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Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma.

Massey SC, White H, Whitmire P, Doyle T, Johnston SK, Singleton KW, Jackson PR, Hawkins-Daarud A, Bendok BR, Porter AB, Vora S, Sarkaria JN, Hu LS, Mrugala MM, Swanson KR.

PLoS One. 2020 Mar 27;15(3):e0230492. doi: 10.1371/journal.pone.0230492. eCollection 2020.


Cytoplasmic Cyclin E Is an Independent Marker of Aggressive Tumor Biology and Breast Cancer-Specific Mortality in Women over 70 Years of Age.

Johnston SJ, Syed BM, Parks RM, Monteiro CJ, Caruso JA, Green AR, Ellis IO, Hunt KK, Karakas C, Keyomarsi K, Cheung KL.

Cancers (Basel). 2020 Mar 18;12(3). pii: E712. doi: 10.3390/cancers12030712.


Antibody characterization using immunosignatures.

Stafford P, Johnston SA, Kantarci OH, Zare-Shahabadi A, Warrington A, Rodriguez M.

PLoS One. 2020 Mar 20;15(3):e0229080. doi: 10.1371/journal.pone.0229080. eCollection 2020.


The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils.

Prajsnar TK, Serba JJ, Dekker BM, Gibson JF, Masud S, Fleming A, Johnston SA, Renshaw SA, Meijer AH.

Autophagy. 2020 Mar 15:1-15. doi: 10.1080/15548627.2020.1739443. [Epub ahead of print]


Block, engaged? The impact of three-dimensional printed anatomical models on first-year student engagement in a block-mode delivery.

Tripodi N, Kelly K, Husaric M, Wospil R, Fleischmann M, Johnston S, Harkin K.

Anat Sci Educ. 2020 Mar 12. doi: 10.1002/ase.1958. [Epub ahead of print]


Effects of team sports on anxiety, depression, perceived stress, and sleep quality in college students.

Johnston SA, Roskowski C, He Z, Kong L, Chen W.

J Am Coll Health. 2020 Mar 9:1-7. doi: 10.1080/07448481.2019.1707836. [Epub ahead of print]


Characterization of all-terrain vehicle-related thoracolumbar spine injury patterns in children using the AOSpine classification system.

Jordan RW Jr, Beckmann NM, Johnston JH, Johnston SK, Zhang X, Chinapuvvula NR.

Emerg Radiol. 2020 Feb 26. doi: 10.1007/s10140-020-01762-9. [Epub ahead of print]


From cells to tissue: How cell scale heterogeneity impacts glioblastoma growth and treatment response.

Gallaher JA, Massey SC, Hawkins-Daarud A, Noticewala SS, Rockne RC, Johnston SK, Gonzalez-Cuyar L, Juliano J, Gil O, Swanson KR, Canoll P, Anderson ARA.

PLoS Comput Biol. 2020 Feb 26;16(2):e1007672. doi: 10.1371/journal.pcbi.1007672. eCollection 2020 Feb.


Association of Black Race With Early Recurrence After Minor Ischemic Stroke or Transient Ischemic Attack: Secondary Analysis of the POINT Randomized Clinical Trial.

Kamel H, Zhang C, Kleindorfer DO, Levitan EB, Howard VJ, Howard G, Soliman EZ, Johnston SC.

JAMA Neurol. 2020 Feb 24. doi: 10.1001/jamaneurol.2020.0010. [Epub ahead of print]


Towards personalization of asthma treatment according to trigger factors.

Niespodziana K, Borochova K, Pazderova P, Schlederer T, Astafyeva N, Baranovskaya T, Barbouche MR, Beltiukov E, Berger A, Borzova E, Bousquet J, Bumbacea RS, Bychkovskaya S, Caraballo L, Chung KF, Custovic A, Docena G, Eiwegger T, Evsegneeva I, Emelyanov A, Errhalt P, Fassakhov R, Fayzullina R, Fedenko E, Fomina D, Gao Z, Giavina-Bianchi P, Gotua M, Greber-Platzer S, Hedlin G, Ilina N, Ispayeva Z, Idzko M, Johnston SL, Kalayci Ö, Karaulov A, Karsonova A, Khaitov M, Kovzel E, Kowalski ML, Kudlay D, Levin M, Makarova S, Matricardi PM, Nadeau KC, Namazova-Baranova L, Naumova O, Nazarenko O, O Byrne PM, Osier F, Pampura AN, Panaitescu C, Papadopoulos NG, Park HS, Pawankar R, Pohl W, Renz H, Riabova K, Sampath V, Sekerel BE, Sibanda E, Siroux V, Sizyakina LP, Sun JL, Szepfalusi Z, Umanets T, Van Bever HPS, van Hage M, Vasileva M, von Mutius E, Wang JY, Wong GWK, Zaikov S, Zidarn M, Valenta R.

J Allergy Clin Immunol. 2020 Feb 17. pii: S0091-6749(20)30193-7. doi: 10.1016/j.jaci.2020.02.001. [Epub ahead of print]


Disability After Minor Stroke and Transient Ischemic Attack in the POINT Trial.

Cucchiara B, Elm J, Easton JD, Coutts SB, Willey JZ, Biros MH, Ross MA, Johnston SC.

Stroke. 2020 Mar;51(3):792-799. doi: 10.1161/STROKEAHA.119.027465. Epub 2020 Feb 12.


The parent and child experience of childhood vitiligo: An interpretative phenomenological analysis.

Moss K, Johnston SA, Thompson AR.

Clin Child Psychol Psychiatry. 2020 Feb 17:1359104520905052. doi: 10.1177/1359104520905052. [Epub ahead of print]


Implications of New Understandings of Gliomas in Children and Adults with NF1: Report of a Consensus Conference.

Packer RJ, Iavarone A, Jones DTW, Blakeley JO, Bouffet E, Fisher MJ, Hwang E, Hawkins C, Kilburn L, MacDonald T, Pfister SM, Rood B, Rodriguez FJ, Tabori U, Ramaswamy V, Zhu Y, Fangusaro J, Johnston SA, Gutmann DH.

Neuro Oncol. 2020 Feb 14. pii: noaa036. doi: 10.1093/neuonc/noaa036. [Epub ahead of print]


Health costs of post-operative complications following rectal resection: a systematic review.

Johnston S, Louis M, Churilov L, Ma R, Christophi C, Weinberg L.

ANZ J Surg. 2020 Feb 13. doi: 10.1111/ans.15708. [Epub ahead of print] Review.


Antimony and arsenic speciation, redox-cycling and contrasting mobility in a mining-impacted river system.

Johnston SG, Bennett WW, Doriean N, Hockmann K, Karimian N, Burton ED.

Sci Total Environ. 2020 Mar 25;710:136354. doi: 10.1016/j.scitotenv.2019.136354. Epub 2020 Jan 3.


Correction to: Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer.

Pancholi S, Leal MF, Ribas R, Simigdala N, Schuster E, Chateau-Joubert S, Zabaglo L, Hills M, Dodson A, Gao Q, Johnston SR, Dowsett M, Cosulich SC, Marangoni E, Martin LA.

Breast Cancer Res. 2020 Jan 31;22(1):14. doi: 10.1186/s13058-020-1254-5.


The incidence and etiology of sperm DNA fragmentation in the ejaculates of males with spinal cord injuries.

Vargas-Baquero E, Johnston S, Sánchez-Ramos A, Arévalo-Martín A, Wilson R, Gosálvez J.

Spinal Cord. 2020 Jan 30. doi: 10.1038/s41393-020-0426-6. [Epub ahead of print]


Surgical Treatment of Tethered Cord Syndrome in Adults: A Systematic Review and Meta-Analysis.

O'Connor KP, Smitherman AD, Milton CK, Palejwala AH, Lu VM, Johnston SE, Homburg H, Zhao D, Martin MD.

World Neurosurg. 2020 Jan 28. pii: S1878-8750(20)30149-2. doi: 10.1016/j.wneu.2020.01.131. [Epub ahead of print]


Higher early recurrence risk and potential benefit of dual antiplatelet therapy for minor stroke with watershed infarction: subgroup analysis of CHANCE.

Pu Y, Liu X, Wang Y, Meng X, Jing J, Zou X, Pan Y, Wang A, Zhao X, Johnston SC, Wang Y, Atchaneeyasakul K, Liebeskind DS, Liu L; CHANCE Investigators.

Eur J Neurol. 2020 Jan 29. doi: 10.1111/ene.14156. [Epub ahead of print]


Health-related quality of life in patients with myalgic encephalomyelitis/chronic fatigue syndrome: an Australian cross-sectional study.

Eaton-Fitch N, Johnston SC, Zalewski P, Staines D, Marshall-Gradisnik S.

Qual Life Res. 2020 Jan 22. doi: 10.1007/s11136-019-02411-6. [Epub ahead of print]


Long-term impact of inhaled corticosteroid use in asthma and chronic obstructive pulmonary disease (COPD): Review of mechanisms that underlie risks.

Singanayagam A, Johnston SL.

J Allergy Clin Immunol. 2020 Jan 14. pii: S0091-6749(20)30029-4. doi: 10.1016/j.jaci.2019.12.907. [Epub ahead of print] No abstract available.


Developing priorities to achieve health equity through diabetes translation research: a concept mapping study.

Phad A, Johnston S, Tabak RG, Mazzucca S, Haire-Joshu D.

BMJ Open Diabetes Res Care. 2019 Dec 11;7(1):e000851. doi: 10.1136/bmjdrc-2019-000851. eCollection 2019.


Impulsive decision-making and gambling severity: The influence of γ-amino-butyric acid (GABA) and glutamate-glutamine (Glx).

Weidacker K, Johnston SJ, Mullins PG, Boy F, Dymond S.

Eur Neuropsychopharmacol. 2020 Mar;32:36-46. doi: 10.1016/j.euroneuro.2019.12.110. Epub 2019 Dec 31.


Value in Primary Healthcare - Measuring What Matters?

Wong ST, Johnston S, Burge F, McGrail K.

Healthc Pap. 2019 Dec;18(4):58-67. doi: 10.12927/hcpap.2019.26028.


Lp-PLA2 and dual antiplatelet agents in intracranial arterial stenosis.

Yang M, Wang A, Li J, Zhao X, Liu L, Meng X, Jing J, Zhang N, Johnston SC, Wang Y, Wang Y.

Neurology. 2020 Jan 14;94(2):e181-e189. doi: 10.1212/WNL.0000000000008733. Epub 2019 Dec 10.


Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection.

Guvenel A, Jozwik A, Ascough S, Ung SK, Paterson S, Kalyan M, Gardener Z, Bergstrom E, Kar S, Habibi MS, Paras A, Zhu J, Park M, Dhariwal J, Almond M, Wong EH, Sykes A, Del Rosario J, Trujillo-Torralbo MB, Mallia P, Sidney J, Peters B, Kon OM, Sette A, Johnston SL, Openshaw PJ, Chiu C.

J Clin Invest. 2020 Jan 2;130(1):523-538. doi: 10.1172/JCI131696.


Co-incubation of spermatozoa with human follicular fluid reduces sperm DNA fragmentation by mitigating DNase activity in the seminal plasma.

Dorado-Silva M, Bartolomé-Nebreda J, Sánchez-Martín P, Johnston S, Gosálvez J.

J Assist Reprod Genet. 2020 Jan;37(1):63-69. doi: 10.1007/s10815-019-01643-2. Epub 2019 Dec 5.


Gaze direction reveals implicit item and source memory in older adults.

Antón-Méndez I, Talk A, Johnston S.

PLoS One. 2019 Dec 5;14(12):e0226018. doi: 10.1371/journal.pone.0226018. eCollection 2019.


Combination of mTORC1/2 inhibitor vistusertib plus fulvestrant in vitro and in vivo targets oestrogen receptor-positive endocrine-resistant breast cancer.

Pancholi S, Leal MF, Ribas R, Simigdala N, Schuster E, Chateau-Joubert S, Zabaglo L, Hills M, Dodson A, Gao Q, Johnston SR, Dowsett M, Cosulich SC, Maragoni E, Martin LA.

Breast Cancer Res. 2019 Dec 4;21(1):135. doi: 10.1186/s13058-019-1222-0. Erratum in: Breast Cancer Res. 2020 Jan 31;22(1):14.


Author Correction: RNA Transcription and Splicing Errors as a Source of Cancer Frameshift Neoantigens for Vaccines.

Shen L, Zhang J, Lee H, Batista MT, Johnston SA.

Sci Rep. 2019 Nov 25;9(1):17815. doi: 10.1038/s41598-019-54300-0.


Comparison of Cardiovascular Risk Factors and Outcomes Among Practicing Physicians vs the General Population in Ontario, Canada.

Ko DT, Chu A, Austin PC, Johnston S, Nallamothu BK, Roifman I, Tusevljak N, Udell JA, Frank E.

JAMA Netw Open. 2019 Nov 1;2(11):e1915983. doi: 10.1001/jamanetworkopen.2019.15983.


Author Correction: Entropy is a Simple Measure of the Antibody Profile and is an Indicator of Health Status: A Proof of Concept.

Wang L, Whittemore K, Johnston SA, Stafford P.

Sci Rep. 2019 Nov 22;9(1):17645. doi: 10.1038/s41598-019-54235-6.


Autonomic adaptations mediate the effect of hydration on brain functioning and mood: Evidence from two randomized controlled trials.

Young HA, Cousins A, Johnston S, Fletcher JM, Benton D.

Sci Rep. 2019 Nov 11;9(1):16412. doi: 10.1038/s41598-019-52775-5.


The genetic architecture of helminth-specific immune responses in a wild population of Soay sheep (Ovis aries).

Sparks AM, Watt K, Sinclair R, Pilkington JG, Pemberton JM, McNeilly TN, Nussey DH, Johnston SE.

PLoS Genet. 2019 Nov 7;15(11):e1008461. doi: 10.1371/journal.pgen.1008461. eCollection 2019 Nov.


Individual variation of the masticatory system dominates 3D skull shape in the herbivory-adapted marsupial wombats.

Weisbecker V, Guillerme T, Speck C, Sherratt E, Abraha HM, Sharp AC, Terhune CE, Collins S, Johnston S, Panagiotopoulou O.

Front Zool. 2019 Nov 1;16:41. doi: 10.1186/s12983-019-0338-5. eCollection 2019.


The radial and ulnar collateral ligaments of the wrist are true ligaments.

Türker T, Sheppard JE, Klauser AS, Johnston SS, Amerongen H, Taljanovic MS.

Diagn Interv Radiol. 2019 Nov;25(6):473-479. doi: 10.5152/dir.2019.19036.


Abnormal pulmonary function tests are associated with prolonged ventilation and risk of complications following elective cardiac surgery.

Reddi BA, Johnston SD, Bart S, Chan JC, Finnis M.

Anaesth Intensive Care. 2019 Nov;47(6):510-515. doi: 10.1177/0310057X19877188. Epub 2019 Oct 24. No abstract available.


Advances in Endocrine-Based Therapies for Estrogen Receptor-Positive Metastatic Breast Cancer.

Aggelis V, Johnston SRD.

Drugs. 2019 Nov;79(17):1849-1866. doi: 10.1007/s40265-019-01208-8. Review.


Regional variation in primary care improvement strategies and policy: case studies that consider qualitative contextual data for performance measurement in three Canadian provinces.

Martin-Misener R, Wong ST, Johnston S, Blackman S, Scott C, Hogg W, Burge F, Grool AM, Campbell JL, Wuite S.

BMJ Open. 2019 Oct 17;9(10):e029622. doi: 10.1136/bmjopen-2019-029622.


The piRNA Response to Retroviral Invasion of the Koala Genome.

Yu T, Koppetsch BS, Pagliarani S, Johnston S, Silverstein NJ, Luban J, Chappell K, Weng Z, Theurkauf WE.

Cell. 2019 Oct 17;179(3):632-643.e12. doi: 10.1016/j.cell.2019.09.002. Epub 2019 Oct 10.


Locally instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps.

Radermecker C, Sabatel C, Vanwinge C, Ruscitti C, Maréchal P, Perin F, Schyns J, Rocks N, Toussaint M, Cataldo D, Johnston SL, Bureau F, Marichal T.

Nat Immunol. 2019 Nov;20(11):1444-1455. doi: 10.1038/s41590-019-0496-9. Epub 2019 Oct 7.


Inactivating NF1 Mutations Are Enriched in Advanced Breast Cancer and Contribute to Endocrine Therapy Resistance.

Pearson A, Proszek P, Pascual J, Fribbens C, Shamsher MK, Kingston B, O'Leary B, Herrera-Abreu MT, Cutts RJ, Garcia-Murillas I, Bye H, Walker BA, Gonzalez De Castro D, Yuan L, Jamal S, Hubank M, Lopez-Knowles E, Schuster EF, Dowsett M, Osin P, Nerurkar A, Parton M, Okines AFC, Johnston SRD, Ring A, Turner NC.

Clin Cancer Res. 2020 Feb 1;26(3):608-622. doi: 10.1158/1078-0432.CCR-18-4044. Epub 2019 Oct 7.


RNA Transcription and Splicing Errors as a Source of Cancer Frameshift Neoantigens for Vaccines.

Shen L, Zhang J, Lee H, Batista MT, Johnston SA.

Sci Rep. 2019 Oct 2;9(1):14184. doi: 10.1038/s41598-019-50738-4. Erratum in: Sci Rep. 2019 Nov 25;9(1):17815.


IFN Therapy in Airway Disease: Is Prophylaxis a New Approach in Exacerbation Prevention?

Johnston SL.

Am J Respir Crit Care Med. 2020 Jan 1;201(1):9-11. doi: 10.1164/rccm.201909-1850ED. No abstract available.


The Risk and Cost of Limited Clinician and Patient Accountability in Health Care.

Johnston SC.

JAMA. 2019 Sep 30. doi: 10.1001/jama.2019.14832. [Epub ahead of print] No abstract available.


The Effect of Abemaciclib Plus Fulvestrant on Overall Survival in Hormone Receptor-Positive, ERBB2-Negative Breast Cancer That Progressed on Endocrine Therapy-MONARCH 2: A Randomized Clinical Trial.

Sledge GW Jr, Toi M, Neven P, Sohn J, Inoue K, Pivot X, Burdaeva O, Okera M, Masuda N, Kaufman PA, Koh H, Grischke EM, Conte P, Lu Y, Barriga S, Hurt K, Frenzel M, Johnston S, Llombart-Cussac A.

JAMA Oncol. 2019 Sep 29. doi: 10.1001/jamaoncol.2019.4782. [Epub ahead of print]


Association of Rotavirus Vaccination With Inpatient and Emergency Department Visits Among Children Seeking Care for Acute Gastroenteritis, 2010-2016.

Payne DC, Englund JA, Weinberg GA, Halasa NB, Boom JA, Staat MA, Selvarangan R, Azimi PH, Klein EJ, Szilagyi PG, Chappell J, Sahni LC, McNeal M, Harrison CJ, Moffatt ME, Johnston SH, Mijatovic-Rustempasic S, Esona MD, Tate JE, Curns AT, Wikswo ME, Sulemana I, Bowen MD, Parashar UD.

JAMA Netw Open. 2019 Sep 4;2(9):e1912242. doi: 10.1001/jamanetworkopen.2019.12242.


Spontaneous, Grassroots Initiative Brings Niagara Health's New Purpose, Vision and Values to Life.

Rolim D, Wiley CB, Kerrigan S, MacDonald S, Traynor S, Paladino F, Johnston S, Viljoen J.

Healthc Q. 2019 Jul;22(2):68-74. doi: 10.12927/hcq.2019.25901.


Infectious Causes of Acute Gastroenteritis in US Children Undergoing Allogeneic Hematopoietic Cell Transplant: A Longitudinal, Multicenter Study.

Schuster JE, Johnston SH, Piya B, Dulek DE, Wikswo ME, McHenry R, Browne H, Gautam R, Bowen MD, Vinjé J, Payne DC, Azimi P, Selvarangan R, Halasa N, Englund JA.

J Pediatric Infect Dis Soc. 2019 Sep 24. pii: piz063. doi: 10.1093/jpids/piz063. [Epub ahead of print]


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