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Items: 21


A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue.

Rana BMJ, Jou E, Barlow JL, Rodriguez-Rodriguez N, Walker JA, Knox C, Jolin HE, Hardman CS, Sivasubramaniam M, Szeto A, Cohen ES, Scott IC, Sleeman MA, Chidomere CI, Cruz Migoni S, Caamano J, Jorgensen HF, Carobbio S, Vidal-Puig A, McKenzie ANJ.

J Exp Med. 2019 Jun 27. pii: jem.20190689. doi: 10.1084/jem.20190689. [Epub ahead of print]


Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone Marrow.

Walker JA, Clark PA, Crisp A, Barlow JL, Szeto A, Ferreira ACF, Rana BMJ, Jolin HE, Rodriguez-Rodriguez N, Sivasubramaniam M, Pannell R, Cruickshank J, Daly M, Haim-Vilmovsky L, Teichmann SA, McKenzie ANJ.

Immunity. 2019 Jul 16;51(1):104-118.e7. doi: 10.1016/j.immuni.2019.05.002. Epub 2019 May 22.


BET Bromodomain Inhibitor iBET151 Impedes Human ILC2 Activation and Prevents Experimental Allergic Lung Inflammation.

Kerscher B, Barlow JL, Rana BM, Jolin HE, Gogoi M, Bartholomew MA, Jhamb D, Pandey A, Tough DF, van Oosterhout AJM, McKenzie ANJ.

Front Immunol. 2019 Apr 9;10:678. doi: 10.3389/fimmu.2019.00678. eCollection 2019.


Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.

Halim TYF, Rana BMJ, Walker JA, Kerscher B, Knolle MD, Jolin HE, Serrao EM, Haim-Vilmovsky L, Teichmann SA, Rodewald HR, Botto M, Vyse TJ, Fallon PG, Li Z, Withers DR, McKenzie ANJ.

Immunity. 2018 Jun 19;48(6):1195-1207.e6. doi: 10.1016/j.immuni.2018.05.003. Epub 2018 Jun 12.


GRAF1a is a brain-specific protein that promotes lipid droplet clustering and growth, and is enriched at lipid droplet junctions.

Lucken-Ardjomande Häsler S, Vallis Y, Jolin HE, McKenzie AN, McMahon HT.

J Cell Sci. 2014 Nov 1;127(Pt 21):4602-19. doi: 10.1242/jcs.147694. Epub 2014 Sep 4.


Transcription factor RORα is critical for nuocyte development.

Wong SH, Walker JA, Jolin HE, Drynan LF, Hams E, Camelo A, Barlow JL, Neill DR, Panova V, Koch U, Radtke F, Hardman CS, Hwang YY, Fallon PG, McKenzie AN.

Nat Immunol. 2012 Jan 22;13(3):229-36. doi: 10.1038/ni.2208.


Tim1 and Tim3 are not essential for experimental allergic asthma.

Barlow JL, Wong SH, Ballantyne SJ, Jolin HE, McKenzie AN.

Clin Exp Allergy. 2011 Jul;41(7):1012-21. doi: 10.1111/j.1365-2222.2011.03728.x. Epub 2011 Apr 7.


Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity.

Neill DR, Wong SH, Bellosi A, Flynn RJ, Daly M, Langford TK, Bucks C, Kane CM, Fallon PG, Pannell R, Jolin HE, McKenzie AN.

Nature. 2010 Apr 29;464(7293):1367-70. doi: 10.1038/nature08900. Epub 2010 Mar 3.


A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.

Barlow JL, Drynan LF, Hewett DR, Holmes LR, Lorenzo-Abalde S, Lane AL, Jolin HE, Pannell R, Middleton AJ, Wong SH, Warren AJ, Wainscoat JS, Boultwood J, McKenzie AN.

Nat Med. 2010 Jan;16(1):59-66. doi: 10.1038/nm.2063. Epub 2009 Nov 22.


Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma.

Ballantyne SJ, Barlow JL, Jolin HE, Nath P, Williams AS, Chung KF, Sturton G, Wong SH, McKenzie AN.

J Allergy Clin Immunol. 2007 Dec;120(6):1324-31. Epub 2007 Sep 24.


Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion.

Fallon PG, Ballantyne SJ, Mangan NE, Barlow JL, Dasvarma A, Hewett DR, McIlgorm A, Jolin HE, McKenzie AN.

J Exp Med. 2006 Apr 17;203(4):1105-16. Epub 2006 Apr 10.


Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome.

Hewett DR, Simons AL, Mangan NE, Jolin HE, Green SM, Fallon PG, McKenzie AN.

Hum Mol Genet. 2005 Jan 15;14(2):335-46. Epub 2004 Dec 8.


SIGN-R1 contributes to protection against lethal pneumococcal infection in mice.

Lanoue A, Clatworthy MR, Smith P, Green S, Townsend MJ, Jolin HE, Smith KG, Fallon PG, McKenzie AN.

J Exp Med. 2004 Dec 6;200(11):1383-93.


Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL-9 and are differentially dependent on Th2 cytokines.

Lauder AJ, Jolin HE, Smith P, van den Berg JG, Jones A, Wisden W, Smith KG, Dasvarma A, Fallon PG, McKenzie AN.

J Immunol. 2004 Jul 1;173(1):113-22.


Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.

Cope DW, Wulff P, Oberto A, Aller MI, Capogna M, Ferraguti F, Halbsguth C, Hoeger H, Jolin HE, Jones A, McKenzie AN, Ogris W, Poeltl A, Sinkkonen ST, Vekovischeva OY, Korpi ER, Sieghart W, Sigel E, Somogyi P, Wisden W.

Neuropharmacology. 2004 Jul;47(1):17-34.


Cerebellar granule cell Cre recombinase expression.

Aller MI, Jones A, Merlo D, Paterlini M, Meyer AH, Amtmann U, Brickley S, Jolin HE, McKenzie AN, Monyer H, Farrant M, Wisden W.

Genesis. 2003 Jun;36(2):97-103.


IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13.

Fallon PG, Jolin HE, Smith P, Emson CL, Townsend MJ, Fallon R, Smith P, McKenzie AN.

Immunity. 2002 Jul;17(1):7-17.


T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses.

Townsend MJ, Fallon PG, Matthews DJ, Jolin HE, McKenzie AN.

J Exp Med. 2000 Mar 20;191(6):1069-76.


IL-13 is a susceptibility factor for Leishmania major infection.

Matthews DJ, Emson CL, McKenzie GJ, Jolin HE, Blackwell JM, McKenzie AN.

J Immunol. 2000 Feb 1;164(3):1458-62.


Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor.

Kamalati T, Jolin HE, Mitchell PJ, Barker KT, Jackson LE, Dean CJ, Page MJ, Gusterson BA, Crompton MR.

J Biol Chem. 1996 Nov 29;271(48):30956-63.

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