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Items: 1 to 50 of 183

1.

The gut microbiome as a driver of individual variation in cognition and functional behaviour.

Davidson GL, Cooke AC, Johnson CN, Quinn JL.

Philos Trans R Soc Lond B Biol Sci. 2018 Sep 26;373(1756). pii: 20170286. doi: 10.1098/rstb.2017.0286. Review.

PMID:
30104431
2.

A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660).

Johnson CN, Ahn JS, Buck IM, Chiarparin E, Day JEH, Hopkins A, Howard S, Lewis EJ, Martins V, Millemaggi A, Munck JM, Page LW, Peakman T, Reader M, Rich SJ, Saxty G, Smyth T, Thompson NT, Ward GA, Williams PA, Wilsher NE, Chessari G.

J Med Chem. 2018 Aug 9. doi: 10.1021/acs.jmedchem.8b00900. [Epub ahead of print]

PMID:
30091600
3.

Modeling underwater noise propagation from marine hydrokinetic power devices through a time-domain, velocity-pressure solution.

Hafla E, Johnson E, Johnson CN, Preston L, Aldridge D, Roberts JD.

J Acoust Soc Am. 2018 Jun;143(6):3242. doi: 10.1121/1.5039839.

PMID:
29960489
4.

Residual setup errors towards the heart after image guidance linked with poorer survival in lung cancer patients: do we need stricter IGRT protocols?

Johnson CN, Price GJ, Faivre-Finn C, Aznar MC, van Herk M.

Int J Radiat Oncol Biol Phys. 2018 Jun 1. pii: S0360-3016(18)30904-0. doi: 10.1016/j.ijrobp.2018.05.052. [Epub ahead of print]

PMID:
29908945
5.

Liposomal bupivacaine reduces opioid consumption and length of stay in patients undergoing primary total hip arthroplasty.

VanWagner MJ, Krebs NM, Corser W, Johnson CN.

Hip Int. 2018 May 1:1120700018778240. doi: 10.1177/1120700018778240. [Epub ahead of print]

PMID:
29808726
6.

Charles Darwin, Richard Owen, and Natural Selection: A Question of Priority.

Johnson CN.

J Hist Biol. 2018 May 3. doi: 10.1007/s10739-018-9514-2. [Epub ahead of print]

PMID:
29725900
7.

ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth.

Ward GA, Lewis EJ, Ahn JS, Johnson CN, Lyons JF, Martins V, Munck JM, Rich SJ, Smyth T, Thompson NT, Williams PA, Wilsher NE, Wallis NG, Chessari G.

Mol Cancer Ther. 2018 Jul;17(7):1381-1391. doi: 10.1158/1535-7163.MCT-17-0848. Epub 2018 Apr 25.

PMID:
29695633
8.

Multi-wavelength analytical ultracentrifugation of human serum albumin complexed with porphyrin.

Johnson CN, Gorbet GE, Ramsower H, Urquidi J, Brancaleon L, Demeler B.

Eur Biophys J. 2018 Apr 19. doi: 10.1007/s00249-018-1301-7. [Epub ahead of print]

PMID:
29675648
9.

A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel.

Johnson CN, Potet F, Thompson MK, Kroncke BM, Glazer AM, Voehler MW, Knollmann BC, George AL Jr, Chazin WJ.

Structure. 2018 May 1;26(5):683-694.e3. doi: 10.1016/j.str.2018.03.005. Epub 2018 Apr 5.

PMID:
29606593
10.

MRI Identification of the Osseous Extent of Pediatric Bone Sarcomas.

Thompson MJ, Shapton JC, Punt SE, Johnson CN, Conrad EU 3rd.

Clin Orthop Relat Res. 2018 Mar;476(3):559-564. doi: 10.1007/s11999.0000000000000068.

PMID:
29529641
11.

Characterization of Pathogenic Vibrio parahaemolyticus from the Chesapeake Bay, Maryland.

Chen AJ, Hasan NA, Haley BJ, Taviani E, Tarnowski M, Brohawn K, Johnson CN, Colwell RR, Huq A.

Front Microbiol. 2017 Dec 15;8:2460. doi: 10.3389/fmicb.2017.02460. eCollection 2017.

12.

Exopolysaccharide production in Caulobacter crescentus: A resource allocation trade-off between protection and proliferation.

Herr KL, Carey AM, Heckman TI, Chávez JL, Johnson CN, Harvey E, Gamroth WA, Wulfing BS, Van Kessel RA, Marks ME.

PLoS One. 2018 Jan 2;13(1):e0190371. doi: 10.1371/journal.pone.0190371. eCollection 2018.

13.

Dietary partitioning of Australia's two marsupial hypercarnivores, the Tasmanian devil and the spotted-tailed quoll, across their shared distributional range.

Andersen GE, Johnson CN, Barmuta LA, Jones ME.

PLoS One. 2017 Nov 27;12(11):e0188529. doi: 10.1371/journal.pone.0188529. eCollection 2017.

14.

Prey use by dingoes in a contested landscape: Ecosystem service provider or biodiversity threat?

Morrant DS, Wurster CM, Johnson CN, Butler JRA, Congdon BC.

Ecol Evol. 2017 Sep 21;7(21):8927-8935. doi: 10.1002/ece3.3345. eCollection 2017 Nov.

15.

Fragment-to-Lead Medicinal Chemistry Publications in 2016.

Johnson CN, Erlanson DA, Jahnke W, Mortenson PN, Rees DC.

J Med Chem. 2018 Mar 8;61(5):1774-1784. doi: 10.1021/acs.jmedchem.7b01298. Epub 2017 Oct 31.

PMID:
29087197
16.

Ecological and evolutionary legacy of megafauna extinctions.

Galetti M, Moleón M, Jordano P, Pires MM, Guimarães PR Jr, Pape T, Nichols E, Hansen D, Olesen JM, Munk M, de Mattos JS, Schweiger AH, Owen-Smith N, Johnson CN, Marquis RJ, Svenning JC.

Biol Rev Camb Philos Soc. 2018 May;93(2):845-862. doi: 10.1111/brv.12374. Epub 2017 Oct 9.

PMID:
28990321
17.

Use of anthropogenic linear features by two medium-sized carnivores in reserved and agricultural landscapes.

Andersen GE, Johnson CN, Barmuta LA, Jones ME.

Sci Rep. 2017 Sep 14;7(1):11624. doi: 10.1038/s41598-017-11454-z.

18.

Results from a clinical trial evaluating the efficacy of real-time body surface visual feedback in reducing patient motion during lung cancer radiotherapy.

Price GJ, Faivre-Finn C, Stratford J, Chauhan S, Bewley M, Clarke L, Johnson CN, Moore CJ.

Acta Oncol. 2018 Feb;57(2):211-218. doi: 10.1080/0284186X.2017.1360511. Epub 2017 Aug 7.

PMID:
28780900
19.

The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.

Carson WF 4th, Cavassani KA, Soares EM, Hirai S, Kittan NA, Schaller MA, Scola MM, Joshi A, Matsukawa A, Aronoff DM, Johnson CN, Dou Y, Gallagher KA, Kunkel SL.

J Immunol. 2017 Sep 1;199(5):1865-1874. doi: 10.4049/jimmunol.1601272. Epub 2017 Jul 21.

PMID:
28733487
20.

Calmodulin Mutants Linked to Catecholaminergic Polymorphic Ventricular Tachycardia Fail to Inhibit Human RyR2 Channels.

Walweel K, Gomez-Hurtado N, Oo YW, Beard NA, Dos Remedios C, Johnson CN, Chazin WJ, van Helden DF, Knollmann BC, Laver DR.

J Am Coll Cardiol. 2017 Jul 4;70(1):115-117. doi: 10.1016/j.jacc.2017.04.055. No abstract available.

21.

The hookworm Ancylostoma ceylanicum: An emerging public health risk in Australian tropical rainforests and Indigenous communities.

Smout FA, Skerratt LF, Butler JRA, Johnson CN, Congdon BC, Thompson RCA.

One Health. 2017 Apr 26;3:66-69. doi: 10.1016/j.onehlt.2017.04.002. eCollection 2017 Jun.

22.

Top predators constrain mesopredator distributions.

Newsome TM, Greenville AC, Ćirović D, Dickman CR, Johnson CN, Krofel M, Letnic M, Ripple WJ, Ritchie EG, Stoyanov S, Wirsing AJ.

Nat Commun. 2017 May 23;8:15469. doi: 10.1038/ncomms15469.

23.

Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP).

Tamanini E, Buck IM, Chessari G, Chiarparin E, Day JEH, Frederickson M, Griffiths-Jones CM, Hearn K, Heightman TD, Iqbal A, Johnson CN, Lewis EJ, Martins V, Peakman T, Reader M, Rich SJ, Ward GA, Williams PA, Wilsher NE.

J Med Chem. 2017 Jun 8;60(11):4611-4625. doi: 10.1021/acs.jmedchem.6b01877. Epub 2017 May 24.

PMID:
28492317
24.

Biodiversity losses and conservation responses in the Anthropocene.

Johnson CN, Balmford A, Brook BW, Buettel JC, Galetti M, Guangchun L, Wilmshurst JM.

Science. 2017 Apr 21;356(6335):270-275. doi: 10.1126/science.aam9317. Review.

PMID:
28428393
25.

Communicating Science through a Novel Type of Journal.

Juarez MT, Kenet CM, Johnson CN.

CBE Life Sci Educ. 2017 Summer;16(2). pii: le2. doi: 10.1187/cbe.16-12-0345. No abstract available.

26.

Is God just a big person? Children's conceptions of God across cultures and religious traditions.

Nyhof MA, Johnson CN.

Br J Dev Psychol. 2017 Mar;35(1):60-75. doi: 10.1111/bjdp.12173.

PMID:
28220954
27.

Induction of p53 suppresses chronic myeloid leukemia.

Peterson LF, Lo MC, Liu Y, Giannola D, Mitrikeska E, Donato NJ, Johnson CN, Wang S, Mercer J, Talpaz M.

Leuk Lymphoma. 2017 Sep;58(9):1-14. doi: 10.1080/10428194.2016.1272682. Epub 2017 Jan 13.

PMID:
28084835
28.

Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras.

Lebraud H, Wright DJ, Johnson CN, Heightman TD.

ACS Cent Sci. 2016 Dec 28;2(12):927-934. doi: 10.1021/acscentsci.6b00280. Epub 2016 Dec 5.

29.

Livestock guardian dogs as surrogate top predators? How Maremma sheepdogs affect a wildlife community.

van Bommel L, Johnson CN.

Ecol Evol. 2016 Aug 30;6(18):6702-6711. eCollection 2016 Sep.

30.

Fragment-to-Lead Medicinal Chemistry Publications in 2015.

Johnson CN, Erlanson DA, Murray CW, Rees DC.

J Med Chem. 2017 Jan 12;60(1):89-99. doi: 10.1021/acs.jmedchem.6b01123. Epub 2016 Oct 14. Review.

PMID:
27739691
31.

Occupancy of the Invasive Feral Cat Varies with Habitat Complexity.

Hohnen R, Tuft K, McGregor HW, Legge S, Radford IJ, Johnson CN.

PLoS One. 2016 Sep 21;11(9):e0152520. doi: 10.1371/journal.pone.0152520. eCollection 2016.

32.

Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks.

Evelyn CR, Lisabeth EM, Wade SM, Haak AJ, Johnson CN, Lawlor ER, Neubig RR.

Microarrays (Basel). 2016 May 28;5(2). pii: E13. doi: 10.3390/microarrays5020013.

33.

Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks.

Gomez-Hurtado N, Boczek NJ, Kryshtal DO, Johnson CN, Sun J, Nitu FR, Cornea RL, Chazin WJ, Calvert ML, Tester DJ, Ackerman MJ, Knollmann BC.

Circ Arrhythm Electrophysiol. 2016 Aug;9(8). pii: e004161. doi: 10.1161/CIRCEP.116.004161.

34.

A comprehensive database of quality-rated fossil ages for Sahul's Quaternary vertebrates.

Rodríguez-Rey M, Herrando-Pérez S, Brook BW, Saltré F, Alroy J, Beeton N, Bird MI, Cooper A, Gillespie R, Jacobs Z, Johnson CN, Miller GH, Prideaux GJ, Roberts RG, Turney CS, Bradshaw CJ.

Sci Data. 2016 Jul 19;3:160053. doi: 10.1038/sdata.2016.53.

35.

Four-channel optically pumped atomic magnetometer for magnetoencephalography.

Colombo AP, Carter TR, Borna A, Jau YY, Johnson CN, Dagel AL, Schwindt PD.

Opt Express. 2016 Jul 11;24(14):15403-16. doi: 10.1364/OE.24.015403.

36.

Novel calmodulin mutations associated with congenital long QT syndrome affect calcium current in human cardiomyocytes.

Pipilas DC, Johnson CN, Webster G, Schlaepfer J, Fellmann F, Sekarski N, Wren LM, Ogorodnik KV, Chazin DM, Chazin WJ, Crotti L, Bhuiyan ZA, George AL Jr.

Heart Rhythm. 2016 Oct;13(10):2012-9. doi: 10.1016/j.hrthm.2016.06.038. Epub 2016 Jul 1.

37.

Preparing Tomorrow's Doctors to Care for Patients With Autism Spectrum Disorder.

Havercamp SM, Ratliff-Schaub K, Macho PN, Johnson CN, Bush KL, Souders HT.

Intellect Dev Disabil. 2016 Jun;54(3):202-16. doi: 10.1352/1934-9556-54.3.202.

PMID:
27268475
38.

Pyrodiversity is the coupling of biodiversity and fire regimes in food webs.

Bowman DM, Perry GL, Higgins SI, Johnson CN, Fuhlendorf SD, Murphy BP.

Philos Trans R Soc Lond B Biol Sci. 2016 Jun 5;371(1696). pii: 20150169. doi: 10.1098/rstb.2015.0169. Review.

39.

Spectrum and Prevalence of CALM1-, CALM2-, and CALM3-Encoded Calmodulin Variants in Long QT Syndrome and Functional Characterization of a Novel Long QT Syndrome-Associated Calmodulin Missense Variant, E141G.

Boczek NJ, Gomez-Hurtado N, Ye D, Calvert ML, Tester DJ, Kryshtal D, Hwang HS, Johnson CN, Chazin WJ, Loporcaro CG, Shah M, Papez AL, Lau YR, Kanter R, Knollmann BC, Ackerman MJ.

Circ Cardiovasc Genet. 2016 Apr;9(2):136-146. doi: 10.1161/CIRCGENETICS.115.001323. Epub 2016 Mar 11.

40.

Sarcoptes scabiei: The Mange Mite with Mighty Effects on the Common Wombat (Vombatus ursinus).

Simpson K, Johnson CN, Carver S.

PLoS One. 2016 Mar 4;11(3):e0149749. doi: 10.1371/journal.pone.0149749. eCollection 2016. Erratum in: PLoS One. 2016;11(4):e0153997.

41.

Extraterritorial hunting expeditions to intense fire scars by feral cats.

McGregor HW, Legge S, Jones ME, Johnson CN.

Sci Rep. 2016 Mar 2;6:22559. doi: 10.1038/srep22559.

42.

Resuscitation with Valproic Acid Alters Inflammatory Genes in a Porcine Model of Combined Traumatic Brain Injury and Hemorrhagic Shock.

Bambakidis T, Dekker SE, Sillesen M, Liu B, Johnson CN, Jin G, de Vries HE, Li Y, Alam HB.

J Neurotrauma. 2016 Aug 15;33(16):1514-21. doi: 10.1089/neu.2015.4163. Epub 2016 Apr 8.

43.

What caused extinction of the Pleistocene megafauna of Sahul?

Johnson CN, Alroy J, Beeton NJ, Bird MI, Brook BW, Cooper A, Gillespie R, Herrando-Pérez S, Jacobs Z, Miller GH, Prideaux GJ, Roberts RG, Rodríguez-Rey M, Saltré F, Turney CS, Bradshaw CJ.

Proc Biol Sci. 2016 Feb 10;283(1824). pii: 20152399. doi: 10.1098/rspb.2015.2399. Review.

44.

Climate change not to blame for late Quaternary megafauna extinctions in Australia.

Saltré F, Rodríguez-Rey M, Brook BW, Johnson CN, Turney CS, Alroy J, Cooper A, Beeton N, Bird MI, Fordham DA, Gillespie R, Herrando-Pérez S, Jacobs Z, Miller GH, Nogués-Bravo D, Prideaux GJ, Roberts RG, Bradshaw CJ.

Nat Commun. 2016 Jan 29;7:10511. doi: 10.1038/ncomms10511.

45.

Dingoes (Canis dingo Meyer, 1793) continue to be an important reservoir host of Dirofilaria immitis in low density housing areas in Australia.

Smout FA, Skerratt LF, Butler JR, Johnson CN, Congdon BC.

Vet Parasitol. 2016 Jan 15;215:6-10. doi: 10.1016/j.vetpar.2015.10.020. Epub 2015 Oct 27.

PMID:
26790730
46.

Combining paleo-data and modern exclosure experiments to assess the impact of megafauna extinctions on woody vegetation.

Bakker ES, Gill JL, Johnson CN, Vera FW, Sandom CJ, Asner GP, Svenning JC.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):847-55. doi: 10.1073/pnas.1502545112. Epub 2015 Oct 26. Review.

47.

MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells.

Beke L, Kig C, Linders JT, Boens S, Boeckx A, van Heerde E, Parade M, De Bondt A, Van den Wyngaert I, Bashir T, Ogata S, Meerpoel L, Van Eynde A, Johnson CN, Beullens M, Brehmer D, Bollen M.

Biosci Rep. 2015 Oct 2;35(6). pii: e00267. doi: 10.1042/BSR20150194.

48.

Myositis Ossificans.

Walczak BE, Johnson CN, Howe BM.

J Am Acad Orthop Surg. 2015 Oct;23(10):612-22. doi: 10.5435/JAAOS-D-14-00269. Epub 2015 Aug 28. Review.

PMID:
26320160
49.

Feral Cats Are Better Killers in Open Habitats, Revealed by Animal-Borne Video.

McGregor H, Legge S, Jones ME, Johnson CN.

PLoS One. 2015 Aug 19;10(8):e0133915. doi: 10.1371/journal.pone.0133915. eCollection 2015.

50.

Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP.

Chessari G, Buck IM, Day JE, Day PJ, Iqbal A, Johnson CN, Lewis EJ, Martins V, Miller D, Reader M, Rees DC, Rich SJ, Tamanini E, Vitorino M, Ward GA, Williams PA, Williams G, Wilsher NE, Woolford AJ.

J Med Chem. 2015 Aug 27;58(16):6574-88. doi: 10.1021/acs.jmedchem.5b00706. Epub 2015 Aug 7.

PMID:
26218264

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