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Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis.

Hill K, Walker SN, Salminen A, Chung HL, Li X, Ezzat B, Miller JJ, DesOrmeaux JS, Zhang J, Hayden A, Burgin T, Piraino L, May MN, Gaborski TR, Roussie JA, Taylor J, DiVincenti L Jr, Shestopalov AA, McGrath JL, Johnson DG.

Adv Healthc Mater. 2020 Jan 15:e1900750. doi: 10.1002/adhm.201900750. [Epub ahead of print]


E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair.

Manickavinayaham S, Vélez-Cruz R, Biswas AK, Bedford E, Klein BJ, Kutateladze TG, Liu B, Bedford MT, Johnson DG.

Nat Commun. 2019 Oct 30;10(1):4951. doi: 10.1038/s41467-019-12861-8.


Protein Separation and Hemocompatibility of Nitride Membranes in Microfluidic Filtration Systems.

Salminen A, Hill K, Henry Chung L, James McGrath L, Johnson DG.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:5814-5817. doi: 10.1109/EMBC.2018.8513538.


Contrasting effects of an Mdm2 functional polymorphism on tumor phenotypes.

Ortiz GJ, Li Y, Post SM, Pant V, Xiong S, Larsson CA, El-Naggar AK, Johnson DG, Lozano G.

Oncogene. 2018 Jan 18;37(3):332-340. doi: 10.1038/onc.2017.344. Epub 2017 Sep 18.


The Retinoblastoma (RB) Tumor Suppressor: Pushing Back against Genome Instability on Multiple Fronts.

Vélez-Cruz R, Johnson DG.

Int J Mol Sci. 2017 Aug 16;18(8). pii: E1776. doi: 10.3390/ijms18081776. Review.


The p53 R72P polymorphism does not affect the physiological response to ionizing radiation in a mouse model.

Domínguez ER, Orona J, Lin K, Pérez CJ, Benavides F, Kusewitt DF, Johnson DG.

Cell Cycle. 2017 Jun 18;16(12):1153-1163. doi: 10.1080/15384101.2017.1312234. Epub 2017 Jun 8.


Nanoporous membrane robustness / stability in small form factor microfluidic filtration system.

Johnson DG, Pan S, Hayden A, McGrath JL.

Conf Proc IEEE Eng Med Biol Soc. 2016 Aug;2016:1955-1958. doi: 10.1109/EMBC.2016.7591106.


RB localizes to DNA double-strand breaks and promotes DNA end resection and homologous recombination through the recruitment of BRG1.

Vélez-Cruz R, Manickavinayaham S, Biswas AK, Clary RW, Premkumar T, Cole F, Johnson DG.

Genes Dev. 2016 Nov 15;30(22):2500-2512.


TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1.

Hossain MB, Shifat R, Johnson DG, Bedford MT, Gabrusiewicz KR, Cortes-Santiago N, Luo X, Lu Z, Ezhilarasan R, Sulman EP, Jiang H, Li SS, Lang FF, Tyler J, Hung MC, Fueyo J, Gomez-Manzano C.

Sci Adv. 2016 Apr 1;2(4):e1501290. eCollection 2016 Apr.


Towards an Implantable, Low Flow Micropump That Uses No Power in the Blocked-Flow State.

Johnson DG, Borkholder DA.

Micromachines (Basel). 2016 Jun 1;7(6). pii: E99. doi: 10.3390/mi7060099.


Structure of Amido Pyridinium Betaines: Persistent Intermolecular C-H⋅⋅⋅N Hydrogen Bonding in Solution.

Thatcher RJ, Johnson DG, Slattery JM, Douthwaite RE.

Chemistry. 2016 Mar 1;22(10):3414-3421. doi: 10.1002/chem.201503884. Epub 2016 Jan 28.


Chirality Transfer in Gold(I)-Catalysed Direct Allylic Etherifications of Unactivated Alcohols: Experimental and Computational Study.

Barker G, Johnson DG, Young PC, Macgregor SA, Lee AL.

Chemistry. 2015 Sep 21;21(39):13748-57. doi: 10.1002/chem.201501607. Epub 2015 Aug 6.


Gold-Catalyzed Proto- and Deuterodeboronation.

Barker G, Webster S, Johnson DG, Curley R, Andrews M, Young PC, Macgregor SA, Lee AL.

J Org Chem. 2015 Oct 16;80(20):9807-16. doi: 10.1021/acs.joc.5b01041. Epub 2015 Jul 8.


Far-infrared spectroscopy of the troposphere: calibration with a cold background.

Latvakoski H, Mlynczak MG, Cageao RP, Johnson DG, Kratz DP.

Appl Opt. 2014 Aug 20;53(24):5425-33. doi: 10.1364/AO.53.005425.


Palladium-catalyzed direct C-H functionalization of benzoquinone.

Walker SE, Jordan-Hore JA, Johnson DG, Macgregor SA, Lee AL.

Angew Chem Int Ed Engl. 2014 Dec 8;53(50):13876-9. doi: 10.1002/anie.201408054. Epub 2014 Oct 10.


Gold(I)-catalysed direct thioetherifications using allylic alcohols: an experimental and computational study.

Herkert L, Green SL, Barker G, Johnson DG, Young PC, Macgregor SA, Lee AL.

Chemistry. 2014 Sep 1;20(36):11540-8. doi: 10.1002/chem.201403293. Epub 2014 Jul 30.


E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis.

Biswas AK, Mitchell DL, Johnson DG.

Cancer Res. 2014 Jun 15;74(12):3369-77. doi: 10.1158/0008-5472.CAN-13-3216. Epub 2014 Apr 16.


Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif.

Guan X, Liu Z, Wang L, Johnson DG, Wei Q.

Biochem Biophys Res Commun. 2014 Jan 24;443(4):1239-44. doi: 10.1016/j.bbrc.2013.12.124. Epub 2014 Jan 3.


Ultrathin silicon membranes for wearable dialysis.

Johnson DG, Khire TS, Lyubarskaya YL, Smith KJ, Desormeaux JP, Taylor JG, Gaborski TR, Shestopalov AA, Striemer CC, McGrath JL.

Adv Chronic Kidney Dis. 2013 Nov;20(6):508-15. doi: 10.1053/j.ackd.2013.08.001. Review.


Acute onset of lower limb weakness, sphincter dysfunction and sensory disturbance in an older woman.

Lamprell L, Johnson DG.

Med J Aust. 2013 Sep 16;199(6):427. No abstract available.


Slug expression in mouse skin and skin tumors is not regulated by p53.

Perez CJ, Rundhaug JE, Johnson DG, Oberyszyn TM, Tober KL, Kusewitt DF.

J Invest Dermatol. 2014 Feb;134(2):566-568. doi: 10.1038/jid.2013.363. Epub 2013 Sep 5. No abstract available.


Modeling gene-environment interactions in oral cavity and esophageal cancers demonstrates a role for the p53 R72P polymorphism in modulating susceptibility.

Sarkar J, Dominguez E, Li G, Kusewitt DF, Johnson DG.

Mol Carcinog. 2014 Aug;53(8):648-58. doi: 10.1002/mc.22019. Epub 2013 Mar 8.


Chromatin: receiver and quarterback for cellular signals.

Johnson DG, Dent SY.

Cell. 2013 Feb 14;152(4):685-9. doi: 10.1016/j.cell.2013.01.017. Epub 2013 Jan 31. Review.


Far-infrared spectroscopy of the troposphere: instrument description and calibration performance.

Latvakoski H, Mlynczak MG, Johnson DG, Cageao RP, Kratz DP, Johnson K.

Appl Opt. 2013 Jan 10;52(2):264-73. doi: 10.1364/AO.52.000264.


Ruthenium-mediated C-H functionalization of pyridine: the role of vinylidene and pyridylidene ligands.

Johnson DG, Lynam JM, Mistry NS, Slattery JM, Thatcher RJ, Whitwood AC.

J Am Chem Soc. 2013 Feb 13;135(6):2222-34. doi: 10.1021/ja3097256. Epub 2013 Jan 31.


E2F1 and p53 transcription factors as accessory factors for nucleotide excision repair.

Vélez-Cruz R, Johnson DG.

Int J Mol Sci. 2012 Oct 19;13(10):13554-68. doi: 10.3390/ijms131013554. Review.


Absolute linearity measurement of photodetectors using sinusoidal modulated radiation.

Refaat TF, Johnson DG.

Appl Opt. 2012 Jul 1;51(19):4420-9. doi: 10.1364/AO.51.004420.


Short communication: Jersey × Holstein crossbreds compared with pure Holsteins for body weight, body condition score, fertility, and survival during the first three lactations.

Heins BJ, Hansen LB, Hazel AR, Seykora AJ, Johnson DG, Linn JG.

J Dairy Sci. 2012 Jul;95(7):4130-5. doi: 10.3168/jds.2011-5077.


Charged behaviour from neutral ligands: synthesis and properties of N-heterocyclic pseudo-amides.

Thatcher RJ, Johnson DG, Slattery JM, Douthwaite RE.

Chemistry. 2012 Apr 2;18(14):4329-36. doi: 10.1002/chem.201103319. Epub 2012 Feb 29.


Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck.

Lu M, Liu Z, Yu H, Wang LE, Li G, Sturgis EM, Johnson DG, Wei Q.

Mol Carcinog. 2012 Oct;51 Suppl 1:E132-41. doi: 10.1002/mc.21882. Epub 2012 Feb 17.


Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage.

Biswas AK, Johnson DG.

Cancer Res. 2012 Jan 1;72(1):13-7. doi: 10.1158/0008-5472.CAN-11-2196. Epub 2011 Dec 16. Review.


Repression of androgen receptor transcription through the E2F1/DNMT1 axis.

Valdez CD, Davis JN, Odeh HM, Layfield TL, Cousineau CS, Berton TR, Johnson DG, Wojno KJ, Day ML.

PLoS One. 2011;6(9):e25187. doi: 10.1371/journal.pone.0025187. Epub 2011 Sep 26.


Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neck.

Yu H, Huang YJ, Liu Z, Wang LE, Li G, Sturgis EM, Johnson DG, Wei Q.

Mol Carcinog. 2011 Sep;50(9):697-706. doi: 10.1002/mc.20806. Epub 2011 Jun 7.


E2F1 promotes the recruitment of DNA repair factors to sites of DNA double-strand breaks.

Chen J, Zhu F, Weaks RL, Biswas AK, Guo R, Li Y, Johnson DG.

Cell Cycle. 2011 Apr 15;10(8):1287-94. doi: 10.4161/cc.10.8.15341.


Short communication: Jersey × Holstein crossbreds compared with pure Holsteins for production, mastitis, and body measurements during the first 3 lactations.

Heins BJ, Hansen LB, Seykora AJ, Hazel AR, Johnson DG, Linn JG.

J Dairy Sci. 2011 Jan;94(1):501-6. doi: 10.3168/jds.2010-3232.


In-plane biocompatible microfluidic interconnects for implantable microsystems.

Johnson DG, Frisina RD, Borkholder DA.

IEEE Trans Biomed Eng. 2011 Apr;58(4):943-8. doi: 10.1109/TBME.2010.2098031. Epub 2010 Dec 10.


Reflux esophageal stricture--a review of 30 years' experience in children.

Pearson EG, Downey EC, Barnhart DC, Scaife ER, Rollins MD, Black RE, Matlak ME, Johnson DG, Meyers RL.

J Pediatr Surg. 2010 Dec;45(12):2356-60. doi: 10.1016/j.jpedsurg.2010.08.033.


Implantable micropump technologies for murine intracochlear infusions.

Johnson DG, Waldron MJ, Frisina RD, Borkholder DA.

Conf Proc IEEE Eng Med Biol Soc. 2010;2010:6441-4. doi: 10.1109/IEMBS.2010.5627335.


GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage.

Guo R, Chen J, Mitchell DL, Johnson DG.

Nucleic Acids Res. 2011 Mar;39(4):1390-7. doi: 10.1093/nar/gkq983. Epub 2010 Oct 23.


Insights into the intramolecular acetate-mediated formation of ruthenium vinylidene complexes: a ligand-assisted proton shuttle (LAPS) mechanism.

Johnson DG, Lynam JM, Slattery JM, Welby CE.

Dalton Trans. 2010 Nov 21;39(43):10432-41. doi: 10.1039/c0dt00431f. Epub 2010 Oct 12.


INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway.

Jiang Y, Wang X, Bao S, Guo R, Johnson DG, Shen X, Li L.

Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17274-9. doi: 10.1073/pnas.1008388107. Epub 2010 Sep 20.


The role of ethics in science and engineering.

Johnson DG.

Trends Biotechnol. 2010 Dec;28(12):589-90. doi: 10.1016/j.tibtech.2010.08.003.


A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development.

Post SM, Quintás-Cardama A, Pant V, Iwakuma T, Hamir A, Jackson JG, Maccio DR, Bond GL, Johnson DG, Levine AJ, Lozano G.

Cancer Cell. 2010 Sep 14;18(3):220-30. doi: 10.1016/j.ccr.2010.07.010.


The RB-E2F1 pathway regulates autophagy.

Jiang H, Martin V, Gomez-Manzano C, Johnson DG, Alonso M, White E, Xu J, McDonnell TJ, Shinojima N, Fueyo J.

Cancer Res. 2010 Oct 15;70(20):7882-93. doi: 10.1158/0008-5472.CAN-10-1604. Epub 2010 Aug 31.


Clinical variables as prognostic tools in pediatric-onset ulcerative colitis: a retrospective cohort study.

Moore JC, Thompson K, Lafleur B, Book LS, Jackson WD, O'Gorman MA, Black RE, Downey E Jr, Johnson DG, Matlak ME, Meyers RL, Scaife E, Guthery SL.

Inflamm Bowel Dis. 2011 Jan;17(1):15-21. doi: 10.1002/ibd.21393.


Mouse models for the p53 R72P polymorphism mimic human phenotypes.

Zhu F, Dollé ME, Berton TR, Kuiper RV, Capps C, Espejo A, McArthur MJ, Bedford MT, van Steeg H, de Vries A, Johnson DG.

Cancer Res. 2010 Jul 15;70(14):5851-9. doi: 10.1158/0008-5472.CAN-09-4646. Epub 2010 Jun 29.


E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair.

Guo R, Chen J, Zhu F, Biswas AK, Berton TR, Mitchell DL, Johnson DG.

J Biol Chem. 2010 Jun 18;285(25):19308-15. doi: 10.1074/jbc.M110.121939. Epub 2010 Apr 22.


Birth traits of pure Holstein calves versus Montbeliarde-sired crossbred calves.

Heins BJ, Hansen LB, Hazel AR, Seykora AJ, Johnson DG, Linn JG.

J Dairy Sci. 2010 May;93(5):2293-9. doi: 10.3168/jds.2009-2911.


E2F2 suppresses Myc-induced proliferation and tumorigenesis.

Pusapati RV, Weaks RL, Rounbehler RJ, McArthur MJ, Johnson DG.

Mol Carcinog. 2010 Feb;49(2):152-6. doi: 10.1002/mc.20584.


Evaluation of Gram-positive rod surveillance for early anthrax detection.

Mlynarski D, Rabatsky-Ehr T, Petit S, Purviance K, Mshar PA, Begier EM, Johnson DG, Hadler JL; Connecticut Bioterrorism Field Epidemiology Response Team.

Epidemiol Infect. 2009 Nov;137(11):1623-30. doi: 10.1017/S0950268809002581. Epub 2009 Apr 27.


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