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Items: 1 to 50 of 131

1.

RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition.

Rackley L, Stewart JM, Salotti J, Krokhotin A, Shah A, Halman JR, Juneja R, Smollett J, Lee L, Roark K, Viard M, Tarannum M, Vivero-Escoto J, Johnson PF, Dobrovolskaia MA, Dokholyan NV, Franco E, Afonin KA.

Adv Funct Mater. 2018 Nov 28;28(48). pii: 1805959. doi: 10.1002/adfm.201805959. Epub 2018 Oct 9.

PMID:
31258458
2.

Localized RAS signaling drives cancer.

Basu SK, Basu S, Johnson PF.

Oncoscience. 2019 Apr 1;6(3-4):298-300. doi: 10.18632/oncoscience.479. eCollection 2019 Mar. No abstract available.

3.

C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer's disease.

Wang ZH, Gong K, Liu X, Zhang Z, Sun X, Wei ZZ, Yu SP, Manfredsson FP, Sandoval IM, Johnson PF, Jia J, Wang JZ, Ye K.

Nat Commun. 2018 May 3;9(1):1784. doi: 10.1038/s41467-018-04120-z.

4.

A RAS-CaMKKβ-AMPKα2 pathway promotes senescence by licensing post-translational activation of C/EBPβ through a novel 3'UTR mechanism.

Basu SK, Gonit M, Salotti J, Chen J, Bhat A, Gorospe M, Viollet B, Claffey KP, Johnson PF.

Oncogene. 2018 Jun;37(26):3528-3548. doi: 10.1038/s41388-018-0190-7. Epub 2018 Mar 22.

5.

IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.

Song NY, Zhu F, Wang Z, Willette-Brown J, Xi S, Sun Z, Su L, Wu X, Ma B, Nussinov R, Xia X, Schrump DS, Johnson PF, Karin M, Hu Y.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E812-E821. doi: 10.1073/pnas.1717520115. Epub 2018 Jan 8.

6.

Report of the SI2025 Task Force.

Duval JF, Opas LM, Nasca TJ, Johnson PF, Weiss KB.

J Grad Med Educ. 2017 Dec;9(6 Suppl):11-57. doi: 10.4300/1949-8349.9.6s.11. No abstract available.

7.

Oncogenic RAS-Induced Perinuclear Signaling Complexes Requiring KSR1 Regulate Signal Transmission to Downstream Targets.

Basu SK, Lee S, Salotti J, Basu S, Sakchaisri K, Xiao Z, Walia V, Westlake CJ, Morrison DK, Johnson PF.

Cancer Res. 2018 Feb 15;78(4):891-908. doi: 10.1158/0008-5472.CAN-17-2353. Epub 2017 Dec 19.

8.

Dual negative roles of C/EBPα in the expansion and pro-tumor functions of MDSCs.

Mackert JR, Qu P, Min Y, Johnson PF, Yang L, Lin PC.

Sci Rep. 2017 Oct 25;7(1):14048. doi: 10.1038/s41598-017-12968-2.

9.

Identification of senescent cell surface targetable protein DPP4.

Kim KM, Noh JH, Bodogai M, Martindale JL, Yang X, Indig FE, Basu SK, Ohnuma K, Morimoto C, Johnson PF, Biragyn A, Abdelmohsen K, Gorospe M.

Genes Dev. 2017 Aug 1;31(15):1529-1534. doi: 10.1101/gad.302570.117. Epub 2017 Sep 6.

10.

LPS independent activation of the pro-inflammatory receptor Trem1 by C/EBPε in granulocytes.

Suh HC, Benoukraf T, Shyamsunder P, Yin T, Cao Q, Said J, Lee S, Lim R, Yang H, Salotti J, Johnson PF, Madan V, Koeffler HP.

Sci Rep. 2017 Apr 25;7:46440. doi: 10.1038/srep46440.

11.

The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.

Ratner D, Orning MP, Proulx MK, Wang D, Gavrilin MA, Wewers MD, Alnemri ES, Johnson PF, Lee B, Mecsas J, Kayagaki N, Goguen JD, Lien E.

PLoS Pathog. 2016 Dec 2;12(12):e1006035. doi: 10.1371/journal.ppat.1006035. eCollection 2016 Dec.

12.

C/EBPγ Is a Critical Regulator of Cellular Stress Response Networks through Heterodimerization with ATF4.

Huggins CJ, Mayekar MK, Martin N, Saylor KL, Gonit M, Jailwala P, Kasoji M, Haines DC, Quiñones OA, Johnson PF.

Mol Cell Biol. 2015 Dec 14;36(5):693-713. doi: 10.1128/MCB.00911-15.

13.

An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer.

Salotti J, Sakchaisri K, Tourtellotte WG, Johnson PF.

Mol Cell Biol. 2015 Mar;35(5):866-83. doi: 10.1128/MCB.01489-14. Epub 2014 Dec 22.

14.

Structural insights into interactions of C/EBP transcriptional activators with the Taz2 domain of p300.

Bhaumik P, Davis J, Tropea JE, Cherry S, Johnson PF, Miller M.

Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1914-21. doi: 10.1107/S1399004714009262. Epub 2014 Jun 29.

15.

C/EBPγ suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPβ.

Huggins CJ, Malik R, Lee S, Salotti J, Thomas S, Martin N, Quiñones OA, Alvord WG, Olanich ME, Keller JR, Johnson PF.

Mol Cell Biol. 2013 Aug;33(16):3242-58. doi: 10.1128/MCB.01674-12. Epub 2013 Jun 17.

16.

Authors' reply.

Yan C, Tang H, Gao H, Johnson PF, Ye Y, Wu M.

Am J Pathol. 2013 Apr;182(4):1459-60. No abstract available.

PMID:
23614144
17.

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.

Wang X, Zhao Y, Zhang X, Badie H, Zhou Y, Mu Y, Loo LS, Cai L, Thompson RC, Yang B, Chen Y, Johnson PF, Wu C, Bu G, Mobley WC, Zhang D, Gage FH, Ranscht B, Zhang YW, Lipton SA, Hong W, Xu H.

Nat Med. 2013 Apr;19(4):473-80. doi: 10.1038/nm.3117. Epub 2013 Mar 24.

18.

CCAAT/enhancer-binding protein δ is a critical mediator of lipopolysaccharide-induced acute lung injury.

Yan C, Johnson PF, Tang H, Ye Y, Wu M, Gao H.

Am J Pathol. 2013 Feb;182(2):420-30. doi: 10.1016/j.ajpath.2012.10.013. Epub 2012 Nov 21.

19.

Critical role for CCAAT/enhancer-binding protein β in immune complex-induced acute lung injury.

Yan C, Wu M, Cao J, Tang H, Zhu M, Johnson PF, Gao H.

J Immunol. 2012 Aug 1;189(3):1480-90. doi: 10.4049/jimmunol.1200877. Epub 2012 Jun 25.

20.

CIKS/Act1-mediated signaling by IL-17 cytokines in context: implications for how a CIKS gene variant may predispose to psoriasis.

Sønder SU, Paun A, Ha HL, Johnson PF, Siebenlist U.

J Immunol. 2012 Jun 15;188(12):5906-14. doi: 10.4049/jimmunol.1103233. Epub 2012 May 11.

21.

C5a-regulated CCAAT/enhancer-binding proteins β and δ are essential in Fcγ receptor-mediated inflammatory cytokine and chemokine production in macrophages.

Yan C, Zhu M, Staiger J, Johnson PF, Gao H.

J Biol Chem. 2012 Jan 27;287(5):3217-30. doi: 10.1074/jbc.M111.280834. Epub 2011 Dec 6.

22.

Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells.

Sarkar TR, Sharan S, Wang J, Pawar SA, Cantwell CA, Johnson PF, Morrison DK, Wang JM, Sterneck E.

Mol Cell Biol. 2012 Jan;32(2):320-32. doi: 10.1128/MCB.05790-11. Epub 2011 Oct 28.

23.

3'UTR elements inhibit Ras-induced C/EBPβ post-translational activation and senescence in tumour cells.

Basu SK, Malik R, Huggins CJ, Lee S, Sebastian T, Sakchaisri K, Quiñones OA, Alvord WG, Johnson PF.

EMBO J. 2011 Jul 29;30(18):3714-28. doi: 10.1038/emboj.2011.250.

24.

A distal enhancer in Il12b is the target of transcriptional repression by the STAT3 pathway and requires the basic leucine zipper (B-ZIP) protein NFIL3.

Smith AM, Qualls JE, O'Brien K, Balouzian L, Johnson PF, Schultz-Cherry S, Smale ST, Murray PJ.

J Biol Chem. 2011 Jul 1;286(26):23582-90. doi: 10.1074/jbc.M111.249235. Epub 2011 May 12.

25.

CCAAT/enhancer-binding proteins (C/EBP)-α and -β are essential for ovulation, luteinization, and the expression of key target genes.

Fan HY, Liu Z, Johnson PF, Richards JS.

Mol Endocrinol. 2011 Feb;25(2):253-68. doi: 10.1210/me.2010-0318. Epub 2010 Dec 22.

26.

CCAAT/Enhancer-binding protein beta DNA binding is auto-inhibited by multiple elements that also mediate association with p300/CREB-binding protein (CBP).

Lee S, Miller M, Shuman JD, Johnson PF.

J Biol Chem. 2010 Jul 9;285(28):21399-410. doi: 10.1074/jbc.M110.128413. Epub 2010 May 7.

27.

RSK-mediated phosphorylation in the C/EBP{beta} leucine zipper regulates DNA binding, dimerization, and growth arrest activity.

Lee S, Shuman JD, Guszczynski T, Sakchaisri K, Sebastian T, Copeland TD, Miller M, Cohen MS, Taunton J, Smart RC, Xiao Z, Yu LR, Veenstra TD, Johnson PF.

Mol Cell Biol. 2010 Jun;30(11):2621-35. doi: 10.1128/MCB.00782-09. Epub 2010 Mar 29.

28.

A central role for transcription factor C/EBP-beta in regulating CD1d gene expression in human keratinocytes.

Sikder H, Zhao Y, Balato A, Chapoval A, Fishelevich R, Gade P, Singh IS, Kalvakolanu DV, Johnson PF, Gaspari AA.

J Immunol. 2009 Aug 1;183(3):1657-66. doi: 10.4049/jimmunol.0900057. Epub 2009 Jul 10. Erratum in: J Immunol. 2009 Sep 15;183(6):4135.

29.

MAPK3/1 (ERK1/2) in ovarian granulosa cells are essential for female fertility.

Fan HY, Liu Z, Shimada M, Sterneck E, Johnson PF, Hedrick SM, Richards JS.

Science. 2009 May 15;324(5929):938-41. doi: 10.1126/science.1171396.

30.
31.

C/EBPbeta regulates body composition, energy balance-related hormones and tumor growth.

Staiger J, Lueben MJ, Berrigan D, Malik R, Perkins SN, Hursting SD, Johnson PF.

Carcinogenesis. 2009 May;30(5):832-40. doi: 10.1093/carcin/bgn273. Epub 2008 Dec 4.

32.

The lamin B receptor under transcriptional control of C/EBPepsilon is required for morphological but not functional maturation of neutrophils.

Cohen TV, Klarmann KD, Sakchaisri K, Cooper JP, Kuhns D, Anver M, Johnson PF, Williams SC, Keller JR, Stewart CL.

Hum Mol Genet. 2008 Oct 1;17(19):2921-33. doi: 10.1093/hmg/ddn191. Epub 2008 Jul 11.

33.
34.

Transcriptional regulation of fatty acid translocase/CD36 expression by CCAAT/enhancer-binding protein alpha.

Qiao L, Zou C, Shao P, Schaack J, Johnson PF, Shao J.

J Biol Chem. 2008 Apr 4;283(14):8788-95. doi: 10.1074/jbc.M800055200. Epub 2008 Feb 8.

35.
36.

C/EBPbeta serine 64, a phosphoacceptor site, has a critical role in LPS-induced IL-6 and MCP-1 transcription.

Spooner CJ, Sebastian T, Shuman JD, Durairaj S, Guo X, Johnson PF, Schwartz RC.

Cytokine. 2007 Feb;37(2):119-27. Epub 2007 Apr 12.

PMID:
17433708
37.

5'UTR of the neurogenic bHLH Nex1/MATH-2/NeuroD6 gene is regulated by two distinct promoters through CRE and C/EBP binding sites.

Uittenbogaard M, Martinka DL, Johnson PF, Vinson C, Chiaramello A.

J Neurosci Res. 2007 Jan;85(1):1-18.

38.

A feedback transcriptional mechanism controls the level of the arginine/lysine transporter cat-1 during amino acid starvation.

Lopez AB, Wang C, Huang CC, Yaman I, Li Y, Chakravarty K, Johnson PF, Chiang CM, Snider MD, Wek RC, Hatzoglou M.

Biochem J. 2007 Feb 15;402(1):163-73.

39.

Decreased brain damage and curtailed inflammation in transcription factor CCAAT/enhancer binding protein beta knockout mice following transient focal cerebral ischemia.

Kapadia R, Tureyen K, Bowen KK, Kalluri H, Johnson PF, Vemuganti R.

J Neurochem. 2006 Sep;98(6):1718-31. Epub 2006 Aug 8.

40.

Differential roles of C/EBP beta regulatory domains in specifying MCP-1 and IL-6 transcription.

Spooner CJ, Guo X, Johnson PF, Schwartz RC.

Mol Immunol. 2007 Feb;44(6):1384-92. Epub 2006 Jun 19.

PMID:
16784777
41.

Stop and go: anti-proliferative and mitogenic functions of the transcription factor C/EBPbeta.

Sebastian T, Johnson PF.

Cell Cycle. 2006 May;5(9):953-7. Epub 2006 May 1. Review.

PMID:
16687924
42.

CAAT/enhancer-binding protein delta and cAMP-response element-binding protein mediate inducible expression of the nerve growth factor gene in the central nervous system.

McCauslin CS, Heath V, Colangelo AM, Malik R, Lee S, Mallei A, Mocchetti I, Johnson PF.

J Biol Chem. 2006 Jun 30;281(26):17681-8. Epub 2006 Apr 21.

43.

C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation.

Suh HC, Gooya J, Renn K, Friedman AD, Johnson PF, Keller JR.

Blood. 2006 Jun 1;107(11):4308-16. Epub 2006 Feb 9.

44.

C/EBPbeta is a critical mediator of steroid hormone-regulated cell proliferation and differentiation in the uterine epithelium and stroma.

Mantena SR, Kannan A, Cheon YP, Li Q, Johnson PF, Bagchi IC, Bagchi MK.

Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1870-5. Epub 2006 Jan 26.

45.

C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence.

Sebastian T, Malik R, Thomas S, Sage J, Johnson PF.

EMBO J. 2005 Sep 21;24(18):3301-12. Epub 2005 Aug 18.

46.

Molecular stop signs: regulation of cell-cycle arrest by C/EBP transcription factors.

Johnson PF.

J Cell Sci. 2005 Jun 15;118(Pt 12):2545-55. Review.

47.

A role for mixed lineage kinases in regulating transcription factor CCAAT/enhancer-binding protein-{beta}-dependent gene expression in response to interferon-{gamma}.

Roy SK, Shuman JD, Platanias LC, Shapiro PS, Reddy SP, Johnson PF, Kalvakolanu DV.

J Biol Chem. 2005 Jul 1;280(26):24462-71. Epub 2005 May 4.

48.

Repression of the inhibin alpha-subunit gene by the transcription factor CCAAT/enhancer-binding protein-beta.

Burkart AD, Mukherjee A, Sterneck E, Johnson PF, Mayo KE.

Endocrinology. 2005 Apr;146(4):1909-21. Epub 2005 Jan 13.

PMID:
15650079
49.

BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages.

Wessells J, Baer M, Young HA, Claudio E, Brown K, Siebenlist U, Johnson PF.

J Biol Chem. 2004 Nov 26;279(48):49995-50003. Epub 2004 Oct 1.

50.

Cell cycle-dependent phosphorylation of C/EBPbeta mediates oncogenic cooperativity between C/EBPbeta and H-RasV12.

Shuman JD, Sebastian T, Kaldis P, Copeland TD, Zhu S, Smart RC, Johnson PF.

Mol Cell Biol. 2004 Sep;24(17):7380-91.

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