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Items: 10

1.

AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis.

Chow BSM, Kocan M, Shen M, Wang Y, Han L, Chew JY, Wang C, Bosnyak S, Mirabito-Colafella KM, Barsha G, Wigg B, Johnstone EKM, Hossain MA, Pfleger KDG, Denton KM, Widdop RE, Summers RJ, Bathgate RAD, Hewitson TD, Samuel CS.

J Am Soc Nephrol. 2019 Sep 11. pii: ASN.2019060597. doi: 10.1681/ASN.2019060597. [Epub ahead of print]

PMID:
31511361
2.

NanoBRET: The Bright Future of Proximity-Based Assays.

Dale NC, Johnstone EKM, White CW, Pfleger KDG.

Front Bioeng Biotechnol. 2019 Mar 26;7:56. doi: 10.3389/fbioe.2019.00056. eCollection 2019. Review.

3.

Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis.

Pickering RJ, Tikellis C, Rosado CJ, Tsorotes D, Dimitropoulos A, Smith M, Huet O, Seeber RM, Abhayawardana R, Johnstone EK, Golledge J, Wang Y, Jandeleit-Dahm KA, Cooper ME, Pfleger KD, Thomas MC.

J Clin Invest. 2019 Jan 2;129(1):406-421. doi: 10.1172/JCI99987. Epub 2018 Dec 10.

4.

NanoBRET ligand binding at a GPCR under endogenous promotion facilitated by CRISPR/Cas9 genome editing.

White CW, Johnstone EKM, See HB, Pfleger KDG.

Cell Signal. 2019 Feb;54:27-34. doi: 10.1016/j.cellsig.2018.11.018. Epub 2018 Nov 22.

PMID:
30471466
5.

BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes.

O'Brien SL, Johnstone EKM, Devost D, Conroy J, Reichelt ME, Purdue BW, Ayoub MA, Kawai T, Inoue A, Eguchi S, H├ębert TE, Pfleger KDG, Thomas WG.

Biochem Pharmacol. 2018 Dec;158:232-242. doi: 10.1016/j.bcp.2018.10.017. Epub 2018 Oct 19.

PMID:
30347205
6.

Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time.

White CW, Vanyai HK, See HB, Johnstone EKM, Pfleger KDG.

Sci Rep. 2017 Jun 9;7(1):3187. doi: 10.1038/s41598-017-03486-2.

7.

Bioluminescence Resonance Energy Transfer Approaches to Discover Bias in GPCR Signaling.

Johnstone EK, Pfleger KD.

Methods Mol Biol. 2015;1335:191-204. doi: 10.1007/978-1-4939-2914-6_13.

PMID:
26260602
8.

Application of BRET to monitor ligand binding to GPCRs.

Stoddart LA, Johnstone EKM, Wheal AJ, Goulding J, Robers MB, Machleidt T, Wood KV, Hill SJ, Pfleger KDG.

Nat Methods. 2015 Jul;12(7):661-663. doi: 10.1038/nmeth.3398. Epub 2015 Jun 1.

9.

Functional interaction between angiotensin II receptor type 1 and chemokine (C-C motif) receptor 2 with implications for chronic kidney disease.

Ayoub MA, Zhang Y, Kelly RS, See HB, Johnstone EK, McCall EA, Williams JH, Kelly DJ, Pfleger KD.

PLoS One. 2015 Mar 25;10(3):e0119803. doi: 10.1371/journal.pone.0119803. eCollection 2015.

10.

Receptor-Heteromer Investigation Technology and its application using BRET.

Johnstone EK, Pfleger KD.

Front Endocrinol (Lausanne). 2012 Aug 22;3:101. doi: 10.3389/fendo.2012.00101. eCollection 2012.

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