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Items: 1 to 50 of 79

1.

Efficacy of an intermittent energy restriction diet in a primary care setting.

Antoni R, Johnston KL, Steele C, Carter D, Robertson MD, Capehorn MS.

Eur J Nutr. 2019 Oct 11. doi: 10.1007/s00394-019-02098-y. [Epub ahead of print]

PMID:
31605198
2.

Using formative evaluation methods to improve clinical implementation efforts: Description and an example.

Elwy AR, Wasan AD, Gillman AG, Johnston KL, Dodds N, McFarland C, Greco CM.

Psychiatry Res. 2019 Aug 26:112532. doi: 10.1016/j.psychres.2019.112532. [Epub ahead of print]

PMID:
31477261
3.

Development of a High-Throughput Cytometric Screen to Identify Anti- Wolbachia Compounds: The Power of Public-Private Partnership.

Clare RH, Clark R, Bardelle C, Harper P, Collier M, Johnston KL, Plant H, Plant D, McCall E, Slatko BE, Cantin L, Wu B, Ford L, Murray D, Rich K, Wigglesworth M, Taylor MJ, Ward SA.

SLAS Discov. 2019 Jun;24(5):537-547. doi: 10.1177/2472555219838341. Epub 2019 Apr 8.

4.

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis.

Taylor MJ, von Geldern TW, Ford L, Hübner MP, Marsh K, Johnston KL, Sjoberg HT, Specht S, Pionnier N, Tyrer HE, Clare RH, Cook DAN, Murphy E, Steven A, Archer J, Bloemker D, Lenz F, Koschel M, Ehrens A, Metuge HM, Chunda VC, Ndongmo Chounna PW, Njouendou AJ, Fombad FF, Carr R, Morton HE, Aljayyoussi G, Hoerauf A, Wanji S, Kempf DJ, Turner JD, Ward SA.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau2086. doi: 10.1126/scitranslmed.aau2086.

PMID:
30867321
5.

Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity.

von Geldern TW, Morton HE, Clark RF, Brown BS, Johnston KL, Ford L, Specht S, Carr RA, Stolarik DF, Ma J, Rieser MJ, Struever D, Frohberger SJ, Koschel M, Ehrens A, Turner JD, Hübner MP, Hoerauf A, Taylor MJ, Ward SA, Marsh K, Kempf DJ.

PLoS Negl Trop Dis. 2019 Feb 28;13(2):e0007159. doi: 10.1371/journal.pntd.0007159. eCollection 2019 Feb.

6.

Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.

Jacobs RT, Lunde CS, Freund YR, Hernandez V, Li X, Xia Y, Carter DS, Berry PW, Halladay J, Rock F, Stefanakis R, Easom E, Plattner JJ, Ford L, Johnston KL, Cook DAN, Clare R, Cassidy A, Myhill L, Tyrer H, Gamble J, Guimaraes AF, Steven A, Lenz F, Ehrens A, Frohberger SJ, Koschel M, Hoerauf A, Hübner MP, McNamara CW, Bakowski MA, Turner JD, Taylor MJ, Ward SA.

J Med Chem. 2019 Mar 14;62(5):2521-2540. doi: 10.1021/acs.jmedchem.8b01854. Epub 2019 Feb 26.

7.

Screening for Personality Disorders: A Three-Item Screener From the Inventory of Interpersonal Problems (IIP-3).

Pilkonis PA, Lawrence SM, Johnston KL, Dodds NE.

J Pers Disord. 2019 Jan 16:1-14. doi: 10.1521/pedi_2019_33_369. [Epub ahead of print]

PMID:
30650003
8.

AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.

Hong WD, Benayoud F, Nixon GL, Ford L, Johnston KL, Clare RH, Cassidy A, Cook DAN, Siu A, Shiotani M, Webborn PJH, Kavanagh S, Aljayyoussi G, Murphy E, Steven A, Archer J, Struever D, Frohberger SJ, Ehrens A, Hübner MP, Hoerauf A, Roberts AP, Hubbard ATM, Tate EW, Serwa RA, Leung SC, Qie L, Berry NG, Gusovsky F, Hemingway J, Turner JD, Taylor MJ, Ward SA, O'Neill PM.

Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419. doi: 10.1073/pnas.1816585116. Epub 2019 Jan 7.

9.

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides.

Clare RH, Bardelle C, Harper P, Hong WD, Börjesson U, Johnston KL, Collier M, Myhill L, Cassidy A, Plant D, Plant H, Clark R, Cook DAN, Steven A, Archer J, McGillan P, Charoensutthivarakul S, Bibby J, Sharma R, Nixon GL, Slatko BE, Cantin L, Wu B, Turner J, Ford L, Rich K, Wigglesworth M, Berry NG, O'Neill PM, Taylor MJ, Ward SA.

Nat Commun. 2019 Jan 2;10(1):11. doi: 10.1038/s41467-018-07826-2.

10.

Intermittent v. continuous energy restriction: differential effects on postprandial glucose and lipid metabolism following matched weight loss in overweight/obese participants.

Antoni R, Johnston KL, Collins AL, Robertson MD.

Br J Nutr. 2018 Mar;119(5):507-516. doi: 10.1017/S0007114517003890.

PMID:
29508693
11.

Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA.

Sci Rep. 2018 Jan 18;8(1):1384. doi: 10.1038/s41598-018-19723-1.

12.

Corrigendum: Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

Sharma R, Aljayyoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DAN, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ.

Sci Rep. 2018 Jan 8;8:46934. doi: 10.1038/srep46934.

13.

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.

Turner JD, Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Priestley RS, Murphy EA, Davies J, Waterhouse D, Cook DAN, Clare RH, Cassidy A, Steven A, Johnston KL, McCall J, Ford L, Hemingway J, Ward SA, Taylor MJ.

Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9712-E9721. doi: 10.1073/pnas.1710845114. Epub 2017 Oct 23.

14.

The Olin EILOBI Breathing Techniques: Description and Initial Case Series of Novel Respiratory Retraining Strategies for Athletes with Exercise-Induced Laryngeal Obstruction.

Johnston KL, Bradford H, Hodges H, Moore CM, Nauman E, Olin JT.

J Voice. 2018 Nov;32(6):698-704. doi: 10.1016/j.jvoice.2017.08.020. Epub 2017 Oct 16.

PMID:
29050661
15.

Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library.

Johnston KL, Cook DAN, Berry NG, David Hong W, Clare RH, Goddard M, Ford L, Nixon GL, O'Neill PM, Ward SA, Taylor MJ.

Sci Adv. 2017 Sep 27;3(9):eaao1551. doi: 10.1126/sciadv.aao1551. eCollection 2017 Sep.

16.

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.

Aljayyoussi G, Tyrer HE, Ford L, Sjoberg H, Pionnier N, Waterhouse D, Davies J, Gamble J, Metuge H, Cook DAN, Steven A, Sharma R, Guimaraes AF, Clare RH, Cassidy A, Johnston KL, Myhill L, Hayward L, Wanji S, Turner JD, Taylor MJ, Ward SA.

Sci Rep. 2017 Mar 16;7(1):210. doi: 10.1038/s41598-017-00322-5. Erratum in: Sci Rep. 2018 Jan 18;8(1):1384.

17.

Effects of intermittent fasting on glucose and lipid metabolism.

Antoni R, Johnston KL, Collins AL, Robertson MD.

Proc Nutr Soc. 2017 Aug;76(3):361-368. doi: 10.1017/S0029665116002986. Epub 2017 Jan 16. Review.

PMID:
28091348
18.

Therapeutic laryngoscopy during exercise: A novel non-surgical therapy for refractory EILO.

Olin JT, Deardorff EH, Fan EM, Johnston KL, Keever VL, Moore CM, Bender BG.

Pediatr Pulmonol. 2017 Jun;52(6):813-819. doi: 10.1002/ppul.23634. Epub 2016 Oct 31.

PMID:
27797458
19.

Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis.

Tamarozzi F, Turner JD, Pionnier N, Midgley A, Guimaraes AF, Johnston KL, Edwards SW, Taylor MJ.

Sci Rep. 2016 Oct 18;6:35559. doi: 10.1038/srep35559.

20.

The experiences of women with polycystic ovary syndrome on a very low-calorie diet.

Love JG, McKenzie JS, Nikokavoura EA, Broom J, Rolland C, Johnston KL.

Int J Womens Health. 2016 Jul 21;8:299-310. doi: 10.2147/IJWH.S100385. eCollection 2016.

21.

Continuous laryngoscopy quantitates laryngeal behaviour in exercise and recovery.

Olin JT, Clary MS, Fan EM, Johnston KL, State CM, Strand M, Christopher KL.

Eur Respir J. 2016 Oct;48(4):1192-1200. doi: 10.1183/13993003.00160-2016. Epub 2016 Jul 13.

22.

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.

Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DA, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ.

Sci Rep. 2016 Mar 21;6:23458. doi: 10.1038/srep23458. Erratum in: Sci Rep. 2018 Jan 08;8:46934.

23.

Validation of the alcohol use item banks from the Patient-Reported Outcomes Measurement Information System (PROMIS).

Pilkonis PA, Yu L, Dodds NE, Johnston KL, Lawrence SM, Daley DC.

Drug Alcohol Depend. 2016 Apr 1;161:316-22. doi: 10.1016/j.drugalcdep.2016.02.014. Epub 2016 Feb 17.

24.

Clinical validity of PROMIS Depression, Anxiety, and Anger across diverse clinical samples.

Schalet BD, Pilkonis PA, Yu L, Dodds N, Johnston KL, Yount S, Riley W, Cella D.

J Clin Epidemiol. 2016 May;73:119-27. doi: 10.1016/j.jclinepi.2015.08.036. Epub 2016 Feb 27.

25.

Investigation into the acute effects of total and partial energy restriction on postprandial metabolism among overweight/obese participants.

Antoni R, Johnston KL, Collins AL, Robertson MD.

Br J Nutr. 2016 Mar 28;115(6):951-9. doi: 10.1017/S0007114515005346. Epub 2016 Jan 28.

PMID:
26819200
26.

An Item Bank for Abuse of Prescription Pain Medication from the Patient-Reported Outcomes Measurement Information System (PROMIS®).

Pilkonis PA, Yu L, Dodds NE, Johnston KL, Lawrence SM, Hilton TF, Daley DC, Patkar AA, McCarty D.

Pain Med. 2017 Aug 1;18(8):1516-1527. doi: 10.1093/pm/pnw233.

27.

Measuring nonspecific factors in treatment: item banks that assess the healthcare experience and attitudes from the patient's perspective.

Greco CM, Yu L, Johnston KL, Dodds NE, Morone NE, Glick RM, Schneider MJ, Klem ML, McFarland CE, Lawrence S, Colditz J, Maihoefer CC, Jonas WB, Ryan ND, Pilkonis PA.

Qual Life Res. 2016 Jul;25(7):1625-34. doi: 10.1007/s11136-015-1178-1. Epub 2015 Nov 12.

28.

Weight loss for women with and without polycystic ovary syndrome following a very low-calorie diet in a community-based setting with trained facilitators for 12 weeks.

Nikokavoura EA, Johnston KL, Broom J, Wrieden WL, Rolland C.

Diabetes Metab Syndr Obes. 2015 Oct 14;8:495-503. doi: 10.2147/DMSO.S85134. eCollection 2015.

29.

Item banks for substance use from the Patient-Reported Outcomes Measurement Information System (PROMIS(®)): Severity of use and positive appeal of use.

Pilkonis PA, Yu L, Dodds NE, Johnston KL, Lawrence SM, Hilton TF, Daley DC, Patkar AA, McCarty D.

Drug Alcohol Depend. 2015 Nov 1;156:184-192. doi: 10.1016/j.drugalcdep.2015.09.008. Epub 2015 Sep 21. Erratum in: Drug Alcohol Depend. 2016 Feb 1;159:285-6.

30.

Evaluating PROMIS® instruments and methods for patient-centered outcomes research: Patient and provider voices in a substance use treatment setting.

Johnston KL, Lawrence SM, Dodds NE, Yu L, Daley DC, Pilkonis PA.

Qual Life Res. 2016 Mar;25(3):615-24. doi: 10.1007/s11136-015-1131-3. Epub 2015 Sep 9.

31.

The cost-effectiveness of the LighterLife weight management programme as an intervention for obesity in England.

Lewis L, Taylor M, Broom J, Johnston KL.

Clin Obes. 2014 Jun;4(3):180-8. doi: 10.1111/cob.12060. Epub 2014 May 7.

PMID:
25826774
32.

Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis.

Johnston KL, Ford L, Umareddy I, Townson S, Specht S, Pfarr K, Hoerauf A, Altmeyer R, Taylor MJ.

Int J Parasitol Drugs Drug Resist. 2014 Sep 16;4(3):278-86. doi: 10.1016/j.ijpddr.2014.09.001. eCollection 2014 Dec.

33.
34.

Development and validation of a high-throughput anti-Wolbachia whole-cell screen: a route to macrofilaricidal drugs against onchocerciasis and lymphatic filariasis.

Clare RH, Cook DA, Johnston KL, Ford L, Ward SA, Taylor MJ.

J Biomol Screen. 2015 Jan;20(1):64-9. doi: 10.1177/1087057114551518. Epub 2014 Oct 2.

PMID:
25278497
35.

Validation of the depression item bank from the Patient-Reported Outcomes Measurement Information System (PROMIS) in a three-month observational study.

Pilkonis PA, Yu L, Dodds NE, Johnston KL, Maihoefer CC, Lawrence SM.

J Psychiatr Res. 2014 Sep;56:112-9. doi: 10.1016/j.jpsychires.2014.05.010. Epub 2014 May 29.

36.

Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro.

Tamarozzi F, Wright HL, Johnston KL, Edwards SW, Turner JD, Taylor MJ.

Parasite Immunol. 2014 Oct;36(10):494-502. doi: 10.1111/pim.12122.

37.

Absence of Wolbachia endobacteria in the human parasitic nematode Dracunculus medinensis and two related Dracunculus species infecting wildlife.

Foster JM, Landmann F, Ford L, Johnston KL, Elsasser SC, Schulte-Hostedde AI, Taylor MJ, Slatko BE.

Parasit Vectors. 2014 Mar 31;7:140. doi: 10.1186/1756-3305-7-140.

38.

Long-term weight loss maintenance and management following a VLCD: a 3-year outcome.

Rolland C, Johnston KL, Lula S, Macdonald I, Broom J.

Int J Clin Pract. 2014 Mar;68(3):379-87. doi: 10.1111/ijcp.12300. Epub 2013 Dec 22.

PMID:
24372837
39.

Overcoming the challenges of drug discovery for neglected tropical diseases: the A·WOL experience.

Johnston KL, Ford L, Taylor MJ.

J Biomol Screen. 2014 Mar;19(3):335-43. doi: 10.1177/1087057113511270. Epub 2013 Nov 15. Review.

PMID:
24241712
40.

The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review.

Rolland C, Mavroeidi A, Johnston KL, Broom J.

Diabetes Metab Syndr Obes. 2013 Oct 11;6:393-401. doi: 10.2147/DMSO.S51151. eCollection 2013.

41.

Weight loss for individuals with type 2 diabetes following a very-low-calorie diet in a community-based setting with trained facilitators for 12 weeks.

Rolland C, Lula S, Jenner C, Dyson L, Macdonald I, Johnston KL, Broom I.

Clin Obes. 2013 Oct;3(5):150-7. doi: 10.1111/cob.12029. Epub 2013 Aug 23.

PMID:
25586630
42.

Extensively duplicated and transcriptionally active recent lateral gene transfer from a bacterial Wolbachia endosymbiont to its host filarial nematode Brugia malayi.

Ioannidis P, Johnston KL, Riley DR, Kumar N, White JR, Olarte KT, Ott S, Tallon LJ, Foster JM, Taylor MJ, Dunning Hotopp JC.

BMC Genomics. 2013 Sep 22;14:639. doi: 10.1186/1471-2164-14-639.

43.

Requirement of lipid II biosynthesis for cell division in cell wall-less Wolbachia, endobacteria of arthropods and filarial nematodes.

Vollmer J, Schiefer A, Schneider T, Jülicher K, Johnston KL, Taylor MJ, Sahl HG, Hoerauf A, Pfarr K.

Int J Med Microbiol. 2013 Apr;303(3):140-9. doi: 10.1016/j.ijmm.2013.01.002. Epub 2013 Mar 19.

PMID:
23517690
44.

Wolbachia filarial interactions.

Taylor MJ, Voronin D, Johnston KL, Ford L.

Cell Microbiol. 2013 Apr;15(4):520-6. doi: 10.1111/cmi.12084. Epub 2012 Dec 24. Review.

PMID:
23210448
45.

Item banks for alcohol use from the Patient-Reported Outcomes Measurement Information System (PROMIS): use, consequences, and expectancies.

Pilkonis PA, Yu L, Colditz J, Dodds N, Johnston KL, Maihoefer C, Stover AM, Daley DC, McCarty D.

Drug Alcohol Depend. 2013 Jun 1;130(1-3):167-77. doi: 10.1016/j.drugalcdep.2012.11.002. Epub 2012 Dec 1.

46.

Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo.

Schiefer A, Schmitz A, Schäberle TF, Specht S, Lämmer C, Johnston KL, Vassylyev DG, König GM, Hoerauf A, Pfarr K.

J Infect Dis. 2012 Jul 15;206(2):249-57. doi: 10.1093/infdis/jis341. Epub 2012 May 14.

47.

Development of short forms from the PROMIS™ sleep disturbance and Sleep-Related Impairment item banks.

Yu L, Buysse DJ, Germain A, Moul DE, Stover A, Dodds NE, Johnston KL, Pilkonis PA.

Behav Sleep Med. 2011 Dec 28;10(1):6-24. doi: 10.1080/15402002.2012.636266.

48.

The effect of ready-to-eat cereal consumption on energy intake, body weight and anthropometric measurements: results from a randomized, controlled intervention trial.

Matthews A, Hull S, Angus F, Johnston KL.

Int J Food Sci Nutr. 2012 Feb;63(1):107-13. doi: 10.3109/09637486.2011.602052. Epub 2011 Jul 21.

PMID:
21777054
49.

Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes.

Johnston KL, Wu B, Guimarães A, Ford L, Slatko BE, Taylor MJ.

Parasit Vectors. 2010 Oct 14;3:99. doi: 10.1186/1756-3305-3-99.

50.

Development and validation of patient-reported outcome measures for sleep disturbance and sleep-related impairments.

Buysse DJ, Yu L, Moul DE, Germain A, Stover A, Dodds NE, Johnston KL, Shablesky-Cade MA, Pilkonis PA.

Sleep. 2010 Jun;33(6):781-92.

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