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Items: 1 to 50 of 56

1.

Chasing Tails: Cathepsin-L Improves Structural Analysis of Histones by HX-MS.

Papanastasiou M, Mullahoo J, DeRuff KC, Bajrami B, Karageorgos I, Johnston SE, Peckner R, Myers SA, Carr SA, Jaffe JD.

Mol Cell Proteomics. 2019 Oct;18(10):2089-2098. doi: 10.1074/mcp.RA119.001325. Epub 2019 Aug 13.

PMID:
31409669
2.

Conservation of the structure and function of bacterial tryptophan synthases.

Michalska K, Gale J, Joachimiak G, Chang C, Hatzos-Skintges C, Nocek B, Johnston SE, Bigelow L, Bajrami B, Jedrzejczak RP, Wellington S, Hung DT, Nag PP, Fisher SL, Endres M, Joachimiak A.

IUCrJ. 2019 May 29;6(Pt 4):649-664. doi: 10.1107/S2052252519005955. eCollection 2019 Jul 1.

3.

Evolutionary stasis of a heritable morphological trait in a wild fish population despite apparent directional selection.

O'Sullivan RJ, Aykanat T, Johnston SE, Kane A, Poole R, Rogan G, Prodöhl PA, Primmer CR, McGinnity P, Reed TE.

Ecol Evol. 2019 Jun 11;9(12):7096-7111. doi: 10.1002/ece3.5274. eCollection 2019 Jun.

4.

Associations of biological stress markers in hurricane survivors: Heartrate variability, Interleukin-2 and Interleukin-6 in depression and PTSD.

Tucker P, Pfefferbaum B, Zhao YD, Johnston SE, Mistry A, Khan QS.

Am J Disaster Med. 2018 Fall;13(4):267-278. doi: 10.5055/ajdm.2018.0306.

PMID:
30821340
5.

Home ground advantage: Local Atlantic salmon have higher reproductive fitness than dispersers in the wild.

Mobley KB, Granroth-Wilding H, Ellmen M, Vähä JP, Aykanat T, Johnston SE, Orell P, Erkinaro J, Primmer CR.

Sci Adv. 2019 Feb 27;5(2):eaav1112. doi: 10.1126/sciadv.aav1112. eCollection 2019 Feb.

6.

Novel tricyclic glycal-based TRIB1 inducers that reprogram LDL metabolism in hepatic cells.

Nagiec MM, Duvall JR, Skepner AP, Howe EA, Bastien J, Comer E, Marie JC, Johnston SE, Negri J, Eichhorn M, Vantourout J, Clish C, Musunuru K, Foley M, Perez JR, Palmer MAJ.

Medchemcomm. 2018 Sep 14;9(11):1831-1842. doi: 10.1039/c8md00297e. eCollection 2018 Nov 1.

7.

Natural Selection on Antihelminth Antibodies in a Wild Mammal Population.

Sparks AM, Watt K, Sinclair R, Pilkington JG, Pemberton JM, Johnston SE, McNeilly TN, Nussey DH.

Am Nat. 2018 Dec;192(6):745-760. doi: 10.1086/700115. Epub 2018 Oct 10.

PMID:
30444657
8.
9.

Correction to 'Variation in recombination frequency and distribution across eukaryotes: patterns and processes'.

Stapley J, Feulner PGD, Johnston SE, Santure AW, Smadja CM.

Philos Trans R Soc Lond B Biol Sci. 2018 Feb 5;373(1739). pii: 20170360. doi: 10.1098/rstb.2017.0360. No abstract available.

10.

Recombination: the good, the bad and the variable.

Stapley J, Feulner PGD, Johnston SE, Santure AW, Smadja CM.

Philos Trans R Soc Lond B Biol Sci. 2017 Dec 19;372(1736). pii: 20170279. doi: 10.1098/rstb.2017.0279.

11.

Variation in recombination frequency and distribution across eukaryotes: patterns and processes.

Stapley J, Feulner PGD, Johnston SE, Santure AW, Smadja CM.

Philos Trans R Soc Lond B Biol Sci. 2017 Dec 19;372(1736). pii: 20160455. doi: 10.1098/rstb.2016.0455. Review. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2018 Feb 5;373(1739):null.

12.

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine.

Geller LT, Barzily-Rokni M, Danino T, Jonas OH, Shental N, Nejman D, Gavert N, Zwang Y, Cooper ZA, Shee K, Thaiss CA, Reuben A, Livny J, Avraham R, Frederick DT, Ligorio M, Chatman K, Johnston SE, Mosher CM, Brandis A, Fuks G, Gurbatri C, Gopalakrishnan V, Kim M, Hurd MW, Katz M, Fleming J, Maitra A, Smith DA, Skalak M, Bu J, Michaud M, Trauger SA, Barshack I, Golan T, Sandbank J, Flaherty KT, Mandinova A, Garrett WS, Thayer SP, Ferrone CR, Huttenhower C, Bhatia SN, Gevers D, Wargo JA, Golub TR, Straussman R.

Science. 2017 Sep 15;357(6356):1156-1160. doi: 10.1126/science.aah5043.

13.

Erratum: Structural and conformational determinants of macrocycle cell permeability.

Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MWD, Duvall JR, Kihlberg J.

Nat Chem Biol. 2017 Jul 18;13(8):922. doi: 10.1038/nchembio0817-922a. No abstract available.

PMID:
28853740
14.

The potential of shifting recombination hotspots to increase genetic gain in livestock breeding.

Gonen S, Battagin M, Johnston SE, Gorjanc G, Hickey JM.

Genet Sel Evol. 2017 Jul 4;49(1):55. doi: 10.1186/s12711-017-0330-5.

15.

A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.

Wellington S, Nag PP, Michalska K, Johnston SE, Jedrzejczak RP, Kaushik VK, Clatworthy AE, Siddiqi N, McCarren P, Bajrami B, Maltseva NI, Combs S, Fisher SL, Joachimiak A, Schreiber SL, Hung DT.

Nat Chem Biol. 2017 Sep;13(9):943-950. doi: 10.1038/nchembio.2420. Epub 2017 Jul 3.

PMID:
28671682
16.

A High-Density Linkage Map Reveals Sexual Dimorphism in Recombination Landscapes in Red Deer (Cervus elaphus).

Johnston SE, Huisman J, Ellis PA, Pemberton JM.

G3 (Bethesda). 2017 Aug 7;7(8):2859-2870. doi: 10.1534/g3.117.044198.

17.

The Drug Repurposing Hub: a next-generation drug library and information resource.

Corsello SM, Bittker JA, Liu Z, Gould J, McCarren P, Hirschman JE, Johnston SE, Vrcic A, Wong B, Khan M, Asiedu J, Narayan R, Mader CC, Subramanian A, Golub TR.

Nat Med. 2017 Apr 7;23(4):405-408. doi: 10.1038/nm.4306. No abstract available.

18.

Discovery of Compounds that Positively Modulate the High Affinity Choline Transporter.

Choudhary P, Armstrong EJ, Jorgensen CC, Piotrowski M, Barthmes M, Torella R, Johnston SE, Maruyama Y, Janiszewski JS, Storer RI, Skerratt SE, Benn CL.

Front Mol Neurosci. 2017 Feb 27;10:40. doi: 10.3389/fnmol.2017.00040. eCollection 2017.

19.

Discovery of 8-Membered Ring Sulfonamides as Inhibitors of Oncogenic Mutant Isocitrate Dehydrogenase 1.

Law JM, Stark SC, Liu K, Liang NE, Hussain MM, Leiendecker M, Ito D, Verho O, Stern AM, Johnston SE, Zhang YL, Dunn GP, Shamji AF, Schreiber SL.

ACS Med Chem Lett. 2016 Aug 18;7(10):944-949. eCollection 2016 Oct 13.

20.

Structural and conformational determinants of macrocycle cell permeability.

Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MW, Duvall JR, Kihlberg J.

Nat Chem Biol. 2016 Dec;12(12):1065-1074. doi: 10.1038/nchembio.2203. Epub 2016 Oct 17. Erratum in: Nat Chem Biol. 2017 Jul 18;13(8):922.

PMID:
27748751
21.

Evolutionary mysteries in meiosis.

Lenormand T, Engelstädter J, Johnston SE, Wijnker E, Haag CR.

Philos Trans R Soc Lond B Biol Sci. 2016 Oct 19;371(1706). pii: 20160001. doi: 10.1098/rstb.2016.0001. Review.

22.

Effect of manipulating recombination rates on response to selection in livestock breeding programs.

Battagin M, Gorjanc G, Faux AM, Johnston SE, Hickey JM.

Genet Sel Evol. 2016 Jun 22;48(1):44. doi: 10.1186/s12711-016-0221-1.

23.

Angle closure glaucoma in the Northern Ireland Diabetic Retinopathy Screening Programme.

Lagan MA, O'Gallagher MK, Johnston SE, Hart PM.

Eye (Lond). 2016 Aug;30(8):1091-3. doi: 10.1038/eye.2016.98. Epub 2016 May 27.

24.

Conserved Genetic Architecture Underlying Individual Recombination Rate Variation in a Wild Population of Soay Sheep (Ovis aries).

Johnston SE, Bérénos C, Slate J, Pemberton JM.

Genetics. 2016 May;203(1):583-98. doi: 10.1534/genetics.115.185553. Epub 2016 Mar 30.

25.

Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon.

Barson NJ, Aykanat T, Hindar K, Baranski M, Bolstad GH, Fiske P, Jacq C, Jensen AJ, Johnston SE, Karlsson S, Kent M, Moen T, Niemelä E, Nome T, Næsje TF, Orell P, Romakkaniemi A, Sægrov H, Urdal K, Erkinaro J, Lien S, Primmer CR.

Nature. 2015 Dec 17;528(7582):405-8. doi: 10.1038/nature16062. Epub 2015 Nov 4.

PMID:
26536110
26.

Low but significant genetic differentiation underlies biologically meaningful phenotypic divergence in a large Atlantic salmon population.

Aykanat T, Johnston SE, Orell P, Niemelä E, Erkinaro J, Primmer CR.

Mol Ecol. 2015 Oct;24(20):5158-74. doi: 10.1111/mec.13383. Epub 2015 Oct 12.

PMID:
26363183
27.

Genome-wide SNP analysis reveals a genetic basis for sea-age variation in a wild population of Atlantic salmon (Salmo salar).

Johnston SE, Orell P, Pritchard VL, Kent MP, Lien S, Niemelä E, Erkinaro J, Primmer CR.

Mol Ecol. 2014 Jul;23(14):3452-68. doi: 10.1111/mec.12832.

PMID:
24931807
28.

Molecular pedigree reconstruction and estimation of evolutionary parameters in a wild Atlantic salmon river system with incomplete sampling: a power analysis.

Aykanat T, Johnston SE, Cotter D, Cross TF, Poole R, Prodőhl PA, Reed T, Rogan G, McGinnity P, Primmer CR.

BMC Evol Biol. 2014 Mar 31;14(1):68. doi: 10.1186/1471-2148-14-68.

29.

Life history trade-offs at a single locus maintain sexually selected genetic variation.

Johnston SE, Gratten J, Berenos C, Pilkington JG, Clutton-Brock TH, Pemberton JM, Slate J.

Nature. 2013 Oct 3;502(7469):93-5. doi: 10.1038/nature12489. Epub 2013 Aug 21.

PMID:
23965625
30.

Fish scales and SNP chips: SNP genotyping and allele frequency estimation in individual and pooled DNA from historical samples of Atlantic salmon (Salmo salar).

Johnston SE, Lindqvist M, Niemelä E, Orell P, Erkinaro J, Kent MP, Lien S, Vähä JP, Vasemägi A, Primmer CR.

BMC Genomics. 2013 Jul 3;14:439. doi: 10.1186/1471-2164-14-439.

31.

Antibiotics for early onset neonatal infection.

Johnston SE, Anthony M.

Arch Dis Child Fetal Neonatal Ed. 2013 Mar;98(2):F184-5. doi: 10.1136/archdischild-2012-303071. Epub 2012 Oct 27. No abstract available.

PMID:
23104987
32.

Molecular evolutionary and population genomic analysis of the nine-spined stickleback using a modified restriction-site-associated DNA tag approach.

Bruneaux M, Johnston SE, Herczeg G, Merilä J, Primmer CR, Vasemägi A.

Mol Ecol. 2013 Feb;22(3):565-82. doi: 10.1111/j.1365-294X.2012.05749.x. Epub 2012 Sep 3.

PMID:
22943747
33.

Genome-wide association mapping identifies the genetic basis of discrete and quantitative variation in sexual weaponry in a wild sheep population.

Johnston SE, McEwan JC, Pickering NK, Kijas JW, Beraldi D, Pilkington JG, Pemberton JM, Slate J.

Mol Ecol. 2011 Jun;20(12):2555-66. doi: 10.1111/j.1365-294X.2011.05076.x. Epub 2011 Mar 29.

PMID:
21651634
34.

Self-management support: a new approach still anchored in an old model of health care.

Johnston SE, Liddy CE, Ives SM.

Can J Public Health. 2011 Jan-Feb;102(1):68-72.

PMID:
21485969
36.

Genome mapping in intensively studied wild vertebrate populations.

Slate J, Santure AW, Feulner PG, Brown EA, Ball AD, Johnston SE, Gratten J.

Trends Genet. 2010 Jun;26(6):275-84. doi: 10.1016/j.tig.2010.03.005. Epub 2010 May 3.

PMID:
20444518
37.

Horn type and horn length genes map to the same chromosomal region in Soay sheep.

Johnston SE, Beraldi D, McRae AF, Pemberton JM, Slate J.

Heredity (Edinb). 2010 Feb;104(2):196-205. doi: 10.1038/hdy.2009.109. Epub 2009 Aug 19.

38.

Butterfly speciation and the distribution of gene effect sizes fixed during adaptation.

Baxter SW, Johnston SE, Jiggins CD.

Heredity (Edinb). 2009 Jan;102(1):57-65. doi: 10.1038/hdy.2008.109. Epub 2008 Nov 5. Review.

39.

Development of a conductivity-based photothermal absorbance detector for capillary separations.

Johnston SE, Fadgen KE, Jorgenson JW.

Anal Chem. 2006 Aug 1;78(15):5309-15.

PMID:
16878864
40.

Penetrating ocular injuries from fish-hooks.

Knox FA, Chan WC, McAvoy CE, Johnston SE, Bryars JH.

Int Ophthalmol. 2004 Oct-Dec;25(5-6):291-4. Epub 2006 Mar 7.

PMID:
16532292
41.

Expanded electrical model of a contactless conductivity detector: development and verification.

Johnston SE, Fadgen KE, Tolley LT, Jorgenson JW.

J Chromatogr A. 2005 Nov 11;1094(1-2):148-57. Epub 2005 Aug 18.

PMID:
16257301
42.

Preventing alcohol-related harm in college students: Alcohol-related Harm Prevention program effects on hypothesized mediating variables.

Graham JW, Tatterson JW, Roberts MM, Johnston SE.

Health Educ Res. 2004 Feb;19(1):71-84.

PMID:
15020547
43.

Data quality in evaluation of an alcohol-related harm prevention program.

Graham JW, Roberts MM, Tatterson JW, Johnston SE.

Eval Rev. 2002 Apr;26(2):147-89.

PMID:
11949537
44.

Medical professionalism: another view.

Cruess SR, Cruess RL, Johnston SE.

Health Aff (Millwood). 2001 Jan-Feb;20(1):309. No abstract available.

PMID:
11194858
45.

Monitoring electroosmotic flow by periodic photobleaching of a dilute, neutral fluorophore

Schrum KF, Lancaster JM 3rd, Johnston SE, Gilman SD.

Anal Chem. 2000 Sep 15;72(18):4317-21.

PMID:
11008766
46.

Professionalism: an ideal to be sustained.

Cruess RL, Cruess SR, Johnston SE.

Lancet. 2000 Jul 8;356(9224):156-9. Review. No abstract available.

PMID:
10963262
47.

Professionalism and medicine's social contract.

Cruess RL, Cruess SR, Johnston SE.

J Bone Joint Surg Am. 2000 Aug;82(8):1189-94. No abstract available.

PMID:
10954108
48.

Capillary electrophoretic analysis of alkaline phosphatase inhibition by theophylline.

Whisnant AR, Johnston SE, Gilman SD.

Electrophoresis. 2000 Apr;21(7):1341-8.

PMID:
10826679
49.

Renewing professionalism: an opportunity for medicine.

Cruess RL, Cruess SR, Johnston SE.

Acad Med. 1999 Aug;74(8):878-84.

PMID:
10495726
50.

Using a computerized scheduling system to predict procedure lengths.

Bross B, Gamblin BB, Holtzclaw SL, Johnston SE.

AORN J. 1995 Jun;61(6):1054-6, 1059-61.

PMID:
7632049

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