity.

Park HA, Licznerski P, Mnatsakanyan N, Niu Y, Sacchetti S, Wu J, Polster BM, Alavian KN, Jonas EA.

Cell Death Differ. 2017 Nov;24(11):1963-1974. doi: 10.1038/cdd.2017.123. Epub 2017 Aug 4.

7.

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis.

Zille M, Karuppagounder SS, Chen Y, Gough PJ, Bertin J, Finger J, Milner TA, Jonas EA, Ratan RR.

Stroke. 2017 Apr;48(4):1033-1043. doi: 10.1161/STROKEAHA.116.015609. Epub 2017 Mar 1.

8.

Erratum to: The Mitochondrial Permeability Transition Pore and ATP Synthase.

Beutner G, Alavian KN, Jonas EA, Porter GA Jr.

Handb Exp Pharmacol. 2017;240:489. doi: 10.1007/164_2016_87. No abstract available.

PMID:
27913888
9.

The Mitochondrial Permeability Transition Pore and ATP Synthase.

Beutner G, Alavian KN, Jonas EA, Porter GA Jr.

Handb Exp Pharmacol. 2017;240:21-46. doi: 10.1007/164_2016_5. Erratum in: Handb Exp Pharmacol. 2017;240:489.

PMID:
27590224
10.

Physiological roles of the mitochondrial permeability transition pore.

Mnatsakanyan N, Beutner G, Porter GA, Alavian KN, Jonas EA.

J Bioenerg Biomembr. 2017 Feb;49(1):13-25. doi: 10.1007/s10863-016-9652-1. Epub 2016 Feb 11. Review.

11.

Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress.

Licznerski P, Duric V, Banasr M, Alavian KN, Ota KT, Kang HJ, Jonas EA, Ursano R, Krystal JH, Duman RS; Traumatic Stress Brain Study Group.

PLoS Biol. 2015 Oct 27;13(10):e1002282. doi: 10.1371/journal.pbio.1002282. eCollection 2015 Oct.

12.

Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F(1)F(O) ATP synthase.

Jonas EA, Porter GA Jr, Beutner G, Mnatsakanyan N, Alavian KN.

Pharmacol Res. 2015 Sep;99:382-92. doi: 10.1016/j.phrs.2015.04.013. Epub 2015 May 5. Review.

13.
14.

Mitochondrial membrane protein Bcl-xL, a regulator of adult neuronal growth and synaptic plasticity: multiple functions beyond apoptosis.

Park HA, Jonas EA.

Neural Regen Res. 2014 Oct 1;9(19):1706-7. doi: 10.4103/1673-5374.143413. No abstract available.

15.

The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole.

Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Li H, Signore AP, Smith PJ, Gribkoff VK, Jonas EA.

Mol Pharmacol. 2015 Jan;87(1):1-8. doi: 10.1124/mol.114.095661. Epub 2014 Oct 20.

16.

Bcl-xL in neuroprotection and plasticity.

Jonas EA, Porter GA, Alavian KN.

Front Physiol. 2014 Sep 17;5:355. doi: 10.3389/fphys.2014.00355. eCollection 2014. Review.

17.

An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore.

Alavian KN, Beutner G, Lazrove E, Sacchetti S, Park HA, Licznerski P, Li H, Nabili P, Hockensmith K, Graham M, Porter GA Jr, Jonas EA.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10580-5. doi: 10.1073/pnas.1401591111. Epub 2014 Jun 16.

18.

Impaired import: how huntingtin harms.

Jonas EA.

Nat Neurosci. 2014 Jun;17(6):747-9. doi: 10.1038/nn.3726. No abstract available.

19.

Bcl-xL is necessary for neurite outgrowth in hippocampal neurons.

Park HA, Licznerski P, Alavian KN, Shanabrough M, Jonas EA.

Antioxid Redox Signal. 2015 Jan 10;22(2):93-108. doi: 10.1089/ars.2013.5570.

20.

Contributions of Bcl-xL to acute and long term changes in bioenergetics during neuronal plasticity.

Jonas EA.

Biochim Biophys Acta. 2014 Aug;1842(8):1168-78. doi: 10.1016/j.bbadis.2013.11.007. Epub 2013 Nov 12. Review.

21.

A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis.

Li H, Alavian KN, Lazrove E, Mehta N, Jones A, Zhang P, Licznerski P, Graham M, Uo T, Guo J, Rahner C, Duman RS, Morrison RS, Jonas EA.

Nat Cell Biol. 2013 Jul;15(7):773-85. doi: 10.1038/ncb2791. Epub 2013 Jun 23.

22.

F1FO ATPase vesicle preparation and technique for performing patch clamp recordings of submitochondrial vesicle membranes.

Sacchetti S, Alavian KN, Lazrove E, Jonas EA.

J Vis Exp. 2013 May 4;(75):e4394. doi: 10.3791/4394.

23.

PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage.

Arena G, Gelmetti V, Torosantucci L, Vignone D, Lamorte G, De Rosa P, Cilia E, Jonas EA, Valente EM.

Cell Death Differ. 2013 Jul;20(7):920-30. doi: 10.1038/cdd.2013.19. Epub 2013 Mar 22.

24.

Mouse Transient Global Ischemia Two-Vessel Occlusion Model.

Pontarelli F, Ofengeim D, Zukin RS, Jonas EA.

Bio Protoc. 2012 Sep 20;2(18). pii: e262.

25.

Multipolar functions of BCL-2 proteins link energetics to apoptosis.

Hardwick JM, Chen YB, Jonas EA.

Trends Cell Biol. 2012 Jun;22(6):318-28. doi: 10.1016/j.tcb.2012.03.005. Epub 2012 May 5. Review.

26.

NAD kinase regulates the size of the NADPH pool and insulin secretion in pancreatic β-cells.

Gray JP, Alavian KN, Jonas EA, Heart EA.

Am J Physiol Endocrinol Metab. 2012 Jul 15;303(2):E191-9. doi: 10.1152/ajpendo.00465.2011. Epub 2012 May 1.

27.

N-terminally cleaved Bcl-xL mediates ischemia-induced neuronal death.

Ofengeim D, Chen YB, Miyawaki T, Li H, Sacchetti S, Flannery RJ, Alavian KN, Pontarelli F, Roelofs BA, Hickman JA, Hardwick JM, Zukin RS, Jonas EA.

Nat Neurosci. 2012 Feb 26;15(4):574-80. doi: 10.1038/nn.3054.

28.

Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency.

Alavian KN, Dworetzky SI, Bonanni L, Zhang P, Sacchetti S, Mariggio MA, Onofrj M, Thomas A, Li H, Mangold JE, Signore AP, Demarco U, Demady DR, Nabili P, Lazrove E, Smith PJ, Gribkoff VK, Jonas EA.

Brain Res. 2012 Mar 29;1446:1-11. doi: 10.1016/j.brainres.2012.01.046. Epub 2012 Jan 28.

29.

Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential.

Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, Pedersen PL, Kaczmarek LK, Jonas EA, Hardwick JM.

J Cell Biol. 2011 Oct 17;195(2):263-76. doi: 10.1083/jcb.201108059. Epub 2011 Oct 10.

30.

Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.

Alavian KN, Li H, Collis L, Bonanni L, Zeng L, Sacchetti S, Lazrove E, Nabili P, Flaherty B, Graham M, Chen Y, Messerli SM, Mariggio MA, Rahner C, McNay E, Shore GC, Smith PJ, Hardwick JM, Jonas EA.

Nat Cell Biol. 2011 Sep 18;13(10):1224-33. doi: 10.1038/ncb2330. Erratum in: Nat Cell Biol. 2011 Nov;13(11):1383.

31.

Molecular participants in mitochondrial cell death channel formation during neuronal ischemia.

Jonas EA.

Exp Neurol. 2009 Aug;218(2):203-12. doi: 10.1016/j.expneurol.2009.03.025. Epub 2009 Mar 31. Review.

32.

Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons.

Berman SB, Chen YB, Qi B, McCaffery JM, Rucker EB 3rd, Goebbels S, Nave KA, Arnold BA, Jonas EA, Pineda FJ, Hardwick JM.

J Cell Biol. 2009 Mar 9;184(5):707-19. doi: 10.1083/jcb.200809060. Epub 2009 Mar 2.

33.

Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons.

Miyawaki T, Mashiko T, Ofengeim D, Flannery RJ, Noh KM, Fujisawa S, Bonanni L, Bennett MV, Zukin RS, Jonas EA.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4892-7. doi: 10.1073/pnas.0800628105. Epub 2008 Mar 17. Erratum in: Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16855-7.

34.

PKC-induced intracellular trafficking of Ca(V)2 precedes its rapid recruitment to the plasma membrane.

Zhang Y, Helm JS, Senatore A, Spafford JD, Kaczmarek LK, Jonas EA.

J Neurosci. 2008 Mar 5;28(10):2601-12. doi: 10.1523/JNEUROSCI.4314-07.

35.

Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons.

Li H, Chen Y, Jones AF, Sanger RH, Collis LP, Flannery R, McNay EC, Yu T, Schwarzenbacher R, Bossy B, Bossy-Wetzel E, Bennett MV, Pypaert M, Hickman JA, Smith PJ, Hardwick JM, Jonas EA.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2169-74. doi: 10.1073/pnas.0711647105. Epub 2008 Feb 4.

36.

Bcl-xL inhibitor ABT-737 reveals a dual role for Bcl-xL in synaptic transmission.

Hickman JA, Hardwick JM, Kaczmarek LK, Jonas EA.

J Neurophysiol. 2008 Mar;99(3):1515-22. Epub 2007 Dec 26.

37.

Expression of the voltage-gated sodium channel NaV1.5 in the macrophage late endosome regulates endosomal acidification.

Carrithers MD, Dib-Hajj S, Carrithers LM, Tokmoulina G, Pypaert M, Jonas EA, Waxman SG.

J Immunol. 2007 Jun 15;178(12):7822-32.

38.

Hypoxia increases BK channel activity in the inner mitochondrial membrane.

Gu XQ, Siemen D, Parvez S, Cheng Y, Xue J, Zhou D, Sun X, Jonas EA, Haddad GG.

Biochem Biophys Res Commun. 2007 Jun 22;358(1):311-6. Epub 2007 Apr 25.

PMID:
17481584
39.

Mitochondrial factors with dual roles in death and survival.

Cheng WC, Berman SB, Ivanovska I, Jonas EA, Lee SJ, Chen Y, Kaczmarek LK, Pineda F, Hardwick JM.

Oncogene. 2006 Aug 7;25(34):4697-705. Review.

PMID:
16892083
40.

Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.

Bonanni L, Chachar M, Jover-Mengual T, Li H, Jones A, Yokota H, Ofengeim D, Flannery RJ, Miyawaki T, Cho CH, Polster BM, Pypaert M, Hardwick JM, Sensi SL, Zukin RS, Jonas EA.

J Neurosci. 2006 Jun 21;26(25):6851-62.

41.

The role of the mitochondrial apoptosis induced channel MAC in cytochrome c release.

Martinez-Caballero S, Dejean LM, Jonas EA, Kinnally KW.

J Bioenerg Biomembr. 2005 Jun;37(3):155-64. Review.

PMID:
16167172
42.

Actions of BAX on mitochondrial channel activity and on synaptic transmission.

Jonas EA, Hardwick JM, Kaczmarek LK.

Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1092-100.

PMID:
16115013
43.

Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel.

Dejean LM, Martinez-Caballero S, Guo L, Hughes C, Teijido O, Ducret T, Ichas F, Korsmeyer SJ, Antonsson B, Jonas EA, Kinnally KW.

Mol Biol Cell. 2005 May;16(5):2424-32. Epub 2005 Mar 16.

44.

Exposure to hypoxia rapidly induces mitochondrial channel activity within a living synapse.

Jonas EA, Hickman JA, Hardwick JM, Kaczmarek LK.

J Biol Chem. 2005 Feb 11;280(6):4491-7. Epub 2004 Nov 23.

45.

Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals.

Jonas EA, Hickman JA, Chachar M, Polster BM, Brandt TA, Fannjiang Y, Ivanovska I, Basañez G, Kinnally KW, Zimmerberg J, Hardwick JM, Kaczmarek LK.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13590-5. Epub 2004 Sep 1.

46.

Modulation of synaptic transmission by the BCL-2 family protein BCL-xL.

Jonas EA, Hoit D, Hickman JA, Brandt TA, Polster BM, Fannjiang Y, McCarthy E, Montanez MK, Hardwick JM, Kaczmarek LK.

J Neurosci. 2003 Sep 10;23(23):8423-31.

47.

Modulation of mitochondrial function by endogenous Zn2+ pools.

Sensi SL, Ton-That D, Sullivan PG, Jonas EA, Gee KR, Kaczmarek LK, Weiss JH.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):6157-62. Epub 2003 Apr 30.

48.

BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development.

Fannjiang Y, Kim CH, Huganir RL, Zou S, Lindsten T, Thompson CB, Mito T, Traystman RJ, Larsen T, Griffin DE, Mandir AS, Dawson TM, Dike S, Sappington AL, Kerr DA, Jonas EA, Kaczmarek LK, Hardwick JM.

Dev Cell. 2003 Apr;4(4):575-85.

49.

Prolonged activation of mitochondrial conductances during synaptic transmission.

Jonas EA, Buchanan J, Kaczmarek LK.

Science. 1999 Nov 12;286(5443):1347-50.

50.

Acute myocardial infarction with normal coronary artery: a case report and review of literature.

Manzar KJ, Padder FA, Conrad AR, Freeman I, Jonas EA.

Am J Med Sci. 1997 Nov;314(5):342-5. Review.

PMID:
9365338

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