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Items: 1 to 50 of 219

1.

Correction to: HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.

Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein-Szanto AJ, Nakagawa H, Basha J, Kundu T, Avadhani NG.

Cell Discov. 2019 May 14;5:28. doi: 10.1038/s41421-019-0097-7. eCollection 2019.

2.

Deletion of ULS1 confers damage tolerance in sgs1 mutants through a Top3-dependent D-loop mediated fork restart pathway.

Glineburg MR, Johns E, Johnson FB.

DNA Repair (Amst). 2019 Jun;78:102-113. doi: 10.1016/j.dnarep.2019.04.005. Epub 2019 Apr 13.

PMID:
31005681
3.

G-quadruplex dynamics contribute to regulation of mitochondrial gene expression.

Falabella M, Kolesar JE, Wallace C, de Jesus D, Sun L, Taguchi YV, Wang C, Wang T, Xiang IM, Alder JK, Maheshan R, Horne W, Turek-Herman J, Pagano PJ, St Croix CM, Sondheimer N, Yatsunyk LA, Johnson FB, Kaufman BA.

Sci Rep. 2019 Apr 3;9(1):5605. doi: 10.1038/s41598-019-41464-y.

4.

Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence.

Sen P, Lan Y, Li CY, Sidoli S, Donahue G, Dou Z, Frederick B, Chen Q, Luense LJ, Garcia BA, Dang W, Johnson FB, Adams PD, Schultz DC, Berger SL.

Mol Cell. 2019 Feb 21;73(4):684-698.e8. doi: 10.1016/j.molcel.2019.01.021. Epub 2019 Feb 14.

PMID:
30773298
5.

hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction.

Guha M, Srinivasan S, Johnson FB, Ruthel G, Guja K, Garcia-Diaz M, Kaufman BA, Glineburg MR, Fang J, Nakagawa H, Basha J, Kundu T, Avadhani NG.

PLoS One. 2018 Nov 14;13(11):e0206897. doi: 10.1371/journal.pone.0206897. eCollection 2018.

6.

Computational assessment of miRNA binding to low and high expression HLA-DPB1 allelic sequences.

Shieh M, Chitnis N, Clark P, Johnson FB, Kamoun M, Monos D.

Hum Immunol. 2019 Jan;80(1):53-61. doi: 10.1016/j.humimm.2018.09.002. Epub 2018 Sep 15. Review.

PMID:
30227197
7.

Understanding the evolving phenotype of vascular complications in telomere biology disorders.

Higgs C, Crow YJ, Adams DM, Chang E, Hayes D Jr, Herbig U, Huang JN, Himes R, Jajoo K, Johnson FB, Reynolds SD, Yonekawa Y, Armanios M, Boulad F, DiNardo CD, Dufour C, Goldman FD, Khan S, Kratz C, Myers KC, Raghu G, Alter BP, Aubert G, Bhala S, Cowen EW, Dror Y, El-Youssef M, Friedman B, Giri N, Helms Guba L, Khincha PP, Lin TF, Longhurst H, McReynolds LJ, Nelson A, Olson T, Pariser A, Perona R, Sasa G, Schratz K, Simonetto DA, Townsley D, Walsh M, Stevens K, Agarwal S, Bertuch AA, Savage SA; Clinical Care Consortium for Telomere-associated Ailments (CCCTAA).

Angiogenesis. 2019 Feb;22(1):95-102. doi: 10.1007/s10456-018-9640-7. Epub 2018 Aug 25.

PMID:
30168024
8.

A regulatory loop connecting WNT signaling and telomere capping: possible therapeutic implications for dyskeratosis congenita.

Fernandez RJ 3rd, Johnson FB.

Ann N Y Acad Sci. 2018 Apr;1418(1):56-68. doi: 10.1111/nyas.13692. Review.

PMID:
29722029
9.

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.

Fraietta JA, Lacey SF, Orlando EJ, Pruteanu-Malinici I, Gohil M, Lundh S, Boesteanu AC, Wang Y, O'Connor RS, Hwang WT, Pequignot E, Ambrose DE, Zhang C, Wilcox N, Bedoya F, Dorfmeier C, Chen F, Tian L, Parakandi H, Gupta M, Young RM, Johnson FB, Kulikovskaya I, Liu L, Xu J, Kassim SH, Davis MM, Levine BL, Frey NV, Siegel DL, Huang AC, Wherry EJ, Bitter H, Brogdon JL, Porter DL, June CH, Melenhorst JJ.

Nat Med. 2018 May;24(5):563-571. doi: 10.1038/s41591-018-0010-1. Epub 2018 Apr 30.

10.

TERRA and the histone methyltransferase Dot1 cooperate to regulate senescence in budding yeast.

Wanat JJ, Logsdon GA, Driskill JH, Deng Z, Lieberman PM, Johnson FB.

PLoS One. 2018 Apr 12;13(4):e0195698. doi: 10.1371/journal.pone.0195698. eCollection 2018.

11.

Epigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and Telomeres.

Song S, Johnson FB.

Genes (Basel). 2018 Apr 9;9(4). pii: E201. doi: 10.3390/genes9040201. Review.

12.

Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.

Nativio R, Donahue G, Berson A, Lan Y, Amlie-Wolf A, Tuzer F, Toledo JB, Gosai SJ, Gregory BD, Torres C, Trojanowski JQ, Wang LS, Johnson FB, Bonini NM, Berger SL.

Nat Neurosci. 2018 Jul;21(7):1018. doi: 10.1038/s41593-018-0124-2.

PMID:
29556027
13.

Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.

Nativio R, Donahue G, Berson A, Lan Y, Amlie-Wolf A, Tuzer F, Toledo JB, Gosai SJ, Gregory BD, Torres C, Trojanowski JQ, Wang LS, Johnson FB, Bonini NM, Berger SL.

Nat Neurosci. 2018 Apr;21(4):497-505. doi: 10.1038/s41593-018-0101-9. Epub 2018 Mar 5. Erratum in: Nat Neurosci. 2018 Mar 19;:.

14.

Novel and Haplotype Specific MicroRNAs Encoded by the Major Histocompatibility Complex.

Clark PM, Chitnis N, Shieh M, Kamoun M, Johnson FB, Monos D.

Sci Rep. 2018 Mar 1;8(1):3832. doi: 10.1038/s41598-018-19427-6.

15.

Potential Roles for G-Quadruplexes in Mitochondria.

Falabella M, Fernandez RJ, Johnson FB, Kaufman BA.

Curr Med Chem. 2019;26(16):2918-2932. doi: 10.2174/0929867325666180228165527. Review.

PMID:
29493440
16.

TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling.

Berson A, Sartoris A, Nativio R, Van Deerlin V, Toledo JB, Porta S, Liu S, Chung CY, Garcia BA, Lee VM, Trojanowski JQ, Johnson FB, Berger SL, Bonini NM.

Curr Biol. 2017 Dec 4;27(23):3579-3590.e6. doi: 10.1016/j.cub.2017.10.024. Epub 2017 Nov 16.

17.

Single Stem Cell Imaging and Analysis Reveals Telomere Length Differences in Diseased Human and Mouse Skeletal Muscles.

Tichy ED, Sidibe DK, Tierney MT, Stec MJ, Sharifi-Sanjani M, Hosalkar H, Mubarak S, Johnson FB, Sacco A, Mourkioti F.

Stem Cell Reports. 2017 Oct 10;9(4):1328-1341. doi: 10.1016/j.stemcr.2017.08.003. Epub 2017 Sep 7.

18.

Modeling Esophagitis Using Human Three-Dimensional Organotypic Culture System.

Laczkó D, Wang F, Johnson FB, Jhala N, Rosztóczy A, Ginsberg GG, Falk GW, Rustgi AK, Lynch JP.

Am J Pathol. 2017 Aug;187(8):1787-1799. doi: 10.1016/j.ajpath.2017.04.013. Epub 2017 Jun 13.

19.

Detection of G-quadruplex DNA in mammalian cells.

Henderson A, Wu Y, Huang YC, Chavez EA, Platt J, Johnson FB, Brosh RM Jr, Sen D, Lansdorp PM.

Nucleic Acids Res. 2017 Jun 2;45(10):6252. doi: 10.1093/nar/gkx300. No abstract available.

20.

Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche.

Yang TB, Chen Q, Deng JT, Jagannathan G, Tobias JW, Schultz DC, Wang S, Lengner CJ, Rustgi AK, Lynch JP, Johnson FB.

Nat Commun. 2017 Mar 17;8:14766. doi: 10.1038/ncomms14766.

21.

HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.

Guha M, Srinivasan S, Guja K, Mejia E, Garcia-Diaz M, Johnson FB, Ruthel G, Kaufman BA, Rappaport EF, Glineburg MR, Fang JK, Klein-Szanto AJ, Klein Szanto A, Nakagawa H, Basha J, Kundu T, Avadhani NG.

Cell Discov. 2016 Dec 6;2:16045. eCollection 2016. Erratum in: Cell Discov. 2019 May 14;5:28. Klein Szanto A [corrected to Klein-Szanto AJ].

22.

HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci.

Aird KM, Iwasaki O, Kossenkov AV, Tanizawa H, Fatkhutdinov N, Bitler BG, Le L, Alicea G, Yang TL, Johnson FB, Noma KI, Zhang R.

J Cell Biol. 2016 Nov 7;215(3):325-334. Epub 2016 Oct 31.

23.

Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence.

Crowe EP, Tuzer F, Gregory BD, Donahue G, Gosai SJ, Cohen J, Leung YY, Yetkin E, Nativio R, Wang LS, Sell C, Bonini NM, Berger SL, Johnson FB, Torres C.

Front Aging Neurosci. 2016 Aug 31;8:208. doi: 10.3389/fnagi.2016.00208. eCollection 2016.

24.

Enhancing a Wnt-Telomere Feedback Loop Restores Intestinal Stem Cell Function in a Human Organotypic Model of Dyskeratosis Congenita.

Woo DH, Chen Q, Yang TL, Glineburg MR, Hoge C, Leu NA, Johnson FB, Lengner CJ.

Cell Stem Cell. 2016 Sep 1;19(3):397-405. doi: 10.1016/j.stem.2016.05.024. Epub 2016 Aug 18.

25.

Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation.

McCullough CE, Song S, Shin MH, Johnson FB, Marmorstein R.

J Biol Chem. 2016 Aug 26;291(35):18190-8. doi: 10.1074/jbc.M116.736264. Epub 2016 Jul 5.

26.

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.

Katlinskaya YV, Katlinski KV, Lasri A, Li N, Beiting DP, Durham AC, Yang T, Pikarsky E, Lengner CJ, Johnson FB, Ben-Neriah Y, Fuchs SY.

Mol Cell Biol. 2016 Jan 25;36(7):1124-35. doi: 10.1128/MCB.00988-15.

27.

Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.

Aumailley L, Garand C, Dubois MJ, Johnson FB, Marette A, Lebel M.

PLoS One. 2015 Oct 8;10(10):e0140292. doi: 10.1371/journal.pone.0140292. eCollection 2015.

28.

DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.

Yu Q, Katlinskaya YV, Carbone CJ, Zhao B, Katlinski KV, Zheng H, Guha M, Li N, Chen Q, Yang T, Lengner CJ, Greenberg RA, Johnson FB, Fuchs SY.

Cell Rep. 2015 May 5;11(5):785-797. doi: 10.1016/j.celrep.2015.03.069. Epub 2015 Apr 23.

29.

Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells.

Frigault MJ, Lee J, Basil MC, Carpenito C, Motohashi S, Scholler J, Kawalekar OU, Guedan S, McGettigan SE, Posey AD Jr, Ang S, Cooper LJ, Platt JM, Johnson FB, Paulos CM, Zhao Y, Kalos M, Milone MC, June CH.

Cancer Immunol Res. 2015 Apr;3(4):356-67. doi: 10.1158/2326-6066.CIR-14-0186. Epub 2015 Jan 19.

30.

Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints.

Dong DW, Pereira F, Barrett SP, Kolesar JE, Cao K, Damas J, Yatsunyk LA, Johnson FB, Kaufman BA.

BMC Genomics. 2014 Aug 13;15:677. doi: 10.1186/1471-2164-15-677.

31.

A nested case-controlled comparison of telomere length and psychological functioning in breast cancer survivors with and without insomnia symptoms.

Garland SN, Palmer C, Donelson M, Gehrman P, Johnson FB, Mao JJ.

Rejuvenation Res. 2014 Oct;17(5):453-7. doi: 10.1089/rej.2014.1586.

32.

Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cells.

Johnson JE, Johnson FB.

PLoS One. 2014 May 15;9(5):e97729. doi: 10.1371/journal.pone.0097729. eCollection 2014.

33.

Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.

Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, Kennedy BK, Kaeberlein M, Berger SL.

Cell Metab. 2014 Jun 3;19(6):952-66. doi: 10.1016/j.cmet.2014.04.004. Epub 2014 May 8.

34.

Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A.

Kolocouris A, Tzitzoglaki C, Johnson FB, Zell R, Wright AK, Cross TA, Tietjen I, Fedida D, Busath DD.

J Med Chem. 2014 Jun 12;57(11):4629-39. doi: 10.1021/jm500598u. Epub 2014 May 15.

35.

Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.

Brennan TA, Egan KP, Lindborg CM, Chen Q, Sweetwyne MT, Hankenson KD, Xie SX, Johnson FB, Pignolo RJ.

Dis Model Mech. 2014 May;7(5):583-92. doi: 10.1242/dmm.014928. Epub 2014 Mar 13.

36.

Detection of G-quadruplex DNA in mammalian cells.

Henderson A, Wu Y, Huang YC, Chavez EA, Platt J, Johnson FB, Brosh RM Jr, Sen D, Lansdorp PM.

Nucleic Acids Res. 2014 Jan;42(2):860-9. doi: 10.1093/nar/gkt957. Epub 2013 Oct 24.

37.

Resolution by unassisted Top3 points to template switch recombination intermediates during DNA replication.

Glineburg MR, Chavez A, Agrawal V, Brill SJ, Johnson FB.

J Biol Chem. 2013 Nov 15;288(46):33193-204. doi: 10.1074/jbc.M113.496133. Epub 2013 Oct 7.

38.

Analysis of nonlinear gene expression progression reveals extensive pathway and age-specific transitions in aging human brains.

Cao K, Ryvkin P, Hwang YC, Johnson FB, Wang LS.

PLoS One. 2013 Oct 3;8(10):e74578. doi: 10.1371/journal.pone.0074578. eCollection 2013.

39.

R-Spondin 1 promotes vibration-induced bone formation in mouse models of osteoporosis.

Wang H, Brennan TA, Russell E, Kim JH, Egan KP, Chen Q, Israelite C, Schultz DC, Johnson FB, Pignolo RJ.

J Mol Med (Berl). 2013 Dec;91(12):1421-9. doi: 10.1007/s00109-013-1068-3. Epub 2013 Aug 24.

40.

Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence.

Platt JM, Ryvkin P, Wanat JJ, Donahue G, Ricketts MD, Barrett SP, Waters HJ, Song S, Chavez A, Abdallah KO, Master SR, Wang LS, Johnson FB.

Genes Dev. 2013 Jun 15;27(12):1406-20. doi: 10.1101/gad.218776.113. Epub 2013 Jun 11.

41.

Long-term functional engraftment of mesenchymal progenitor cells in a mouse model of accelerated aging.

Singh L, Brennan TA, Kim JH, Egan KP, McMillan EA, Chen Q, Hankenson KD, Zhang Y, Emerson SG, Johnson FB, Pignolo RJ.

Stem Cells. 2013 Mar;31(3):607-11. doi: 10.1002/stem.1294.

42.

Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance.

Mason M, Wanat JJ, Harper S, Schultz DC, Speicher DW, Johnson FB, Skordalakes E.

Structure. 2013 Jan 8;21(1):109-120. doi: 10.1016/j.str.2012.10.012. Epub 2012 Nov 21.

43.

Astrocyte senescence as a component of Alzheimer's disease.

Bhat R, Crowe EP, Bitto A, Moh M, Katsetos CD, Garcia FU, Johnson FB, Trojanowski JQ, Sell C, Torres C.

PLoS One. 2012;7(9):e45069. doi: 10.1371/journal.pone.0045069. Epub 2012 Sep 12.

44.

G-ruption: the third international meeting on G-quadruplex and G-assembly.

Yatsunyk LA, Bryan TM, Johnson FB.

Biochimie. 2012 Dec;94(12):2475-83. doi: 10.1016/j.biochi.2012.09.002. Epub 2012 Sep 10.

45.

Computational detection and analysis of sequences with duplex-derived interstrand G-quadruplex forming potential.

Cao K, Ryvkin P, Johnson FB.

Methods. 2012 May;57(1):3-10. doi: 10.1016/j.ymeth.2012.05.002. Epub 2012 May 29.

46.

Telomere stability and carcinogenesis: an off-again, on-again relationship.

Wanat JJ, Johnson FB.

J Clin Invest. 2012 Jun;122(6):1962-5. doi: 10.1172/JCI63979. Epub 2012 May 24.

47.

Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging.

Wang H, Chen Q, Lee SH, Choi Y, Johnson FB, Pignolo RJ.

Aging Cell. 2012 Aug;11(4):704-13. doi: 10.1111/j.1474-9726.2012.00838.x. Epub 2012 Jun 11.

48.

MYST protein acetyltransferase activity requires active site lysine autoacetylation.

Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, Thibault P, Verreault A, Johnson FB, Berger SL, Sternglanz R, McMahon SB, Côté J, Marmorstein R.

EMBO J. 2012 Jan 4;31(1):58-70. doi: 10.1038/emboj.2011.382. Epub 2011 Oct 21.

49.

Characterization of herpes simplex virus clinical isolate Y3369 as a glycoprotein G variant and its bearing on virus typing.

Clark DN, Poole BD, Hammond DV, Hedman TJ, Catts DS, Stewart A, Johnson FB.

Virol J. 2011 Jun 9;8:290. doi: 10.1186/1743-422X-8-290.

50.

PinX1 the tail on the chromosome.

Johnson FB.

J Clin Invest. 2011 Apr;121(4):1242-4. doi: 10.1172/JCI57024. Epub 2011 Mar 23.

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