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A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.

Sin-Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, Du Y, Lu M, Patel N, Torchia J, Popovski D, Fouladi M, Guilhamon P, Hansford JR, Leary S, Hoffman LM, Mulcahy Levy JM, Lassaletta A, Solano-Paez P, Rivas E, Reddy A, Gillespie GY, Gupta N, Van Meter TE, Nakamura H, Wong TT, Ra YS, Kim SK, Massimi L, Grundy RG, Fangusaro J, Johnston D, Chan J, Lafay-Cousin L, Hwang EI, Wang Y, Catchpoole D, Michaud J, Ellezam B, Ramanujachar R, Lindsay H, Taylor MD, Hawkins CE, Bouffet E, Jabado N, Singh SK, Kleinman CL, Barsyte-Lovejoy D, Li XN, Dirks PB, Lin CY, Mack SC, Rich JN, Huang A.

Cancer Cell. 2019 Jul 8;36(1):51-67.e7. doi: 10.1016/j.ccell.2019.06.002.


Review of Cases of Angiostrongyliasis in Hawaii, 2007-2017.

Johnston DI, Dixon MC, Elm JL, Calimlim PS, Sciulli RH, Park SY.

Am J Trop Med Hyg. 2019 Jul 8. doi: 10.4269/ajtmh.19-0280. [Epub ahead of print]


The relationship between depression symptoms, absenteeism and presenteeism.

Johnston DA, Harvey SB, Glozier N, Calvo RA, Christensen H, Deady M.

J Affect Disord. 2019 Jun 30;256:536-540. doi: 10.1016/j.jad.2019.06.041. [Epub ahead of print]


Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment.

Butler AA, Johnston DR, Kaur S, Lubin FD.

Sci Signal. 2019 Jul 2;12(588). pii: eaaw9277. doi: 10.1126/scisignal.aaw9277.


Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.

Fedoriw A, Rajapurkar SR, O'Brien S, Gerhart SV, Mitchell LH, Adams ND, Rioux N, Lingaraj T, Ribich SA, Pappalardi MB, Shah N, Laraio J, Liu Y, Butticello M, Carpenter CL, Creasy C, Korenchuk S, McCabe MT, McHugh CF, Nagarajan R, Wagner C, Zappacosta F, Annan R, Concha NO, Thomas RA, Hart TK, Smith JJ, Copeland RA, Moyer MP, Campbell J, Stickland K, Mills J, Jacques-O'Hagan S, Allain C, Johnston D, Raimondi A, Porter Scott M, Waters N, Swinger K, Boriack-Sjodin A, Riera T, Shapiro G, Chesworth R, Prinjha RK, Kruger RG, Barbash O, Mohammad HP.

Cancer Cell. 2019 Jul 8;36(1):100-114.e25. doi: 10.1016/j.ccell.2019.05.014. Epub 2019 Jun 27.


Risk of adding prophylactic aorta replacement to a cardiac operation.

Idrees JJ, Roselli EE, Blackstone EH, Lowry AM, Soltesz EG, Johnston DR, Tong MZ, Pettersson GB, Griffin B, Gillinov AM, Svensson LG.

J Thorac Cardiovasc Surg. 2019 May 18. pii: S0022-5223(19)31039-6. doi: 10.1016/j.jtcvs.2019.05.001. [Epub ahead of print]


Pilot Test of a Computer-Based System to Help Family Caregivers of Dementia Patients.

Gustafson DH, Gustafson DH, Cody OJ, Chih MY, Johnston DC, Asthana S.

J Alzheimers Dis. 2019 Jun 24. doi: 10.3233/JAD-190052. [Epub ahead of print]


Metabolic health and vascular complications in type 1 diabetes.

Bhattarai S, Godsland IF, Misra S, Johnston DG, Oliver N.

J Diabetes Complications. 2019 Jun 7. pii: S1056-8727(18)31283-2. doi: 10.1016/j.jdiacomp.2019.05.026. [Epub ahead of print]


Quality of life in pediatric acute myeloid leukemia: Report from the Children's Oncology Group.

Nagarajan R, Gerbing R, Alonzo T, Johnston DL, Aplenc R, Kolb EA, Meshinchi S, Barakat LP, Sung L.

Cancer Med. 2019 Jun 12. doi: 10.1002/cam4.2337. [Epub ahead of print]


Accuracy of motor assessment in the diagnosis of fetal alcohol spectrum disorder.

Johnston D, Branton E, Rasmuson L, Schell S, Gross DP, Pritchard-Wiart L.

BMC Pediatr. 2019 May 28;19(1):171. doi: 10.1186/s12887-019-1542-3.


Radiation-Associated Cardiac Disease: More Complicated Than Just Transcatheter Replacement of the Aortic Valve.

Desai MY, Johnston DR, Svensson LG.

Cardiovasc Revasc Med. 2019 May;20(5):369-370. doi: 10.1016/j.carrev.2019.03.015. No abstract available.


Differences in management outcome for first branchial cleft anomalies: A comparison of infants and toddlers to older children.

Brown LA, Johnston DR, Rastatter J, Sweis BM, Maddalozzo J.

Int J Pediatr Otorhinolaryngol. 2019 Jul;122:161-164. doi: 10.1016/j.ijporl.2019.04.009. Epub 2019 Apr 11.


The Bone Phenotype and Pain Response to Pamidronate in Tyrosine Kinase Inhibitor-Treated Chronic Myelogenous Leukemia.

Lavoie DCT, Robinson ME, Johnston D, Pagé M, Konji VN, Rauch F, Ward LM.

J Endocr Soc. 2019 Mar 11;3(5):857-864. doi: 10.1210/js.2018-00268. eCollection 2019 May 1.


Presacral Medulloepithelioma: Case Report and Literature Review.

Honnorat M, Al-Karmi S, Hawkins C, Johnston D, Gerstle T, Schechter T, Huang A, Bouffet E.

J Pediatr Hematol Oncol. 2019 Apr 15. doi: 10.1097/MPH.0000000000001460. [Epub ahead of print]


Microbiomes of Inflammatory Thoracic Aortic Aneurysms Due to Giant Cell Arteritis and Clinically Isolated Aortitis Differ From Those of Non-Inflammatory Aneurysms.

Getz TM, Hoffman GS, Padmanabhan R, Villa-Forte A, Roselli EE, Blackstone E, Johnston D, Pettersson G, Soltesz E, Svensson LG, Calabrese LH, Clifford AH, Eng C.

Pathog Immun. 2019 Mar 15;4(1):105-123. doi: 10.20411/pai.v4i1.269. eCollection 2019.


Multiprobe Nuclear Imaging of the Cystic Fibrosis Lung as a Biomarker of Therapeutic Effect.

Corcoran TE, Huber AS, Myerburg MM, Weiner DJ, Locke LW, Lacy RT, Weber L, Czachowski MR, Johnston DJ, Muthukrishnan A, Lennox AT, Pilewski JM.

J Aerosol Med Pulm Drug Deliv. 2019 Apr 10. doi: 10.1089/jamp.2018.1491. [Epub ahead of print]


Paediatric Endoscopy Global Rating Scale: Development of a Quality Improvement Tool and Results of a National Pilot.

Narula P, Broughton R, Howarth L, Piggott A, Bremner R, Tzivinikos C, Gillett P, Henderson P, Rawat D, Cullen M, Loganathan S, Devadason D, Afzal NA, Maginnis J, McKenna S, Thomson M, Green J, Johnston D.

J Pediatr Gastroenterol Nutr. 2019 Apr 1. doi: 10.1097/MPG.0000000000002355. [Epub ahead of print]


Epilepsy-Induced Reduction in HCN Channel Expression Contributes to an Increased Excitability in Dorsal, But Not Ventral, Hippocampal CA1 Neurons.

Arnold EC, McMurray C, Gray R, Johnston D.

eNeuro. 2019 Apr 2;6(2). pii: ENEURO.0036-19.2019. doi: 10.1523/ENEURO.0036-19.2019. eCollection 2019 Mar-Apr.


A Unique Case of a Pediatric Patient With Blastic Plasmacytoid Dendritic Cell Neoplasm, Guillain Barre Syndrome, and Hemophagocytic Lymphohistiocytosis.

Penney C, Johnston DL, Story E.

J Pediatr Hematol Oncol. 2019 Mar 29. doi: 10.1097/MPH.0000000000001464. [Epub ahead of print]


Deposition studies of aerosol delivery by nasal cannula to infants.

Corcoran TE, Saville A, Adams PS, Johnston DJ, Czachowski MR, Domnina YA, Lin JH, Weiner DJ, Huber AS, Sanchez De Toledo J, Lo CW.

Pediatr Pulmonol. 2019 Apr 1. doi: 10.1002/ppul.24326. [Epub ahead of print]


Hyperglycemia recognised in early pregnancy is phenotypically type 2 diabetes mellitus not gestational diabetes mellitus: a case control study.

Agha-Jaffar R, Oliver NS, Kostoula M, Godsland IF, Yu C, Terry J, Johnston D, Gable D, Robinson S.

J Matern Fetal Neonatal Med. 2019 Mar 26:1-7. doi: 10.1080/14767058.2019.1593959. [Epub ahead of print]


Targeting FER Kinase Inhibits Melanoma Growth and Metastasis.

Ivanova IA, Arulanantham S, Barr K, Cepeda M, Parkins KM, Hamilton AM, Johnston D, Penuela S, Hess DA, Ronald JA, Dagnino L.

Cancers (Basel). 2019 Mar 24;11(3). pii: E419. doi: 10.3390/cancers11030419.


Clinical decisions and time since rest break: An analysis of decision fatigue in nurses.

Allan JL, Johnston DW, Powell DJH, Farquharson B, Jones MC, Leckie G, Johnston M.

Health Psychol. 2019 Apr;38(4):318-324. doi: 10.1037/hea0000725.


Descriptive Epidemiology of New Zealand's Highest Mortality Earthquake: Hawke's Bay in 1931.

Clement C, Abeling S, Deely J, Teng A, Thomson G, Johnston D, Wilson N.

Sci Rep. 2019 Mar 20;9(1):4914. doi: 10.1038/s41598-019-41432-6.


Cadaveric findings of the effect of rib fractures on spread of serratus plane injections.

Johnston DF, Black ND, O'Halloran R, Turbitt LR, Taylor SJ.

Can J Anaesth. 2019 Jun;66(6):738-739. doi: 10.1007/s12630-019-01340-9. Epub 2019 Mar 7. No abstract available.


Oxidative Stress and Dysfunctional Intracellular Traffic Linked to an Unhealthy Diet Results in Impaired Cargo Transport in the Retinal Pigment Epithelium (RPE).

Keeling E, Chatelet DS, Johnston DA, Page A, Tumbarello DA, Lotery AJ, Ratnayaka JA.

Mol Nutr Food Res. 2019 Mar 5:e1800951. doi: 10.1002/mnfr.201800951. [Epub ahead of print]


The effect of re-audit and education on antibiotic prescribing practice at Causeway Hospital, Northern Ireland.

Johnston DN, Keshtkar F, Campbell W.

Ir J Med Sci. 2019 Feb 27. doi: 10.1007/s11845-019-01995-9. [Epub ahead of print]


Augmentation of Saporin-Based Immunotoxins for Human Leukaemia and Lymphoma Cells by Triterpenoid Saponins: The Modifying Effects of Small Molecule Pharmacological Agents.

Smith WS, Johnston DA, Holmes SE, Wensley HJ, Flavell SU, Flavell DJ.

Toxins (Basel). 2019 Feb 20;11(2). pii: E127. doi: 10.3390/toxins11020127.


Phase I dose-finding study for melatonin in pediatric oncology patients with relapsed solid tumors.

Johnston DL, Zupanec S, Nicksy D, Morgenstern D, Narendran A, Deyell RJ, Samson Y, Wu B, Baruchel S.

Pediatr Blood Cancer. 2019 Jun;66(6):e27676. doi: 10.1002/pbc.27676. Epub 2019 Feb 20.


Analysis of the retrograde tibial artery approach in lower extremity revascularization in an office endovascular center.

Lai SH, Fenlon J, Roush BB, Munn J, Rummel M, Johnston D, Longton C, Jain KM.

J Vasc Surg. 2019 Jul;70(1):157-165. doi: 10.1016/j.jvs.2018.10.114. Epub 2019 Feb 15.


Cannulation strategies in acute type A dissection repair: A systematic axillary artery approach.

Rosinski BF, Idrees JJ, Roselli EE, Germano E, Pasadyn SR, Lowry AM, Blackstone EH, Johnston DR, Soltesz EG, Navia JL, Desai MY, Mick SL, Bakaeen FG, Svensson LG.

J Thorac Cardiovasc Surg. 2018 Dec 19. pii: S0022-5223(18)33416-0. doi: 10.1016/j.jtcvs.2018.11.137. [Epub ahead of print]


Adult Patients With Marfan Syndrome and Ascending Aortic Surgery.

Desai MY, Kalahasti V, Hutt Centeno E, Chen K, Alashi A, Rivas CG, Roselli EE, Johnston DR, Griffin BP, Svensson LG.

J Am Coll Cardiol. 2019 Feb 19;73(6):733-734. doi: 10.1016/j.jacc.2018.12.010. No abstract available.


Rehabilitation after Hip Fracture for Nursing Home Residents: A Controlled Feasibility Trial.

Beaupre LA, Magaziner JS, Jones CA, Jhangri GS, Johnston DWC, Wilson DM, Majumdar SR.

J Gerontol A Biol Sci Med Sci. 2019 Feb 9. doi: 10.1093/gerona/glz031. [Epub ahead of print]


Radical Pericardiectomy for Pericardial Diseases.

Unai S, Johnston DR.

Curr Cardiol Rep. 2019 Feb 12;21(2):6. doi: 10.1007/s11886-019-1092-1. Review.


The Improving Quality in Liver Services accreditation scheme.

Ferguson J, Johnston D, Bano M.

Lancet Gastroenterol Hepatol. 2019 Mar;4(3):194. doi: 10.1016/S2468-1253(19)30003-2. No abstract available.


Outcomes among 196 patients with non-infectious proximal aortitis.

Clifford AH, Arafat A, Idrees JJ, Roselli EE, Tan CD, Rene Rodriguez E, Svensson LG, Blackstone E, Johnston D, Pettersson G, Soltesz E, Hoffman GS.

Arthritis Rheumatol. 2019 Feb 7. doi: 10.1002/art.40855. [Epub ahead of print]


Unmet needs in community-living persons with dementia are common, often non-medical and related to patient and caregiver characteristics.

Black BS, Johnston D, Leoutsakos J, Reuland M, Kelly J, Amjad H, Davis K, Willink A, Sloan D, Lyketsos C, Samus QM.

Int Psychogeriatr. 2019 Feb 4:1-12. doi: 10.1017/S1041610218002296. [Epub ahead of print]


Advances in managing the noninfected open chest after cardiac surgery: Negative-pressure wound therapy.

Bakaeen FG, Haddad O, Ibrahim M, Pasadyn SR, Germano E, Mok S, Halbreiner MS, McCurry KR, Johnston DR, Mick SL, Navia JL, Roselli EE, Smedira NG, Soltesz EG, Tong MZ, Wierup P, Gillinov AM, Svensson LG, Houghtaling PL, Blackstone EH, Pettersson GB.

J Thorac Cardiovasc Surg. 2019 May;157(5):1891-1903.e9. doi: 10.1016/j.jtcvs.2018.10.152. Epub 2018 Nov 27.


The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages.

Schulthess J, Pandey S, Capitani M, Rue-Albrecht KC, Arnold I, Franchini F, Chomka A, Ilott NE, Johnston DGW, Pires E, McCullagh J, Sansom SN, Arancibia-Cárcamo CV, Uhlig HH, Powrie F.

Immunity. 2019 Feb 19;50(2):432-445.e7. doi: 10.1016/j.immuni.2018.12.018. Epub 2019 Jan 23.


Fixed-Dose Subcutaneous C1-Inhibitor Liquid for Prophylactic Treatment of C1-INH-HAE: SAHARA Randomized Study.

Lumry WR, Martinez-Saguer I, Yang WH, Bernstein JA, Jacobs J, Moldovan D, Riedl MA, Johnston DT, Li HH, Tang Y, Schranz J, Lu P, Vardi M, Farkas H; SAHARA study group.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1610-1618.e4. doi: 10.1016/j.jaip.2019.01.021. Epub 2019 Jan 23.


Inhibition of Pannexin 1 Reduces the Tumorigenic Properties of Human Melanoma Cells.

Freeman TJ, Sayedyahossein S, Johnston D, Sanchez-Pupo RE, O'Donnell B, Huang K, Lakhani Z, Nouri-Nejad D, Barr KJ, Harland L, Latosinsky S, Grant A, Dagnino L, Penuela S.

Cancers (Basel). 2019 Jan 16;11(1). pii: E102. doi: 10.3390/cancers11010102.


Endoscopy in 2017: a national survey of practice in the UK.

Shenbagaraj L, Thomas-Gibson S, Stebbing J, Broughton R, Dron M, Johnston D, Shaw T, Haboubi HN, Green JT.

Frontline Gastroenterol. 2019 Jan;10(1):7-15. doi: 10.1136/flgastro-2018-100970. Epub 2018 Apr 24.


Spread of dye injectate in the distal femoral triangle versus the distal adductor canal: a cadaveric study.

Johnston DF, Black ND, Cowden R, Turbitt L, Taylor S.

Reg Anesth Pain Med. 2019 Jan;44(1):39-45. doi: 10.1136/rapm-2018-000002.


Deconstructing the Dissimilatory Sulfate Reduction Pathway: Isotope Fractionation of a Mutant Unable of Growth on Sulfate.

Bertran E, Leavitt WD, Pellerin A, Zane GM, Wall JD, Halevy I, Wing BA, Johnston DT.

Front Microbiol. 2018 Dec 14;9:3110. doi: 10.3389/fmicb.2018.03110. eCollection 2018.


Pharmacy students' opinions and experiences working on board the Transnet-Phelophepa Health Care Trains.

Johnston DMG, Truter I, Irwin YL, Naidoo P, Coetzee BC, Basson WD.

Int J Pharm Pract. 2019 Jun;27(3):311-317. doi: 10.1111/ijpp.12504. Epub 2018 Dec 28.


Trends and Outcomes of Cardiovascular Surgery in Patients With Opioid Use Disorders.

Dewan KC, Dewan KS, Idrees JJ, Navale SM, Rosinski BF, Svensson LG, Gillinov AM, Johnston DR, Bakaeen F, Soltesz EG.

JAMA Surg. 2018 Dec 5. doi: 10.1001/jamasurg.2018.4608. [Epub ahead of print]


Preliminary Effectiveness of a Smartphone App to Reduce Depressive Symptoms in the Workplace: Feasibility and Acceptability Study.

Deady M, Johnston D, Milne D, Glozier N, Peters D, Calvo R, Harvey S.

JMIR Mhealth Uhealth. 2018 Dec 4;6(12):e11661. doi: 10.2196/11661.


Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks: A Randomized Clinical Trial.

Banerji A, Riedl MA, Bernstein JA, Cicardi M, Longhurst HJ, Zuraw BL, Busse PJ, Anderson J, Magerl M, Martinez-Saguer I, Davis-Lorton M, Zanichelli A, Li HH, Craig T, Jacobs J, Johnston DT, Shapiro R, Yang WH, Lumry WR, Manning ME, Schwartz LB, Shennak M, Soteres D, Zaragoza-Urdaz RH, Gierer S, Smith AM, Tachdjian R, Wedner HJ, Hebert J, Rehman SM, Staubach P, Schranz J, Baptista J, Nothaft W, Maurer M; HELP Investigators.

JAMA. 2018 Nov 27;320(20):2108-2121. doi: 10.1001/jama.2018.16773. Erratum in: JAMA. 2019 Apr 23;321(16):1636.


Severely bothersome fatigue in children and adolescents with cancer and hematopoietic stem cell transplant recipients.

Tomlinson D, Baggott C, Dix D, Gibson P, Hyslop S, Johnston DL, Orsey A, Portwine C, Price V, Vanan M, Kuczynski S, Spiegler B, Tomlinson GA, Dupuis LL, Sung L.

Support Care Cancer. 2019 Jul;27(7):2665-2671. doi: 10.1007/s00520-018-4555-9. Epub 2018 Nov 26.


Chronic exposure of Hawaii Island spinner dolphins (Stenella longirostris) to human activities.

Tyne JA, Christiansen F, Heenehan HL, Johnston DW, Bejder L.

R Soc Open Sci. 2018 Oct 24;5(10):171506. doi: 10.1098/rsos.171506. eCollection 2018 Oct.

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